LOCUS       NM_001419185            2811 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus transmembrane phosphoinositide 3-phosphatase and
            tensin homolog 2 (Tpte2), transcript variant 2, mRNA.
ACCESSION   NM_001419185 XM_039094732
VERSION     NM_001419185.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2811)
  AUTHORS   Walker,S.M., Downes,C.P. and Leslie,N.R.
  TITLE     TPIP: a novel phosphoinositide 3-phosphatase
  JOURNAL   Biochem J 360 (Pt 2), 277-283 (2001)
   PUBMED   11716755
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Mar 29, 2023 this sequence version replaced XM_039094732.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643293.75754.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760389 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-577               JAXUCZ010000016.1  76455070-76455646   c
            578-673             JAXUCZ010000016.1  76454000-76454095   c
            674-724             JAXUCZ010000016.1  76446036-76446086   c
            725-781             JAXUCZ010000016.1  76441144-76441200   c
            782-835             JAXUCZ010000016.1  76439980-76440033   c
            836-892             JAXUCZ010000016.1  76438290-76438346   c
            893-946             JAXUCZ010000016.1  76436608-76436661   c
            947-994             JAXUCZ010000016.1  76431172-76431219   c
            995-1045            JAXUCZ010000016.1  76428144-76428194   c
            1046-1099           JAXUCZ010000016.1  76426388-76426441   c
            1100-1153           JAXUCZ010000016.1  76423948-76424001   c
            1154-1219           JAXUCZ010000016.1  76421876-76421941   c
            1220-1270           JAXUCZ010000016.1  76417103-76417153   c
            1271-1432           JAXUCZ010000016.1  76415170-76415331   c
            1433-1552           JAXUCZ010000016.1  76413066-76413185   c
            1553-1652           JAXUCZ010000016.1  76410913-76411012   c
            1653-1716           JAXUCZ010000016.1  76410734-76410797   c
            1717-1781           JAXUCZ010000016.1  76409246-76409310   c
            1782-1842           JAXUCZ010000016.1  76400189-76400249   c
            1843-1924           JAXUCZ010000016.1  76399341-76399422   c
            1925-2013           JAXUCZ010000016.1  76399133-76399221   c
            2014-2075           JAXUCZ010000016.1  76391298-76391359   c
            2076-2156           JAXUCZ010000016.1  76389173-76389253   c
            2157-2262           JAXUCZ010000016.1  76384322-76384427   c
            2263-2354           JAXUCZ010000016.1  76381084-76381175   c
            2355-2447           JAXUCZ010000016.1  76375532-76375624   c
            2448-2518           JAXUCZ010000016.1  76362951-76363021   c
            2519-2811           JAXUCZ010000016.1  76361333-76361625   c
FEATURES             Location/Qualifiers
     source          1..2811
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16q12.5"
     gene            1..2811
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /note="transmembrane phosphoinositide 3-phosphatase and
                     tensin homolog 2"
                     /db_xref="GeneID:364629"
                     /db_xref="RGD:1305825"
     exon            1..577
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            578..673
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     CDS             615..2639
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /EC_number="3.1.3.48"
                     /note="transmembrane phosphatase with tensin homology"
                     /codon_start=1
                     /product="phosphatidylinositol-3,4,5-trisphosphate
                     3-phosphatase TPTE2"
                     /protein_id="NP_001406114.1"
                     /db_xref="GeneID:364629"
                     /db_xref="RGD:1305825"
                     /translation="MQGVKKSHLYLWMEHYGYDGPASSRVYSQLSRRRRNANKKVLSS
                     TSKSTKLNGSIGYDGNEETTTFTNGSSIDSMSYQDDMKSSNCMDPTSEKRYGNDSSLY
                     TIDGTLNNGTTLYEMNSLSELSKEVYLNDSALLRGKEAASELSQVSSTMKTQSSVSTS
                     ILSTSDLISEEIQEEQINKCKLNQISKLYDEDEHVDIRESYWSTVKKFVHFLVSSVAF
                     RIFGILLIFLDVFLVAIDLHATEKNIYIPLEYRAISLAIALFFLVDVLLRVYVEGRQR
                     YFSDVLNTLDAVVIGVTVLVAVIYTLYDKQFLRNIPRLAVLLRPLRLLILVRILQLAH
                     QKRQLEKLTRQLVSGNKRRYKKDGFDLDLTYVTERIIAMSFPSSGRESFYRNPIKEVV
                     RFLDTKHPNHYQVYNLCSERSYDPKRFHYRVRRIMIDDHNVPTLEEMLLFSKEVNDWM
                     AQDPENVVAIHCKGGKGRTGTMVCACLIASEIVLNAKASLYFFGERRTDKSNSSKFQG
                     VETPSQNRYVKYFEKLKTSYQLTLPPKKVLVIKRFTVYSIHGVGKGNGSDLEIQIMMW
                     QETIFSCFNSKNCMIFHDVETDKVIINVFNCPALYDDVKVKFLCPNLPKYYDDCPFFF
                     WFHTSFIRNNRLYLPRSELDNTHKQKTWKIYGPKFAVEVYFEEISSTVMY"
     exon            674..724
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            725..781
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            782..835
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            836..892
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            893..946
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            947..994
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            995..1045
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1099
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1100..1153
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1154..1219
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1220..1270
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1432
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1433..1552
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1553..1652
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1653..1716
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1717..1781
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1782..1842
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1843..1924
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            1925..2013
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            2014..2075
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            2076..2156
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            2157..2262
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            2263..2354
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            2355..2447
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            2448..2518
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
     exon            2519..2811
                     /gene="Tpte2"
                     /gene_synonym="Tpte"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gataaagacc ttggggtgag ggtctgagca aggattttcc attccacttg ctggatccgt
       61 gttatctcat tctcactagg agaattttaa aagtgaacgt tttaggggaa gttctgttgg
      121 gcgaggctgg ggagcaaaga gggtttcctg ggggttgtta gggatacttg aacaggaagg
      181 tttgccttgc gctcatctgg ggagaacaca gatatgcctc ttgcttctcg gaggaacacc
      241 cagagcctcc accctggaca cgggaacttt tagactggca gatgtggtac tacccttgtt
      301 tctggccatg aattgactga tttcgttgat ttgggaggaa attaatatga aaagagaatg
      361 gagaaaaaga aaagctgtta ttctgaaggg cagcgggaga gaagactggt ggcaggaact
      421 ggagtgaact cagctcccgc ttcagtcaag aggtagctaa gccgtaagac actaactagg
      481 ccctgtgggt tcctctgccc agccctgctg cagggtctca ctgcagcagt cactcattct
      541 gagccccagc agcgcagaga aaaagcagtg ccttcagatt aattgtaaat tgagtttaat
      601 cacaaggcaa taccatgcag ggagtcaaaa agagccattt gtatctctgg atggagcact
      661 acggatacga tgggcctgca agttccaggg tgtattctca gctctccaga agaagacgca
      721 atgcaaacaa aaaggtgtta tcgagcacgt cgaagtccac taaactaaac ggcagcattg
      781 gctatgacgg aaatgaagag acaaccacgt tcactaacgg aagtagcatt gacagtatgt
      841 cgtatcaaga tgacatgaaa tcgtcaaatt gcatggaccc caccagtgaa aaaagatatg
      901 gaaatgattc gtcattatac accattgacg gaactttgaa caacggcaca accctgtatg
      961 aaatgaattc cttgagtgaa ttatcgaaag aagtatacct gaacgattct gctttgctac
     1021 gtggtaaaga agctgccagc gaacttagcc aagtctcaag tacaatgaaa acacaatcat
     1081 ctgtgtcgac cagcattctc agcacatctg atttaatatc agaagaaatc caggaagagc
     1141 aaatcaacaa atgcaagtta aaccagatct ccaagctgta cgacgaggac gagcatgttg
     1201 acatccgaga gtcatactgg agcacagtta agaaatttgt gcatttcctt gtgtcctcag
     1261 ttgccttcag aatatttgga atactcctga tctttctgga tgtatttctt gtggctatcg
     1321 atctacatgc cactgaaaag aatatttata ttcctttgga atatcgggcc atttctttag
     1381 ctattgcttt atttttcctt gtggatgttc ttctccgagt gtatgtagaa gggagacagc
     1441 gttatttctc tgacgtgctg aacaccctag atgctgttgt catcggcgtg actgtgctcg
     1501 tggctgtcat ttatacactt tatgacaaac agtttctcag aaatattcca agactggcag
     1561 tcttacttcg gcctctgcga ctgctcatcc tggtaagaat tttgcagctg gcccatcaga
     1621 agcgacaact ggaaaagctg actcggcagc tggtttcggg taacaagcga cgctacaaga
     1681 aggatggctt cgacctggac ctcacttacg tcactgagcg cattattgcc atgtcatttc
     1741 catcatctgg aagggagtcc ttctatagaa atccaattaa ggaagttgtc aggttcctcg
     1801 acaccaagca tccaaaccac tatcaagtct acaatctatg cagtgagaga tcttatgacc
     1861 ctaagcgctt ccactacagg gtccgcagaa tcatgattga tgatcataac gtacctaccc
     1921 tcgaggaaat gttgttgttc tccaaggaag taaatgattg gatggcccaa gatcctgaaa
     1981 atgttgtagc aattcactgt aagggaggaa aagggagaac tggaaccatg gtgtgtgcct
     2041 gcctcattgc cagtgaaata gtcctaaacg caaaggcaag tctgtacttt tttggagagc
     2101 gacggacaga taaaagtaac agctctaagt ttcaaggagt agagacccct tctcagaata
     2161 gatatgttaa atattttgaa aaactgaaaa ctagctacca attgactctt cctccaaaaa
     2221 aagtacttgt gataaaaaga ttcactgttt actccattca tggtgttgga aaaggcaatg
     2281 gaagtgatct agaaatacaa ataatgatgt ggcaggagac gattttttcc tgttttaatt
     2341 ccaaaaattg tatgatattt catgatgttg aaacagacaa agtaataatt aatgtgttca
     2401 actgtccggc tctatatgat gatgtaaaag tgaaatttct ctgtccgaat cttcctaaat
     2461 actatgatga ctgccccttt ttcttttggt ttcatacatc ttttattcga aataacaggc
     2521 tttatctacc aagaagcgaa ttggataata cccataaaca aaaaacatgg aaaatttatg
     2581 gtccaaagtt tgcagtcgag gtgtattttg aggagataag ctccacggtt atgtactagc
     2641 tgttgaataa gtgccgctcc ccttcttgga tagaattatg ttccagatcc gtgctacata
     2701 gtcatgtctt ctaacctatg tttttgatgg tatgtccgta ttttatatat atgtgagtgt
     2761 atatgcatgt acatatgttt ctgggaaata tattaaatgt atacaggaaa a
//
