LOCUS       NM_053760               2466 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus TRAF type zinc finger domain containing 1
            (Trafd1), mRNA.
ACCESSION   NM_053760 XM_001076427 XM_341086
VERSION     NM_053760.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2466)
  AUTHORS   Sanada,T., Takaesu,G., Mashima,R., Yoshida,R., Kobayashi,T. and
            Yoshimura,A.
  TITLE     FLN29 deficiency reveals its negative regulatory role in the
            Toll-like receptor (TLR) and retinoic acid-inducible gene I
            (RIG-I)-like helicase signaling pathway
  JOURNAL   J Biol Chem 283 (49), 33858-33864 (2008)
   PUBMED   18849341
REFERENCE   2  (bases 1 to 2466)
  AUTHORS   Cattaruzza,M., Schafer,K. and Hecker,M.
  TITLE     Cytokine-induced down-regulation of zfm1/splicing factor-1 promotes
            smooth muscle cell proliferation
  JOURNAL   J Biol Chem 277 (8), 6582-6589 (2002)
   PUBMED   11748220
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000012.1.
            
            On or before Oct 23, 2008 this sequence version replaced
            XM_341086.2, XM_001076427.1, NM_053760.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360176.776944.1,
                                           SRR26360194.988585.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-81                JAXUCZ010000012.1  40826251-40826331
            82-146              JAXUCZ010000012.1  40827852-40827916
            147-282             JAXUCZ010000012.1  40832859-40832994
            283-336             JAXUCZ010000012.1  40833067-40833120
            337-742             JAXUCZ010000012.1  40833744-40834149
            743-949             JAXUCZ010000012.1  40834719-40834925
            950-1026            JAXUCZ010000012.1  40836408-40836484
            1027-1257           JAXUCZ010000012.1  40837041-40837271
            1258-1378           JAXUCZ010000012.1  40837853-40837973
            1379-1712           JAXUCZ010000012.1  40838439-40838772
            1713-1785           JAXUCZ010000012.1  40839213-40839285
            1786-2466           JAXUCZ010000012.1  40839489-40840169
FEATURES             Location/Qualifiers
     source          1..2466
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="12"
                     /map="12q16"
     gene            1..2466
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /note="TRAF type zinc finger domain containing 1"
                     /db_xref="GeneID:114635"
                     /db_xref="RGD:620171"
     exon            1..81
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            82..146
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     CDS             100..1845
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /note="FLN29 gene product"
                     /codon_start=1
                     /product="TRAF-type zinc finger domain-containing protein
                     1"
                     /protein_id="NP_446212.2"
                     /db_xref="GeneID:114635"
                     /db_xref="RGD:620171"
                     /translation="MAEFPDDQAARLCDNCKKEIPVFNFTIHEIHCQRNIGVCPVCKE
                     PFPKSDMDIHVATEHCQVTCKCNKKLEKRQLKQHVETECPLRLAVCQHCDLELSVVKL
                     KEHEDYCGARTELCGSCGRNVLVKELQTHPAVCGRVEEEKRSEAAVPPEAYDEPWSQD
                     RIWIASQLLRQIEALDPPMRLPGRPLRAFEADPFYSRTASQRGVTAHFPIQNNLFEEQ
                     ERQERNRSHQSPKDSAENSAHLDFMLALSLQNEGQASSMVEQGFWESVPEADPARAGP
                     TSLGDIKGAADETLLPCEFCEELYPEELLIDHQTSCNPSHALRSLNTGSSSIRGVEDP
                     GAIFQNFLQQATSNQLDTLMGLSSSAAVEDSIIIPCEFCGVQLEEEVLFHHQDQCDQR
                     PATANHRAMEGIPTQDSQPEDRSPELSRRRVKHQGDLSSGYMDDVKQESVKGSTYSLS
                     PNRTMNNVSTCNRLLNSSGPRSDCQRSPPGVLKLNNSGSQDIRGRIRGSQNGPIASAH
                     APVIHSIRNLYPENLAPSFPHGSPGRFGASGRSEGSRSSRVTPTAASYHSRAAKAKPP
                     KQQGAGDAEEEEEEE"
     exon            147..282
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            283..336
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            337..742
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            743..949
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1026
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            1027..1257
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            1258..1378
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            1379..1712
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            1713..1785
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
     exon            1786..2466
                     /gene="Trafd1"
                     /gene_synonym="Fln29"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaagcggctg ggcagcgagg ccgttgttgg ctcggggcgg ccgaggcgac tgtggcggtg
       61 gcgttcccgc tgggctctga gttttcagga agagccaaga tggccgagtt tccagatgac
      121 caggctgcta ggctgtgtga caactgcaaa aaggaaattc cggtatttaa ttttaccatc
      181 catgaaatcc actgtcaaag gaacattggt gtgtgccctg tctgcaagga accattcccg
      241 aagtccgaca tggacattca cgtggctaca gagcactgtc aggtgacctg caaatgcaac
      301 aagaagctgg agaagaggca gttaaagcag catgtggaga ctgagtgtcc tctgcgcctt
      361 gctgtctgcc agcactgtga tctggagctt tctgttgtca agttgaagga gcatgaggat
      421 tactgtggtg cccggacaga gctgtgtggc agctgtgggc gcaacgtgct tgtaaaggag
      481 ttgcagactc accctgctgt ttgtgggaga gtggaggagg agaagagaag cgaggccgct
      541 gtccctcctg aggcttacga cgagccttgg agtcaggata gaatctggat cgcatcccag
      601 cttctcagac agatcgaggc tctggaccca cccatgaggc tccctggaag gcccctgaga
      661 gcctttgagg cagacccttt ctacagtagg actgccagcc agaggggcgt gacagcccat
      721 tttcccattc aaaataatct ttttgaagag caagaaaggc aggaaaggaa cagaagccac
      781 cagtccccaa aagacagtgc tgagaatagc gcacacttgg acttcatgtt ggccctgagt
      841 ctgcagaatg agggacaggc ctccagcatg gtagagcagg gcttctggga gtctgtgccg
      901 gaggccgacc ccgctcgtgc tgggcccaca tctctaggtg acataaaggg tgctgctgac
      961 gagactctcc tgccctgtga gttctgtgag gagctgtacc cggaggaact gctcattgac
     1021 catcagacaa gctgcaaccc ttcacatgcc ttacgttcac tcaatactgg cagctcttcc
     1081 attagggggg tggaagatcc tggtgccatc ttccagaact ttctacaaca agcaacaagt
     1141 aaccagttag acactttaat gggcctgagc agttcagctg ctgtggaaga cagcattatc
     1201 atcccctgtg agttctgtgg ggtgcagctg gaagaggagg tgctgttcca ccatcaggat
     1261 caatgtgacc agcgcccagc cacagcaaac caccgagcaa tggagggcat ccctacacag
     1321 gattctcagc ctgaagaccg ttcaccagag ctgtccagga ggcgggtcaa acaccaggga
     1381 gacctgtcgt ctggctacat ggatgatgtc aagcaggaat cagtgaaagg ctccacctac
     1441 tcgctgtctc ccaacagaac catgaacaat gtgtctacct gtaaccgact gttgaactca
     1501 tcaggcccca ggtctgactg ccagcgtagc cctcctggtg tgctgaagct caacaactca
     1561 ggcagccagg acatccgtgg gcggattaga ggcagccaga atgggcccat agcatctgcg
     1621 catgctccag tgatccactc tattcgaaat ctctatccag aaaaccttgc gccctctttt
     1681 cctcatggct cccctgggag attcggagcc agtgggagga gtgaaggcag tcggagctct
     1741 cgggtcaccc ctacagccgc cagctaccac agcagagcag caaaggcaaa gcctccgaag
     1801 cagcagggag caggggatgc agaggaggag gaagaggagg agtaatggcg actgtggggg
     1861 gctcttgcag ccacccctat gcatagcagt acctgctggt gcagtgtcca actgcctcgc
     1921 aggctcattg ggcaggagag acaccagatt gtaatttttc ctatgttatg gccattttgt
     1981 gtctttgaga ttgtgcagtg ggtattgggg tttgagggag ggctagctgg gaggcccgag
     2041 ctgccactgt tgagcagcag tgaaatcagt gtctgtggcc ctcttggccc taagggctcc
     2101 atccttagag atgtcgtcag cactgcttct tggtgctttg tggtcctgct ggacagagag
     2161 gagggttctg ggaatctcag ataccagtga agcaattctc tccccctggg ggcctaagct
     2221 tgggtttgca gcatgttagg aacaagctga gcggcaggta tatggcagga ctagaggcca
     2281 ccttggtgct tgcgggtcac tcacccacct ctctgctcct ggtggggaat gtactgctct
     2341 gttcgtgctg ccctcaccag ggccacacct gccctcacag ggactgaagc tccagcccct
     2401 tcccttctta ttttactggt ttaattattt ccttgtaata gaaataaagt ttgtatttag
     2461 agctca
//
