LOCUS       NM_001126296            1857 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus transformer 2 alpha (Tra2a), mRNA.
ACCESSION   NM_001126296 XM_575468 XR_007448
VERSION     NM_001126296.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1857)
  AUTHORS   Baltz,A.G., Munschauer,M., Schwanhausser,B., Vasile,A.,
            Murakawa,Y., Schueler,M., Youngs,N., Penfold-Brown,D., Drew,K.,
            Milek,M., Wyler,E., Bonneau,R., Selbach,M., Dieterich,C. and
            Landthaler,M.
  TITLE     The mRNA-bound proteome and its global occupancy profile on
            protein-coding transcripts
  JOURNAL   Mol Cell 46 (5), 674-690 (2012)
   PUBMED   22681889
REFERENCE   2  (bases 1 to 1857)
  AUTHORS   Castello,A., Fischer,B., Eichelbaum,K., Horos,R., Beckmann,B.M.,
            Strein,C., Davey,N.E., Humphreys,D.T., Preiss,T., Steinmetz,L.M.,
            Krijgsveld,J. and Hentze,M.W.
  TITLE     Insights into RNA biology from an atlas of mammalian mRNA-binding
            proteins
  JOURNAL   Cell 149 (6), 1393-1406 (2012)
   PUBMED   22658674
REFERENCE   3  (bases 1 to 1857)
  AUTHORS   Grellscheid,S., Dalgliesh,C., Storbeck,M., Best,A., Liu,Y.,
            Jakubik,M., Mende,Y., Ehrmann,I., Curk,T., Rossbach,K.,
            Bourgeois,C.F., Stevenin,J., Grellscheid,D., Jackson,M.S., Wirth,B.
            and Elliott,D.J.
  TITLE     Identification of evolutionarily conserved exons as regulated
            targets for the splicing activator tra2beta in development
  JOURNAL   PLoS Genet 7 (12), e1002390 (2011)
   PUBMED   22194695
REFERENCE   4  (bases 1 to 1857)
  AUTHORS   Park,E., Han,J., Son,G.H., Lee,M.S., Chung,S., Park,S.H., Park,K.,
            Lee,K.H., Choi,S., Seong,J.Y. and Kim,K.
  TITLE     Cooperative actions of Tra2alpha with 9G8 and SRp30c in the RNA
            splicing of the gonadotropin-releasing hormone gene transcript
  JOURNAL   J Biol Chem 281 (1), 401-409 (2006)
   PUBMED   16249178
REFERENCE   5  (bases 1 to 1857)
  AUTHORS   Lieberman,A.P., Friedlich,D.L., Harmison,G., Howell,B.W.,
            Jordan,C.L., Breedlove,S.M. and Fischbeck,K.H.
  TITLE     Androgens regulate the mammalian homologues of invertebrate sex
            determination genes tra-2 and fox-1
  JOURNAL   Biochem Biophys Res Commun 282 (2), 499-506 (2001)
   PUBMED   11401487
REFERENCE   6  (bases 1 to 1857)
  AUTHORS   Tacke,R., Tohyama,M., Ogawa,S. and Manley,J.L.
  TITLE     Human Tra2 proteins are sequence-specific activators of pre-mRNA
            splicing
  JOURNAL   Cell 93 (1), 139-148 (1998)
   PUBMED   9546399
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC161978.1 and JAXUCZ010000004.1.
            
            On Mar 28, 2013 this sequence version replaced NM_001126296.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC161978.1, SRR26643429.16324.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760389,
                                           SAMEA5760393 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1812              BC161978.1         1-1812
            1813-1857           JAXUCZ010000004.1  79551699-79551743   c
FEATURES             Location/Qualifiers
     source          1..1857
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q24"
     gene            1..1857
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /note="transformer 2 alpha"
                     /db_xref="GeneID:500116"
                     /db_xref="RGD:1562563"
     exon            1..200
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..1013
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /note="transformer 2 alpha homolog"
                     /codon_start=1
                     /product="transformer-2 protein homolog alpha"
                     /protein_id="NP_001119768.2"
                     /db_xref="GeneID:500116"
                     /db_xref="RGD:1562563"
                     /translation="MSDVEENNFEGRESRSQSKSPTGTPARVKSESRSGSRSPSRVSK
                     HSESHSRSRSKSRSRSRRHSHRRYTRSRSHSHRRRSRSRSYTPEYRRRRSRSHSPMSN
                     RRRHTGSRANPDPNTCLGVFGLSLYTTERDLREVFSRYGPLSGVNVVYDQRTGRSRGF
                     AFVYFERIDDSKEAMERANGMELDGRRIRVDYSITKRAHTPTPGIYMGRPTHSGGGGG
                     GGGGGGGGGGGGGRRRDSYYDRGYDRGYDRYEDYDYRYRRRSPSPYYSRYRSRSRSRS
                     YSPRRY"
     exon            201..334
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /inference="alignment:Splign:2.1.0"
     exon            335..494
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /inference="alignment:Splign:2.1.0"
     exon            495..683
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /inference="alignment:Splign:2.1.0"
     exon            684..799
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /inference="alignment:Splign:2.1.0"
     exon            800..934
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /inference="alignment:Splign:2.1.0"
     exon            935..1002
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1857
                     /gene="Tra2a"
                     /gene_synonym="RGD1562563"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ccggcgccat tttgcccgag cgtgcgagct agtgggagtg gaacgcaccg gccgttgtag
       61 ccgtcgcctt cttcctcccc acagtcaaac agcgcggtga ctaggccgtc ggccctcgag
      121 ccgagacata tctcttgttt agtgctcggg agcgcctggc caacatgagt gatgtagagg
      181 agaacaactt cgagggcaga gagtctcgct ctcagtcaaa atctccaacg ggaactcctg
      241 ctcgtgtaaa atcagagagc aggtcaggat ctcgtagtcc atcaagggtt tccaaacatt
      301 ctgaatccca ttctcgatca agatcaaaat ccaggtcgag gtcacggagg cattctcata
      361 gacgctacac gcgatccagg tcacactctc acagaagacg gtcgcgaagt aggtcctata
      421 caccagagta caggcggagg aggagccgga gccactcccc catgtcaaac cgcagaaggc
      481 acactggcag cagggcaaac ccagatccta acacttgcct gggagtattt ggcctcagtc
      541 tgtatacaac agagagagat cttcgtgaag ttttttctcg atatggacct ctgagtggtg
      601 ttaatgtggt ttatgatcag cgaactggga ggtcacgcgg gtttgctttt gtgtattttg
      661 agaggataga tgactctaag gaggctatgg aaagagcaaa tgggatggag ctggatggta
      721 gaagaattcg tgtggattat tctatcacca agagagcaca cacacctaca ccaggcattt
      781 acatgggcag accaactcac agtggtggtg gaggtggcgg aggaggaggt ggtggcggcg
      841 gtggtggtgg aggtggtaga cggcgagatt cttactacga tagaggatat gatcgaggct
      901 atgacagata tgaagattat gattaccggt acagaagaag gtcgccttct ccttactaca
      961 gtcgctacag gtcacgatca agatcccgtt cctatagccc aagacgctat tgataccgga
     1021 gcgattgtgc cccaggactt tgcttcctct ttttggtttt tggatttcca agcttccaat
     1081 gtttcctttt aaaaacaaaa aacaaaaaaa cctggtttat ttaacctctg tgtggccagt
     1141 tgtgttgctg ttcttcaccc tttgttaaac tcttaaaggt gtaattgtct tttcagtagt
     1201 tgaacatctc gagtaaagga gcaccatgct gtgctttgtg gttcttcttt gccttacaga
     1261 ggattaactt cttacgatga ggaaagaaac catcttttga aagctttttc tgatggacat
     1321 tgtagtagac attagaaatc tgtggtatga caaactgctt tttaatcttc tttggcagaa
     1381 gacaacactt tggataggtc agtcctgtca ggcttgtctg gagtggcatg gagcagttga
     1441 atagttgagt gtagaaagtt tgaagctcta ggagaaaata tgggacattt cttttgaaga
     1501 atataacttt gaacgtaaaa attaagtcac cttttagaaa ttaaaagctt gtaattccta
     1561 taagacatgt tgtatttgaa tttacatgtt aaaccttatt ataaacttaa agtgtgattt
     1621 ttatgttaag tttacggaaa ctttattccc ttaatcactg aaggacaacc tttatttatt
     1681 acctagaaca attgtataac ttgctgttag aaattttggt attgggacat tggttacatg
     1741 ggttattgta taggatccta aataatacat gtggggaaga gtaatttcaa ataaaagtta
     1801 atttgaaaat gggattgtct ctttgataac agtggaaaat acatatttta tatacaa
//
