LOCUS       NM_001398701            2239 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus TNF receptor-associated factor 5 (Traf5),
            transcript variant 1, mRNA.
ACCESSION   NM_001398701 XM_039091510
VERSION     NM_001398701.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2239)
  AUTHORS   Huan,W., Wu,X., Zhang,S., Zhao,Y., Xu,H., Wang,N., Li,H., Chen,H.,
            Wei,H. and Wang,Y.
  TITLE     Spatiotemporal patterns and essential role of TNF
            receptor-associated factor 5 expression after rat spinal cord
            Injury
  JOURNAL   J Mol Histol 43 (5), 527-533 (2012)
   PUBMED   22484641
  REMARK    GeneRIF: Our data suggested that TRAF5 might play important roles
            in CNS pathophysiology after spinal cord injury .
REFERENCE   2  (bases 1 to 2239)
  AUTHORS   Woodsmith,J., Jenn,R.C. and Sanderson,C.M.
  TITLE     Systematic analysis of dimeric E3-RING interactions reveals
            increased combinatorial complexity in human ubiquitination networks
  JOURNAL   Mol Cell Proteomics 11 (7), M111.016162 (2012)
   PUBMED   22493164
REFERENCE   3  (bases 1 to 2239)
  AUTHORS   Jakobsen,L., Vanselow,K., Skogs,M., Toyoda,Y., Lundberg,E.,
            Poser,I., Falkenby,L.G., Bennetzen,M., Westendorf,J., Nigg,E.A.,
            Uhlen,M., Hyman,A.A. and Andersen,J.S.
  TITLE     Novel asymmetrically localizing components of human centrosomes
            identified by complementary proteomics methods
  JOURNAL   EMBO J 30 (8), 1520-1535 (2011)
   PUBMED   21399614
REFERENCE   4  (bases 1 to 2239)
  AUTHORS   Hostager,B.S., Fox,D.K., Whitten,D., Wilkerson,C.G., Eipper,B.A.,
            Francone,V.P., Rothman,P.B. and Colgan,J.D.
  TITLE     HOIL-1L interacting protein (HOIP) as an NF-kappaB regulating
            component of the CD40 signaling complex
  JOURNAL   PLoS One 5 (6), e11380 (2010)
   PUBMED   20614026
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 2239)
  AUTHORS   Gil,J., Garcia,M.A., Gomez-Puertas,P., Guerra,S., Rullas,J.,
            Nakano,H., Alcami,J. and Esteban,M.
  TITLE     TRAF family proteins link PKR with NF-kappa B activation
  JOURNAL   Mol Cell Biol 24 (10), 4502-4512 (2004)
   PUBMED   15121867
REFERENCE   6  (bases 1 to 2239)
  AUTHORS   Matsuda,A., Suzuki,Y., Honda,G., Muramatsu,S., Matsuzaki,O.,
            Nagano,Y., Doi,T., Shimotohno,K., Harada,T., Nishida,E., Hayashi,H.
            and Sugano,S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
REFERENCE   7  (bases 1 to 2239)
  AUTHORS   Lee,S.W., Han,S.I., Kim,H.H. and Lee,Z.H.
  TITLE     TAK1-dependent activation of AP-1 and c-Jun N-terminal kinase by
            receptor activator of NF-kappaB
  JOURNAL   J Biochem Mol Biol 35 (4), 371-376 (2002)
   PUBMED   12296995
REFERENCE   8  (bases 1 to 2239)
  AUTHORS   Zapata,J.M., Pawlowski,K., Haas,E., Ware,C.F., Godzik,A. and
            Reed,J.C.
  TITLE     A diverse family of proteins containing tumor necrosis factor
            receptor-associated factor domains
  JOURNAL   J Biol Chem 276 (26), 24242-24252 (2001)
   PUBMED   11279055
REFERENCE   9  (bases 1 to 2239)
  AUTHORS   Nakano,H., Sakon,S., Koseki,H., Takemori,T., Tada,K., Matsumoto,M.,
            Munechika,E., Sakai,T., Shirasawa,T., Akiba,H., Kobata,T.,
            Santee,S.M., Ware,C.F., Rennert,P.D., Taniguchi,M., Yagita,H. and
            Okumura,K.
  TITLE     Targeted disruption of Traf5 gene causes defects in CD40- and
            CD27-mediated lymphocyte activation
  JOURNAL   Proc Natl Acad Sci U S A 96 (17), 9803-9808 (1999)
   PUBMED   10449775
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000013.1.
            
            On Dec 21, 2021 this sequence version replaced XM_039091510.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643297.42540.1,
                                           SRR26643295.47967.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-357               JAXUCZ010000013.1  106149351-106149707 c
            358-576             JAXUCZ010000013.1  106129164-106129382 c
            577-634             JAXUCZ010000013.1  106125361-106125418 c
            635-736             JAXUCZ010000013.1  106120941-106121042 c
            737-901             JAXUCZ010000013.1  106117146-106117310 c
            902-979             JAXUCZ010000013.1  106116035-106116112 c
            980-1054            JAXUCZ010000013.1  106115656-106115730 c
            1055-1147           JAXUCZ010000013.1  106113446-106113538 c
            1148-1288           JAXUCZ010000013.1  106108165-106108305 c
            1289-1457           JAXUCZ010000013.1  106105365-106105533 c
            1458-2239           JAXUCZ010000013.1  106103291-106104072 c
FEATURES             Location/Qualifiers
     source          1..2239
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="13"
                     /map="13q27"
     gene            1..2239
                     /gene="Traf5"
                     /note="TNF receptor-associated factor 5"
                     /db_xref="GeneID:684173"
                     /db_xref="RGD:1593883"
     exon            1..357
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            358..576
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     CDS             359..2035
                     /gene="Traf5"
                     /codon_start=1
                     /product="TNF receptor-associated factor 5"
                     /protein_id="NP_001385630.1"
                     /db_xref="GeneID:684173"
                     /db_xref="RGD:1593883"
                     /translation="MAHSEEQAVVPCAFIRQNSGNSISLDFEPDTEYQFVEQLEERYK
                     CAFCHSVLHNPHQTGCGHRFCQHCILSLRELNSVPICPVDKEVIKPQEVFKDNCCKRE
                     VLNLHVYCKNAPGCNARIILGRFQDHLQHCSFQAVPCPNQSCREAMLRKDVKEHLSAY
                     CRFREEKCLYCKRDIVVTNLQDHEENSCPAYPVSCPNKCVQTIPRAGVKEHLTVCPEA
                     EQDCPFKHYGCTVKGKRGNLQEHERAALQDHMLLVLEKNFQLEQQISDLYQSLEQKES
                     KIQQLAGTVKKFEKELKQFTQMFGRNGSFLSNVQALTSHTDKSAWLEAQVRQLLQIVN
                     QQQSRLDLRSLVDAVDSVKQRITQLEASDQRLVVLEGETNKHDAHINIHKAQLNKNEE
                     RFKLLEGACYSGKLIWKVTDYKAKKREAMEGHTVSVFSQPFYTSRCGYRLCARAYLNG
                     DGSGKGTHLSLYFVVMRGEFDSLLQWPFRQRVTLMLLDQSGKKNHIVETFKADPNSSS
                     FRRPDGEMNIASGCPRFVSHSTLESSRNTYIKDDTLFLKVAVDLTDLEDL"
     exon            577..634
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            635..736
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            737..901
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            902..979
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            980..1054
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1055..1147
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1148..1288
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1457
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
     exon            1458..2239
                     /gene="Traf5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agccggctgc ggaggcgaag cagccttgcc ctcgccgccg tagggcgccc gcggaactcc
       61 gcgagccccg caagtgggaa aggccgggtg agctcaccat cccggctcct cagaaaccga
      121 aagcggctca gggaggtggg ttggaggcgt gtgtgttagc gggtggactg aggcgacccg
      181 ggacatccgc gcccggcccg gggcactttt gcaagacttg tgaacacagc ccattaacgt
      241 gagcttaatg ccagggactc gaacctgcac cggtgctata gcgcgtgctc atttggagat
      301 agcacccgac tctgcagaag ctgagttcca gatttcggca gacccaggcg cctagagaat
      361 ggctcattca gaggagcaag cggttgtgcc ctgtgccttc atccgccaga actctggcaa
      421 ctccatttcc ttggactttg agcccgacac agagtaccaa tttgtggagc agctggaaga
      481 acgctacaaa tgtgccttct gccactcggt gcttcacaac ccccaccaga cgggctgtgg
      541 gcaccgcttc tgccagcact gcatcctgtc tctgagagaa ttgaactcgg tgccgatctg
      601 ccccgtagac aaggaggtga tcaagcctca ggaggtgttt aaagacaact gctgcaaaag
      661 agaagttctc aacttacacg tctactgcaa aaacgcacct ggatgcaatg ccaggattat
      721 tctgggacgg ttccaggacc accttcagca ctgctccttc caagctgtgc cctgccccaa
      781 ccagagctgc cgggaagcca tgctccggaa agatgtgaaa gagcatctga gtgcctactg
      841 ccggttccga gaggagaagt gcctttactg caagagggac atagtggtga ctaacctgca
      901 ggatcatgag gaaaactcgt gtcctgcata tccagtgtct tgtcccaaca agtgtgtgca
      961 gactattccg agagctgggg tgaaggaaca cctcactgtg tgccctgagg ctgagcaaga
     1021 ctgtcccttt aagcactatg gctgcacggt caagggcaag cgtgggaact tgcaggagca
     1081 cgagcgggca gccctgcagg accacatgct tctggtttta gagaagaact tccaactaga
     1141 acagcagatc tctgacttat atcagagtct cgagcagaaa gaaagcaaga tccagcagct
     1201 tgcaggaact gtgaagaagt tcgagaaaga gcttaagcag ttcacacaga tgttcggcag
     1261 aaatggaagt ttcctctcaa atgtccaggc tctcaccagt cacacggaca agtcggcttg
     1321 gctggaagcg caggtgcggc agctgctaca aatagttaac cagcagcaaa gccggcttga
     1381 tctgaggtct ttggtggatg ctgtggacag tgtgaaacag aggatcaccc agctggaggc
     1441 cagtgaccag agattagttg ttttagaggg ggagaccaat aagcacgacg cacacattaa
     1501 tatccacaaa gcacagctga ataagaacga agaacggttt aagctgctgg agggcgcctg
     1561 ctacagtggc aagctcattt ggaaggtgac agattacaag gcgaagaaga gggaggctat
     1621 ggaggggcac acagtgtccg tcttcagcca gcctttctat accagccgct gtggctaccg
     1681 gctctgtgcc agagcgtacc tgaacgggga tgggtcgggg aagggaacgc acctgtcttt
     1741 gtactttgtg gtgatgcggg gtgagttcga ctcactatta cagtggccat tcaggcagag
     1801 ggtgacacta atgcttttgg atcagagtgg caagaagaac cacattgtgg agaccttcaa
     1861 agctgacccc aatagcagca gcttcagaag accggacggg gagatgaaca ttgcctctgg
     1921 ctgtccccgc tttgtttctc attctactct ggagagttcc aggaacacct acattaaaga
     1981 cgacacccta ttcttgaaag tggccgtgga tttaactgac ttggaggatc tgtaaatgtt
     2041 aactgatagc tccacacagg agccgatgtg actgtccttt aagccatgcc ctttgggcgg
     2101 agcatgcttt tgttcttatc ttcctgcctt taatgtccga tgtgacacct tggatccttc
     2161 cccggttcga aacgtcagac tcttagctgt tatttatatt tttatatctt ctgagaaatt
     2221 ataataattt gtcaatagg
//
