LOCUS       NM_001110318            1839 bp    mRNA    linear   ROD 06-JUN-2024
DEFINITION  Rattus norvegicus tumor protein p63 regulated 1-like (Tprg1l),
            transcript variant 1, mRNA.
ACCESSION   NM_001110318 XR_009131
VERSION     NM_001110318.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1839)
  AUTHORS   Korber,C., Horstmann,H., Venkataramani,V., Herrmannsdorfer,F.,
            Kremer,T., Kaiser,M., Schwenger,D.B., Ahmed,S., Dean,C.,
            Dresbach,T. and Kuner,T.
  TITLE     Modulation of Presynaptic Release Probability by the
            Vertebrate-Specific Protein Mover
  JOURNAL   Neuron 87 (3), 521-533 (2015)
   PUBMED   26212709
  REMARK    GeneRIF: Mover expression in certain subsets of synapses negatively
            regulates synaptic release probability in the calyx of Held.
REFERENCE   2  (bases 1 to 1839)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 1839)
  AUTHORS   Kremer,T., Kempf,C., Wittenmayer,N., Nawrotzki,R., Kuner,T.,
            Kirsch,J. and Dresbach,T.
  TITLE     Mover is a novel vertebrate-specific presynaptic protein with
            differential distribution at subsets of CNS synapses
  JOURNAL   FEBS Lett 581 (24), 4727-4733 (2007)
   PUBMED   17869247
  REMARK    GeneRIF: mover may act in concert with generally expressed
            scaffolding proteins in distinct sets of presynaptic terminals
REFERENCE   4  (bases 1 to 1839)
  AUTHORS   Suzuki,H., Fukunishi,Y., Kagawa,I., Saito,R., Oda,H., Endo,T.,
            Kondo,S., Bono,H., Okazaki,Y. and Hayashizaki,Y.
  TITLE     Protein-protein interaction panel using mouse full-length cDNAs
  JOURNAL   Genome Res 11 (10), 1758-1765 (2001)
   PUBMED   11591653
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            EU220430.1 and BC160865.1.
            
            On Aug 31, 2012 this sequence version replaced NM_001110318.1.
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: EU220430.1, EX491715.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5756307, SAMEA5760383
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: lack of evidence for use of
                                                upstream AUG
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1816              EU220430.1         1-1816
            1817-1839           BC160865.1         1666-1688
FEATURES             Location/Qualifiers
     source          1..1839
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1839
                     /gene="Tprg1l"
                     /gene_synonym="mover"
                     /note="tumor protein p63 regulated 1-like"
                     /db_xref="GeneID:687090"
                     /db_xref="RGD:1590079"
     exon            1..443
                     /gene="Tprg1l"
                     /gene_synonym="mover"
                     /inference="alignment:Splign:2.1.0"
     CDS             169..969
                     /gene="Tprg1l"
                     /gene_synonym="mover"
                     /note="isoform 1 is encoded by transcript variant 1;
                     mossy-fiber terminal-associated vertebrate-specific
                     presynaptic protein; tumor protein p63-regulated gene
                     1-like protein"
                     /codon_start=1
                     /product="tumor protein p63-regulated gene 1-like protein
                     isoform 1"
                     /protein_id="NP_001103788.1"
                     /db_xref="GeneID:687090"
                     /db_xref="RGD:1590079"
                     /translation="MLQLRDTVDSAGTSPTAVLAAGEDAGAGRQGAGTPLRQTLWPLN
                     VHDPTRRARVKEYFVFRPGTIEQAVEEIRAVVRPVEDGEIQGVWLLTEVDHWNNEKER
                     LVLVTDQSLLICKYDFISLQCQQVVRVALSAVDTISCGEFQFPPKSLNKREGFGVRIQ
                     WDKQSRPSFINRWNPWSTNMPYATFIEHPMAGMDEKTASLCHLESFKALLIQAVKKAQ
                     KESPLPGQANNVLVLDRPLLIETYVGLMSFINNEAKLGYSMTRGKIGF"
     exon            444..620
                     /gene="Tprg1l"
                     /gene_synonym="mover"
                     /inference="alignment:Splign:2.1.0"
     exon            621..774
                     /gene="Tprg1l"
                     /gene_synonym="mover"
                     /inference="alignment:Splign:2.1.0"
     exon            775..1817
                     /gene="Tprg1l"
                     /gene_synonym="mover"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1806..1811
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Tprg1l"
                     /gene_synonym="mover"
     polyA_site      1817
                     /gene="Tprg1l"
                     /gene_synonym="mover"
ORIGIN      
        1 atgacttggc gaaaagccaa tcgtgagacg cagccgacgg agctggaggc gtgtccagaa
       61 ggcgggactt atgcagcgca gccaaccaca aggcggacga gggagggcgg ggcgcggctg
      121 ctgacggctg ggcggcggcc gtcggtggag ccggccggtg gcggcgtgat gctacagctg
      181 cgggacacag tggactcggc aggcacgagc cccacggcgg tgctggcggc cggcgaggat
      241 gcgggcgccg gacggcaggg ggcgggcacg ccgctgcgcc agactctgtg gccgctgaac
      301 gtccacgacc caacacgccg cgcccgcgtc aaggagtact tcgtgttccg acccggcact
      361 atcgagcagg cggtggagga gatccgcgcc gtggtacggc ccgtggagga cggcgagatc
      421 cagggggtgt ggctgctgac cgaggtggac cactggaaca acgagaagga gcggctggtg
      481 ctggtcaccg accagtcttt gctcatctgc aaatatgact tcatcagcct tcagtgtcag
      541 caggtggtca gggtggcgct cagtgcagta gacaccatct cctgtggaga attccagttt
      601 cctccaaagt cgctcaacaa gcgagaaggc tttggcgttc gcattcagtg ggacaagcag
      661 agccgccctt ctttcatcaa cagatggaac ccctggtcta caaacatgcc ctatgccacc
      721 ttcatagaac acccaatggc tggcatggat gagaagacag cgtctctgtg ccatttggaa
      781 agcttcaagg ctctcctaat ccaagctgtc aagaaagccc agaaggaaag cccactgcca
      841 gggcaggcga acaacgtgct ggtgctggac cgccctctcc tcatcgagac ctacgtgggg
      901 ctgatgtcct tcattaacaa tgaagccaag ctgggctact ccatgaccag gggcaagata
      961 ggcttctaga cagctgtgcc ccaggaaacc aaggtggtgg ggactccgtg tgccacctgt
     1021 cgacacctac cgtggctgga ggaacaaggg cattgtcctg ttatgtgtcc agttagaata
     1081 gtcaagtgga ccgtgtatat ttagttggat attggacacc ttggcaacac gatctcagcc
     1141 aggcagactc ggctgccccc ataccactgt gttccttctg taacaccatg cgctccctcc
     1201 tccagcatgc caagcacggt gtacccaccc acttgtgcag tgttgactgt tgaatacagc
     1261 agagtgcagg gagcggcttc cgcacatgca cacattaact ctccccgcca agtgctctat
     1321 tttaaaattc agtccccccc tttttttaaa tgctaactat aataacagcc agcagacagg
     1381 tcactaagaa agacagtctg cctggccagc tcctagtgaa tatgcctttc tgtgaatgtt
     1441 tgacttagga tctcacttta taaattaatg caggttgtgg taagtagccc cttccgcgag
     1501 tcttggtggt gggtctacat catcccgtct ctgtttaaaa gggactgatg agctgggttt
     1561 ccaagtgcat gcttagagca gcgagcgccc gggagcctcg ctgagcacca ctgagctttg
     1621 gcgcgcagcc acatgcagct tgccactgta gctctggcct tgcaaataca ctgtagatgt
     1681 cactttatac ctctagcttt aagttaaccg gcatggatgt gagcagaatg tcatggcctg
     1741 ttcaagagga aaggtgacct cagatgcacc tgtcttcagc ctgtgctttt gttctagtaa
     1801 agacaattaa aaccaaaaaa aaaaaaaaaa aaaaaaaaa
//
