LOCUS       NM_001109004            1930 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus TRAF-interacting protein (Traip), mRNA.
ACCESSION   NM_001109004 XM_001074679 XM_345981
VERSION     NM_001109004.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1930)
  AUTHORS   Feng W, Guo Y, Huang J, Deng Y, Zang J and Huen MS.
  TITLE     TRAIP regulates replication fork recovery and progression via PCNA
  JOURNAL   Cell Discov 2, 16016 (2016)
   PUBMED   27462463
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1930)
  AUTHORS   Zhang M, Wang L, Zhao X, Zhao K, Meng H, Zhao W and Gao C.
  TITLE     TRAF-interacting protein (TRIP) negatively regulates IFN-beta
            production and antiviral response by promoting proteasomal
            degradation of TANK-binding kinase 1
  JOURNAL   J Exp Med 209 (10), 1703-1711 (2012)
   PUBMED   22945920
REFERENCE   3  (bases 1 to 1930)
  AUTHORS   Zhou Q and Geahlen RL.
  TITLE     The protein-tyrosine kinase Syk interacts with TRAF-interacting
            protein TRIP in breast epithelial cells
  JOURNAL   Oncogene 28 (10), 1348-1356 (2009)
   PUBMED   19151749
REFERENCE   4  (bases 1 to 1930)
  AUTHORS   Besse A, Campos AD, Webster WK and Darnay BG.
  TITLE     TRAF-interacting protein (TRIP) is a RING-dependent ubiquitin
            ligase
  JOURNAL   Biochem Biophys Res Commun 359 (3), 660-664 (2007)
   PUBMED   17544371
REFERENCE   5  (bases 1 to 1930)
  AUTHORS   Lee SY, Lee SY and Choi Y.
  TITLE     TRAF-interacting protein (TRIP): a novel component of the tumor
            necrosis factor receptor (TNFR)- and CD30-TRAF signaling complexes
            that inhibits TRAF2-mediated NF-kappaB activation
  JOURNAL   J Exp Med 185 (7), 1275-1285 (1997)
   PUBMED   9104814
REFERENCE   6  (bases 1 to 1930)
  AUTHORS   Logue SF, Paylor R and Wehner JM.
  TITLE     Hippocampal lesions cause learning deficits in inbred mice in the
            Morris water maze and conditioned-fear task
  JOURNAL   Behav Neurosci 111 (1), 104-113 (1997)
   PUBMED   9109628
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC162006.1.
            
            On Apr 6, 2008 this sequence version replaced NM_001109004.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC162006.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1930
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..1930
                     /gene="Traip"
                     /note="TRAF-interacting protein"
                     /db_xref="GeneID:367167"
                     /db_xref="RGD:1309761"
     exon            1..179
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     CDS             82..1491
                     /gene="Traip"
                     /EC_number="2.3.2.27"
                     /codon_start=1
                     /product="E3 ubiquitin-protein ligase TRAIP"
                     /protein_id="NP_001102474.1"
                     /db_xref="GeneID:367167"
                     /db_xref="RGD:1309761"
                     /translation="MPIRALCTICSDFFDHSRDVAAIHCGHTFHLQCLIQWFETAPSR
                     TCPQCRIQVGKKTIINKLFFDLAQEEESVLDAEFLKNELDSIKAQLSQKDREKRDSQA
                     IIDTLRDTLEERNATVESLQNALNKAEMLCSTLKKQMKFLEQQRDETKHAQEEARQLK
                     SKMKTMEQIELLLQSQRSEVEEMIRDMGVGQSAVEQLAVYCISLKKEYENLKEARKAS
                     GELADRLRKDLASSRSKLKTVNTELDQAKLELRSAQKDLQSADKEITSLRKKLTILQG
                     TLSLPPVTSETVSRLVFESPAPVEMLKPRLHRPPFSDEIDLNATFDVNTPPAQTSSSQ
                     HCHPKKLCLERARSPMQDILKIPKVSKSESQLSLGGQRCVGEPDEELAGAFPLFIRNA
                     VRGQKQPNRTTAESRYSTDVVRIGFDGLGGRTKFIQPTDPTIIRPMPVKPKAKSKQKV
                     RIKTVNSASQPKLDTFLCQ"
     exon            180..237
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            238..321
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            322..361
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            362..489
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            490..584
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            585..698
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            699..786
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            787..876
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            877..965
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1121
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1167
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            1168..1317
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            1318..1368
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
     exon            1369..1905
                     /gene="Traip"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtgggaaccg cggccggttc ggccacccaa ctgtgtctgt tgctggctgc tggctctctg
       61 tgctgcttga gccgagccat catgcctatc cgcgcgctgt gcactatctg ctccgatttc
      121 ttcgatcact cccgtgacgt ggctgccatc cactgtggcc acacttttca tctgcaatgc
      181 ctaatccagt ggtttgagac agcaccaagt cggacctgcc cccagtgtag aatccaggtt
      241 ggcaaaaaga ctatcatcaa caagctcttt tttgaccttg cccaggaaga ggagagtgtc
      301 ttggatgcag aattcttaaa gaatgaactg gacagtatca aggcccagct ctcccaaaaa
      361 gacagggaga aacgggacag ccaggccatt atcgacactc tacgggacac attggaggaa
      421 cgcaatgcca ctgtggagtc cctgcagaac gccttaaaca aggcagagat gctgtgttcc
      481 accctgaaaa aacagatgaa attcctggag cagcagcggg atgagaccaa acacgctcag
      541 gaggaggccc gccaactcaa gagcaagatg aaaaccatgg agcaaattga gctcctactc
      601 cagagccagc ggtctgaggt agaggagatg atccgagaca tgggtgtggg acagtcagcg
      661 gtggagcagc tagctgtgta ctgcatatcc ctcaagaaag agtatgagaa tctgaaagaa
      721 gctcggaagg cctcagggga gctggctgac aggctgagga aagacttggc gtcttctagg
      781 agcaagctga agactgtcaa cactgagctg gatcaggcca agttagaact gaggtcagcc
      841 cagaaggact tacagagcgc tgacaaggag atcacgagcc taagaaagaa gctaacgatc
      901 ctgcagggga ccttgagcct gcctccagtg accagtgaga ctgtcagccg cctggttttt
      961 gagagcccag cccccgtgga aatgctgaag ccaaggcttc accgaccacc cttcagtgat
     1021 gagattgatc tcaacgctac ctttgatgta aatacccctc ctgcccagac ctccagctcc
     1081 cagcattgcc accccaagaa gctctgcctg gagagggcac gctctcccat gcaggacatc
     1141 ctcaagatac ccaaagtctc caagtcggag tcccagctct cactgggtgg ccagcgatgt
     1201 gtaggagagc cagatgagga gctggctggt gccttccctc tcttcatccg gaatgctgtc
     1261 cggggtcaga aacagcccaa caggaccaca gcagaatccc gttacagcac agatgtggta
     1321 agaataggct tcgatgggct tggaggacga acaaaattca tccaacctac agacccaacc
     1381 attatccgac caatgcctgt taaacccaag gccaagagta aacagaaagt gagaataaag
     1441 actgtgaatt ctgcctccca gcccaagctg gataccttct tatgtcagtg aagtgaccag
     1501 agtcatgtct tcaatcagta gaccaagacc tggccaaccg gaagtgtttt agaagatggc
     1561 tcctcttgga acagtctaag aaagaggccc agaaaacaca cttactgtgt tcactgcgcc
     1621 ctgtaccaca ctgggaagtg acgtgaccag tttacagttc tgatcagcag ggcctgcttc
     1681 tagttgcagg gttttgctta tagctacaac tgggagtggc tgggctcctt ctggttttat
     1741 agaacagggt cacattgact cttaagtgga cggaagtgct ggaggattcc taagcaggcc
     1801 accttgaact tctgcctgcc tccagtttta ttgcttgaaa tgggggtttt ggggggatga
     1861 tagggaaggt ttccgtgtaa aataaaaagg catcttttct tctagaaaaa aaaaaaaaaa
     1921 aaaaaaaaaa
//
