LOCUS       NM_001025142            3701 bp    mRNA    linear   ROD 30-JUL-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 35 (Trim35), mRNA.
ACCESSION   NM_001025142 XM_573809
VERSION     NM_001025142.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3701)
  AUTHORS   Uchil,P.D., Quinlan,B.D., Chan,W.T., Luna,J.M. and Mothes,W.
  TITLE     TRIM E3 ligases interfere with early and late stages of the
            retroviral life cycle
  JOURNAL   PLoS Pathog 4 (2), e16 (2008)
   PUBMED   18248090
REFERENCE   2  (bases 1 to 3701)
  AUTHORS   Lalonde,J.P., Lim,R., Ingley,E., Tilbrook,P.A., Thompson,M.J.,
            McCulloch,R., Beaumont,J.G., Wicking,C., Eyre,H.J.,
            Sutherland,G.R., Howe,K., Solomon,E., Williams,J.H. and
            Klinken,S.P.
  TITLE     HLS5, a novel RBCC (ring finger, B box, coiled-coil) family member
            isolated from a hemopoietic lineage switch, is a candidate tumor
            suppressor
  JOURNAL   J Biol Chem 279 (9), 8181-8189 (2004)
   PUBMED   14662771
REFERENCE   3  (bases 1 to 3701)
  AUTHORS   Kimura,F., Suzu,S., Nakamura,Y., Nakata,Y., Yamada,M., Kuwada,N.,
            Matsumura,T., Yamashita,T., Ikeda,T., Sato,K. and Motoyoshi,K.
  TITLE     Cloning and characterization of a novel RING-B-box-coiled-coil
            protein with apoptotic function
  JOURNAL   J Biol Chem 278 (27), 25046-25054 (2003)
   PUBMED   12692137
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CB743135.1 and
            BC085942.1.
            
            On Mar 16, 2007 this sequence version replaced NM_001025142.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ224662.1, FQ094961.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-37                CB743135.1         64-100
            38-3701             BC085942.1         1-3664
FEATURES             Location/Qualifiers
     source          1..3701
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="15"
                     /map="15p12"
     gene            1..3701
                     /gene="Trim35"
                     /note="tripartite motif-containing 35"
                     /db_xref="GeneID:498538"
                     /db_xref="RGD:1564642"
     exon            1..484
                     /gene="Trim35"
                     /inference="alignment:Splign:2.1.0"
     CDS             8..1555
                     /gene="Trim35"
                     /EC_number="2.3.2.27"
                     /note="tripartite motif-containing protein 35; tripartite
                     motif protein 35"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRIM35"
                     /protein_id="NP_001020313.2"
                     /db_xref="GeneID:498538"
                     /db_xref="RGD:1564642"
                     /translation="MKAAASVVTAAAPAMEPGPSVSPGPSRSFKEELLCAVCYDPFRD
                     AVTLRCGHNFCRRCVSGCWEVQTTPSCPVCKERAVPGELRTNHTLNNLVETLLREEAE
                     GARWTGRRSPRPCRAHRAPLTLFCVEDKELLCCACQADARHQEHRVQPIKDTAQDFRA
                     KCKNMEHVLREKAKSFWALRRTYEAIAKHNEVQTTWLEGRIRDEFDKLRDFLRVEEQA
                     TVDAMKEESRKKHLLAEEKMKQLAEQTEALAREIERLQMEMKEDDMTFLMKHKSRKRR
                     LFCTVEPAPLQPGLLMDACKYLESLQYRVWKKMLGSVESVPFSLDPNTAAGWLKVADD
                     LTSVINHGYRVQVENPERFSSAPCLLGSQVFSKGSHSWEVDVGGLPSWRVGVVRVQAH
                     AQAQAQADVGGEGHSHSCYHDTRSGFWYLCRTQGVDGDHCMTSDTATAPLVQAMPRRL
                     RVELECEEGELSFYDSERHCHLYTFHAHFGEVRPYFYLGASRGDGPPEPLRICHLRVS
                     IKEELDI"
     exon            485..580
                     /gene="Trim35"
                     /inference="alignment:Splign:2.1.0"
     exon            581..811
                     /gene="Trim35"
                     /inference="alignment:Splign:2.1.0"
     exon            812..834
                     /gene="Trim35"
                     /inference="alignment:Splign:2.1.0"
     exon            835..953
                     /gene="Trim35"
                     /inference="alignment:Splign:2.1.0"
     exon            954..3676
                     /gene="Trim35"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gctaggcatg aaggcggctg catcggtggt gacggctgct gctcctgcga tggagccagg
       61 cccctctgtg tcccccgggc cttcgcgctc cttcaaagag gagctgctgt gtgccgtgtg
      121 ctacgacccg ttccgcgacg cagtgactct gcgctgtggc cacaacttct gccgccggtg
      181 cgtgagcggc tgctgggagg tgcagacgac gccctcgtgc ccggtgtgca aggaacgagc
      241 ggtgcccggg gagctgcgca ccaaccacac gctcaacaac ctggtggaga ccttgctgcg
      301 cgaggaggcc gagggcgcgc gctggaccgg tcgccggtcc ccgcgcccct gccgcgcgca
      361 ccgtgccccg ctcacgctct tctgcgtgga ggacaaggag ctgttgtgct gtgcctgtca
      421 agccgacgcc cggcaccagg agcatcgtgt gcaacccatc aaggacactg cgcaggactt
      481 ccgggccaag tgtaagaaca tggagcacgt acttcgggag aaagccaagt ccttctgggc
      541 tctgaggcgc acctatgagg ccattgccaa gcacaatgag gtgcagacaa cttggctaga
      601 aggccgaatc cgggatgagt ttgacaagct ccgagatttc ctgagggtgg aggaacaagc
      661 caccgtggat gccatgaagg aagagagcag gaagaagcac ctgctggctg aggagaagat
      721 gaagcagctg gcggagcaga ccgaggcact ggctcgagag attgagcgtc tgcagatgga
      781 gatgaaggaa gacgacatga ccttcctcat gaaacacaag agccgaaaac gccggctctt
      841 ctgcaccgtg gagccagcac ctctccagcc tggcttgctt atggacgcat gcaagtatct
      901 ggagtccttg cagtaccgag tctggaagaa gatgcttggg tctgttgaat cggtgccctt
      961 cagcttggat cccaacacag ctgctggctg gctcaaagtg gctgatgacc tcacgagcgt
     1021 catcaaccat ggctaccgtg tgcaggtgga gaatccagag cgcttctcct cggcaccctg
     1081 cctgctgggc tctcaagttt tctccaaggg ctcccactct tgggaggtgg atgtgggtgg
     1141 cctgccgagc tggcgagtgg gcgtggtgcg ggtgcaggca catgcacagg cacaggctca
     1201 ggctgatgtc ggtggtgagg gccactcaca cagctgttac catgatacac gctcaggctt
     1261 ctggtacctg tgccgcactc agggtgtgga cggagaccac tgcatgactt ccgacacagc
     1321 cacagcccct ctggtccagg ccatgccacg ccgtctgcgt gtggagctgg agtgtgagga
     1381 gggtgagctg tccttctatg actctgagcg ccactgccat ctgtatacct tccatgccca
     1441 ctttggggag gtgaggccct acttctacct aggggcctct cggggtgatg gtcccccaga
     1501 acctctgcgc atctgccacc tgcgtgtctc catcaaagaa gagctggaca tctgagctgc
     1561 gggagttggt agcccaccac tgacactcgt gcagcatcac gccttttctt agttccaagt
     1621 ccgcctatgc ctctgtcttt atttttagtc ctttttctgc ccaaagttaa gagcccccca
     1681 ggaggtgctt ggctgagctt aggctctgtg gaatcatgct accttcagga tgtgggcttc
     1741 atttcctctg tccttgcatt gctggtatac tgttttcttg aaggaaggca ttataatgca
     1801 ggtgtgacta ttttgagtct gtcatttatg tttctaggaa aaggtccttg tcaggccata
     1861 cggggaagcc ccaggattgg ttgatccaag agtgggcaaa gccttcacct aggctctccc
     1921 atctcagtag ggcaagttag gcattgtcag cctaagtgag caaacatggc tcactttggc
     1981 atctggtctg aagcttgaga gttcccctgt tggccccaca cagactgggg tgattaggac
     2041 aggatttctc tgggaactcg gggtgcaagg tactctggaa tacagctcag agttagtggg
     2101 tgtcacagga aaggcaactc tggagccagc ttcaagtcag tgacacagag gccatagtac
     2161 cagaatgcag tgagaagaca gctggtgctg ggctgggacc agagccctgc tctgctgctc
     2221 ttttgagcta acttcctgtc ggcatggaat caacattgat tggtcaactc atgctttgaa
     2281 agttctctga aactttgtcc agttttctag aacactttta aaaaattaac ttgtttgtcc
     2341 tctttctctc ttggggcctg tgtttccaca tctatgaatt gacagtagtc cttggaagtc
     2401 agtggaggaa ggtatgagga ggggcctcag tggatgctgc ttcagtcagg aactgttggt
     2461 ctgggaggcc agtcctgtcc ttgatgccct tgtcttcatt ggcttcagcc attgttcttg
     2521 ctctgctctg tgcagatttc acttttcctt gtgtgcccct ccaccttttc tttctcactc
     2581 atgcctatag atggagtcta attgccagct aaccaaatcc caagttgtgt cttaaggaga
     2641 aatagcacct caggggtgca ccgtcatagt caggaacaca ttgctgacct aggacctagc
     2701 atcccaattt cagcctgcac ccctcattac ataagacttg ttttaaacca tgccgcttac
     2761 ccactaattg gctctaacta ggtcatgcgc attgattatc taacaagtgg ggacacagaa
     2821 gaacccctgg tgcaggccag gctgggagca gggacagtgt tggcaagcca gcttatgagt
     2881 gtcagatgct tgggcaccac gggtgtgaaa aggtatgcct gctatgatgt atgtgtccag
     2941 tttctctaaa gaaactctcc ctgaagttac tcttaatttt aattttcacc ttagttcttt
     3001 ttaaataggg taattttaat gacctagaat cttttagaaa gattttactt gacccacaac
     3061 tgacatgttt ctttcagagc ctttgtaaac acaaattctt tctgtaactt gtacctgact
     3121 cgatccttcc cattgtaaga ctatcgtgtg cagtgaatgt gctgtgtagt ttgttagttg
     3181 gtggacattt cgcttgttgc agtgtttagc tattatgagt tctgctatga aatttgtgtg
     3241 caagttttgt gtggatgtgt ctcttttgat tctctgtcat ataccttgga gtctgttttc
     3301 caggtcatat gataattatt ttaaaccctt tggggacttg ccacgctgtt tgtaagagaa
     3361 ccgttccatt ttctactccg gccggcagca ggtgagggct gggttgtagc gagttcttgt
     3421 cagcactgtc tgccctctca gctagccgta ctgaggaaac tggagtgtgt ctcatctgac
     3481 ctgcagttgc catccttgac ggctgacgag ggagcatctt ttctcatgtt tgctgtgtat
     3541 ctgcttcaga gacttaagag tgtttgcccc tcaggttgtc cgtctttcta ttatgaagtt
     3601 ttacaagttt gttaatgcat tctagataaa agttcctttg tgtcagatga gtcacttata
     3661 aaaattttcc tcctaaaaaa aaaaaaaaaa aaaaaaaaaa a
//
