LOCUS       NM_001009176            2366 bp    mRNA    linear   ROD 26-FEB-2024
DEFINITION  Rattus norvegicus tripartite motif-containing 10 (Trim10), mRNA.
ACCESSION   NM_001009176
VERSION     NM_001009176.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2366)
  AUTHORS   Yang H, Wang XX, Zhou CY, Xiao X, Tian C, Li HH, Yin CL and Wang
            HX.
  TITLE     Tripartite motif 10 regulates cardiac hypertrophy by targeting the
            PTEN/AKT pathway
  JOURNAL   J Cell Mol Med 24 (11), 6233-6241 (2020)
   PUBMED   32343488
  REMARK    GeneRIF: Tripartite motif 10 regulates cardiac hypertrophy by
            targeting the PTEN/AKT pathway.
REFERENCE   2  (bases 1 to 2366)
  AUTHORS   Huang Q, Zhu X and Xu M.
  TITLE     Silencing of TRIM10 alleviates apoptosis in cellular model of
            Parkinson's disease
  JOURNAL   Biochem Biophys Res Commun 518 (3), 451-458 (2019)
   PUBMED   31472958
  REMARK    GeneRIF: Silencing of TRIM10 reduced cell apoptosis and Reactive
            Oxygen Species levels in a cellular model of Parkinson's disease,
            suggesting a potential role of TRIM10 in Parkinson's disease
            treatment.
REFERENCE   3  (bases 1 to 2366)
  AUTHORS   Uchil PD, Quinlan BD, Chan WT, Luna JM and Mothes W.
  TITLE     TRIM E3 ligases interfere with early and late stages of the
            retroviral life cycle
  JOURNAL   PLoS Pathog 4 (2), e16 (2008)
   PUBMED   18248090
REFERENCE   4  (bases 1 to 2366)
  AUTHORS   Reymond A, Meroni G, Fantozzi A, Merla G, Cairo S, Luzi L,
            Riganelli D, Zanaria E, Messali S, Cainarca S, Guffanti A, Minucci
            S, Pelicci PG and Ballabio A.
  TITLE     The tripartite motif family identifies cell compartments
  JOURNAL   EMBO J 20 (9), 2140-2151 (2001)
   PUBMED   11331580
REFERENCE   5  (bases 1 to 2366)
  AUTHORS   Harada H, Harada Y, O'Brien DP, Rice DS, Naeve CW and Downing JR.
  TITLE     HERF1, a novel hematopoiesis-specific RING finger protein, is
            required for terminal differentiation of erythroid cells
  JOURNAL   Mol Cell Biol 19 (5), 3808-3815 (1999)
   PUBMED   10207104
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC129078.1.
            
            On Jan 10, 2007 this sequence version replaced NM_001009176.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC129078.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMD00132268,
                                           SAMD00132298 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2366
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20p12"
     gene            1..2366
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /note="tripartite motif-containing 10"
                     /db_xref="GeneID:294210"
                     /db_xref="RGD:1359438"
     exon            1..786
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     CDS             358..1827
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /note="tripartite motif protein 10"
                     /codon_start=1
                     /product="tripartite motif-containing protein 10"
                     /protein_id="NP_001009176.1"
                     /db_xref="GeneID:294210"
                     /db_xref="RGD:1359438"
                     /translation="MASAPSVTSLADEVNCPICQGTLREPVTIDCGHNFCRGCLTRFC
                     ETPGPESEESLSCPLCKEPFRPGSFRPNWQLANVVENIERLQLASTRGLEVEDACPEH
                     GEKIYFFCEEDEAQLCVVCRETGQHGAHTVRFLEDAAGPYREQIQKCLVCLRKEREEI
                     QETQSRENKRIQVLLTQVATKKQQVISQFAHLSRFLERQQTVLLAQLEGLDGDILKQQ
                     EEFDSLATREICRFSTLIEELEEKNERPARGLLTDIRSTLIRCETRKGRKPEAISPGL
                     GQRIRDFPQQVMPLRQEMKIFLEKLCFELDYEPALISLDPQTSHPKLLLSEDHRKAQF
                     SYKWQNSPDTPQRFDRATCVLARCGFTEGRHTWVVNVDLAHGGSCTIGVVKEDVRRKG
                     EVRLRPEEGIWAVRLAWGFVSALGSFPTRLALEEQPRKVQVSLDYEVGWVTFVNADTQ
                     EHIYTFTAFFTQKVFPFFGLWGRGSSFSLSCQEGVVSLL"
     exon            787..882
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            883..1113
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            1114..1136
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            1137..1252
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            1253..1285
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /inference="alignment:Splign:2.1.0"
     exon            1286..2335
                     /gene="Trim10"
                     /gene_synonym="Rfb30; Rnf9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aaaggaaaga tctctttcaa cagtggactg cagagagaat acacacttat ttttatgttt
       61 tttttcctgt gagcagcttc gggtagacag aaagagacag tgagacccag gccataggaa
      121 ctggtccgga gagtgaactt atgatgctgt gagctcctgg gccctcctcc tctgctattt
      181 ctacatctcc gctgttggca ggagtgtgtc tgctcccagg agagtcgaac aaggggttct
      241 ggtgccagag atgtaactgg gccccttgtc cgagtgtgtg tgactgtact agtgttcagg
      301 actgacgtgg atgagagatg gtgacttcca ggagtcagaa ggcccagtag ggttgacatg
      361 gcctcagctc cttccgtgac tagcctggca gatgaggtca actgccccat ctgccaaggc
      421 accctaaggg aaccagtcac cattgactgt ggccacaatt tctgtcgtgg ctgcctcact
      481 cgcttctgtg agaccccagg cccagaatcg gaagagtccc tcagctgccc gctctgcaaa
      541 gagcccttcc gtccagggag cttccggcca aactggcagc tggccaatgt ggtggagaat
      601 atcgagcgcc ttcagctggc atccacaaga ggcctggagg tggaggatgc ctgtccggaa
      661 cacggggaga aaatctactt cttctgcgag gaggatgagg cacagttgtg tgtggtatgc
      721 cgcgagactg gacagcatgg ggctcacact gtgcgcttcc tggaggacgc agcaggtccc
      781 tacagggaac aaatacagaa gtgtctcgtg tgtctaagga aagagagaga ggagattcag
      841 gaaacccaat caagagaaaa caaaagaata caagtgctcc tgacgcaggt agccaccaag
      901 aagcaacagg tgatttcaca gtttgctcat ctgagccggt tcctggagcg acagcagact
      961 gtgctcttgg cacagctgga ggggttggac ggggacatcc tgaagcagca ggaagagttt
     1021 gattccctgg ccacgaggga gatctgccgg ttcagcaccc tgatcgagga gctggaggag
     1081 aagaatgagc ggccagccag ggggctcctg acggatatca gaagcactct aataagatgt
     1141 gaaaccagaa agggccggaa acctgaggct atatccccag gactgggcca aaggatccgg
     1201 gacttccccc aacaggtcat gcccctgcgg caggagatga agatatttct ggaaaaactc
     1261 tgctttgagt tggactatga gccagctctt atctctctag acccccagac ttcccacccc
     1321 aagctcctcc tctctgaaga ccatcggaag gctcagttct cctacaaatg gcagaattca
     1381 ccagatactc cacaacgctt tgatcgagcc acctgcgttc tggcccgatg tggctttaca
     1441 gaggggagac acacttgggt ggtgaatgtc gacttggccc acggaggcag ctgcactata
     1501 ggtgtggtca aagaagatgt acgaagaaag ggagaagtga ggctgaggcc agaggaggga
     1561 atatgggcag tgaggctggc ttggggcttt gtctcagctc tgggttcctt ccccacaagg
     1621 ctagccctgg aggagcaacc ccggaaggtg caggtgtctc ttgactatga ggtaggctgg
     1681 gtgacctttg tcaatgctga cacccaagaa catatctata ccttcactgc cttcttcacg
     1741 cagaaggtct ttcccttttt tggactctgg ggcagagggt ccagtttttc cctgagctgt
     1801 caggaaggtg tagtttccct cctctgagta caagactgga atcaagcacc cttgggagca
     1861 gacccttggc tgggtctcca ggctcaaacg tgaatttttt agatagttgg gatggcatgt
     1921 gttagtaagg gacaaggtag taggaccttt agtttcttca ttgttcaagc ctttccccag
     1981 tgtccatcag atgctcaggg tgtctgggac cttggctgct gcaggctggt ctcaccactg
     2041 tcatcaacgg gcacagacat ggatgtacaa acagtgctgg cttttaagcc taaagacctg
     2101 gattccagat gaagccctgt catcacccag ctgcgtgatt ttaaacaaaa ctttgcctct
     2161 tcattctgtt ttcttccaaa gatattagct aatttattca tatttcaaga aacatttgga
     2221 ggcatagatg tgatcaaaac acacacacac acacatacgc acacacatac acacacacac
     2281 catatatata tatatatgta ttatataaag gataaataaa aatgttgttt gaaaaaaaaa
     2341 aaaaaaaaaa aaaaaaaaaa aaaaaa
//
