LOCUS       NM_213562               2904 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 39 (Trim39), mRNA.
ACCESSION   NM_213562 XM_227954
VERSION     NM_213562.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2904)
  AUTHORS   Suzuki,M., Watanabe,M., Nakamaru,Y., Takagi,D., Takahashi,H.,
            Fukuda,S. and Hatakeyama,S.
  TITLE     TRIM39 negatively regulates the NFkappaB-mediated signaling pathway
            through stabilization of Cactin
  JOURNAL   Cell Mol Life Sci 73 (5), 1085-1101 (2016)
   PUBMED   26363554
REFERENCE   2  (bases 1 to 2904)
  AUTHORS   Zhang,L., Mei,Y., Fu,N.Y., Guan,L., Xie,W., Liu,H.H., Yu,C.D.,
            Yin,Z., Yu,V.C. and You,H.
  TITLE     TRIM39 regulates cell cycle progression and DNA damage responses
            via stabilizing p21
  JOURNAL   Proc Natl Acad Sci U S A 109 (51), 20937-20942 (2012)
   PUBMED   23213251
  REMARK    Erratum:[Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):4148]
REFERENCE   3  (bases 1 to 2904)
  AUTHORS   Woodsmith,J., Jenn,R.C. and Sanderson,C.M.
  TITLE     Systematic analysis of dimeric E3-RING interactions reveals
            increased combinatorial complexity in human ubiquitination networks
  JOURNAL   Mol Cell Proteomics 11 (7), M111.016162 (2012)
   PUBMED   22493164
REFERENCE   4  (bases 1 to 2904)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
REFERENCE   5  (bases 1 to 2904)
  AUTHORS   Lee,S.S., Fu,N.Y., Sukumaran,S.K., Wan,K.F., Wan,Q. and Yu,V.C.
  TITLE     TRIM39 is a MOAP-1-binding protein that stabilizes MOAP-1 through
            inhibition of its poly-ubiquitination process
  JOURNAL   Exp Cell Res 315 (7), 1313-1325 (2009)
   PUBMED   19100260
REFERENCE   6  (bases 1 to 2904)
  AUTHORS   Hurt,P., Walter,L., Sudbrak,R., Klages,S., Muller,I., Shiina,T.,
            Inoko,H., Lehrach,H., Gunther,E., Reinhardt,R. and Himmelbauer,H.
  TITLE     The genomic sequence and comparative analysis of the rat major
            histocompatibility complex
  JOURNAL   Genome Res 14 (4), 631-639 (2004)
   PUBMED   15060004
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BX883050.1.
            
            On Aug 30, 2004 this sequence version replaced XM_227954.2.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2904
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2904
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /note="tripartite motif-containing 39"
                     /db_xref="GeneID:309591"
                     /db_xref="RGD:1303115"
     exon            1..112
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /inference="alignment:Splign:2.1.0"
     exon            113..570
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /inference="alignment:Splign:2.1.0"
     CDS             118..1584
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /EC_number="2.3.2.27"
                     /note="tripartite motif protein 39; tripartite
                     motif-containing protein 39; RING finger protein 23;
                     RING-type E3 ubiquitin transferase TRIM39"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM39"
                     /protein_id="NP_998727.1"
                     /db_xref="GeneID:309591"
                     /db_xref="RGD:1303115"
                     /translation="MAETSLLEAGASAASTAAALENLQVEASCSVCLEYLKEPVIIEC
                     GHNFCKACITRWWEDLERDFPCPVCRKTSRYRSLRPNRQLGSMVEIAKQLQTVKRKIR
                     DESLCSQHHEPLSLFCYEDQEAVCLICAISHTHRAHTVVPMDDATQEYKEKLQKCLEP
                     LEQKLQEITCCKASEERKPGELKRLVESRRQQILKEFEELHRRLDEEQQTLLSRLEEE
                     EQDILQRLRENAAHLGDRRRDLAHLAAEVEGKCLQSGFEMLKDVKSTLEKCEKVKTME
                     VTSVSIELEKNFSHFPRQYFALRKILKQLIADVTLDPETAHPNLVLSEDRKSVKFVET
                     RLRDLPDTPQRFTFYPCVLATEGFTSGRHYWEVEVGDKTHWAVGVCRDSVSRKGELTP
                     LPETGYWRVRLWNGDKYAATTTPFTPLHIKVKPKRVGIFLDYEAGTLSFYNVTDRSHI
                     YTFTDTFTEKLWPLFYPGIRAGRKNAAPLTIRPPTDWE"
     exon            571..666
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /inference="alignment:Splign:2.1.0"
     exon            667..897
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /inference="alignment:Splign:2.1.0"
     exon            898..920
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /inference="alignment:Splign:2.1.0"
     exon            921..1036
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /inference="alignment:Splign:2.1.0"
     exon            1037..2904
                     /gene="Trim39"
                     /gene_synonym="Rnf23"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggatagggcg cacctcggtc cacagccaag ataacttacc tactaccgct tcaccgtaag
       61 ctaaatgcta aaccttagcc agtcggaagt gacgtgcaac acggcctctc agttataatg
      121 gcagagacaa gtctgttaga ggctggagcc tctgcagcct ccacagccgc tgctctggag
      181 aacttgcagg tagaggcaag ctgttctgtg tgcctggagt acctgaagga gccggttatc
      241 attgaatgtg ggcacaactt ctgcaaagcg tgtattaccc gctggtggga ggacctagag
      301 cgggacttcc cttgccctgt ctgtcggaag acatcccgat accggagcct caggcctaac
      361 cgacagctag gcagcatggt ggaaatagcc aagcagctcc agacggtcaa gcggaagatc
      421 agagacgaaa gcctctgctc ccagcaccat gaacccctta gccttttctg ctacgaagac
      481 caggaggctg tctgtctgat atgtgcaatt tcccataccc accgggccca tacggtcgtg
      541 ccgatggacg atgctacaca ggagtacaag gagaaacttc agaagtgcct ggagcccctg
      601 gaacagaagc tgcaggagat cacctgctgc aaagcctcag aagaaaggaa accaggggaa
      661 ctcaagagac tggtagagag ccgccggcag cagatcctaa aggagtttga ggagctgcac
      721 aggcgactgg acgaggaaca gcagacgctg ctctcccggc tggaggagga agaacaggac
      781 attctacaga gacttcgaga aaacgctgct caccttgggg ataggcgccg ggaccttgcc
      841 cacttagctg ctgaggtgga gggcaagtgc ttacagtcag gcttcgagat gcttaaggat
      901 gtgaaaagta ccctagaaaa atgtgagaag gtgaagacca tggaggtgac ttcagtatct
      961 atagagctgg aaaagaactt cagccatttc ccccggcagt actttgccct aaggaaaatt
     1021 cttaaacagc taattgcgga tgtgaccctg gaccctgaga cggctcatcc taaccttgtc
     1081 ctgtcagagg atcggaaaag tgtcaagttt gtggagacaa gactccgaga cctccctgac
     1141 acaccacagc gtttcacttt ctacccttgt gtcttagcta ctgaaggctt cacctcaggt
     1201 cgacactact gggaggtgga ggtgggtgac aagacccact gggcagtagg agtatgccgg
     1261 gactctgtga gcaggaaggg tgaactgact ccactcccgg agactggcta ctggcgtgtt
     1321 cggctgtgga atggggacaa gtatgcagcc accaccacgc cttttacccc tttgcacatc
     1381 aaggtgaaac ctaagcgggt aggcatattc ctagactatg aggctggcac actgtctttt
     1441 tacaacgtca cagaccgctc acatatctac accttcactg atactttcac tgaaaaactt
     1501 tggcccctct tctacccagg gatccgagcc ggtcggaaga atgctgcacc acttaccatc
     1561 agacccccaa cggattggga atgacaagag atgcagttga attggggtga ggcagggtca
     1621 agagcagcgg gccttcctaa ctggcccact ggaaaacctt ggtgtctgcg tggttccagt
     1681 cttgagccat cttgagaaac cacctcgtct gtgggatggt ttgtgtgaag gagaaagata
     1741 ggactgggct gcatgaccaa gcacagatgt gtctccctcc taactagtgg gagtgtggac
     1801 tcccagggtc caggtttcct agtgcacaag gacaggttga gaaagaaaag gcttttccag
     1861 aaaccaagtc tattggaaag ggtcttaatt tgcttaaaat gcagggaaca gaaaccttta
     1921 aaaggcttct atgactcaga atagccttgt tcttgtggaa gtgcgtaggg atctgtacac
     1981 atacctctgt gtggaagatg agtggcagtg gctgtcatga gtctaggagt tgaggggctt
     2041 ttctgggggc agagattgag cattaaagtt aggagaggaa tcagggaaaa ggctgaagga
     2101 gtgtttctag aaatgaatga agggaacggg gatttctttg atctcttttc ttagggtaat
     2161 gttaatcatt acccttagga ttagccagag gttcagatct gggagaagga aagggtggga
     2221 agaaaggaga atccgtgtcc caaaggcttg ggttattcct ggttcctgca gttggctgtc
     2281 tctaaaaagt aggctcctct cgttcccttc taaaggtgag atggaagcga ttctgcaaga
     2341 cacacatctg cccttccatt gttcccaagg caacttggag aggagtcaga tgttaaagga
     2401 gacagaacgg tgtagccaaa gctctggcct taaagaatgt tactaagttg tccaccttgt
     2461 cccctggctc aaatgtctaa ggaaagaagg gaagataatg gagtcttcct caccccacga
     2521 cagcagggta gaagagggtg gtttgtgtta caaagggcca gatgacggct aagcctctgt
     2581 ttccatcctc caccctttga cattcccctt ttcagagaat gtaaattatc ttaattttag
     2641 gccaaaataa acgacccata gggtacatat tttgtcacaa aaggtaacgt gatgcatgcc
     2701 aaaccaaaca gcctggatta tctgctgcct gggtaatctt cacacaagac tgagacaaga
     2761 aactgcattg agggtattca gttcctccta ccacctcaac aggactttgt ccactctcct
     2821 cttacctttg tgccttgact gtggttcttt gtggcaagat aatttggttg gtgaaaatat
     2881 ggaacaaagg atccactaat gtga
//
