LOCUS       NM_001108945            2706 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 59 (Trim59), mRNA.
ACCESSION   NM_001108945 XM_001062051
VERSION     NM_001108945.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2706)
  AUTHORS   Liu,Y., Zhu,L., Ming,Y., Wu,Z., Zhang,L., Chen,Q. and Qi,Y.
  TITLE     A role of TRIM59 in pulmonary hypertension: modulating the protein
            ubiquitylation modification
  JOURNAL   J Transl Med 21 (1), 821 (2023)
   PUBMED   37978515
  REMARK    GeneRIF: A role of TRIM59 in pulmonary hypertension: modulating the
            protein ubiquitylation modification.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2706)
  AUTHORS   Kondo,T., Watanabe,M. and Hatakeyama,S.
  TITLE     TRIM59 interacts with ECSIT and negatively regulates NF-kappaB and
            IRF-3/7-mediated signal pathways
  JOURNAL   Biochem Biophys Res Commun 422 (3), 501-507 (2012)
   PUBMED   22588174
REFERENCE   3  (bases 1 to 2706)
  AUTHORS   Uchil,P.D., Quinlan,B.D., Chan,W.T., Luna,J.M. and Mothes,W.
  TITLE     TRIM E3 ligases interfere with early and late stages of the
            retroviral life cycle
  JOURNAL   PLoS Pathog 4 (2), e16 (2008)
   PUBMED   18248090
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473976.2.
            
            On Oct 4, 2007 this sequence version replaced XM_001062051.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CA511585.1, FN802285.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2706
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q32"
     gene            1..2706
                     /gene="Trim59"
                     /gene_synonym="RGD1311956"
                     /note="tripartite motif-containing 59"
                     /db_xref="GeneID:365813"
                     /db_xref="RGD:1311956"
     exon            1..61
                     /gene="Trim59"
                     /gene_synonym="RGD1311956"
                     /inference="alignment:Splign:2.1.0"
     exon            62..2706
                     /gene="Trim59"
                     /gene_synonym="RGD1311956"
                     /inference="alignment:Splign:2.1.0"
     CDS             65..1276
                     /gene="Trim59"
                     /gene_synonym="RGD1311956"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="tripartite motif-containing protein 59"
                     /protein_id="NP_001102415.1"
                     /db_xref="GeneID:365813"
                     /db_xref="RGD:1311956"
                     /translation="MHNFEDELTCPICYSIFDDPRVLPCSHTFCRNCLENVLQASGNF
                     YIWRPLRIPLKCPNCRSIIEIASTGIESLPVNFALRAIIEKYQQEDHPDVVTCPEHYR
                     QPLNVYCLLDKKLVCGHCLTIGQHHGHPIDDLQSAYLKEKDTPQKLFKQLTDTHWTDI
                     TRLIEKLEEQKCHSEKIVQSDKEVVLQYFKELTDTLEQKKKFFLAALCDVGKMINQEY
                     TPQIERMKEIREQQLELMTMTTSLQDESPLKFLEKIDDVRQRVQMLKQRPLPEVQPVE
                     IYPRVSNVLKEEWSRTEIGRIKKAVIPEMRISSKRMPCSWPDKDEKEMECFKILNIAI
                     VSLISVILMLILLFNHHIITFLNEITSICFSEVFLSVYQSLSKNLYDLKNTVCYTLYL
                     LKEFMWKIVSC"
ORIGIN      
        1 ctggaaaagt tgaagaagat aaagtatatt cagtatccag atcaggagat taacagacca
       61 ggaaatgcac aattttgagg acgagttaac ctgtcccatt tgttatagta tctttgacga
      121 tcctcgtgta ctaccatgct ctcatacatt ttgtagaaac tgtttggaaa atgttcttca
      181 ggcatctggt aacttttaca tatggagacc tctgcgaatc ccactcaagt gtcctaactg
      241 cagaagtatt attgaaattg cttcgactgg catagaatcc ttacctgtaa actttgcatt
      301 aagagcaatt attgaaaagt accagcaaga agaccaccca gatgttgtca cctgccctga
      361 acattacagg caaccattaa atgtttattg tctactagat aaaaaattag tttgtggcca
      421 ttgtcttact ataggtcaac atcatggcca tcctatagat gaccttcaaa gtgcctatct
      481 gaaagaaaag gatacacctc agaagttgtt taaacagtta accgacacac actggacaga
      541 tatcactcgc cttattgaaa agcttgaaga acagaaatgt cattctgaga aaatcgttca
      601 aagtgataag gaagttgttc tccagtattt taaggagctt actgatacgt tagaacagaa
      661 aaaaaaattt tttctggcag ctctctgtga tgttggcaag atgattaatc aagaatacac
      721 tccacagatt gaaaggatga aggaaataag agaacaacaa cttgagttaa tgacaatgac
      781 aacatcttta caagatgaat ctccacttaa atttcttgaa aaaattgatg atgttcgcca
      841 acgtgtgcag atgttgaaac agagaccact tcctgaggtc cagcctgttg aaatttatcc
      901 tcgagtaagc aatgtattaa aagaagagtg gagcagaaca gaaattggac gcattaagaa
      961 agctgtcatc cctgaaatga gaatctcttc aaaaaggatg ccatgttcct ggcctgataa
     1021 ggatgaaaaa gaaatggaat gttttaaaat tttaaacatt gctatagttt cactaatttc
     1081 agtgatacta atgctgatac tccttttcaa ccatcacata ataaccttct taaatgaaat
     1141 cacttccata tgtttctctg aagtctttct ctctgtttac caaagtttat ctaagaactt
     1201 atatgactta aaaaacacag tatgctacac tttatatttg ttaaaggaat ttatgtggaa
     1261 aatagtgtct tgttgaaaac ccaatttacc agtttcatgt aggtgtattc tgtatagcag
     1321 aggctaagta ttggttggca gattgaaagg tcagggtggc ataaggagca aataaacatc
     1381 tttagagaca cacagaaata cgacaggttt cccaaggtgg ggtagaagtg gtcagaaagg
     1441 agacattatc tgaaaggcaa ctcaaatcaa attagaaaac gacaagtttt gttttgagta
     1501 tgactactgt accttgcttt tattggctta ctagtcaatg ctttattctg tttagtgttt
     1561 caactgctac atacagtgct taactttgca gttctttgta tatgcagatg taagattata
     1621 aaagatgaca agctccttga ggtccacaag cctagtttga taggatttga agcttttcaa
     1681 tgtatagatg gagatgacat agaagttgtt taaaaaaatc taggccagga ttgtttaaac
     1741 accttttttg gtcaattaat agatttcaga gcattcatcc caaccagctg cttgctgctt
     1801 ttggataaat catctgtgtt tagcacggag ttcaattcag ccttgatatc agtgaggtct
     1861 caaaaaccaa ccaaaaagtt acagtgctag agagccccct gcctgggctg ctggctccag
     1921 cactgcaaag caaaccaagt atgtatttga ttttgtggtg ttttaatctt atttttagat
     1981 gaaaattata tgaaacgtat attaagacaa tcatgttgat gtgattcatt taataggttt
     2041 ggtatcatgt atgctatatt catcttaaaa tgggctcacc ctgtagctca tgtactaggg
     2101 tttcactgag ctgccactat ctgtttagtc ttgaaaagag gtcattaagt tggaaccttt
     2161 aatttttgat agggacaacc atgatgcatg tggtataact ttggttcact gccattaaaa
     2221 ttgaaaaaca ttccagaaac cccaaatgag gtgctcttga attatcatct ttggacctta
     2281 tttcaagtat cactaagtcc acttatcaga gtcagatttt atctaacagt tactatatac
     2341 tgaggccatt ttgaagttga gaaagaatgg tcagttttta acagatacct gtcattgtgt
     2401 tattttttta aatgtacata ttagcaggtg aagaacatta gctaaggcat ttttcaaggg
     2461 gttactaact ttgtatagat gaggaaataa agtgcagtgt tggtgttagc aggtgggaga
     2521 gaaactgaaa cttctatttt agtgtaaaac agcatatacc cagtattacc tttaggcttt
     2581 gtattgatat acttgtttta tatttttacc aggaggttga gtttgtacaa cttaaaatgc
     2641 atacatttgg aaattctggg ttttatgtct aacagtatat tttaataaac ttgacatttt
     2701 attgaa
//
