LOCUS       NM_001106885             919 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus triggering receptor expressed on myeloid cells 1
            (Trem1), mRNA.
ACCESSION   NM_001106885 XM_001063859 XM_217336
VERSION     NM_001106885.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 919)
  AUTHORS   Sun,X.G., Zhang,M.M., Liu,S.Y., Chu,X.H., Xue,G.Q., Zhang,B.C.,
            Zhu,J.B., Godje Godje,I.S., Zhu,L.J., Hu,H.Y., Hai-Wang, Shen,Y.J.
            and Wang,G.Q.
  TITLE     Role of TREM-1 in the development of early brain injury after
            subarachnoid hemorrhage
  JOURNAL   Exp Neurol 341, 113692 (2021)
   PUBMED   33727099
  REMARK    GeneRIF: Role of TREM-1 in the development of early brain injury
            after subarachnoid hemorrhage.
REFERENCE   2  (bases 1 to 919)
  AUTHORS   Liang,Y.B., Song,P.P., Zhu,Y.H., Xu,J.M., Zhu,P.Z., Liu,R.R. and
            Zhang,Y.S.
  TITLE     TREM-1-targeting LP17 attenuates cerebral ischemia-induced neuronal
            injury by inhibiting oxidative stress and pyroptosis
  JOURNAL   Biochem Biophys Res Commun 529 (3), 554-561 (2020)
   PUBMED   32736673
  REMARK    Erratum:[Biochem Biophys Res Commun. 2023 Oct 1;675:184-186. doi:
            10.1016/j.bbrc.2023.07.016. PMID: 37516577]
REFERENCE   3  (bases 1 to 919)
  AUTHORS   Fang,K., Li,H.R., Chen,X.X., Gao,X.R., Huang,L.L., Du,A.Q.,
            Jiang,C., Li,H. and Ge,J.F.
  TITLE     Quercetin Alleviates LPS-Induced Depression-Like Behavior in Rats
            via Regulating BDNF-Related Imbalance of Copine 6 and TREM1/2 in
            the Hippocampus and PFC
  JOURNAL   Front Pharmacol 10, 1544 (2020)
   PUBMED   32009956
  REMARK    Erratum:[Front Pharmacol. 2020 Apr 15;11:518. doi:
            10.3389/fphar.2020.00518. PMID: 32351394]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 919)
  AUTHORS   Gorlier,C., Sellam,J., Laurans,L., Simon,T., Giurgea,I.,
            Bastard,J.P., Fellahi,S., Deshayes,S., Grateau,G., Ait Oufella,H.
            and Georgin-Lavialle,S.
  TITLE     In familial Mediterranean fever, soluble TREM-1 plasma level is
            higher in case of amyloidosis
  JOURNAL   Innate Immun 25 (8), 487-490 (2019)
   PUBMED   31474164
REFERENCE   5  (bases 1 to 919)
  AUTHORS   Zhu,H., Li,W., Wang,Z., Chen,J., Ding,M. and Han,L.
  TITLE     TREM-1 deficiency attenuates the inflammatory responses in
            LPS-induced murine endometritis
  JOURNAL   Microb Biotechnol 12 (6), 1337-1345 (2019)
   PUBMED   31365951
REFERENCE   6  (bases 1 to 919)
  AUTHORS   Gibot,S., Massin,F., Marcou,M., Taylor,V., Stidwill,R., Wilson,P.,
            Singer,M. and Bellingan,G.
  TITLE     TREM-1 promotes survival during septic shock in mice
  JOURNAL   Eur J Immunol 37 (2), 456-466 (2007)
   PUBMED   17230441
REFERENCE   7  (bases 1 to 919)
  AUTHORS   Gibot,S., Alauzet,C., Massin,F., Sennoune,N., Faure,G.C.,
            Bene,M.C., Lozniewski,A., Bollaert,P.E. and Levy,B.
  TITLE     Modulation of the triggering receptor expressed on myeloid cells-1
            pathway during pneumonia in rats
  JOURNAL   J Infect Dis 194 (7), 975-983 (2006)
   PUBMED   16960786
REFERENCE   8  (bases 1 to 919)
  AUTHORS   Determann,R.M., Weisfelt,M., de Gans,J., van der Ende,A.,
            Schultz,M.J. and van de Beek,D.
  TITLE     Soluble triggering receptor expressed on myeloid cells 1: a
            biomarker for bacterial meningitis
  JOURNAL   Intensive Care Med 32 (8), 1243-1247 (2006)
   PUBMED   16786330
REFERENCE   9  (bases 1 to 919)
  AUTHORS   Knapp,S., Gibot,S., de Vos,A., Versteeg,H.H., Colonna,M. and van
            der Poll,T.
  TITLE     Cutting edge: expression patterns of surface and soluble triggering
            receptor expressed on myeloid cells-1 in human endotoxemia
  JOURNAL   J Immunol 173 (12), 7131-7134 (2004)
   PUBMED   15585833
REFERENCE   10 (bases 1 to 919)
  AUTHORS   Bouchon,A., Hernandez-Munain,C., Cella,M. and Colonna,M.
  TITLE     A DAP12-mediated pathway regulates expression of CC chemokine
            receptor 7 and maturation of human dendritic cells
  JOURNAL   J Exp Med 194 (8), 1111-1122 (2001)
   PUBMED   11602640
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473987.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001063859.1, XM_217336.4.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN16676784,
                              SAMN16676787 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..919
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q12"
     gene            1..919
                     /gene="Trem1"
                     /note="triggering receptor expressed on myeloid cells 1"
                     /db_xref="GeneID:301229"
                     /db_xref="RGD:1309467"
     exon            1..357
                     /gene="Trem1"
                     /inference="alignment:Splign:2.1.0"
     CDS             87..632
                     /gene="Trem1"
                     /codon_start=1
                     /product="triggering receptor expressed on myeloid cells
                     1"
                     /protein_id="NP_001100355.1"
                     /db_xref="GeneID:301229"
                     /db_xref="RGD:1309467"
                     /translation="MKYARSRKAWQRLSAGKEPLTLVVTERSSTTSSEVRVGKYTLKD
                     DPTEAMLFVQMTDLQVTDSGLYRCVIYHPPNDPVLLFHPVRLVVTKGSSGVSVPDIIP
                     TTKPTEVPVLITTKHSTPTRSLPKSTAVVSSPDPGVTINNGTDPTSVSTYNVVVPVVC
                     GLLIKTLIFFVLFVVTKRSFG"
     exon            358..529
                     /gene="Trem1"
                     /inference="alignment:Splign:2.1.0"
     exon            530..919
                     /gene="Trem1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aagtcaaagc tgccattgtc ccagaggaag aaaggtatga tctagttgag ggccagacct
       61 tgacagtgaa ctgtcccttc aacatcatga agtatgccag aagcaggaag gcttggcaga
      121 ggctatcagc tgggaaggaa cccttgaccc tggtggtcac agagaggtcc tctacaacat
      181 ccagtgaagt ccgtgtgggg aagtacaccc tgaaagatga ccctaccgag gccatgttat
      241 ttgttcaaat gactgacctt caagtgacag actctggatt atatcgttgt gtgatttacc
      301 atcctccgaa cgaccctgtt ctgctcttcc atcccgtccg cctggtggtg accaagggtt
      361 cttcaggtgt gtccgttcct gacatcattc ctaccacaaa gccgactgag gttcccgtcc
      421 tcattaccac aaaacactca actccaaccc gatccctacc caagtccact gctgttgttt
      481 cctctcctga tcctggagtc accatcaaca atgggacaga tcctacgagt gtctccacat
      541 acaatgttgt tgttcccgtg gtctgtgggc tcctcatcaa aactctgatc ttcttcgtct
      601 tattcgttgt cacaaagagg tcatttggat gacagatctt gaagctacac aatagtgacc
      661 ttcagccatg tctatctcac agaaggagct gacatggggg ggggtataga ggaactgtga
      721 cacgaattga gcctgtaatc ataggtgaca tctaaggctc aggatgtccc cacctggtcc
      781 tgcccaccct cctcatctca tccatcattt agggaacatg ttctgcaccc tcaggaaaga
      841 ggaaccaatt cctagaacac tctggtcttt cccccttaat aggtgggttt gtctgaaata
      901 aagacagagc aaagtactt
//
