LOCUS       NM_001106147            2627 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 36 (Trim36), mRNA.
ACCESSION   NM_001106147 XM_001053970 XM_225947
VERSION     NM_001106147.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2627)
  AUTHORS   Singh,N., Kumble Bhat,V., Tiwari,A., Kodaganur,S.G.,
            Tontanahal,S.J., Sarda,A., Malini,K.V. and Kumar,A.
  TITLE     A homozygous mutation in TRIM36 causes autosomal recessive
            anencephaly in an Indian family
  JOURNAL   Hum Mol Genet 26 (6), 1104-1114 (2017)
   PUBMED   28087737
REFERENCE   2  (bases 1 to 2627)
  AUTHORS   Ebstein,F., Lange,N., Urban,S., Seifert,U., Kruger,E. and
            Kloetzel,P.M.
  TITLE     Maturation of human dendritic cells is accompanied by functional
            remodelling of the ubiquitin-proteasome system
  JOURNAL   Int J Biochem Cell Biol 41 (5), 1205-1215 (2009)
   PUBMED   19028597
REFERENCE   3  (bases 1 to 2627)
  AUTHORS   Miyajima,N., Maruyama,S., Nonomura,K. and Hatakeyama,S.
  TITLE     TRIM36 interacts with the kinetochore protein CENP-H and delays
            cell cycle progression
  JOURNAL   Biochem Biophys Res Commun 381 (3), 383-387 (2009)
   PUBMED   19232519
REFERENCE   4  (bases 1 to 2627)
  AUTHORS   Kitamura,K., Tanaka,H. and Nishimune,Y.
  TITLE     Haprin, a novel haploid germ cell-specific RING finger protein
            involved in the acrosome reaction
  JOURNAL   J Biol Chem 278 (45), 44417-44423 (2003)
   PUBMED   12917430
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473971.1.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_225947.4, XM_001053970.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2627
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="18"
                     /map="18q11"
     gene            1..2627
                     /gene="Trim36"
                     /note="tripartite motif-containing 36"
                     /db_xref="GeneID:291597"
                     /db_xref="RGD:1308714"
     exon            1..100
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     CDS             38..2227
                     /gene="Trim36"
                     /EC_number="2.3.2.27"
                     /note="tripartite motif protein 36"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM36"
                     /protein_id="NP_001099617.1"
                     /db_xref="GeneID:291597"
                     /db_xref="RGD:1308714"
                     /translation="MSESGEMSEFGYIMELLAKGKVTIKNIEKELICPACKELFTHPL
                     ILPCQHSVCHKCVKELLLSLDDSFNDVASDSSNQSSPRLRLTSPSMDKIDKINRPGWK
                     RNSLTPRPTMFPCPGCEHDVDLGERGVSGLFRNFTLETIVERYRQAARAATAIMCDLC
                     KPPPQESTKSCMDCSASYCNECFKIYHPWGTVKAQHEYVGPTTNFRPKILMCPEHETE
                     RINMYCELCRRPVCHLCKLGGNHSNHRVTTMSSAYKTLKEKLSKDIDFLIGKESQVKS
                     QISELNLLMKETECNGERAKEEALAHFEKLFEILEDRKSSVLKAIDASKKLRLDKFHT
                     QMEEYQGLLENNGLVGYAQEVLKETDQSCFVQTAKQLHLRIQKATESLKSFRPAAQAS
                     FEDYVVNISKQTEVLGELSFFSSGIDIPEINEEQSKVYNNALIDWHHPEKDKADSYVL
                     EYRKINRDEEMISWNEIEVHGTSKVVSNLESNSPYAFRVRAYRGSICSPCSRELVLHT
                     PPAPVFSFLFDEKCGYNTEHLLLNLKRDRVESRAGFNVLLAAERIQVGHYTSLDYIIG
                     DVGITKGKHFWACRVEPYSYLVKVGVASSDKLQEWLRSPRDAASPRYEQDSGHDSGSE
                     DAYFDSSQPFTLVTIGMKKFFIPKSPTSSNEPENRVLPMPTSIGIFLDCDKGKVSFYD
                     MDHMKCLYERQVDCSHTMYPAFALMGSGGIQLEETITAKYLEYEEDV"
     exon            101..335
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     exon            336..661
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     exon            662..808
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     exon            809..904
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     exon            905..1158
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     exon            1159..1283
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1574
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     exon            1575..1872
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
     exon            1873..2627
                     /gene="Trim36"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggtctggctg gtccatagtt cataaagggt cttgaccatg tcggagtcag gggagatgag
       61 tgaatttggc tacattatgg aattgcttgc caagggcaag gtgactatca agaatatcga
      121 aaaggagctt atttgcccag catgcaagga gctgtttaca cacccgctga tccttccctg
      181 ccagcacagc gtctgtcata aatgtgtgaa agaactctta ctgtctcttg atgactcatt
      241 caacgatgtg gcgtcagaca gctctaatca gagcagccct cggctccggc tcacctcccc
      301 cagcatggat aaaatcgaca agattaacag accaggctgg aagcgtaatt cactgacccc
      361 cagaccaacc atgtttcctt gtcctggctg cgagcatgat gtggatcttg gagagcgagg
      421 agtcagtggt ctgtttcgaa atttcacttt ggaaacgatt gtcgagaggt accggcaggc
      481 tgctagggca gccacagcca ttatgtgtga cctttgtaaa ccaccacccc aggaatctac
      541 aaagagctgc atggattgta gtgcaagcta ctgcaacgaa tgcttcaaaa tttatcatcc
      601 ctggggcacg gtaaaagccc agcatgagta tgtgggcccc accactaatt tcagacccaa
      661 gattttaatg tgcccagaac atgagacaga gagaataaac atgtactgtg aactgtgcag
      721 gagaccggtt tgccacctct gtaagttggg tgggaatcat tccaatcacc gggtaaccac
      781 catgagcagt gcctacaaaa cattaaagga gaaactttca aaagacattg atttccttat
      841 tggtaaggaa agccaggtga agagtcaaat ttctgaacta aacttgttaa tgaaagaaac
      901 agagtgcaat ggagagaggg cgaaggaaga agcgctggca cattttgaga agctctttga
      961 aatcctggaa gacaggaagt cgtctgttct gaaagccata gatgcctcta agaaactaag
     1021 actagataaa tttcacactc aaatggaaga gtaccaaggc cttctagaga ataacgggct
     1081 tgtgggatat gctcaggaag tgctgaagga gacggatcag tcttgctttg tgcagacagc
     1141 aaagcagctc catctcagaa tacagaaagc tacagaatcc ctgaagagct ttagacctgc
     1201 agcccaggct tcttttgaag actatgttgt taacatttcg aaacaaacag aggtgcttgg
     1261 agaattgtcc tttttctcta gtggcataga cattcctgag atcaacgagg aacagagtaa
     1321 agtgtataat aatgccctga tagactggca ccatccagaa aaggacaaag ccgacagcta
     1381 tgttctcgaa taccgcaaga ttaatagaga cgaagaaatg atatcctgga atgagataga
     1441 agttcatggc acaagtaaag ttgtctccaa tcttgaaagc aacagtccct atgcgttccg
     1501 agtgagagct tacaggggtt ctatctgcag tccctgcagt cgagaactgg ttctgcatac
     1561 tcctccagct ccagttttca gtttcctgtt tgatgaaaag tgtggctaca atactgagca
     1621 tctcttgctg aacctgaaga gagaccgggt agaaagcaga gctggattta atgtcctcct
     1681 cgctgcggaa cgcatccaag tgggccatta cacaagctta gactacatca tcggggatgt
     1741 cggaatcacg aaaggtaaac acttctgggc ctgccgtgtg gaaccgtatt catacctggt
     1801 gaaagtggga gttgcttcca gtgacaaact gcaagagtgg ctgcgctctc cccgggacgc
     1861 agctagtcca agatatgagc aagacagtgg gcatgacagc ggaagtgagg acgcctattt
     1921 tgattcttca caaccgttta cattagttac tataggcatg aagaaatttt ttatacccaa
     1981 gtcacctact tcttctaatg aacccgaaaa cagagttctc cccatgccaa caagtatagg
     2041 gattttcctt gactgtgata aaggcaaagt gagcttctat gatatggacc acatgaaatg
     2101 cctatatgag cgccaggtgg actgttcaca cacaatgtac cccgcttttg cgttaatggg
     2161 cagtggcggg atccagcttg aggaaaccat caccgcgaag tatctggaat atgaagagga
     2221 tgtgtagctt ggacacccca caggacgagg atcagaactg tgaacaaagc catgccgtgg
     2281 tgttagagtc ttcgtaacta attacatatc atttacgtct ctgtcaccac acctgtttgt
     2341 actgtgtgat tctttgtttt gttttgttct gctttgacac acacagtctc agtgtgtagt
     2401 ccaggccagc ttcaaactct gttctgttat agcctcctta ggggctggga ttataggcag
     2461 gcaccaccat acccagctag tgtatgattc acaacttttt tcatgtcata atggtcttac
     2521 cttttacaaa tggtgggagt agagacttgt cttaactggt ccaggataga taactctaca
     2581 atggaagtcc ttctctttgg ggacaaggac tctaattgat gtaagtc
//
