LOCUS       NM_001401504            2383 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus tripartite motif containing 68 (Trim68), mRNA.
ACCESSION   NM_001401504 XM_008759840
VERSION     NM_001401504.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2383)
  AUTHORS   Miyajima,N., Maruyama,S., Bohgaki,M., Kano,S., Shigemura,M.,
            Shinohara,N., Nonomura,K. and Hatakeyama,S.
  TITLE     TRIM68 regulates ligand-dependent transcription of androgen
            receptor in prostate cancer cells
  JOURNAL   Cancer Res 68 (9), 3486-3494 (2008)
   PUBMED   18451177
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Feb 14, 2022 this sequence version replaced XM_008759840.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582424.747986.1,
                                           SRR26360186.1452309.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-188               JAXUCZ010000001.1  166539220-166539407 c
            189-648             JAXUCZ010000001.1  166532564-166533023 c
            649-744             JAXUCZ010000001.1  166530101-166530196 c
            745-1005            JAXUCZ010000001.1  166528527-166528787 c
            1006-1028           JAXUCZ010000001.1  166528049-166528071 c
            1029-1129           JAXUCZ010000001.1  166527428-166527528 c
            1130-2383           JAXUCZ010000001.1  166525981-166527234 c
FEATURES             Location/Qualifiers
     source          1..2383
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q32"
     gene            1..2383
                     /gene="Trim68"
                     /note="tripartite motif containing 68"
                     /db_xref="GeneID:684189"
                     /db_xref="RGD:1593867"
     exon            1..188
                     /gene="Trim68"
                     /inference="alignment:Splign:2.1.0"
     exon            189..648
                     /gene="Trim68"
                     /inference="alignment:Splign:2.1.0"
     CDS             223..1680
                     /gene="Trim68"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM68"
                     /protein_id="NP_001388433.1"
                     /db_xref="GeneID:684189"
                     /db_xref="RGD:1593867"
                     /translation="MDPAVLVDAIVEEVNCPICMTLLREPVSITCGHTFCHSCLSGLW
                     RLPGDSQNLSYTCPLCRAPVQPRKLRPNWQLASVVDKVRLLGFCMEMGLKTDMCDLHK
                     EQLTMFCKEDDVVTCKACNKSPEHGAHSVVPIKDVAWEYKWKLQQALEHLRKEQEKVW
                     KLEVSEKEQAAIWKTQMETRKQSILWEFEKYQQLLKEKELPCQQAEEEAAAVQAGLEQ
                     EKGEMGNKLRLRHEKMIQQSQVLWQMIVELEERSQRPVRWMMQGIQEALNRSKSWSLQ
                     QLEPISLELKTDCRVLGLREILKTFAVDVRLDPDTAYSRLVISKDRKSVHYGVTQQNL
                     PDNPERFYRYNIVLGSQCISSGRHYWEVEVGDRSEWGLGVCVESVDRKEVVYLSPRYG
                     FWVIRLRKGTEYRAGTDEYPLLPLSVPPHRVGIFLDYEAHDISFYNVTDAGSHIFTFP
                     RYPFPGRLLPYFSPCYSIGTNNTTPITICTLDGEG"
     exon            649..744
                     /gene="Trim68"
                     /inference="alignment:Splign:2.1.0"
     exon            745..1005
                     /gene="Trim68"
                     /inference="alignment:Splign:2.1.0"
     exon            1006..1028
                     /gene="Trim68"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1129
                     /gene="Trim68"
                     /inference="alignment:Splign:2.1.0"
     exon            1130..2383
                     /gene="Trim68"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctacggaag tcgcgagggc ccagctcttg cctgggctcc cgcgcctccc gctgcggtcg
       61 cggtttctgg cgcgcgggcg cttgctccag cacactgcgg actggagctc tggagccccg
      121 cacctcccct gcggggtact ctgagccgag aaggaggcga cagcaggcct ctttggagga
      181 agacacagcc ttcatgttct gagatgacgg tcacttggaa ccatggatcc tgcagtgtta
      241 gtggatgcca ttgtggaaga agtgaactgt cctatctgta tgaccctcct cagggagcct
      301 gtgagcatca cctgtggcca cactttctgc cacagctgtc tctctggact ctggaggctc
      361 ccaggagact cccagaactt gagctacact tgtccccttt gtcgagctcc cgtgcagcca
      421 aggaaactcc gtcccaattg gcagctggcc agtgttgtag ataaggtccg actgctaggc
      481 ttctgtatgg aaatgggact aaagactgat atgtgtgatc tccacaagga acagctcaca
      541 atgttctgca aagaggatga tgtggtaacc tgcaaggcct gtaacaagtc cccagagcat
      601 ggagcccaca gtgttgtccc cataaaggat gttgcctggg agtataagtg gaaactccag
      661 caagctctgg aacatctgag gaaagaacag gagaaagtct ggaaactgga agtcagtgag
      721 aaggagcaag ctgccatctg gaagacacag atggaaacac gaaagcagag catcctatgg
      781 gagtttgaaa aatatcagca gttgttaaag gaaaaggagc tgccatgtca gcaggcagaa
      841 gaagaggcag ccgccgttca ggctggcctg gagcaggaga agggagagat gggaaacaaa
      901 ctgaggttga ggcacgagaa gatgatccag cagagccagg tcctgtggca gatgattgtg
      961 gagctggaag agaggtccca gagacctgtg cgctggatga tgcagggtat tcaggaagcc
     1021 ttaaacagga gcaagtcttg gagcctgcag cagctagaac caatctcctt ggagctgaag
     1081 acagattgcc gtgtgctagg actaagagag attctgaaga catttgcagt ggatgtgcgc
     1141 ctagatccag acacagctta ctcccgcctt gtcatttcca aggacaggaa aagtgtgcac
     1201 tatggagtca cccagcagaa cctgcctgac aatcctgaga gattttaccg ctacaacatt
     1261 gtcttgggca gccagtgcat ctcctccggc cggcactact gggaagtgga ggttggagac
     1321 agatctgagt ggggcctggg agtgtgtgta gaaagtgtag accggaaaga ggtggtctac
     1381 ttatcccctc gctatggctt ctgggtgata aggctgagga aaggaacaga gtaccgagca
     1441 ggcacagatg aatatccact cctgcccttg tcagttcctc cgcaccgggt aggaatcttc
     1501 ctagactatg aggcccatga catctccttc tacaatgtga ctgatgctgg ctctcatatt
     1561 ttcacttttc ctcgctatcc cttcccgggc cgtctcctgc cctatttcag tccttgttac
     1621 agcattggca ctaacaacac cactccaatc accatttgta ccctggatgg ggaaggctag
     1681 gagagccatc ctaacctaat gttggaattt ggcaggggat gactgttcaa ggatgcttcc
     1741 aatgataaac atattcctga acccacctta aagcccaagg gctcctctag atctgacctt
     1801 acggtatcac tattagaaca aactgccagt gcccctcaga gcaaaatcgt cccagtcaga
     1861 taagcactgt gatccatgat gcaaacatga cagggatgat ggactttgtc cattccggag
     1921 atcctggctt cataattaag tgggtaccgg tgattaaata aatgcagaca ccaggaaagc
     1981 ttttacataa cgttttccag gagactaagt aataaggtac atgcccagag ctgatagtca
     2041 tggtgaaacc aggtagaggt ccttcacatg agacttgctg ctaccaaacc aaccctaacc
     2101 tccattctag agaaacgcag tctgtgcttc tccagcacaa gagtcagagc tcatccagga
     2161 tgctctccgt atctccttcc tgagcatgag gatgggtcta cgtcctgggc ctgtcttttc
     2221 tctaagggac aggaccagaa accttagggg ccttggtttt tatttttact gcatgtataa
     2281 agaaattgaa acagccttct ttcctacaga gctttgaaag atgagattgt aaagcttgta
     2341 aaatgatttt cacattaaaa tgaaacaaag ctgacaaact caa
//
