LOCUS       NM_001191641            1458 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 58 (Trim58), mRNA.
ACCESSION   NM_001191641 XM_220473
VERSION     NM_001191641.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1458)
  AUTHORS   Thom,C.S., Traxler,E.A., Khandros,E., Nickas,J.M., Zhou,O.Y.,
            Lazarus,J.E., Silva,A.P., Prabhu,D., Yao,Y., Aribeana,C.,
            Fuchs,S.Y., Mackay,J.P., Holzbaur,E.L. and Weiss,M.J.
  TITLE     Trim58 degrades Dynein and regulates terminal erythropoiesis
  JOURNAL   Dev Cell 30 (6), 688-700 (2014)
   PUBMED   25241935
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            On Jul 17, 2010 this sequence version replaced XM_220473.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643284.13265.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680412, SAMN06680413
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-417               JAXUCZ010000010.1  43523404-43523820
            418-513             JAXUCZ010000010.1  43525803-43525898
            514-744             JAXUCZ010000010.1  43528908-43529138
            745-767             JAXUCZ010000010.1  43529967-43529989
            768-868             JAXUCZ010000010.1  43530083-43530183
            869-1458            JAXUCZ010000010.1  43533830-43534419
FEATURES             Location/Qualifiers
     source          1..1458
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..1458
                     /gene="Trim58"
                     /gene_synonym="RGD1566174"
                     /note="tripartite motif-containing 58"
                     /db_xref="GeneID:303167"
                     /db_xref="RGD:1566174"
     CDS             1..1458
                     /gene="Trim58"
                     /gene_synonym="RGD1566174"
                     /EC_number="2.3.2.27"
                     /note="tripartite motif-containing protein 58"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM58"
                     /protein_id="NP_001178570.1"
                     /db_xref="GeneID:303167"
                     /db_xref="RGD:1566174"
                     /translation="MATAPGERLQEEARCSVCLDFLQEPISVDCGHSFCLRCISELCE
                     KSDSAQGVYACPQCRGPFRPSSFRPNRQLASLVDTVRQLGLGTGHAGSRQCSRHGEDL
                     SHFCEEDQAMVCWVCDTSPEHRSHRTEPLQEAASRYQRMLQVALELVKKEMEEALTQE
                     ANVGKKTIIWKEKVEMQRQRFRLEFEKHRGFLAQEEQLQLRRLEEEERATLQRLRDSR
                     NRLAQQNKALKELAEELEEMSQRPAVALLEGARGVLTRSEAMTRLEPEAVPMELKTVC
                     RIPGMREMLRKFQVDVKLDPATAHPSLLLTTDLRSVQDAEVWRDVPSNPERFDTWPCI
                     LGLQGFSSGRHYWEVIVGERAEWGLGVCQDSVLRKGETTPSPENGVWAMWLLRGSEYM
                     VLSSPSVPVFQDERPRRIGIFLDYEAGQISFYNVTNGSYIYTFNHLFSGVLRPYFFVC
                     DTTPLILPPMTEAGPGNWTSRGLLDFAVAARSEEY"
     exon            1..417
                     /gene="Trim58"
                     /gene_synonym="RGD1566174"
                     /inference="alignment:Splign:2.1.0"
     exon            418..513
                     /gene="Trim58"
                     /gene_synonym="RGD1566174"
                     /inference="alignment:Splign:2.1.0"
     exon            514..744
                     /gene="Trim58"
                     /gene_synonym="RGD1566174"
                     /inference="alignment:Splign:2.1.0"
     exon            745..767
                     /gene="Trim58"
                     /gene_synonym="RGD1566174"
                     /inference="alignment:Splign:2.1.0"
     exon            768..868
                     /gene="Trim58"
                     /gene_synonym="RGD1566174"
                     /inference="alignment:Splign:2.1.0"
     exon            869..1458
                     /gene="Trim58"
                     /gene_synonym="RGD1566174"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggccacag cacccgggga gcggctgcag gaggaggcac ggtgctcagt gtgcctggac
       61 ttcctgcagg agcccatcag cgttgactgt ggtcacagct tctgtctgcg gtgcatatct
      121 gagctctgcg agaaatcgga cagcgctcag ggagtctatg cttgtcccca gtgcaggggt
      181 cccttcaggc cctccagctt cagacccaac cggcagctgg ccagcctggt ggacaccgtg
      241 cggcagctgg ggctgggcac cggacacgcg gggtcgcgtc agtgttcgag gcacggtgag
      301 gacctgagcc acttctgtga agaggaccaa gcgatggtgt gctgggtctg cgacaccagc
      361 cctgagcacc ggagccaccg cactgagccg ctgcaggagg cagccagccg ctaccagagg
      421 atgctccaag tggctttgga acttgtgaag aaggaaatgg aggaggctct gacccaggag
      481 gccaacgtgg gaaagaagac catcatctgg aaggagaaag tggagatgca gagacaacgt
      541 ttcaggctgg agtttgagaa acaccggggc tttctggccc aggaggagca gctgcagctg
      601 aggcgactgg aagaggagga gcgagcaacc ctgcagagac tgcgtgacag taggaacagg
      661 ctggcccaac agaacaaagc cctgaaggaa ctggctgaag agctggagga gatgagtcag
      721 aggccagcgg tagcactgct ggagggagcg agaggagtct tgacgcgaag cgaagctatg
      781 accaggctgg aaccagaggc tgtccctatg gagctgaaga ccgtgtgccg catccctggg
      841 atgagggaga tgctgaggaa gttccaagtg gacgtgaaac tcgatcccgc cactgcccac
      901 ccaagcttgc tcttaacgac ggatctgcgc agtgtgcagg atgcggaggt ctggagggat
      961 gtcccgagca accctgagcg ctttgacacc tggccctgca tcctgggcct gcagggcttc
     1021 tcctccggga ggcattactg ggaagtcatc gtgggggaaa gagcagagtg ggggctaggg
     1081 gtctgccaag actcagtgct tagaaaaggg gagaccacac cgtccccaga gaatggtgtc
     1141 tgggccatgt ggctcctgag ggggagcgag tacatggtcc tgtcctctcc ctcggtgcct
     1201 gtgttccaag atgagcgacc tcgtcgcatc gggatctttt tggactacga agccggccaa
     1261 atctccttct acaatgtcac aaatgggtct tacatctaca catttaacca tctcttctcc
     1321 ggtgttctca ggccctattt cttcgtctgt gacacaactc ctcttatctt gccacccatg
     1381 acagaagcag gacctggaaa ctggacttcc aggggtctcc ttgattttgc tgttgctgcc
     1441 agaagtgagg aatactaa
//
