LOCUS       NM_001399550            4775 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus target of myb1 like 2 membrane trafficking
            protein (Tom1l2), transcript variant 2, mRNA.
ACCESSION   NM_001399550
VERSION     NM_001399550.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4775)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   2  (bases 1 to 4775)
  AUTHORS   Katoh,Y., Imakagura,H., Futatsumori,M. and Nakayama,K.
  TITLE     Recruitment of clathrin onto endosomes by the Tom1-Tollip complex
  JOURNAL   Biochem Biophys Res Commun 341 (1), 143-149 (2006)
   PUBMED   16412388
REFERENCE   3  (bases 1 to 4775)
  AUTHORS   Franco,M., Furstoss,O., Simon,V., Benistant,C., Hong,W.J. and
            Roche,S.
  TITLE     The adaptor protein Tom1L1 is a negative regulator of Src mitogenic
            signaling induced by growth factors
  JOURNAL   Mol Cell Biol 26 (5), 1932-1947 (2006)
   PUBMED   16479011
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000010.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMEA5760383, SAMEA5760476
                              [ECO:0000350]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-128               JAXUCZ010000010.1  45657394-45657521   c
            129-217             JAXUCZ010000010.1  45589699-45589787   c
            218-352             JAXUCZ010000010.1  45588540-45588674   c
            353-431             JAXUCZ010000010.1  45583092-45583170   c
            432-581             JAXUCZ010000010.1  45578603-45578752   c
            582-716             JAXUCZ010000010.1  45571417-45571551   c
            717-875             JAXUCZ010000010.1  45569830-45569988   c
            876-992             JAXUCZ010000010.1  45567090-45567206   c
            993-1126            JAXUCZ010000010.1  45557163-45557296   c
            1127-1175           JAXUCZ010000010.1  45554005-45554053   c
            1176-1299           JAXUCZ010000010.1  45553425-45553548   c
            1300-1417           JAXUCZ010000010.1  45550811-45550928   c
            1418-1493           JAXUCZ010000010.1  45549900-45549975   c
            1494-1553           JAXUCZ010000010.1  45541564-45541623   c
            1554-1590           JAXUCZ010000010.1  45539623-45539659   c
            1591-4775           JAXUCZ010000010.1  45535548-45538732   c
FEATURES             Location/Qualifiers
     source          1..4775
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="10"
                     /map="10q22"
     gene            1..4775
                     /gene="Tom1l2"
                     /note="target of myb1 like 2 membrane trafficking protein"
                     /db_xref="GeneID:360537"
                     /db_xref="RGD:1306728"
     exon            1..128
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            129..217
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     CDS             165..1739
                     /gene="Tom1l2"
                     /note="isoform 2 is encoded by transcript variant 2;
                     TOM1-like protein 2; target of myb1-like 2"
                     /codon_start=1
                     /product="TOM1-like protein 2 isoform 2"
                     /protein_id="NP_001386479.1"
                     /db_xref="GeneID:360537"
                     /db_xref="RGD:1306728"
                     /translation="MMGAEFGSAEIKARLGGRAPYSRRNIKQFLSDFTEKATDGSLQS
                     EDWTLNMEICDIINETEEGPKDAIRALKKRLSGNRNYREVMLALTVLETCVKNCGHRF
                     HLLVANRDFIDSVLVRIISPKNNPPTIVQDKVLALIQAWADAFRSSPDLTGVVHIYEE
                     LKRKGIEFPMADLDALSPIHTPQRSVPEMDPAATIPRSQLQPRTTAGSYSSPPAAPYS
                     TLQAPALSVTGPITANSEQIARLRSELDIVRGNTKVMSEMLTEMVPGQEDSSDLELLQ
                     ELNRTCRAMQHRIVELISRVSNEEVTEELLHVNDDLNNVFLRYERFERYRSGRSVQNA
                     SNGVLSEVTEDNLIDLGPGSPAVVSPMVGSTAPPSSLSSQLAGLDLGTESVSGTLSSL
                     QQCKPQDGFDMFAQTRGNSLAEQRKTVTYEDPQAVGGLASALDNRKQSSEMIPVAQPS
                     VMDDIEVWLRTDLKGDDLEEGVTSEEFDKFLEERAKAAETVPDLPSPPTEAPAPASNT
                     SNRKKPERSEDALFAL"
     exon            218..352
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            353..431
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            432..581
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            582..716
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            717..875
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            876..992
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            993..1126
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1127..1175
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..1299
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1300..1417
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1418..1493
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1494..1553
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1554..1590
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
     exon            1591..4775
                     /gene="Tom1l2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtcagggca gagcgcagcg cgggcagcgg agacccgtgg cacacaggcg tccgggctgg
       61 aacgaggccc gccgagatgg agttcctgct ggggaatccg ttcagcaccc ctgtagggca
      121 gtgtcttggt tgccttttta ttctgttgtt tgtgtcttta atgcatgatg ggggcagagt
      181 ttggtagtgc tgagatcaaa gccaggcttg ggggaagggc cccatattcc aggagaaata
      241 taaagcagtt tctttctgat ttcacagaga aggcaacaga tggctccctg cagagcgagg
      301 actggacact gaacatggag atctgtgaca tcatcaatga gacagaagaa gggccaaagg
      361 atgccatccg agctctgaag aagcggctca gtgggaaccg gaactacaga gaagtgatgc
      421 tggccctgac agtgctggag acttgtgtga agaactgtgg ccatcgcttt cacctccttg
      481 tagccaaccg agacttcatt gacagtgttc tggtcagaat tatctctccc aagaataacc
      541 ctcccaccat cgtccaggac aaagtgcttg ctctaattca ggcatgggca gacgccttta
      601 ggagcagtcc tgacctcact ggtgttgtac acatctatga agaactgaag aggaagggga
      661 ttgagttccc catggcagac ttggacgctc tgtctcctat ccacacaccc cagcggagtg
      721 tcccagaaat ggatccagct gccaccattc ccaggtccca gttacagccc aggacaactg
      781 ctggctcgta ttcttcacct cctgcagctc cctactctac tctacaggcc ccggctctga
      841 gtgtgacggg ccccatcaca gccaattcag aacagattgc taggctgcgc agtgagctgg
      901 acattgttcg gggaaacaca aaagtcatgt ctgagatgtt aacagaaatg gtccctgggc
      961 aggaggattc ttctgatctg gaactactac aggagttgaa cagaacctgc cgagccatgc
     1021 agcaccgcat agtggagctc atctcccgag tgtccaatga ggaggtcacc gaggagctgc
     1081 tgcacgtcaa cgatgacctc aacaatgtct tcctccgcta tgagaggttc gagaggtacc
     1141 ggtctggccg atccgttcag aatgccagca atggagtact aagtgaagtt actgaagaca
     1201 acttaataga cctgggccca ggctctcccg ctgtggtgag ccccatggtg ggaagcacgg
     1261 cacccccatc ttctctctcc tcccaactcg caggcttgga cttggggaca gagagtgtca
     1321 gtggcaccct cagttcactt cagcagtgca agccacaaga tggttttgac atgtttgccc
     1381 agaccagagg aaactccttg gctgaacagc gaaagacggt cacctatgag gatccccagg
     1441 ctgttggagg actcgcttct gcactagaca atcggaaaca gagctcagaa atgattcccg
     1501 ttgcgcagcc ctctgtcatg gacgacattg aggtgtggct caggacagac ctgaagggtg
     1561 acgacctaga agagggtgtc acgagtgaag agtttgataa gttcctggaa gaaagagcca
     1621 aagctgcaga aacagttcca gacctgccct cacccccaac agaggcccct gcaccagcct
     1681 caaacacttc aaaccggaag aagccagagc ggtctgagga tgcgctcttt gctctgtgag
     1741 ctgtcctgtg gtctgccgcg ccctggcagg tcactgctga ctctcccagt ggacactggg
     1801 cactggccac tcccccagcc tgcatacctg tatctccatg gaaatgccac tgtgtttgca
     1861 cccaggccac cctggtcagg agcaactttg ccaccttctc tctgggtggc aactgcagca
     1921 ctgaccagag gtcctgtcct ccctcccccc gagggccctc gtggccttcg gtcttcccag
     1981 aaagaaccag tggcacagcg ccaggcaggg tagccccttg acactttctg gtcagaactc
     2041 ctgaactgac cctctcatct ccccttcctg cttctgccta gctccatggc ttccttcagg
     2101 tgagacactg ctccactgga cccccttctt ccatcaagga ttctgagaaa gcagggctca
     2161 agcgtttgta actacagact tggtttctct ccttgaactg tgtggtacct gtggcactta
     2221 gtgtgtctgt acttgagtgg gttctgtggt tactaccttg aagggccctc atgtccctgg
     2281 ccccttctcc atcagtcgac tgccaggcct gggaccaaga cagggacctg tggctcttgg
     2341 tgtgacagca gctgtgaggg cagcatgtgc cccgcagatg gtagacggct tactccaggc
     2401 acggcatgca cactcacatt catacccggc cctggtgtct acagagggtt atttgctaaa
     2461 gcaacatgac tttaatgcat cccatgacta gacttggtct tcaacagcct ccgcaagcta
     2521 tctctaggcc cagaagaagg tagctatggg ctgtgcctgg aggttccaga tgaccaggag
     2581 ccatactcca gtcctctcct ctccctgaca tggcctcagc cttcatggct gtccccacct
     2641 cacatatctc tagccaccaa ttcattctga agcttgctaa cagcctcagt ctgagcaaat
     2701 gagagctggc aatgcccggc gggtctggca aggccttatc tggcaggacc tacggaggat
     2761 gtcattcagg cttgcaaagg catccaggaa gcccctcctg cagggagctc agttgacctg
     2821 ctgaatgccc agacctctct gagcatctgt ctcacctcca ccctccattc aggacccttg
     2881 gccaaccaga acttctctca gtgtttctca agggcagagc cctcaaaggc tggcctggct
     2941 gctaaggctt ctgacggctt gtcacatcag aggcggccag ggagctcagt gtacctgaaa
     3001 gcttggcctt tggcacagtt ctagaagggt tgtctgtgag agtcagctat acacagccta
     3061 caagagttgg acatgtagga aatagcaacc aggccagcat ctctgaatta agaggctgcc
     3121 cctgtttatg gatgacatag aaagggagat aggcttccat cagggagaga gcctgatggg
     3181 ggtccccaac aaggctgttc ctagtaccag tgtccagagc tgtcctctga cctcctgact
     3241 ccagctgctg ggtctgactg aagctgggct gctgtggggg cagcaggtac tcaaggactc
     3301 ccaccagcca tcaagaggct acctctctgg ctgggaccag cccagctagt ggcttggttt
     3361 gtgttcttca catcatgtct agaggtagtc tgccttatct gtgggctgaa gtgacatgtg
     3421 cctgaggcct ttaccagaag caagactggg cctgggggtc tgaggggcct gagggaggtt
     3481 cacctcttgt gagctgtcct gtcctgagga ctctttcctg cctcttcccc accatctgtg
     3541 ggtaaagtcc ttagaagctg ggccctctca agccagcagt ctctacaagt gttagaaatc
     3601 acagatagag tgtgtactta attacactaa attatcgccg ggactcctca taagcactaa
     3661 ttacacctga ttataggtta aaatatttat tttgtcaaaa tattttcttg aggatgtatt
     3721 taaccttttt ttgttcattg tgtgctgaag tgtgaagact gcttcttcct acctttttgg
     3781 ccatcaggca gcagcgaagg agcgtctccg ggtgccctag agtgacctct gcccaggtac
     3841 taagaaggca gactggagtt gggccgagag tcaccaactc atttatctgt gcacgggaca
     3901 tgggggcttg gagccaaaag ggcttcttgg tagctgtggc cccggccagc ttccacttac
     3961 tctgtcagcc cctcagtgtg agagactgtg acttggctcg ttaccctcgt cctacccacc
     4021 tagcccacgc tgtctgccac tacactgctc agccaggaaa gtggtggctg gaccctccgt
     4081 ggcccagggc agtgagctcc tttgttccac cacaaagctc ccctttccac tgtcctctgg
     4141 ctgatggcct ctcagatggc gcaggatagg tactctgggg accaggtggt cctaggtggc
     4201 tgggagggca gagtggggct tttgttcctg cctggccagt ctgcagcctc cctgtgttct
     4261 gctgtaggga tgcctgggtc tccctgtgtg ctcagccaca caggaggcca ataggggagc
     4321 atgtctccac ttggagatcc tccctttgtg gccatctgga acctgcttag cccagtgcgc
     4381 atccccagcc cttcacgttc atggggtcta agctaggctt cccctagctc ccaagaataa
     4441 ctgtcaatcc tctgtcctga ctgctccctc ctgccacact catgccctca ggctctctgg
     4501 gagagctggg tagtttcttc ctaaagtttg cacttccttt gtgaggatct gaggatcttt
     4561 ggagctgctg aaaagatggt gttgagtttg ttattctgtt gtctcacgag tcagattctt
     4621 gtccctgtcc tgtttctgtg ggtagagctg cttctggagg gtggctcaga gtgacaacta
     4681 ttgtgtctcc ctaccccact ggttctgctt ccaaacactg tctctaattt gtgttcttgc
     4741 atgtaaagta ctccacaata aatagttgaa ccagc
//
