LOCUS       XM_006244852            4696 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus tripeptidyl peptidase 2 (Tpp2),
            transcript variant X1, mRNA.
ACCESSION   XM_006244852
VERSION     XM_006244852.4
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051344.1) annotated using gene prediction method: Gnomon,
            supported by mRNA and EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_006244852.5.
            
            On Jan 21, 2021 this sequence version replaced XM_006244852.3.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4696
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..4696
                     /gene="Tpp2"
                     /gene_synonym="TPP-2"
                     /note="tripeptidyl peptidase 2; Derived by automated
                     computational analysis using gene prediction method:
                     Gnomon. Supporting evidence includes similarity to: 1
                     mRNA, 46 ESTs, 2 long SRA reads, 3 Proteins, and 100%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 173 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:81815"
                     /db_xref="RGD:621584"
     CDS             107..3895
                     /gene="Tpp2"
                     /gene_synonym="TPP-2"
                     /codon_start=1
                     /product="tripeptidyl-peptidase 2 isoform X1"
                     /protein_id="XP_006244914.2"
                     /db_xref="GeneID:81815"
                     /db_xref="RGD:621584"
                     /translation="MATAATEEPFPFHGLLPKKETGASSFLCRYPEYDGRGVLIAVLD
                     TGVDPGAPGMQVTTDGKPKIIDIIDTTGSGDVNTATEVEPKDGEITGLSGRVLKIPAN
                     WTNPSGKYHIGIKNGYDFYPKALKERIQKERKEKIWDPIHRVALAEACRKQEEFDIAN
                     NGSSQANKLIKEELQSQVELLNSFEKKYSDPGPVYDCLVWHDGETWRACVDSNENGDL
                     GKSTVLRNYKEAQEYGSFGTAEMLNYSVNIYDDGNLLSIVTSGGAHGTHVASIAAGHF
                     PEEPERNGVAPGAQILSIKIGDTRLSTMETGTGLIRAMIEVINHKCDLVNYSYGEATH
                     WPNSGRICEVINEAVWKHNTIYVSSAGNNGPCLSTVGCPGGTTSSVIGVGAYVSPDMM
                     VAEYSLREKLPANQYTWSSRGPSADGALGVSISAPGGAIASVPNWTLRGTQLMNGTSM
                     SSPNACGGIALVLSGLKANNVDYTVHSVRRALENTAIKADNIEVFAQGHGIIQVDKAY
                     DYLIQNTSFANRLGFTVTVGNNRGIYLRDPVQVAAPSDHGVGIEPVFPENTENSEKIS
                     FQLHLALTSNSSWVQCPSHLELMNQCRHINIRVDPRGLREGLHYTEVCGYDIASPNAG
                     PLFRVPITAVIAAKVNESSHYDLAFTDVHFKPGQIRRHFVEVPEGATWAEVTVCSCSS
                     EVSAKFVLHAVQLVKQRAYRSHEFYKFCSLPEKGTLIEAFPVLGGKAIEFCIARWWAS
                     LSDVNIDYTISFHGIVCTAPQLNIHASEGINRFDVQSSLKYEDLAPCITLKSWVQTLR
                     PVNAKTRPLGSRDVLPNNRQLYEMVLTYSFHQPKSGEVTPSCPLLCELLYESEFDSQL
                     WIIFDQNKRQMGSGDAYPHQYSLKLEKGDYTIRLQIRHEQISDLDRLKDLPFIVSHRL
                     SNTLSLDIHENHSLALLGKKKSSSLTLPPKYNQPFFVTSLPDDKIPKGAGPGCYLAGS
                     LTLSKTELGKKAGQSAAKRQGKFKKDVIPVHYYLIPPPTKTKNGSKDKEKDSEKEKDL
                     KEEFTEALRDLKIQWMTKLDSTDIYNELKETYPAYLPLYVARLHQLDAEKERMKRLNE
                     IVDAANAVISHIDQTALAVYIAMKTDPRPDAATIKNDMDKQKSTLVDALCRKGCALAD
                     HLLHAQPHDGAAAGDAEAKEEEGESTLESLSETYWETTKWTDLFDTKVLTFAYKHALV
                     NKMYGRGLKFATKLVEEKPTKENWKNCIQLMKLLGWTHCASFTENWLPIMYPPDYCVF
                     "
ORIGIN      
        1 gccccttccc ctcttccgtc ccgcggtcgc cgggtgtcct cgcgcccctc gtccgcgcgc
       61 tgcctggcag tttacctctt ccacgtccgt cctccagctt gcgtccatgg ccaccgctgc
      121 gaccgaggag cctttccctt tccatggtct tctaccaaag aaagagactg gggcctcctc
      181 cttcctgtgc cgctacccgg agtatgacgg acgcggggtg ctcatcgccg tcctggacac
      241 aggggttgat cccggggccc cgggcatgca ggtcacgact gatgggaaac caaaaatcat
      301 tgatatcatt gatacaacag gaagtggtga tgtgaatact gctacagaag tagaaccaaa
      361 agatggcgaa atcactggtc tttctggaag agtgcttaag attcctgcaa actggacaaa
      421 tccttcagga aaatatcata ttggcattaa aaatggttat gacttctatc caaaggctct
      481 caaggaaagg atacagaaag aacggaagga aaaaatctgg gatccaattc acagagttgc
      541 gcttgcagaa gcttgtagaa aacaagaaga atttgatatt gccaataatg gctcttccca
      601 agccaataaa ctaatcaagg aagagttgca gagtcaagtg gaattactta attcttttga
      661 gaaaaagtat agtgatccag gccctgtgta tgactgcttg gtgtggcatg atggtgagac
      721 ctggagagcc tgtgttgatt cgaatgaaaa tggggacttg ggtaaatcta ctgtattgag
      781 aaactacaaa gaggctcaag aatatggttc ttttggcaca gctgagatgc tgaattactc
      841 tgttaatatt tatgatgatg gaaacctgct ctccattgtg accagtggag gagctcatgg
      901 aacccatgta gcgagtatag ctgctgggca ttttccagaa gagcctgaac ggaatggagt
      961 tgctcctggt gctcaaattc tatccattaa gattggtgat acaaggctaa gcaccatgga
     1021 aacaggcaca ggcctcatca gagctatgat agaagttata aatcataagt gtgatcttgt
     1081 caactacagt tatggagaag caactcattg gccaaattct gggagaattt gtgaagtaat
     1141 taatgaagca gtatggaaac ataatacaat ttatgtttca agtgctggaa ataatggtcc
     1201 atgcctttct acagtgggtt gtccaggagg aactacttcc agcgtgatag gtgttggagc
     1261 ttatgtttct cctgatatga tggttgcaga gtattcactg agagagaaac tacctgcaaa
     1321 tcaatataca tggtcttcta gaggcccaag tgctgatggg gcccttggtg tgagcatcag
     1381 tgcaccagga ggtgctattg cttctgtgcc taactggaca ttgaggggga ctcagctaat
     1441 gaatgggaca tcaatgtctt cccccaatgc ctgtggtggc attgccctgg tactttcagg
     1501 actgaaagca aataatgttg actatactgt tcactcagtc agaagagctc tagaaaacac
     1561 tgcaataaaa gctgacaata tagaagtatt tgcccaagga catggaatta ttcaggttga
     1621 caaagcttat gactacctca ttcagaatac atcatttgct aacagattag gttttacagt
     1681 tacagttgga aataaccgtg gcatctacct ccgagatcct gttcaggtgg ctgctccttc
     1741 agatcatggt gttggcattg agcctgtatt tccagagaac acagaaaact ctgaaaaaat
     1801 atccttccag cttcatttag ctttaacttc aaattcatct tgggttcaat gtcccagcca
     1861 tttggaactc atgaatcaat gtcggcacat aaacatacgt gtggacccca ggggcttaag
     1921 agaagggtta cattatacag aggtatgtgg gtatgatata gcatccccca atgcaggtcc
     1981 tttattcaga gttccaatca ctgcagttat agcagcaaaa gtaaatgaat catcacatta
     2041 tgatctagcc tttacagatg tacattttaa acctggtcag attcgaagac attttgttga
     2101 ggttcctgag ggggcaactt gggctgaagt taccgtgtgt tcgtgttctt ctgaggtatc
     2161 agcaaaattt gttcttcatg cagtacagct tgtgaagcag agagcatatc gaagtcatga
     2221 attttataag ttttgttccc ttccagaaaa aggaacactc attgaagcct ttcctgttct
     2281 gggtgggaaa gcaattgaat tttgtattgc tcgttggtgg gcaagtctca gtgatgtcaa
     2341 tattgattat accatatcat tccatggcat agtgtgtact gcaccacagt taaacattca
     2401 tgcatctgaa ggaatcaatc gttttgatgt ccagtcctct ttaaaatatg aagatctggc
     2461 tccttgcata actttgaaga gctgggtgca aacactacgc ccagtaaatg caaaaaccag
     2521 acctttagga tcaagagatg ttttgccaaa taatcgccag ctttatgaga tggtcctgac
     2581 atacagcttt catcagccca agagcggaga agtaacacct agttgtccac tcctttgtga
     2641 attattatat gagtcagaat ttgacagtca gttgtggatt atttttgacc agaacaaaag
     2701 acagatgggc tcaggcgatg cctatccaca tcagtattct ttgaaattgg agaaaggaga
     2761 ttatacgatt cgattacaga ttcgtcatga gcaaatcagt gatttggatc gtctcaaaga
     2821 tcttccgttt attgtttcgc ataggttgtc taataccttg agcttagata ttcatgaaaa
     2881 tcatagcctt gcacttctag gaaagaagaa atcaagcagt ttgacattac cacccaaata
     2941 taatcagcca ttctttgtta cttccttacc tgatgataaa atacctaagg gggcaggacc
     3001 cggatgctac cttgcaggct ccttgacatt gtcaaagact gagcttggaa agaaagctgg
     3061 gcagtctgca gcaaaacgac aaggaaaatt taaaaaggat gtgatccctg ttcattacta
     3121 tctaatacct ccaccaacaa agactaagaa tggcagcaaa gataaagaaa aggattcaga
     3181 aaaagagaaa gatttgaaag aagagtttac tgaagcttta cgagatctta aaattcagtg
     3241 gatgaccaag ctggattcta ctgacattta caatgaattg aaagaaacat atcctgctta
     3301 ccttcctttg tatgttgcac gtcttcatca attagatgct gaaaaggagc ggatgaaaag
     3361 acttaatgaa attgttgatg ctgccaatgc tgttatttct cacatcgatc agaccgctct
     3421 cgctgtttac attgccatga agactgaccc caggcctgat gcagctacta taaaaaatga
     3481 tatggacaag cagaaatcta ccctggtaga tgccctctgc aggaaaggat gtgctctggc
     3541 agaccacctt cttcatgcac agccccacga tggggcagca gctggagatg cagaagcaaa
     3601 agaagaggaa ggagaaagta ccttggaatc tctatcagaa acctattggg aaactacaaa
     3661 gtggacagat ctttttgaca ctaaggtttt gacatttgca tacaagcatg cattagtaaa
     3721 taagatgtac gggagaggcc ttaagtttgc aaccaaactc gtagaagaaa aaccaacaaa
     3781 agaaaactgg aaaaattgta ttcaactaat gaaattactc ggatggaccc attgtgcgtc
     3841 ttttactgaa aactggctcc ccatcatgta tcctcctgat tattgtgtat tctaaaatgg
     3901 gaaccaaaac gttaaatttc gaaacagaaa attttatagt gaacaaatat atgaacaaat
     3961 gtgtggcatt tctagtctaa ctaatgcatg tcttcatcca ctatcgaata ctgatcatta
     4021 aaactctatg tatttatcag agaactcaat ggtgtgtggc ttcatacatg taatgtagac
     4081 agacctctga catcatgctg ctttcctgct gcctcccaca cttggctagg gagggcagag
     4141 cctgcctgcc agccccaacc tgggtgggat gcagctgctc actgcaggag aggttttcat
     4201 ctcttaattt ttaactgtaa aacgtcatcc agtttttatt ttataaatca aaaaggttaa
     4261 aacatgctaa atttttccaa ttatatagag gccttaaaaa tgctacattg ggtgtagcta
     4321 aattatttat ttgactaaaa attacgagaa cataatttcc agacttctaa aaataaattc
     4381 aattaatggg tatggtgggg aggtataaat acatggcaac tgggaaaaga aacgtgttaa
     4441 tgtaatcttc actccggagt cacaacaagc aagttgtttt tacagcatcc tcaagtacac
     4501 agcatcagaa taagttaaaa tttcatgtgt tggtgccagg cagttgaatc tatctggttt
     4561 tgtaaagata tacacagtat gtttataaca ttgaaatcat gtaaaataca tgaataaatg
     4621 tgcaaaacaa caggcacagc acaccatatg cactctgata cctgtttttt ataaataaaa
     4681 gtaaatattg aagcta
//
