LOCUS       NM_001044248            2088 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus Traf3 interacting protein 2 (Traf3ip2), mRNA.
ACCESSION   NM_001044248 XM_001061443 XM_342152
VERSION     NM_001044248.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2088)
  AUTHORS   Ryzhakov G, Blazek K, Lai CC and Udalova IA.
  TITLE     IL-17 receptor adaptor protein Act1/CIKS plays an evolutionarily
            conserved role in antiviral signaling
  JOURNAL   J Immunol 189 (10), 4852-4858 (2012)
   PUBMED   23066157
REFERENCE   2  (bases 1 to 2088)
  AUTHORS   Ho AW, Shen F, Conti HR, Patel N, Childs EE, Peterson AC,
            Hernandez-Santos N, Kolls JK, Kane LP, Ouyang W and Gaffen SL.
  TITLE     IL-17RC is required for immune signaling via an extended SEF/IL-17R
            signaling domain in the cytoplasmic tail
  JOURNAL   J Immunol 185 (2), 1063-1070 (2010)
   PUBMED   20554964
REFERENCE   3  (bases 1 to 2088)
  AUTHORS   Qian Y, Qin J, Cui G, Naramura M, Snow EC, Ware CF, Fairchild RL,
            Omori SA, Rickert RC, Scott M, Kotzin BL and Li X.
  TITLE     Act1, a negative regulator in CD40- and BAFF-mediated B cell
            survival
  JOURNAL   Immunity 21 (4), 575-587 (2004)
   PUBMED   15485634
REFERENCE   4  (bases 1 to 2088)
  AUTHORS   Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y,
            Doi T, Shimotohno K, Harada T, Nishida E, Hayashi H and Sugano S.
  TITLE     Large-scale identification and characterization of human genes that
            activate NF-kappaB and MAPK signaling pathways
  JOURNAL   Oncogene 22 (21), 3307-3318 (2003)
   PUBMED   12761501
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC100099.1.
            
            On or before Aug 24, 2006 this sequence version replaced
            XM_342152.3, XM_001061443.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100099.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760386, SAMEA5760400
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2088
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="20"
                     /map="20q12"
     gene            1..2088
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /note="Traf3 interacting protein 2"
                     /db_xref="GeneID:361857"
                     /db_xref="RGD:1593240"
     exon            1..95
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
     exon            96..914
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
     CDS             104..1780
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /EC_number="2.3.2.27"
                     /note="adapter protein CIKS"
                     /codon_start=1
                     /product="E3 ubiquitin ligase TRAF3IP2"
                     /protein_id="NP_001037713.1"
                     /db_xref="GeneID:361857"
                     /db_xref="RGD:1593240"
                     /translation="MNRSIPVEVDESEPFPSQLLNPIPESSPEEELEPPAPNTRNTAP
                     SSLSVLQRPPLKLANHQPVSQQVTCLRAKVLEESEASFLRRHPDLGKDVSSCSSEASE
                     PGSELGALSLEHRFTHMEKRDRWLGPQLSAASPDTGHDSDKSDPSLPMALADSSSSDQ
                     EMRPRPGSRPRPWPRHHRNRAAPDVPTIDTGYDSQPQDVLGIRQLEKPLPLTSSCYLQ
                     DLPGPLRSKEFPQFELQRYPANAPMLPLDPSPQVPWSYQYCRPGGPYHHQAPYGHGYP
                     PAAAYQQVIQPALPEQALLGARVRGLHPMQKVVLNDSSPQDQEERPAQRDFSFSRLPR
                     DRLCRPPSNGAGAPEESLDRPAELRPHGPQALSPAAVPRPPSNPLARGTLKTSNLPEE
                     LRKVFITYSMDTAMEVVKCVNFLLVNGFQTAIDIFEDRIRGIDIIKWMERYLRDKTVM
                     IIVAISPKYKQDVEGTGSQLDEDEHGLHTKYIHRMMQIEFINQGSMNFRFIPVLFPNA
                     KKEHVPTWLQNTHVYSWPKNKKNILLRLLREEEYVAPPRGPLPTLQVVPL"
     exon            915..1104
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1283
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
     exon            1284..1372
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
     exon            1373..1441
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
     exon            1442..1558
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
     exon            1559..1633
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
     exon            1634..2055
                     /gene="Traf3ip2"
                     /gene_synonym="RGD1304768"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagagggcg agggaggtct gagcggcccg aggtggatcc cggagagcag agcccgcgac
       61 caccccctgg gcccgtctgt cggtggcgat cttagaaact agaatgaatc gaagcattcc
      121 cgtggaggtt gacgaatcgg agcccttccc gagtcagttg ctgaatccga tcccagaatc
      181 ttctccagaa gaggaattgg aaccacctgc cccaaataca aggaacacgg cacccagcag
      241 cttgtctgta ctccaacgcc ctcccctgaa acttgcaaat caccagcctg tgtcgcaaca
      301 ggtcacctgc ttgcgagcta aagtcctgga ggagagtgaa gccagtttcc ttagaaggca
      361 ccctgatctc ggcaaagatg tttcctcctg ctcctctgaa gccagtgagc ctgggtctga
      421 gcttggagcc ctctctctag agcatcgctt tacacatatg gaaaaacgcg atagatggct
      481 gggacctcag ctttcagcag cttctcccga cactggccat gactcagaca aatcagaccc
      541 aagtttgcct atggctttgg cagactcctc cagtagtgac caagagatga ggcccaggcc
      601 cgggtcccgg ccccggccct ggccccggca ccacaggaac agggcagccc cagatgtgcc
      661 cacgatagac actgggtatg attcccagcc ccaagatgtc ctgggcatca ggcagctgga
      721 aaagcccttg cccctcacct cctcatgtta cctgcaggac ctccctgggc ctctcaggtc
      781 caaggaattt ccccagtttg aactccagag gtatccggcg aatgcgccga tgctgcctct
      841 cgatccttcc ccacaggttc catggagtta tcagtactgt cgtcccggag ggccctatca
      901 ccaccaggcg ccatatggtc atggctaccc tccagcagca gcctaccagc aagtcatcca
      961 gcctgctctg cctgagcagg cccttctcgg ggcaagggtg agaggcctgc accctatgca
     1021 gaaggtcgtc ctgaatgact ccagccccca ggaccaagaa gagaggcctg cacagcgaga
     1081 cttctctttc tcaaggctcc caagggaccg gctctgccgc ccaccatcta atggagctgg
     1141 agctcccgag gagtccttgg accgtcctgc agagctgaga ccacatggtc cccaggctct
     1201 gtccccagct gccgtgccta gaccccctag caacccctta gcccgaggaa ctctgaaaac
     1261 cagcaatttg ccagaggaat tacggaaggt ctttatcact tattctatgg acacagccat
     1321 ggaggtggtg aagtgtgtga acttcctgct ggtgaatggc ttccaaaccg ccattgacat
     1381 atttgaggac agaatccggg gtattgatat cattaaatgg atggagcgct accttcgaga
     1441 taagacagtg atgataatcg tagcaatcag ccccaaatac aaacaggatg tggaaggcac
     1501 tgggtcgcag ctggacgagg atgagcatgg cttacatact aagtacattc atcggatgat
     1561 gcagatcgag tttataaatc agggaagcat gaatttcagg ttcatccctg tgctcttccc
     1621 aaatgccaag aaggagcatg tgccgacctg gctgcagaac actcacgtgt acagctggcc
     1681 caagaataag aaaaacatcc ttctgcggct gctccgagag gaggagtacg tagctcctcc
     1741 ccgaggccct ctgcccaccc ttcaggtggt acctttgtga tgccagcctg ttctcacagc
     1801 attcgtccag ccaagctggt tggtggcact caggcctgga acacctgttc tacagagttc
     1861 ccggcctcct gagtctgagg tgtcctcgcc cggcctccag tgcttctggg agtggatgtt
     1921 gcaggtgatg gctgcccgga cctatggcca caaaaactct catcacttca gctactctta
     1981 tgagttggcc ggatgctttg tgtccttaga ccagtctgaa tcgtgctcaa ttaataaagt
     2041 gattattctt tgtaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaa
//
