LOCUS       NM_001376913            5971 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus testis and ovary specific TOPAZ 1 (Topaz1), mRNA.
ACCESSION   NM_001376913 XM_238565
VERSION     NM_001376913.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 5971)
  AUTHORS   Luangpraseuth-Prosper,A., Lesueur,E., Jouneau,L., Pailhoux,E.,
            Cotinot,C. and Mandon-Pepin,B.
  TITLE     TOPAZ1, a germ cell specific factor, is essential for male meiotic
            progression
  JOURNAL   Dev Biol 406 (2), 158-171 (2015)
   PUBMED   26358182
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 27, 2019 this sequence version replaced XM_238565.9.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643287.21670.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1169              JAXUCZ010000008.1  131235714-131236882
            1170-3597           JAXUCZ010000008.1  131237612-131240039
            3598-3662           JAXUCZ010000008.1  131246459-131246523
            3663-3787           JAXUCZ010000008.1  131247656-131247780
            3788-3852           JAXUCZ010000008.1  131253770-131253834
            3853-3986           JAXUCZ010000008.1  131258523-131258656
            3987-4072           JAXUCZ010000008.1  131262088-131262173
            4073-4198           JAXUCZ010000008.1  131262811-131262936
            4199-4262           JAXUCZ010000008.1  131263608-131263671
            4263-4414           JAXUCZ010000008.1  131268256-131268407
            4415-4507           JAXUCZ010000008.1  131268584-131268676
            4508-4623           JAXUCZ010000008.1  131272639-131272754
            4624-4690           JAXUCZ010000008.1  131276983-131277049
            4691-4865           JAXUCZ010000008.1  131278104-131278278
            4866-4966           JAXUCZ010000008.1  131279098-131279198
            4967-5132           JAXUCZ010000008.1  131283606-131283771
            5133-5297           JAXUCZ010000008.1  131284398-131284562
            5298-5501           JAXUCZ010000008.1  131285981-131286184
            5502-5685           JAXUCZ010000008.1  131287702-131287885
            5686-5971           JAXUCZ010000008.1  131290057-131290342
FEATURES             Location/Qualifiers
     source          1..5971
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q32"
     gene            1..5971
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /note="testis and ovary specific TOPAZ 1"
                     /db_xref="GeneID:301075"
                     /db_xref="RGD:1563398"
     exon            1..1169
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     CDS             953..5905
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /note="testis- and ovary-specific PAZ domain-containing
                     protein 1; testis and ovary specific PAZ domain containing
                     1"
                     /codon_start=1
                     /product="protein TOPAZ1"
                     /protein_id="NP_001363842.1"
                     /db_xref="GeneID:301075"
                     /db_xref="RGD:1563398"
                     /translation="MRPPTTPPVPTTAPGRQGATGGLRKRGLRLTPEPGEGGGCSLEA
                     RGREEESRQKRRMVAQASGREETEGDKLAKENGKVTEAPSDEPQPGTDLVRKTSITNS
                     ESLQTVECSEFQSMAFLQSLAKEELVEGIKRRIQIKKCKSSENPPLKITKNEATQNIM
                     VESQDELFKNTPKYSCNSLSPGVEKNCSFESHDFSFLHSEGCNNKNGFEDEPHGVCLH
                     AEENSLKSKKENLRNLAEKDDTKTTKFLKTEKNVIASKLLLEESHLYQNKNNGLTSCL
                     QSEKNKYSVEENNTGRKHRKKMKLSEKEEKGIDLTLSNVCNNSELVLQEHQIGMEGKE
                     TETLEHKKSFLKALRKMNHNTLPPVDHLCLPETVGKTSCRHSTNVVLQKTLESSLKED
                     TKNASETLGCRRLQPEEYFKSMTSSTVKSPSDSHPMGKRSPRGDLKTDTEESKVSCRR
                     IIPMTGKRVWPLYSCARITAECWKKTSLSDLNDSLPGSLGNVRQHDFLMHQTNQTHLP
                     DSKRLQPSLIERTIESSSKEVYDSELSSLSSVSSVEPTLLDIKETIPHDKKTKLEEPS
                     RNGTEVVSSATEDIQLSNITQILTGNKKKKGNLSKLNLTVAPQESQEANNCANKTVHR
                     KACITKQTLVAPDLVKILNTGRLTNFKIPLLKNKTGKRGEVSARSSEREAYSPLELLD
                     SLSGVEAKQNRNKENICTTSGPQSLNIHSVTPGQTSSHTFYNKNSCTSPSFTKKGYDN
                     KTCNHISETGNTISNKESLSIKIENNTFSCDLGYMEQSSFCSKKQEAFVPISSEISGR
                     KMTKSISELKLGFPDILKAYEDDVLLIDVIQDDPELFGISSEGDLSFASEVSKISQEP
                     RVSEEHPSADFKHRHLPGKKEPGDLSKEVALLDPGLLKLEICPSLSAAKEPQHDPKGA
                     AISLEATEETVISENLEDLSEQARASDSDTKCVSSDKATVVEEQENTHEVCKSKDSRS
                     VEAVSTECHLALGPNTLCSSAPPLTLSSHQDVAPAPWTNDFRFPGRYSVLQLQNPETC
                     EIFKREKNFGVFQKPLGLMIPHRYCKLHFNTLRGCERAQCKFVHVPEQGDEKICMDVF
                     KKYIRVNEQRLLHRAAYIFLEYYRKFPPGIHFSLQVLNDLLISLLKHCLLKEVFQVVQ
                     LSIMAKMLPALKILLKIFEYVAAMKLRNAVPALIEIFCKFIEAGMIPDPEHLNYIVKL
                     LHQAQASQQEISAVLEAKSRLQVRQLRKNWTCDLDSALSEVENCKEKGDWTKLGNLYI
                     SIKMGCEEFADFQRFCACVAETLTEDYKEERPGVPFCEFAETVSKDPQYSEVDKTLLG
                     RIGISAVYFYHRLLLWSKGRKVLDILYELKIHFTSLKGLTGPEKIAPRCQIVNVAAEI
                     FIKSGSLDGAIWVLRESEWITSTPLWPCDRADVLHRHNLLCAIAHEILGKNLYKQTFE
                     VLRNLPGFQNSQEAMGVSQSSLLFNELLDACIESNSLGISSSVADFMVAKSIPIDFSF
                     LRRLITSLGRSCLWLKARAHYKSALSLGCYPPLEGNVYRKLLLVPSYLSEIEMLLAIE
                     IFLVSNASSIQSPGAPTQVLQIVLKRCEESKPRSKDDYQAAVERLIMAARISDPKLFI
                     KHMTVNINKEQVYSLEHCSAVKWLKENMKWAGKVWLFTNH"
     exon            1170..3597
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            3598..3662
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            3663..3787
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            3788..3852
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            3853..3986
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            3987..4072
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4073..4198
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4199..4262
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4263..4414
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4415..4507
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4508..4623
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4624..4690
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4691..4865
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4866..4966
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            4967..5132
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            5133..5297
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            5298..5501
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            5502..5685
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
     exon            5686..5971
                     /gene="Topaz1"
                     /gene_synonym="RGD1563398"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 accaccagat ccacaatgtt ttccactgta gaacactttt cttctacaag cgacaaaact
       61 gattaaatat tcatgaacgg acacagtaga ccgggtccaa aataacacat aaggttaaac
      121 tccattccaa tcgttaagca atggaggctt gtgaagggtc aagatgtggc gtaccaggac
      181 cctctttcaa tggagaggca tggcctggca acctggtcaa acttgattga actgatacaa
      241 gtatggagac atcaataaaa ttagaagcat gatgttgtag gtcaactgtc tgagagccag
      301 agccacacta acgggaaagg gacctttaac aaagaaagaa agtagagcca agttgatttg
      361 gtaaatctgt atgcaaggaa tccagacggg cagctagaag cttctgccca acaacaccat
      421 agaagcaact tttacagaaa taaatgatat tttgcatgtc agcagctagg gtacctctga
      481 gctatctgga taaacgtgaa ggtaggtatt aagccaaagt gggctcccgg gagtgtagga
      541 gagcagttag aagccactgg tagacaacca ttgtcagggt gttgaggggt ggctgctaag
      601 agaaggagcc caggcacctc cataagtcca ggcctggagg agggtgagga ggcccaagga
      661 ggcaccatca caaacctgtg cagtgaggcc ctgcctgagg tgagatcctg tcacctccgg
      721 gtgcagcctg ggcccttcga gggagcatgt ggacgggcgg gctgaccacg aggccctcag
      781 ccggttgccc ccagccgagc ccaggccgtc cacttccgct tcctgttgcg tcgggtacag
      841 ggtccgaagc caggccaggc cagggtgggc agtagcctgt gtcctgcagc gggagcagcg
      901 gccctagggc gtctgggctt tccagagagg ctgcgtgggc ggccacgggc ggatgcggcc
      961 gccaacaacg cccccagtcc ccaccacggc gccagggcgt caaggcgcca ccgggggcct
     1021 gagaaagcga ggccttcgac tgacgccaga gccaggcgag gggggaggct gcagcctgga
     1081 ggccaggggg cgcgaggagg agagcaggca gaagcggagg atggtggccc aggcttctgg
     1141 gagagaagag acagaaggtg acaagttggc caaagagaat ggaaaagtca ctgaagcccc
     1201 aagtgatgag ccacagccag ggactgacct ggtaagaaag acatcaataa ccaattcgga
     1261 atctttgcaa acagtggagt gcagtgaatt tcaaagtatg gctttcttac agtctttggc
     1321 taaggaagaa ttggtagaag gtattaagag aagaattcaa attaaaaaat gtaaaagctc
     1381 agaaaatcca cctctcaaaa taactaaaaa tgaggcaaca caaaatatta tggttgaatc
     1441 acaagatgaa ctgttcaaga atacaccaaa atattcttgt aacagcttat cacccggagt
     1501 agaaaaaaat tgcagttttg aatcacatga tttcagtttc ctccattctg aaggttgtaa
     1561 taataaaaac ggctttgagg atgagcctca tggtgtgtgt ctacatgcag aagagaactc
     1621 tttgaagtca aagaaagaaa accttaggaa tcttgcagag aaggatgaca caaaaactac
     1681 taagttctta aaaactgaaa aaaatgtaat agccagtaag ttactgcttg aagaaagtca
     1741 tttataccaa aataaaaaca atggcttgac ttcttgcctt caaagtgaaa agaacaaata
     1801 ttcagtagag gagaacaaca ctgggagaaa acacaggaaa aagatgaagt tatctgaaaa
     1861 agaagaaaaa ggtatcgatc ttactttgtc taatgtgtgt aacaattctg agttggtgct
     1921 acaagaacac caaataggta tggaagggaa agaaacagag accttagaac ataaaaaaag
     1981 ttttctaaaa gctttaagaa aaatgaacca taatacactc cctccagtgg accatttgtg
     2041 tctcccagaa acagtgggga aaacaagttg tagacattcc acaaatgttg tgcttcagaa
     2101 aacccttgaa tcaagtttga aagaggatac aaaaaatgct tcagagacct taggatgcag
     2161 aaggctgcag ccagaagaat actttaaatc aatgacaagc tctacggtga aatcacctag
     2221 tgacagccat cctatgggaa agagatctcc acggggagat ttgaaaactg acactgaaga
     2281 gtcaaaggtt agctgtcgta gaataatacc aatgactggt aaaagggttt ggcctcttta
     2341 ttcttgtgct agaataactg ccgagtgttg gaagaagact tccttgtcag atttaaatga
     2401 ctcacttcca gggtctctgg gaaatgttag gcaacatgat tttctaatgc accaaacgaa
     2461 ccagactcac ttacctgact ccaaacggtt acaaccatcc ttaatagaaa gaaccatcga
     2521 gtcctcgagt aaagaagtgt atgattctga gttaagtagc ttgtcttcag tttcttcagt
     2581 agaacctact ttgttggata taaaggaaac tataccccat gataaaaaga caaagttaga
     2641 ggaacccagc cgaaatggga cagaagtagt ttctagtgct accgaagaca tccagttaag
     2701 taatataact caaatcttaa caggaaataa gaaaaagaaa gggaatttat caaaacttaa
     2761 tttaacagtg gcaccccaag agagccagga agcaaataac tgtgcaaata aaactgttca
     2821 tcgaaaagct tgtattacta agcaaacact tgtggctccg gacttggtta aaatattaaa
     2881 cacaggacgg ctgactaatt ttaaaatccc tttgctgaag aacaagacag gaaaaagagg
     2941 agaagtaagt gccagatcat ctgaaagaga ggcttatagt cccctagagc tacttgacag
     3001 tttatctgga gtagaggcaa aacaaaatag gaataaggaa aatatctgta caacttcagg
     3061 acctcagtct ttgaatatac atagtgtaac tccagggcaa accagttctc acacgttcta
     3121 caataagaat tcctgcactt ctccaagctt tacaaagaaa ggttatgata ataaaacatg
     3181 caatcacatc tctgaaacag gaaatactat ttcgaataag gagtctcttt ctattaaaat
     3241 tgaaaataat actttttctt gtgatcttgg gtatatggag caaagttcct tctgctctaa
     3301 gaaacaagaa gcatttgtgc caatttcctc agaaattagt ggtaggaaaa tgactaaaag
     3361 catttcagaa ctcaaattgg ggtttccaga tattcttaaa gcatatgaag atgatgtcct
     3421 cttgattgat gtaattcaag atgacccaga gctctttgga atctccagtg aaggggatct
     3481 ctcctttgct tcagaagtct ccaagataag ccaggagccc agagtatctg aagagcaccc
     3541 atcagcagac tttaagcaca ggcaccttcc agggaaaaaa gaaccaggcg atttgagtaa
     3601 agaagttgcc ttgctggacc ctggattgct gaaactggaa atctgtcctt ccttgtcagc
     3661 agcaaaggag cctcagcatg atcctaaagg ggcagccatc tccttagaag ctactgagga
     3721 gactgttata agtgaaaacc tagaagacct cagtgaacaa gcacgagctt cagactcaga
     3781 cacaaagtgc gtaagttcag acaaggcaac tgttgtggaa gaacaagaga acactcatga
     3841 agtttgcaaa agcaaagatt ccagaagtgt ggaggctgtg tctactgagt gtcacttagc
     3901 cctgggcccc aacaccctgt gctcatcagc gcctcctttg actctgagca gtcatcaaga
     3961 tgtagcgcca gcaccctgga cgaacgattt cagatttcca ggaagatatt ctgtcctaca
     4021 actgcagaat cctgaaactt gtgaaatatt taaaagggaa aaaaattttg gggtgttcca
     4081 gaagccctta ggattgatga taccccacag atactgcaag cttcatttta acacattgcg
     4141 tggctgtgag cgagcacagt gcaagtttgt ccatgtgcct gagcaggggg atgaaaagat
     4201 ctgcatggat gtgtttaaga agtacatacg tgtcaatgag cagcgtttgc tgcaccgagc
     4261 agcatacata tttctggaat actacagaaa gtttccccca gggatacact tcagtttaca
     4321 agtgctaaat gaccttttga tttctttact caagcattgc ttattgaaag aagtcttcca
     4381 ggtagtgcag ctcagcataa tggctaaaat gctgcctgct ctgaaaatat tactaaaaat
     4441 atttgagtat gtggcagcta tgaagctaag gaatgctgta cctgctttaa ttgagatttt
     4501 ttgcaagttc attgaggctg ggatgatacc tgacccagag cacttgaact acattgttaa
     4561 gcttttacac caagcacagg catcccaaca agaaatatct gcagttctgg aagccaaatc
     4621 gaggttgcaa gtgaggcagc tgagaaagaa ctggacgtgt gacttagact cggccttaag
     4681 tgaagtggag aattgtaaag aaaagggtga ctggaccaaa ttgggaaacc tgtacattag
     4741 cataaaaatg ggctgtgaag aatttgcaga tttccagaga ttctgtgcct gtgttgctga
     4801 aacactcaca gaagattata aagaagaaag gccaggtgtt cccttttgtg aatttgctga
     4861 aacagttagc aaagatccgc agtacagtga ggtggataag actttgttgg gaaggatcgg
     4921 aataagtgct gtgtacttct accacagact gttgctgtgg tctaagggaa ggaaggtctt
     4981 agatatacta tatgagctaa aaatacattt tacaagttta aaaggactta caggacctga
     5041 aaaaatagca ccaagatgtc aaattgtaaa cgttgcagca gagattttta tcaaaagtgg
     5101 gagcctagat ggtgccattt gggtactgag ggaatcggag tggataacca gcacaccgct
     5161 ttggccttgc gacagagcgg atgtgcttca tcgtcacaac ttgctctgcg ccatagcgca
     5221 tgagatcctg ggcaagaatc tgtacaaaca gacatttgag gtcttgcgga accttccagg
     5281 ctttcagaac tctcaagaag caatgggggt gtcccagtcc agccttctct ttaatgaact
     5341 cctggatgcc tgcatagaaa gtaacagtct tggcatatca tcttctgtag cagacttcat
     5401 ggttgcaaag agcatcccga ttgacttttc cttcctcagg agactgataa cgtccttagg
     5461 aaggagctgt ttgtggctca aagccagagc ccactacaaa agtgctcttt cactgggttg
     5521 ctacccacca ttagagggaa acgtataccg gaaacttcta ctggttcctt cttatttatc
     5581 tgagattgaa atgcttttag ctatcgagat atttctggtg tctaacgcta gtagtattca
     5641 gagcccagga gctcccaccc aggtgctgca gatcgttttg aaaagatgtg aagaaagcaa
     5701 acctcgaagc aaggacgatt atcaagctgc agtggaaaga ctgatcatgg ctgctcggat
     5761 atccgacccc aagcttttca tcaagcacat gaccgtcaac attaacaagg agcaggtgta
     5821 cagtctggag cactgctctg ccgtgaaatg gctgaaagag aatatgaagt gggctggaaa
     5881 ggtttggctt ttcactaacc attagttaat aaagggttgt tgttgggttt tctaagttca
     5941 agtaatcatt gttgaaaata aaagaataaa a
//
