LOCUS       NM_001106056             880 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 52 (Trim52), mRNA.
ACCESSION   NM_001106056 XM_001077454 XM_224468
VERSION     NM_001106056.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 880)
  AUTHORS   Ma,T., Wu,C.B., Shen,Q.X., Wang,Q. and Zhou,Q.
  TITLE     TRIM52 knockdown inhibits proliferation, inflammatory responses and
            oxidative stress in IL-1beta-induced synovial fibroblasts to
            alleviate temporomandibular joint osteoarthritis
  JOURNAL   J Cell Mol Med 28 (8), e18244 (2024)
   PUBMED   38520211
  REMARK    GeneRIF: TRIM52 knockdown inhibits proliferation, inflammatory
            responses and oxidative stress in IL-1beta-induced synovial
            fibroblasts to alleviate temporomandibular joint osteoarthritis.
REFERENCE   2  (bases 1 to 880)
  AUTHORS   Zhang,P., Wu,Y., Li,R., Lv,H. and Yu,B.
  TITLE     Tripartite Motif Containing 52 Positively Regulates NF-kappaB
            Signaling by Promoting IkappaBalpha Ubiquitination in
            Lipopolysaccharide-Treated Microglial Cell Activation
  JOURNAL   Med Sci Monit 26, e925356 (2020)
   PUBMED   33122622
  REMARK    GeneRIF: Tripartite Motif Containing 52 Positively Regulates
            NF-kappaB Signaling by Promoting IkappaBalpha Ubiquitination in
            Lipopolysaccharide-Treated Microglial Cell Activation.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 880)
  AUTHORS   Fan,W., Liu,T., Li,X., Zhou,Y., Wu,M., Cui,X., Chen,H. and Qian,P.
  TITLE     TRIM52: A nuclear TRIM protein that positively regulates the
            nuclear factor-kappa B signaling pathway
  JOURNAL   Mol Immunol 82, 114-122 (2017)
   PUBMED   28073078
REFERENCE   4  (bases 1 to 880)
  AUTHORS   Fan,W., Wu,M., Qian,S., Zhou,Y., Chen,H., Li,X. and Qian,P.
  TITLE     TRIM52 inhibits Japanese Encephalitis Virus replication by
            degrading the viral NS2A
  JOURNAL   Sci Rep 6, 33698 (2016)
   PUBMED   27667714
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 880)
  AUTHORS   Uchil,P.D., Hinz,A., Siegel,S., Coenen-Stass,A., Pertel,T.,
            Luban,J. and Mothes,W.
  TITLE     TRIM protein-mediated regulation of inflammatory and innate immune
            signaling and its association with antiretroviral activity
  JOURNAL   J Virol 87 (1), 257-272 (2013)
   PUBMED   23077300
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473951.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_224468.3, XM_001077454.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignment to the mouse ortholog (NM_198601.4).
FEATURES             Location/Qualifiers
     source          1..880
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15q22"
     gene            1..880
                     /gene="Trim52"
                     /gene_synonym="RGD1565615"
                     /note="tripartite motif-containing 52"
                     /db_xref="GeneID:290458"
                     /db_xref="RGD:1565615"
     exon            1..43
                     /gene="Trim52"
                     /gene_synonym="RGD1565615"
                     /inference="alignment:Splign:2.1.0"
     exon            44..96
                     /gene="Trim52"
                     /gene_synonym="RGD1565615"
                     /inference="alignment:Splign:2.1.0"
     exon            97..880
                     /gene="Trim52"
                     /gene_synonym="RGD1565615"
                     /inference="alignment:Splign:2.1.0"
     CDS             97..804
                     /gene="Trim52"
                     /gene_synonym="RGD1565615"
                     /codon_start=1
                     /product="tripartite motif-containing 52"
                     /protein_id="NP_001099526.1"
                     /db_xref="GeneID:290458"
                     /db_xref="RGD:1565615"
                     /translation="MAAPTGPPSPMQSLREEAVCAICLDYFKDPVSIGCGHNFCRGCV
                     TQLWGKEDEQDREPPAVGNHVIREVLFHRYTEQEVFQHRAHAGRWAAHSHRRHRGNAD
                     SVWDDEEEDWNSLQGLVHDLRIRVFPEERDEHPHDGHQYHHYGRYRHRPVFRRGPPHP
                     PVRRQLYPDARPRSPPRVRSPPRVHSPPRVRSPPRPTSQVFSCPQCRRTFPSRSFRPN
                     LQLANMVHIIRQICHTP"
ORIGIN      
        1 ggccggaaga acttgttttc gagcgcgttg acgtcatttc caggctccag tcagctgcgt
       61 ggtcctgcgc cagcggcttc cggagcgagg gctgccatgg ccgcccctac agggcctccc
      121 agccctatgc agtcacttcg ggaagaagca gtatgtgcca tctgtctgga ttactttaag
      181 gaccccgtgt ccattggctg tgggcacaac ttctgccgag ggtgtgtgac ccagctgtgg
      241 ggcaaggaag atgaacagga ccgggaaccg cctgctgtag ggaaccacgt cattagagag
      301 gttttgtttc ataggtacac agaacaggag gtgtttcagc accgagcaca tgctggacgc
      361 tgggctgctc atagccatag aaggcatcgg ggcaatgcag actctgtgtg ggatgatgag
      421 gaagaagact ggaacagttt acaaggactg gtacatgacc tgagaattag ggtttttcca
      481 gaagaaagag atgaacaccc ccacgatggc caccaatacc atcactatgg ccgataccga
      541 caccgtccag ttttccgccg tggtccccca catccacctg tgcgtcggca gctctatcca
      601 gatgcccgac cacgatctcc acctcgagta cgatctccac ctcgagtaca ttctccacct
      661 cgagtacgtt ctccacctcg tcccacatca caggtcttca gctgcccaca atgccgaagg
      721 acatttccaa gtcgcagttt tcgacccaat ttgcagctgg ccaacatggt ccatataatt
      781 cgccagattt gccatacgcc atgaaattag caaagcatgc aaatatgagg aaacctggag
      841 ctctccagtg aggtagaaaa aaagctcatc tgtatggtgt
//
