LOCUS       NM_001013203            5561 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 44 (Trim44), mRNA.
ACCESSION   NM_001013203 XM_342472
VERSION     NM_001013203.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5561)
  AUTHORS   Jiang,X.Y., Guan,F.F., Ma,J.X., Dong,W., Qi,X.L., Zhang,X.,
            Chen,W., Gao,S., Gao,X., Pan,S., Wang,J.Z., Ma,Y.W., Zhang,L.F. and
            Lu,D.
  TITLE     Cardiac-specific Trim44 knockout in rat attenuates
            isoproterenol-induced cardiac remodeling via inhibition of AKT/mTOR
            pathway
  JOURNAL   Dis Model Mech 16 (5) (2023)
   PUBMED   35855640
REFERENCE   2  (bases 1 to 5561)
  AUTHORS   Zhu,L., Dong,C., Yue,X., Ge,P., Zheng,G., Ye,Z. and Pan,B.
  TITLE     Silencing of TRIM44 Inhibits Inflammation and Alleviates Traumatic
            Brain Injury in Rats by Downregulating TLR4-NF-kappaB Signaling
  JOURNAL   Neuroimmunomodulation 29 (4), 439-449 (2022)
   PUBMED   35609523
  REMARK    GeneRIF: Silencing of TRIM44 Inhibits Inflammation and Alleviates
            Traumatic Brain Injury in Rats by Downregulating TLR4-NF-kappaB
            Signaling.
REFERENCE   3  (bases 1 to 5561)
  AUTHORS   Zhang,X., Qin,G., Chen,G., Li,T., Gao,L., Huang,L., Zhang,Y.,
            Ouyang,K., Wang,Y., Pang,Y., Zeng,B. and Yu,L.
  TITLE     Variants in TRIM44 Cause Aniridia by Impairing PAX6 Expression
  JOURNAL   Hum Mutat 36 (12), 1164-1167 (2015)
   PUBMED   26394807
REFERENCE   4  (bases 1 to 5561)
  AUTHORS   Yang,B., Wang,J., Wang,Y., Zhou,H., Wu,X., Tian,Z. and Sun,B.
  TITLE     Novel function of Trim44 promotes an antiviral response by
            stabilizing VISA
  JOURNAL   J Immunol 190 (7), 3613-3619 (2013)
   PUBMED   23460740
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000003.1.
            
            On Nov 8, 2022 this sequence version replaced NM_001013203.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.8471.1,
                                           SRR26643285.12496.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN16676787, SAMN16676808
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-852               JAXUCZ010000003.1  109182970-109183821 c
            853-930             JAXUCZ010000003.1  109166413-109166490 c
            931-1170            JAXUCZ010000003.1  109129061-109129300 c
            1171-1190           JAXUCZ010000003.1  109126091-109126110 c
            1191-5561           JAXUCZ010000003.1  109048643-109053013 c
FEATURES             Location/Qualifiers
     source          1..5561
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q32"
     gene            1..5561
                     /gene="Trim44"
                     /note="tripartite motif-containing 44"
                     /db_xref="GeneID:362172"
                     /db_xref="RGD:1304877"
     exon            1..852
                     /gene="Trim44"
                     /inference="alignment:Splign:2.1.0"
     CDS             184..1218
                     /gene="Trim44"
                     /note="DIPB protein; tripartite motif protein 44"
                     /codon_start=1
                     /product="tripartite motif-containing protein 44"
                     /protein_id="NP_001013221.1"
                     /db_xref="GeneID:362172"
                     /db_xref="RGD:1304877"
                     /translation="MASGVGAACEELPPDGTCDECEPDEAPGAEEVCRDCGFCYCRRH
                     ADAHRQKFLSHRLAAYVHGAQAWTPPASGDDALPEDVEAKGEAEGEVESEVGEEESES
                     EVDSESEEESETEEDSEDESDEESEEDSEEEMEDEQESEAEEDNQEGESEAEGETEAE
                     SEFDPEIEMEAERVAKRKCPDHGLDLSTYCQEDRQLICVLCPVIGAHRGHQLSTLDEA
                     FEELRSKDSGGLKAAMIELVERLKFKSSDPKVTRDQMKVFIQQEFKKVQKVIADEEQK
                     ALHLVDIQEAMATAHVTEILADIQSHMDRLMTQMAQAKEQLDTSNESAEPKAEGDEEG
                     PSGASEEEDT"
     exon            853..930
                     /gene="Trim44"
                     /inference="alignment:Splign:2.1.0"
     exon            931..1170
                     /gene="Trim44"
                     /inference="alignment:Splign:2.1.0"
     exon            1171..1190
                     /gene="Trim44"
                     /inference="alignment:Splign:2.1.0"
     exon            1191..5561
                     /gene="Trim44"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gagtgggcgc caggcccagc gctgacggct ggccgggccc tcaggcctca gcagctgcag
       61 acgcggcgca gcggagcggg gcggctggcc agtccccggg gaggcgggcc tgcgtgagga
      121 ggccccgcgg cgaaggcgga gagtacgcaa gctgctaggc ctcggcctcg tccctgcagc
      181 cacatggcct ccggagtggg cgcggcctgc gaggagctgc ctcccgacgg cacgtgtgac
      241 gagtgtgaac ccgacgaggc gcccggggcg gaggaggtgt gccgcgattg cggcttctgc
      301 tactgccgcc gccacgctga cgcgcaccgc cagaagttcc tcagccaccg cctggccgcg
      361 tacgtccatg gcgcccaggc ctggactccg ccagccagcg gggacgacgc gctccccgaa
      421 gacgtcgagg ccaaagggga ggccgagggg gaggtagaga gcgaggtcgg ggaagaagag
      481 agcgagtcgg aggtagacag tgagtcggaa gaagagagcg agacagagga agacagtgag
      541 gatgagagtg atgaggagag tgaagaagac agcgaggaag agatggaaga tgagcaggaa
      601 agtgaggcgg aggaagacaa ccaagaagga gaatctgagg cagaagggga aactgaggca
      661 gaaagcgaat ttgaccccga aatagagatg gaagcggaga gagtggccaa gaggaagtgt
      721 ccagaccatg ggctggattt gagcacctat tgccaggaag ataggcagct tatctgtgtc
      781 ctgtgtccag tcattggggc tcaccggggc caccagctgt ccacgttaga tgaagccttc
      841 gaagagctga gaagcaaaga ttctggtgga ctgaaggcag ctatgataga gttggtggaa
      901 aggttaaagt tcaagagctc agatcctaaa gtaactcgag accaaatgaa agtatttata
      961 cagcaagaat ttaagaaagt tcagaaagtg attgctgatg aggagcagaa ggctcttcat
     1021 ttagtggaca tccaagaagc aatggccacg gctcatgtga ctgagatatt ggcggacatc
     1081 caatctcaca tggataggtt gatgactcag atggcccagg ccaaggaaca acttgatacc
     1141 tctaatgaat cagctgagcc aaaggcagag ggtgatgagg aaggacccag tggtgccagt
     1201 gaagaagagg acacatgaag actcaccatt ccctgcagaa aatacccctt ccctgtgtgt
     1261 atgtgacagt gtgtatgtaa tggcttctga tatctgtgaa agctgcccgg caacaaactt
     1321 cttccactgg atatgtcccc agatccacag caggcacacg tttccaaggg accagggatt
     1381 gtatgcatac tgactgtgtg cttcttgttc tcttgtgata ggtcatgggg gagccccttt
     1441 gatcaacttg gagggctctt cagacaactc cccaatggct gctttgaact tactcaggaa
     1501 agccagcccc tggattatta ttgtgcaagt caacagtatc actttcttag gaagatctag
     1561 aacatctcga aaggaaatca gttttcctta cctgcaaaca gaaaacccac tttgtttata
     1621 ctgaagctta aagcaaatgt ggccaagtgg ggccaaactg actcaggagg cagtctgtca
     1681 tggtccagtc ctgcctctgt gaaaagtgtt agagcagctg ggctgaaata gggttggaga
     1741 aagagtccag agctagaaag aagatatttt tagtatgtga agttatctag gacttcagat
     1801 tcataattca gtgctgtgga aatggaaaaa aaatgattga aatggtggaa aggaaatgac
     1861 cttaaggact ggggtgaggc aaagaaatct gattaaaagt tgaaatcagt gtttcagaat
     1921 tcagattgcc cgaattttcc aaaatggtca caaaagcatc tgataaaaac ctgaattctt
     1981 gggccagctg tgtggattaa cgggcttgtc acaacataaa aggctggcat gtatattggc
     2041 aggtggagat tgtcactgta aaacttagta gttccactct gaggttagtc tgtcgtggtc
     2101 agtgcactat gaggggaatc cttgccactc cctggctgct aacaagcatt ccctctattt
     2161 actataattg gaatcctcct ttctcttgca gcaggccttc ggttcacctc acacacccca
     2221 gttttctctt tatgtagcat gtccaggcat gccccacagc taggtttcct ggccatctca
     2281 tactagcaga tcacagtctc ttatgaccat acttttcagg gtcaaggaag aaatagtgtg
     2341 ctaggagata cccaactgca agctcacaaa caccatatct tcttgagaca ttagtttttc
     2401 tttccaactg atttaaagtc aggggtaact gtatttttaa tagaacaaac acgttataga
     2461 agagaatgtc catacactta aatcgttaac ataaaatagg agacttggaa ggaaactctt
     2521 atttgtaagt ggacatgatt ccctctcctc ttcgtgtgtg gtatttccat gtacacgcag
     2581 agattctgtc cgaactggat tcaagcagcc ttggggttgc tgttgaccaa ggtctagact
     2641 tccagatcca aggagtccct gttgggataa atctcccttt tcctgtcatc tagcttgcct
     2701 gtgtacttac cacaaagctt taggggcagc taacatgtgt atgtacagga tagttctaag
     2761 gcagaaacaa catatgttta tgtaggagtc ctgtttatgt cattgttcat ccctatgcat
     2821 gctagaaaat gatttatccc tttgaggcca ggaaactgcc aagcctgatt ctctaggcta
     2881 ggattaccct agttcactac acatacaaga atactggggc agagaggagt gtaagatcaa
     2941 aagatacttt tctccaaact ggtagctagt agatggctta gacaattttg gtgctttacc
     3001 atctgtctgc aaagactgga gaatttaata catctagagt taacaacctc caatgagatc
     3061 ctattctaac aaaaatttaa aagatagacc attctagaaa gagtgtagaa tatcagaaga
     3121 ttgaaaaggc ttgacaattt ggaagcttgt attgtctttc cccagtaatc attgatcttt
     3181 acatgttgac cttcattagc aatgaaggga tcattgcctc tccacccaat catgctatta
     3241 ctttcaatca gtgtttgggg aatccaagca tttgtacagt tgttataaac acaaatctaa
     3301 gaagatttgc caacccgtct ctattagtta tcatctctag agtcctcaag gaaagcattt
     3361 gccctttact tagaaagggt ttcaggttca ctttatgggt tcctgctgtc ttcagcacct
     3421 gataaaactt taaccaggaa agcattaaac atttcatagc agcccctgcc tagatcccta
     3481 agttcctagt gacagcaatt atcaatgtaa gaactaggat gcttcctgta ctggtatcag
     3541 cttcgtcctc agagctatga cctcttgctt ggctttgtgt cccatagtga acgaagcttc
     3601 ttgcttttcc aggtcagtgt gagttaagaa tgtcagagtt gtatgtgtcc tggcagacta
     3661 tggacagcaa ggtttaccca aatcatcaag tgatgcaggt aatgaatgtc tctaaaataa
     3721 gttgggtcct ccaaacaagt cctggatacc ttctgaatgt taagtgtcta agtgctgaga
     3781 gtaattggtt cattggtttg ataccactac atctagcgca gttctaagaa gtgcttgact
     3841 tctcagctct gacagccagt aagaagaagt aaccttagga caggctatga gcctctctgt
     3901 agatgtgcaa gggacaagtc acttgtctgt agttgctagc aaaacaatgg aaccagtttt
     3961 gaacacagca ctccctgagc tgtagtcagc cttctgcccc acatcatgac tcacctacag
     4021 attgaaagag aggttttcag ttctcccagt gcagtatgcc cattcacact atgaattcct
     4081 tttcaaagac atcaagatgg ccttagtcct ctactctagt aaatgtgtaa gtattcactg
     4141 ttaacctgag cttccttcca ggacctggga gagcctttct ttttggtaca atccccacaa
     4201 aggaaaataa aggccttcaa gagtgtaaag tttttagaca gagttggagg tgatggtagt
     4261 cttctaactt tatttaaata ccacctgctc ctttactata gaaaagcaaa tgtttatgtt
     4321 ttaggaaacc cagctaccaa gtctgtactc tatgagaggt gccaattcaa atcactaact
     4381 ttgaactccc ttcctggaga ggggtgggtt gatttgtaca cacccacata cactatacca
     4441 cttaattatt taagagttaa gtgaagctca aagcagctcc tggtgatgtt atataccaca
     4501 aaggtttctc ctaggtccat gtaagtataa acagataatt gggagtgtgg ctgctggctt
     4561 tccagaataa ccccgtggta ggtgtcaact cttacagcac taagccaagg tgacatccca
     4621 accctcttcc accatgacta ataacatggg aaatgcagat gccttgtcat ttggtgacct
     4681 ggatcatttt gtcactccat ctgggcccga atatagaact gcaaaattta taaccttgta
     4741 gtagtcagtg gtctaagaag tcctctctct ccacagagaa aatgtcctgc tgattcctga
     4801 tattctactc atgaagtagg tgctcggtac acacgtctct ataaattggt tgcatgttta
     4861 ccatgtgctg agcacatcta gatttttgtt tgtttaaagg caaaagtccc attataaatc
     4921 aagtccagcc ctgccctaag agaaaaggcc cacagagcca tagcacatct cactgacgct
     4981 gccttcaccc atcagtgttt ctgaggccca ctgtcctata gaattcccag agccacagga
     5041 gccaggcatt cctcagatca cacaagagat catttggatc gcttggttcc ccattactat
     5101 ctggggctga gcagaaacac tagaacaagg accagagcag gaacatggag ataaatgaag
     5161 acacttggag tgcactgttg ggaaaatagc cagagtccat gctgggctta atgtggcttt
     5221 aaggggacca gtcgtttata ctttatggaa gttaaacctg accagtcttt gcagtgacag
     5281 gccaccatgc gtgagtgggt cgaaccaacg agtccattgt cttctgcctg ttgtcctgta
     5341 cacagtcaca ttccctcctt ggtcatcttc cccttccacc gtttacacta aacaagggaa
     5401 cactcagtct ttcaagggaa ttacatatct gagttaatgt ttcagtatat cattttcata
     5461 ctgtaaatta ttttgtaaga gagatttact gctatcccag gatgttcgga cttggctccc
     5521 ctgtgcattt ggaaatcaat aaactattac tggaaatacc a
//
