LOCUS       NM_001291382            3829 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus tripartite motif containing 15 (Trim15), mRNA.
ACCESSION   NM_001291382
VERSION     NM_001291382.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3829)
  AUTHORS   Uchil PD, Hinz A, Siegel S, Coenen-Stass A, Pertel T, Luban J and
            Mothes W.
  TITLE     TRIM protein-mediated regulation of inflammatory and innate immune
            signaling and its association with antiretroviral activity
  JOURNAL   J Virol 87 (1), 257-272 (2013)
   PUBMED   23077300
REFERENCE   2  (bases 1 to 3829)
  AUTHORS   Uchil PD, Quinlan BD, Chan WT, Luna JM and Mothes W.
  TITLE     TRIM E3 ligases interfere with early and late stages of the
            retroviral life cycle
  JOURNAL   PLoS Pathog 4 (2), e16 (2008)
   PUBMED   18248090
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JACYVU010000320.1.
            
            [WARNING] On Apr 3, 2024 this sequence was replaced by
            NM_001291382.3.
            
            On Feb 10, 2021 this sequence version replaced NM_001291382.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the exon
            combination of this transcript record were based on alignment of
            mouse ortholog, NM_001177872.1, and RNASeq data.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06680412,
                              SAMN06680413 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            inferred exon combination :: based on alignments, homology
            RefSeq Select criteria    :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-893               JACYVU010000320.1  1700905-1701797
            894-989             JACYVU010000320.1  1702126-1702221
            990-1220            JACYVU010000320.1  1703978-1704208
            1221-1243           JACYVU010000320.1  1704823-1704845
            1244-1359           JACYVU010000320.1  1706402-1706517
            1360-1392           JACYVU010000320.1  1706934-1706966
            1393-3829           JACYVU010000320.1  1707813-1710249
FEATURES             Location/Qualifiers
     source          1..3829
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..3829
                     /gene="Trim15"
                     /note="tripartite motif containing 15"
                     /db_xref="GeneID:100910806"
                     /db_xref="RGD:6496746"
     exon            1..893
                     /gene="Trim15"
                     /inference="alignment:Splign:2.1.0"
     CDS             528..1406
                     /gene="Trim15"
                     /note="tripartite motif-containing protein 15-like"
                     /codon_start=1
                     /product="tripartite motif-containing protein 15"
                     /protein_id="NP_001278311.1"
                     /db_xref="GeneID:100910806"
                     /db_xref="RGD:6496746"
                     /translation="MPLTRSLRGPHQVACTVCTRPLQDAVTIACGHAVCLLCLPRAPM
                     GAQLLCPLCQGAEEEKIQTAVTPVSLGPLSETCCEEHGEKIYFFCKTDAELLCVFCRE
                     GPAHQAHTVGFLDEAIQPYRDRLRSRLEALRMERDKIEDRKCQEDQKLQEVLMQVESK
                     KQQVEAAFERLKRELVDQRCLLLTRLEELEQQIWKEREEYITTVSQEVDRLGAQVEEL
                     EEKCQQPASELLQDARLNQSRYEMKTFVCPEAISSDLIKKIRNLHRKILCLPKMMRTF
                     SENLMHHLETDSETEA"
     exon            894..989
                     /gene="Trim15"
                     /inference="alignment:Splign:2.1.0"
     exon            990..1220
                     /gene="Trim15"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1243
                     /gene="Trim15"
                     /inference="alignment:Splign:2.1.0"
     exon            1244..1359
                     /gene="Trim15"
                     /inference="alignment:Splign:2.1.0"
     exon            1360..1392
                     /gene="Trim15"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..3829
                     /gene="Trim15"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcggcaggg gaggtaggcg agtaaagaaa ggtcagagga gaggaacgtg catttgggca
       61 gtctcaacgc cacttgctgg actttgatgc tactgcgggc ctcctagctc tacggctctc
      121 acctgctcag cctgacagga agcggctcct ccccaacggt cccacccctc tgtagccaag
      181 agattccagg aaaccccatt tccaagtgac ctcatgatgc aatacgctgc tccccaccca
      241 aggaacggaa ggcgacagga gtggagagct aggtcacctg cagccactgg gaaacgctgg
      301 gtagtcaaga cgccctggag tttggacctg ctttgctgct gggttctggg cgtggctcag
      361 gcgcagccag gtgacctcgg tgagctgaca ttcctgcctt tctttcagcc tcggattcct
      421 ttgcttctgt gacagtgacg cacttaaaag tgactcagtt tcagggaaag gaaattggtg
      481 tggagagaga cagaagactg cgtggacagg cagaggaagg cacggtgatg cccttaaccc
      541 ggtccctgcg gggaccccac caagtagcct gtactgtctg cacccggccc ctgcaggatg
      601 cggtgaccat agcctgtgga cacgctgtct gcctactctg cctcccgcgc gccccaatgg
      661 gggcccagct gctgtgcccg ctctgtcagg gggcagaaga ggagaaaatc cagaccgcag
      721 tgactccggt atccctaggt cccctgagcg agacctgctg cgaagagcac ggagagaaga
      781 tctatttctt ctgcaagaca gacgcggagc tgctctgcgt gttctgcagg gagggccccg
      841 cccaccaggc acacactgtg gggttcctgg atgaagccat ccaaccctac agggatcgtc
      901 tcaggagtcg gttagaagct ctaagaatgg agagggacaa gattgaagat aggaaatgtc
      961 aagaagacca gaagctccag gaggttctga tgcaggttga aagcaagaag caacaggtag
     1021 aagctgcttt cgaaaggctg aagcgggagc tggtggacca gaggtgcctc ctgttgacca
     1081 ggctggagga actagaacag cagatctgga aggagaggga ggagtacatc acgacggtct
     1141 cccaggaggt cgaccggctg ggtgcccagg ttgaggagtt agaggagaaa tgtcagcaac
     1201 cagcaagtga gcttctgcaa gatgccagac tcaaccagag caggtatgag atgaagactt
     1261 ttgtgtgccc agaggccatt tcctctgacc tcatcaaaaa gattagaaac ctccacagga
     1321 aaatactctg cctcccaaag atgatgagga cattctcaga aaacttgatg caccatctgg
     1381 aaacagattc agaaacagaa gcctaggaag caggcagcaa tggactatgt gtcatcctga
     1441 agtgagggta gggggtcact ctggatcctc agaccaaaac ccggagccca atcctctctg
     1501 taatggccac ccgagtggca gctgcaccgt aagagtggcc ccaaggtgag gggatggcag
     1561 gacctgggca ctgaggacag tgtcctcgct gtgacacttt tccaactggc tagcacccat
     1621 ctgccacgca aatggagaca cacctgttct ttgcggcgta gacgtggtca cagactacca
     1681 ggtatgggag agatcctgca aacgtcaaat accaaggcac caaccgccat ctttttccaa
     1741 ccctgtccca cctggacaaa gttcctgccg gccgtagaaa gactgaagtg gaggcagtga
     1801 attgtggcag acaagacagc agccggaaac ccagctctgt gcctagcatt caaaaatgag
     1861 gttggaactt agggtcttgg agtcttgtac agtttttaat gtgttaatcc agtactgtca
     1921 gcaccctgca atcccgttcc tggacacggt gatctctctg gagagccaga agcagacaag
     1981 gaaggcattg ctctagacac caagcaaagc tataagccaa tgggatttaa caaagtaact
     2041 gtaaaagttt caaaatgacc attgtagggt aaccagggct gtttggcttg tactaattta
     2101 taatgacttt tggacacaaa gctggagatg ctttggggcc tcaacaaatc tgggtggacc
     2161 ccaaagtgtc ccttcaggtc atttctctag gttttaagag aatgttttaa taaaataagc
     2221 caagggcctt gtgttttgtg tctaatctgt tgattgtggc aacttagaaa gatggggttg
     2281 gggtgattct agtttcaatc ttctgaatgg tgaggtgtta aaggactggc cggaagagtg
     2341 gactaattag gaggtagtgt ctttaggtca ctagggtagc tttggaagga gactctcagg
     2401 gtctggttca ttctgtttcc cagctgatga gatgtgtgac tgtgctctgt caagcaagcc
     2461 tgccaggatt ggttaccatg acagaggcca aaagcactga gaccactgat catggactgc
     2521 aacttcagaa ccaggagctt aaataaacct tttttctagg ttgccccggg tattttaaag
     2581 gtttttaccc ctccttagtg tgacagtata aggctttaaa tctcgccatg tgagcctgag
     2641 gccagccatg tctacatcgt gagattcatg tccagctcct caattgtatg tatgtattat
     2701 gtatgtgtgt ggttcatatg tgttagaaca aggagtaagg atacaagtaa gactcccaga
     2761 ctcttctgta aaacagaaac aggccacaga gagatatcat gaggcaaaga gccccacggg
     2821 aattctgaaa atcaggagct taaggcagta gagcaatcct gacatcctaa aagaaaacta
     2881 cttttgaaga ataccttaag tgtacaagtg agataaacat ttcccaatgt ttgaaaatgc
     2941 agcttccaaa ctcatctcag aagtttttaa atgatgtgtg acagaaccac agttaagtta
     3001 ggagaggaga cacagggtcc agaaatagga ccagggcttg ggatgccacc tggggagtgc
     3061 ttgcccagga tgcgagagac cctgggttca gtccccagca cttaaaccag gcattagtgg
     3121 cacccacctg aaatctcaga ccttagaagg cgagacagga agtttaaggt catcttcagc
     3181 tacacaagac ttaggctagc tgggctacag gcctcagagg gaaaagatcc agaaccccca
     3241 gtttaatgac aaaaggggat ttaaaaagct gtccgcagag ggaacaatca atggctcagg
     3301 ttcaagttca ttccggtagg caccaagata agaggaggag acagccccag acgactgtct
     3361 tttgagattt ctgaccactg agaagaacgt gtagtttatt cagtaaccaa gacacaggaa
     3421 atgaagggag ggagagatga ttagctctag gaacaaagag tggtgaggga gccactgtgt
     3481 gtgtaactag tgactcaggc agcatgtgag gcctacggag tgctctgtct cgagacggtg
     3541 tggggtgtgg cttactctga ggccactgag atccagcatc tgggaacagt ctgtcaggag
     3601 ccaagaggag ctaacacttg cacaggctga agaaatctgg aatgtttaag gattaaaggg
     3661 ggggggggcg catcattttg gctaagcagg agctcgggtt caactgtggg caccagctag
     3721 gtcagcaagg agataatgca ggccttttct tcataggaag acctagggca gaggtcctct
     3781 atattcctca tggcccgctc tccccttctg caatccctct cttaggaaa
//
