LOCUS       XM_039105059            2953 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus TPX2, microtubule nucleation factor
            (Tpx2), transcript variant X2, mRNA.
ACCESSION   XM_039105059
VERSION     XM_039105059.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051338.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039105059.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2953
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..2953
                     /gene="Tpx2"
                     /note="TPX2, microtubule nucleation factor; Derived by
                     automated computational analysis using gene prediction
                     method: Gnomon. Supporting evidence includes similarity
                     to: 1 mRNA, 5 ESTs, 7 Proteins, and 100% coverage of the
                     annotated genomic feature by RNAseq alignments, including
                     127 samples with support for all annotated introns"
                     /db_xref="GeneID:311546"
                     /db_xref="RGD:1311894"
     CDS             394..2628
                     /gene="Tpx2"
                     /codon_start=1
                     /product="targeting protein for Xklp2 isoform X1"
                     /protein_id="XP_038960987.1"
                     /db_xref="GeneID:311546"
                     /db_xref="RGD:1311894"
                     /translation="MAQVPTAYSFDAPTDFINFSSLDAEEDTENIDSWFDEKANLENK
                     FLRQSGIGEPFQGKTSLRKAKLQQGCVTPLKAVDNTYYKETEKENLQKQSIPSNDCPS
                     LNAKRAVTGTTPIQPQRRSVRLSAQKDLEQKEKNHVASVEMKAKRCTAPTTDYPPNKK
                     MKVSHKKKPEEEEEGSAPATSRKDETLERAKGKHTVPAVPPAREKTVKSTEEQELEKS
                     LRMQQEVVEMRKKNEEFKKLALAGPGQPVKKSTSQVTKTVDFHFLTDERIKQHPKSQE
                     EYKEVNFMSELRKHSSTPARGTRGCTIIKPFNLSKGKKRTFDEAASTYVPIAQQVEAF
                     HKRTPNRYHLRNKKDESLLPSKPVNKIVRDPQTPILQTKYRARAVTCKSAAEKEAEEL
                     EKLQQYKFKARELDPRIFESGPILPKRPPVKPPTQPVGFDLEIEKRIHERESKKKPED
                     EQFEFHSRPCPTKILEDVVGVPEKKVIPATVPKSPVFALKNRIRVPVKEDEEEEKPVV
                     IKAQPVPHYGVPYKPPIPETRNVEVCPFSFDTRDKERQLQKEKKIKEMQKGEVPKFKA
                     LPVPHFDTINLPEKKVKNATQAEPFSLETDKRGAYKAEIWKHQLEEEQKQQKEAACFK
                     ARPNTVIFQEPFVPKKEKKSAAENPSGSLVQEPFQLATEKRAKERQELEKKMAEMEAW
                     KLQQLAEVRQQEEEQQKEELARLRKELVHKANPIRKYSAVEVKSSELPLTVPVSPKFS
                     TRFQ"
ORIGIN      
        1 aagcagcggt gcgccgggag ccattcctca gttttctgag agggtggagg agtccgcggg
       61 gcgggccatg ccagcctaga cagcgcgcgg gcttcggacg ccggggtcgg gacttgggag
      121 tgaagtctca gattcggctt cagtattcct gggaaccccg gagcagaggt tgctccaggc
      181 tgtcagctac tagacggtaa cggctgttgg tgttcttcat gagaagtgtc tgccggactg
      241 taatacttca agagacttga gagcgagatt gtgactttga ggtgaggttg taagaagtgg
      301 acttgagaga caaatttact atagatcaga ggacgatcta ttgagtggag tattagaatc
      361 ctggaaaaag tgtgttctgc actaggtggg gcaatggccc aagtcccaac agcttactcg
      421 tttgatgccc ccaccgactt tatcaacttt tcatctttgg atgctgaaga ggacactgaa
      481 aatatagact catggtttga tgagaaggcc aacttggaga acaagtttct tcggcagagt
      541 ggaataggag aaccttttca ggggaagacg tccttgagaa aagccaaact tcaacaaggc
      601 tgtgtcacac cattgaaggc agttgataac acttactaca aagagacaga aaaggaaaat
      661 cttcagaagc aatctatccc atcaaatgat tgtccttccc tgaatgctaa gagagctgtg
      721 acaggaacta ctcccatcca gcctcagaga agatctgtta gactctctgc tcagaaggat
      781 ttggagcaga aagagaaaaa ccatgttgcc tctgttgaaa tgaaagccaa gagatgcact
      841 gctcccacga ctgattatcc ccccaacaag aaaatgaaag tgtctcataa aaagaaaccg
      901 gaggaagaag aggagggcag tgctccagct acttcaagaa aggatgaaac tctggagagg
      961 gccaagggca aacacactgt gcctgctgtg ccgcctgcca gggagaagac tgtaaagagt
     1021 actgaagagc aggagttaga gaagagtctg agaatgcagc aggaagtggt agagatgcgg
     1081 aagaagaatg aagagtttaa gaagctggct cttgcagggc cagggcaacc tgtgaagaaa
     1141 tccaccagcc aggttaccaa gacagttgac tttcacttcc tcacagatga gagaatcaaa
     1201 caacatccca agagccagga ggagtataag gaagtgaact tcatgtccga acttcgaaag
     1261 cattcttcca ctcctgcccg agggaccaga ggatgtacca tcattaagcc tttcaatctg
     1321 tccaaaggaa agaaaagaac atttgacgaa gcagcgtcta catatgtgcc cattgcacag
     1381 caggttgaag ccttccacaa acgaacccct aatcgatacc atctgaggaa caagaaggac
     1441 gagagcttgt taccctccaa acctgtgaac aagattgtac gagaccccca gacccctata
     1501 ctgcagacca aataccgtgc aagggctgtg acctgcaaaa gtgcggcaga gaaggaggcc
     1561 gaggaacttg agaaactgca acaatacaaa ttcaaagcac gggaacttga tcccagaatt
     1621 tttgaaagtg gccccatctt gcccaagaga ccacctgtta agcctcctac ccagcctgtt
     1681 ggttttgatt tggaaattga gaaacgaatt catgagcgag agtcaaagaa aaaacccgaa
     1741 gatgaacaat ttgaatttca ttccagacct tgccctacta agatcttgga agatgttgtg
     1801 ggtgttcctg aaaagaaggt tattccagcc actgtcccta agtcaccagt ttttgcactg
     1861 aagaacagga tccgagtgcc tgtcaaagaa gatgaggaag aggagaaacc agtagtgata
     1921 aaagctcaac ctgtgccaca ttatggggtg ccttataaac cccccatccc agagacaaga
     1981 aatgtggagg tgtgcccgtt ctcctttgat acccgggaca aagaacgcca gttgcagaag
     2041 gagaaaaaaa taaaagaaat gcagaaagga gaggtgccca agttcaaggc acttcctgtg
     2101 ccccattttg acaccattaa cctgccagag aaaaaggtaa agaatgcgac tcaagccgag
     2161 cctttctcct tggagacaga caagagaggt gcctacaagg ccgagatatg gaagcaccag
     2221 ctggaagaag agcagaagca gcagaaggaa gcagcttgct tcaaggctcg tccaaacact
     2281 gtcatcttcc aagagccctt tgttcccaag aaagagaaaa aatcagctgc tgagaaccct
     2341 tctggttctc tagttcagga accttttcag ctggccaccg agaagagagc caaagagcgg
     2401 caggagctgg agaagaaaat ggctgagatg gaggcctgga aactgcagca gttggcagaa
     2461 gtcaggcagc aggaagagga gcagcagaag gaggagctgg ccaggctccg gaaggaactg
     2521 gtgcacaagg caaatccaat ccgaaagtac tcagcagtgg aggtgaaatc cagtgagctg
     2581 cctctgaccg tgccggtgtc tcctaagttc tccactcggt tccagtagaa gccgccgcat
     2641 gtacaccaca ggcacagaga acacgttttc agactcacct acgtgtgtgg aaacatacct
     2701 gagaactgtg gaggccaggt tttgaagatc gagttacatg gagactttga agctaatgag
     2761 acagcactca tttagactca tcagacttcc tgtagttatt tcctgcagac attagctggc
     2821 cctttcctgt tggtcataac tctggccagg acttcaacta ttcattttgg catagtctac
     2881 ttttcaccta atctccccct tctccccctt tatatatgta ttttaagcat aaaataaagg
     2941 cagtcaagtc cta
//
