LOCUS       NM_130420               3689 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 9 (Trim9), mRNA.
ACCESSION   NM_130420
VERSION     NM_130420.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3689)
  AUTHORS   Li,J. and Zeng,Q.
  TITLE     Trim9 regulates the directional differentiation of retinal Muller
            cells to retinal ganglion cells
  JOURNAL   Zhong Nan Da Xue Xue Bao Yi Xue Ban 48 (10), 1561-1571 (2023)
   PUBMED   38432885
  REMARK    GeneRIF: Trim9 regulates the directional differentiation of retinal
            Muller cells to retinal ganglion cells.
REFERENCE   2  (bases 1 to 3689)
  AUTHORS   Zeng,Q., Zhou,J. and Hua,X.
  TITLE     TRIM9 promotes Muller cell-derived retinal stem cells to
            differentiate into retinal ganglion cells by regulating Atoh7
  JOURNAL   In Vitro Cell Dev Biol Anim 59 (8), 586-595 (2023)
   PUBMED   37792226
  REMARK    GeneRIF: TRIM9 promotes Muller cell-derived retinal stem cells to
            differentiate into retinal ganglion cells by regulating Atoh7.
REFERENCE   3  (bases 1 to 3689)
  AUTHORS   Zhao,W. and Wang,Q.
  TITLE     Knockdown of TRIM9 attenuates irinotecan-induced intestinal
            mucositis in IEC-6 cells by regulating DUSP6 expression via the P38
            pathway
  JOURNAL   Mol Med Rep 24 (6) (2021)
   PUBMED   34676875
  REMARK    GeneRIF: Knockdown of TRIM9 attenuates irinotecaninduced intestinal
            mucositis in IEC6 cells by regulating DUSP6 expression via the P38
            pathway.
REFERENCE   4  (bases 1 to 3689)
  AUTHORS   Morikawa,R.K., Kanamori,T., Yasunaga,K. and Emoto,K.
  TITLE     Different levels of the Tripartite motif protein, Anomalies in
            sensory axon patterning (Asap), regulate distinct axonal
            projections of Drosophila sensory neurons
  JOURNAL   Proc Natl Acad Sci U S A 108 (48), 19389-19394 (2011)
   PUBMED   22084112
REFERENCE   5  (bases 1 to 3689)
  AUTHORS   Tanji,K., Kamitani,T., Mori,F., Kakita,A., Takahashi,H. and
            Wakabayashi,K.
  TITLE     TRIM9, a novel brain-specific E3 ubiquitin ligase, is repressed in
            the brain of Parkinson's disease and dementia with Lewy bodies
  JOURNAL   Neurobiol Dis 38 (2), 210-218 (2010)
   PUBMED   20085810
REFERENCE   6  (bases 1 to 3689)
  AUTHORS   Li,Y., Chin,L.S., Weigel,C. and Li,L.
  TITLE     Spring, a novel RING finger protein that regulates synaptic vesicle
            exocytosis
  JOURNAL   J Biol Chem 276 (44), 40824-40833 (2001)
   PUBMED   11524423
REFERENCE   7  (bases 1 to 3689)
  AUTHORS   Reymond,A., Meroni,G., Fantozzi,A., Merla,G., Cairo,S., Luzi,L.,
            Riganelli,D., Zanaria,E., Messali,S., Cainarca,S., Guffanti,A.,
            Minucci,S., Pelicci,P.G. and Ballabio,A.
  TITLE     The tripartite motif family identifies cell compartments
  JOURNAL   EMBO J 20 (9), 2140-2151 (2001)
   PUBMED   11331580
REFERENCE   8  (bases 1 to 3689)
  AUTHORS   Koroll,M., Rathjen,F.G. and Volkmer,H.
  TITLE     The neural cell recognition molecule neurofascin interacts with
            syntenin-1 but not with syntenin-2, both of which reveal
            self-associating activity
  JOURNAL   J Biol Chem 276 (14), 10646-10654 (2001)
   PUBMED   11152476
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AF350422.1.
            
            [WARNING] On Oct 22, 2024 this sequence was replaced by
            NM_130420.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AF350422.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132261,
                                           SAMD00132262 [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..3689
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..3689
                     /gene="Trim9"
                     /note="tripartite motif-containing 9"
                     /db_xref="GeneID:155812"
                     /db_xref="RGD:621540"
     exon            1..980
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     CDS             159..2291
                     /gene="Trim9"
                     /EC_number="2.3.2.27"
                     /note="tripartite motif-containing protein 9;
                     SNAP-25-interacting RING finger protein; tripartite motif
                     protein 9; Spring; RING-type E3 ubiquitin transferase
                     TRIM9"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM9"
                     /protein_id="NP_569104.1"
                     /db_xref="GeneID:155812"
                     /db_xref="RGD:621540"
                     /translation="MEEMEEELKCPVCGSFYREPIILPCSHNLCQACARNILVQTPES
                     ESPQSRRASGSGVSDYDYLDLDKMSLYSEADSGYGSYGGFASAPTTPCQKSPNGVRVF
                     PPAMPPPPTHLSPALAPVPRNSCITCPQCHRSLILDDRGLRGFPKNRVLEGVIDRYQQ
                     SKAAALKCQLCEKAPKEATVMCEQCDVFYCDPCRLRCHPPRGPLAKHRLVPPAQGRVS
                     RRLSPRKVSTCTDHELENHSMYCVQCKMPVCYQCLEEGKHSSHEVKALGAMWKLHKSQ
                     LSQALNGLSDRAKEAKEFLVQLRTMVQQIQENSVEFEACLVAQCDALIDALNRRKAQL
                     LARVNKEHEHKLKVVRDQISHCTVKLRQTTGLMEYCLEVIKENDPSGFLQISDALIRR
                     VHLTEDQWGKGTLTPRMTTDFDLSLDNSPLLQSIHQLDFVQVKASSPVPATPILQLEE
                     CCTHNNSATLSWKQPPLSTVAADGYILELDDGSGGQFREVYVGKETMCTVDGLHFNST
                     YNARVKAFNKTGVSPYSKTLVLQTSEVAWFAFDPGSAHSDIIFSNDNLTVTCSSYDDR
                     VVLGKTGFSKGVHYWELTIDRYDNHPDPAFGVARIDVMKDMMLGKDDKAWAMYVDNNR
                     SWFMHNNSHTNRTEGGITKGATIGVLLDLNRKTLTFFVNNEQQGPIAFENVEGLFFPA
                     VSLNRNVQVTLHTGLPVPDFYSSRASIA"
     exon            981..1076
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     exon            1077..1199
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     exon            1200..1310
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     exon            1311..1464
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     exon            1465..1622
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     exon            1623..1761
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     exon            1762..2065
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     exon            2066..2228
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
     exon            2229..3689
                     /gene="Trim9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agagcgcgtc ctggggagtc ggcgcctagg cgacgcggaa aggcgccacc accgccgccg
       61 ctggccaagg tgctggacac cacaggccta tcgactgctt cgccaggtca ggcccccttt
      121 gccgcagcct ctgctgcctc gcttccagcc aggtccccat ggaagagatg gaagaagagt
      181 taaaatgccc cgtgtgtggc tccttctatc gggagcccat catcctgccc tgctctcaca
      241 atttatgcca ggcttgcgcc cgcaacatcc tggtgcagac cccggagtcc gagtcccccc
      301 agagccgccg ggcctcgggc tctggggttt ctgactatga ctatctggac ctggacaaga
      361 tgagccttta cagcgaggcg gacagcggct atggctccta cggaggtttc gccagcgccc
      421 ccactacccc gtgccagaag tcgcccaacg gcgtccgtgt tttcccccct gctatgccgc
      481 caccgcccac ccacctgtca ccggctttgg cccctgtgcc ccgcaactcc tgcattacct
      541 gcccccagtg ccaccgcagc ctcattctgg atgaccgggg gctccgcggc ttccccaaga
      601 accgcgtcct ggaaggggtc atcgaccgct accaacagag caaagccgcg gccctcaagt
      661 gccagctctg tgagaaggcg cccaaggaag ccacggtcat gtgcgaacag tgcgatgtct
      721 tctactgcga cccttgccgt ctacgctgcc acccaccgag gggtccccta gccaaacacc
      781 gtctggtgcc cccggcccag ggtcgcgtaa gccgacggct gagcccgcgc aaggtctcca
      841 cctgcacaga ccacgagctg gagaaccaca gcatgtactg tgtgcaatgc aagatgccgg
      901 tgtgctacca gtgcttggag gagggcaaac actccagcca cgaagtcaag gctttggggg
      961 ctatgtggaa attgcacaag agccagcttt cccaggcgct gaatggattg tcagatagag
     1021 ccaaagaagc caaggagttc ctggtgcaac tccgcaccat ggtgcaacaa atccaggaaa
     1081 acagtgtgga gtttgaagcc tgcctggtgg ctcagtgcga tgctctcatt gatgccctaa
     1141 accgaaggaa ggctcagctg ctggcccggg tcaacaagga acatgagcac aagctgaagg
     1201 tggtccggga ccagatctct cattgcacag tgaaactgcg ccagaccacg ggcctcatgg
     1261 agtactgctt ggaagtgatt aaggagaacg accccagtgg cttcctgcag atttcagatg
     1321 ccctcatcag acgagttcac ttaactgagg accagtgggg aaaaggcaca ctcactccca
     1381 ggatgaccac ggacttcgac ctgagcctgg acaacagtcc tctgctacag tccatccacc
     1441 agctggactt cgtgcaagtg aaagcttcct ctccagtccc agcaaccccc atcctccagc
     1501 tggaggagtg ttgcacccac aacaacagtg ctacgctgtc ctggaaacag ccccctctgt
     1561 ccactgtggc cgccgatggc tacattctgg agctggatga tggcagtggt ggtcagttcc
     1621 gggaagtgta tgttggaaaa gaaacaatgt gcacagtgga tggccttcac ttcaacagca
     1681 catacaacgc ccgcgttaag gccttcaaca aaacaggagt cagcccctac agcaagacac
     1741 tggtcctcca gacgtctgag gtggcgtggt ttgcgtttga ccccggctcg gcacactctg
     1801 acatcatctt ctccaatgac aacctgacag tgacatgcag tagctacgat gaccgggtgg
     1861 tgctggggaa aactggcttc tccaagggcg tccactactg ggagctgacc atagatcgct
     1921 atgacaacca ccctgatcca gcatttggcg tggctcgcat cgatgtgatg aaggatatga
     1981 tgttaggaaa ggacgacaag gcttgggcaa tgtatgtgga caataaccgg agctggttca
     2041 tgcacaacaa ctcgcacacc aacagaactg aaggagggat cacaaaaggg gccactatcg
     2101 gggtcctcct cgacttaaac agaaagacat taacgttttt cgtcaacaat gaacagcaag
     2161 gccccatagc ctttgagaat gtggagggcc tgttctttcc tgccgtcagc ctgaacagga
     2221 atgtacaggt cacgcttcac actgggcttc cggtccccga cttctactcc agcagagctt
     2281 ccatagccta agggtgagct gtggaggcac tggctgtccc tgagaaggac agcccagagc
     2341 ctgcagcctc agcagaggac acagagccgg tagaagaatg agaacagctg gtcctcagca
     2401 atctccacct ttagagctcc accctttccc atcagcctct ccgcatcgct gaacccaggc
     2461 tcccttcctc acccagaaac tctacccgcg cagaggagct ctgcagccca ccgctcccgt
     2521 gtgttcccac ttccgtgtgt tctttttctt taatttagtg ggtttttgtt gttgtttgct
     2581 tgtttgtttg tttttgtttt aatgtaggtt gaattcattt tgattctttt ctgattgtgt
     2641 tttggtgact tacgtacact acctggcact gtcaaaagac attctcctgg aaactttttt
     2701 tcttaagcgt ttggacaaac aaaggtgttc taggagagca ggtaggaaag aagccgaatt
     2761 tagagtttgc catttgactc ctagaatgtt cttgccctgg ttcttgtcaa gcaatgttag
     2821 ttcttcatgg ctacttcttg ggaggtgggc agaagtgcat ttggcatcca gaagtcttac
     2881 tacaccctaa agcacaaata catcatctac actggctcat ggcagggtaa ggaccttcca
     2941 gacaggctct aggtactggg aagaccaggt ggcccaatgg tttgattcat ttgactaata
     3001 caagttttta attaagaact actacggacc aggcactgtt caagacacta gaatgctgtg
     3061 ttcatgaaca gtctgtcttc ctggaactta tattctatgt aacaaagcaa caaataacgt
     3121 caagttgttc taagtaccag aaaggagagg agtcaaagga ggtgtcactg acaaaccctc
     3181 agactgacgc tgaacccaca cactccagcc atcacacaga catgtaccaa cccagtgctt
     3241 ttcccaccgc actaccgtaa ctaaggtctc tgctgccact caccgcagag cccgtcttcg
     3301 gcagaaatga tgtcaccatt gttactcatt agtgctgtgc tcagaacaag ccttaaaagc
     3361 cagaatgtta aaaaacaaca tgaccagagg acacaggacc cagccacaac cctgggcctc
     3421 ccgagttgca aaccacaaca tttacatcct caggataaac atgacatctc catgtatact
     3481 ctctgtgcct gttgcaaatg agactccatc cgctcaccgc tgtcacagcc tgactttcta
     3541 aagaagctca aatcgggttt ggaacagcgt aagtgtggac atcattccta gcattgacag
     3601 aagactaacc aggcttacga ctcttaacgg agtagatacc cttcagatgc ttctgtttga
     3661 cacgaagctt tagagaatgt aggacctgg
//
