LOCUS       NM_001107607            6163 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus tankyrase 2 (Tnks2), mRNA.
ACCESSION   NM_001107607 XM_001080123 XM_220047
VERSION     NM_001107607.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 6163)
  AUTHORS   Kuusela,S., Wang,H., Wasik,A.A., Suleiman,H. and Lehtonen,S.
  TITLE     Tankyrase inhibition aggravates kidney injury in the absence of
            CD2AP
  JOURNAL   Cell Death Dis 7 (7), e2302 (2016)
   PUBMED   27441654
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6163)
  AUTHORS   Kulak,O., Chen,H., Holohan,B., Wu,X., He,H., Borek,D.,
            Otwinowski,Z., Yamaguchi,K., Garofalo,L.A., Ma,Z., Wright,W.,
            Chen,C., Shay,J.W., Zhang,X. and Lum,L.
  TITLE     Disruption of Wnt/beta-Catenin Signaling and Telomeric Shortening
            Are Inextricable Consequences of Tankyrase Inhibition in Human
            Cells
  JOURNAL   Mol Cell Biol 35 (14), 2425-2435 (2015)
   PUBMED   25939383
REFERENCE   3  (bases 1 to 6163)
  AUTHORS   Barkauskaite,E., Jankevicius,G. and Ahel,I.
  TITLE     Structures and Mechanisms of Enzymes Employed in the Synthesis and
            Degradation of PARP-Dependent Protein ADP-Ribosylation
  JOURNAL   Mol Cell 58 (6), 935-946 (2015)
   PUBMED   26091342
  REMARK    Review article
REFERENCE   4  (bases 1 to 6163)
  AUTHORS   Vyas,S., Matic,I., Uchima,L., Rood,J., Zaja,R., Hay,R.T., Ahel,I.
            and Chang,P.
  TITLE     Family-wide analysis of poly(ADP-ribose) polymerase activity
  JOURNAL   Nat Commun 5, 4426 (2014)
   PUBMED   25043379
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 6163)
  AUTHORS   Cerone,M.A., Burgess,D.J., Naceur-Lombardelli,C., Lord,C.J. and
            Ashworth,A.
  TITLE     High-throughput RNAi screening reveals novel regulators of
            telomerase
  JOURNAL   Cancer Res 71 (9), 3328-3340 (2011)
   PUBMED   21531765
REFERENCE   6  (bases 1 to 6163)
  AUTHORS   Hsiao,S.J., Poitras,M.F., Cook,B.D., Liu,Y. and Smith,S.
  TITLE     Tankyrase 2 poly(ADP-ribose) polymerase domain-deleted mice exhibit
            growth defects but have normal telomere length and capping
  JOURNAL   Mol Cell Biol 26 (6), 2044-2054 (2006)
   PUBMED   16507985
REFERENCE   7  (bases 1 to 6163)
  AUTHORS   Chiang,Y.J., Nguyen,M.L., Gurunathan,S., Kaminker,P.,
            Tessarollo,L., Campisi,J. and Hodes,R.J.
  TITLE     Generation and characterization of telomere length maintenance in
            tankyrase 2-deficient mice
  JOURNAL   Mol Cell Biol 26 (6), 2037-2043 (2006)
   PUBMED   16507984
REFERENCE   8  (bases 1 to 6163)
  AUTHORS   Cook,B.D., Dynek,J.N., Chang,W., Shostak,G. and Smith,S.
  TITLE     Role for the related poly(ADP-Ribose) polymerases tankyrase 1 and 2
            at human telomeres
  JOURNAL   Mol Cell Biol 22 (1), 332-342 (2002)
   PUBMED   11739745
REFERENCE   9  (bases 1 to 6163)
  AUTHORS   Kaminker,P.G., Kim,S.H., Taylor,R.D., Zebarjadian,Y., Funk,W.D.,
            Morin,G.B., Yaswen,P. and Campisi,J.
  TITLE     TANK2, a new TRF1-associated poly(ADP-ribose) polymerase, causes
            rapid induction of cell death upon overexpression
  JOURNAL   J Biol Chem 276 (38), 35891-35899 (2001)
   PUBMED   11454873
REFERENCE   10 (bases 1 to 6163)
  AUTHORS   Lyons,R.J., Deane,R., Lynch,D.K., Ye,Z.S., Sanderson,G.M.,
            Eyre,H.J., Sutherland,G.R. and Daly,R.J.
  TITLE     Identification of a novel human tankyrase through its interaction
            with the adaptor protein Grb14
  JOURNAL   J Biol Chem 276 (20), 17172-17180 (2001)
   PUBMED   11278563
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000001.1.
            
            On Jan 9, 2008 this sequence version replaced NM_001107607.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.741940.1,
                                           SRR26643297.5208.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-199               JAXUCZ010000001.1  243980746-243980944
            200-424             JAXUCZ010000001.1  243988255-243988479
            425-520             JAXUCZ010000001.1  243990610-243990705
            521-557             JAXUCZ010000001.1  243992760-243992796
            558-633             JAXUCZ010000001.1  243993641-243993716
            634-728             JAXUCZ010000001.1  243993961-243994055
            729-795             JAXUCZ010000001.1  243996227-243996293
            796-982             JAXUCZ010000001.1  243998692-243998878
            983-1104            JAXUCZ010000001.1  243999894-244000015
            1105-1196           JAXUCZ010000001.1  244003000-244003091
            1197-1275           JAXUCZ010000001.1  244003182-244003260
            1276-1447           JAXUCZ010000001.1  244006307-244006478
            1448-1527           JAXUCZ010000001.1  244007406-244007485
            1528-1673           JAXUCZ010000001.1  244011442-244011587
            1674-1839           JAXUCZ010000001.1  244012332-244012497
            1840-2059           JAXUCZ010000001.1  244013523-244013742
            2060-2169           JAXUCZ010000001.1  244014983-244015092
            2170-2358           JAXUCZ010000001.1  244016302-244016490
            2359-2611           JAXUCZ010000001.1  244019479-244019731
            2612-2694           JAXUCZ010000001.1  244020618-244020700
            2695-2815           JAXUCZ010000001.1  244022110-244022230
            2816-2913           JAXUCZ010000001.1  244024833-244024930
            2914-2988           JAXUCZ010000001.1  244026204-244026278
            2989-3094           JAXUCZ010000001.1  244027920-244028025
            3095-3281           JAXUCZ010000001.1  244028835-244029021
            3282-3438           JAXUCZ010000001.1  244029978-244030134
            3439-6163           JAXUCZ010000001.1  244030905-244033629
FEATURES             Location/Qualifiers
     source          1..6163
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="1"
                     /map="1q53"
     gene            1..6163
                     /gene="Tnks2"
                     /note="tankyrase 2"
                     /db_xref="GeneID:309512"
                     /db_xref="RGD:1305026"
     CDS             1..3501
                     /gene="Tnks2"
                     /EC_number="2.4.2.30"
                     /note="tankyrase, TRF1-interacting ankyrin-related
                     ADP-ribose polymerase 2; tankyrase-2-like"
                     /codon_start=1
                     /product="poly [ADP-ribose] polymerase tankyrase-2"
                     /protein_id="NP_001101077.2"
                     /db_xref="GeneID:309512"
                     /db_xref="RGD:1305026"
                     /translation="MSGRRCAGGGAACSSAVAEAVEPSARELFEACRNGDVERVKRLV
                     TPEKVNSRDTAGRKSTPLHFAAGFGRKDVVEYLLQNGANVQARDDGGLIPLHNACSFG
                     HAEVVNLLLQHGADPNARDNWNYTPLHEAAIKGKIDVCIVLLQHGAEPTIRNTDGRTA
                     LDLADPSAKAVLTGDYKKDELLESARSGNEEKMMALLTPLNVNCHASDGRKSTPLHLA
                     AGYNRVKIVQLLLQHGADVHAKDKGDLVPLHNACSYGHYEVTELLVKHGACVNAMDLW
                     QFTPLHEAASKNRVEVCSLLLSYGADPTLLNCHNKSAIDLAPTAQLKERLSYEFKGHS
                     LLQAAREADVTRIKKHLSLEMVNFKHPQTHETALHCAAASPYPKRKQICELLLRKGAN
                     TNEKTKEFLTPLHVASENAHNDVVEVVVKHEAKVNALDSLGQTSLHRAAHCGHLQTCR
                     LLLSYGCDPNIISLQGLTALQMGNENVQQLLQEGVSLGHSEADRQLLEAAKAGDVETV
                     KKLCTVQSVNCRDIEGRQSTPLHFAAGYNRVSVVEYLLQHGADVHAKDKGGLVPLHNA
                     CSYGHYEVAELLVKHGAVVNVADLWKFTPLHEAAAKGKYEICKLLLQHGADPTKKNRD
                     GNTPLDLVKDGDTDIQDLLRGDAALLDAAKKGCLARVKKLSSPDNVNCRDTQGRHSTP
                     LHLAAGYNNLEVAEYLLQHGADVNAQDKGGLIPLHNAASYGHVDVAALLIKYNACVNA
                     TDKWAFTPLHEAAQKGRTQLCALLLAHGADPTLKNQEGQTPLDLVSADDVSALLTAAM
                     PPSALPTCYKPQVLSGVRSPGATADALSSGPSSPSSLSAASSLDNLAGSFSELSAVVS
                     SSTTEGATGLERKEDSGIDFSITQFIRNLGLEHLMDIFEREQITLDVLVEMGHKELKE
                     IGISAYGHRHRLIKGVERLISGQQGLNPYLTLNNSGSGTILIDLSPDDKEFQSVEEEM
                     QSTVREHRDGGHAGGIFNRYSILKIQKVCNKKLWERYTHRRKEVSEENHNHANERMLF
                     HGSPFVNAIIHKGFDERHAYIGGMFGAGIYFAENSSKSNQYVYGIGGGTGCPVHKDRS
                     CYICHRQLLFCRVTLGKSFLQFSAMKMAHSPPGHHSVTGRPSVNGLALAEYVIYRGEQ
                     AYPEYLITYQIVRPEGMGDG"
     exon            1..199
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            200..424
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            425..520
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            521..557
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            558..633
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            634..728
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            729..795
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            796..982
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            983..1104
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            1105..1196
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            1197..1275
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            1276..1447
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            1448..1527
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            1528..1673
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            1674..1839
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            1840..2059
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            2060..2169
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            2170..2358
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            2359..2611
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            2612..2694
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            2695..2815
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            2816..2913
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            2914..2988
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            2989..3094
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            3095..3281
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            3282..3438
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
     exon            3439..6163
                     /gene="Tnks2"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgtctggcc gccgctgcgc cggcgggggc gcggcctgct cgagcgcggt ggcggaggcc
       61 gtagagccgt ccgcccgcga actgttcgag gcttgccgca acggggacgt agagcgagtg
      121 aagaggctgg tgacgcccga gaaggtgaac agccgcgaca cggcgggcag gaagtccacc
      181 ccgctccact tcgccgcagg ttttggtcgg aaggatgtag ttgagtatct gcttcagaat
      241 ggtgcaaatg tgcaagcccg tgatgacgga ggtcttattc ctcttcataa cgcatgctct
      301 tttggtcatg ctgaagtagt caatcttctt ttgcaacatg gtgcagaccc aaatgcccgg
      361 gataattgga attatactcc tctccatgaa gctgcaatta aaggaaaaat tgatgtttgc
      421 attgtgcttt tacagcatgg agctgagcca accatccgaa atacagatgg aaggacagca
      481 ttggatttag cagacccatc cgccaaagct gttctgaccg gtgactataa gaaagatgaa
      541 ctcttggaaa gtgccaggag tggcaatgag gagaaaatga tggctctgct tacaccactg
      601 aatgtcaact gccatgcaag tgatggcaga aagtcaactc cattgcattt ggcagcagga
      661 tacaacagag taaaaattgt ccaactgtta ctgcaacatg gagcagatgt ccatgctaag
      721 gataaaggtg atctggtacc attacacaac gcctgctcct acggtcatta tgaagtaact
      781 gaacttctgg tcaagcatgg tgcctgtgta aatgcaatgg atttgtggca atttactcct
      841 cttcatgagg cagcttctaa gaacagggtt gaagtgtgtt ctcttctcct aagttatggg
      901 gcagatccaa ccctgctgaa ctgtcacaat aagagtgcta tagacctggc ccccacagca
      961 cagctgaagg aaagattatc gtatgagttt aaaggccatt cattgctgca agctgcacga
     1021 gaagctgatg ttacaagaat caaaaaacat ctttctctgg aaatggtgaa tttcaaacat
     1081 cctcaaacac atgaaacagc actgcattgt gctgctgcgt ctccatatcc taaaagaaag
     1141 caaatatgcg aactgctgct aagaaaggga gcaaacacca acgaaaagac gaaagaattc
     1201 ttgactcctc tgcacgtggc ttctgagaat gctcacaatg atgttgttga agtagtggtg
     1261 aaacacgaag caaaggttaa tgctttggac agtcttggac agacatcctt acacagagct
     1321 gcacactgtg gtcatctgca gacttgccgc cttctcctga gctatgggtg cgatccaaac
     1381 atcatctccc ttcagggtct cactgccttg caaatgggaa atgagaacgt gcagcagctg
     1441 cttcaagagg gcgtctcact aggtcactca gaggcagaca gacagttgct ggaggctgca
     1501 aaggctggtg atgtagaaac tgtaaagaaa ctctgtactg ttcagagtgt caactgcaga
     1561 gacattgaag gacggcagtc aaccccactc cattttgcag ctgggtacaa cagagtgtct
     1621 gtggtagagt atctcctgca gcacggagct gacgtacatg ctaaagacaa aggaggtctt
     1681 gttcctttgc acaatgcatg ttcttacgga cactatgaag ttgcagaact tcttgtcaag
     1741 catggagcag tagttaatgt agctgactta tggaagttca cacctctaca tgaagctgca
     1801 gcaaaaggaa aatatgaaat atgcaaactt ctgctccagc atggtgcaga ccctacaaag
     1861 aaaaatagag atggtaatac tcctctggat ctcgttaaag atggagacac agatattcaa
     1921 gatctactta gaggagatgc agccttacta gatgctgcca agaagggttg tttagccaga
     1981 gtgaagaaat tatcttcacc tgataatgta aattgccgtg atacccaagg tcgacattct
     2041 acacctttgc atttggcagc tggttataat aatttggaag ttgctgaata tttgttgcaa
     2101 catggagctg atgtgaatgc ccaggacaaa ggaggactca ttccattaca taatgcagca
     2161 tcatatggac atgtagacgt agcagcttta ctgataaagt acaatgcgtg tgtcaatgcc
     2221 acggacaaat gggctttcac accgttacat gaagcagccc aaaagggacg gacacagctt
     2281 tgtgctttat tgttggccca tggagctgat cctactctta aaaatcaaga aggacaaaca
     2341 cctttagact tagtttcagc agatgatgtc agcgctctct tgacagcagc catgcccccc
     2401 tctgctctgc ctacgtgcta taaacctcaa gtgctcagtg gcgtgaggag ccccggagcc
     2461 actgcagacg ccctgtcttc aggtccgtcc agtccatcca gcctttctgc agccagcagc
     2521 ctcgacaacc tcgctggcag tttttctgaa ctgtctgcag tagttagctc aagtacaacg
     2581 gaaggtgcta ccggtttgga aagaaaagag gattcaggaa tagattttag tataactcag
     2641 ttcataagga accttggact tgagcattta atggacatat ttgagcgaga acagatcacc
     2701 ttggatgtac tggttgagat gggccacaaa gagctgaaag agattggaat cagtgcgtat
     2761 ggacatcgac acaggctcat taaaggggtc gaaagactga tctctggaca acaaggtctt
     2821 aatccatatt taactctaaa caactctggt agtggaacaa ttctcataga tctgtctcct
     2881 gatgataaag aatttcagtc tgtggaagaa gagatgcaaa gtactgttcg agagcacagg
     2941 gatggaggtc acgcaggcgg catcttcaac agatacagta ttctcaagat tcagaaggtt
     3001 tgtaacaaga aattgtggga aagatataca caccggagaa aagaagtttc tgaagaaaac
     3061 cacaaccatg caaatgaaag aatgttattt catgggtctc cctttgtgaa tgcgataatc
     3121 cataagggct ttgatgagag gcacgcctac atagggggca tgtttggagc tgggatctat
     3181 tttgctgaga actcttccaa aagcaatcag tatgtgtatg ggattggagg tggcactgga
     3241 tgtccagttc acaaagacag atcgtgttac atttgtcaca ggcagctgct cttttgtcgc
     3301 gtgaccttgg gaaagtcttt cctgcagttc agtgcaatga aaatggcgca ctctcctccc
     3361 ggccatcact cagtcactgg ccggcccagt gtgaatggcc tagctttagc tgaatatgtt
     3421 atttacagag gagagcaggc ttaccctgaa tatctaatta cttaccagat tgtaaggcct
     3481 gaaggtatgg gtgatggctg aaaccagttc tcccaaacat agtgtcctga agcgctgacg
     3541 gcctcttaag tttcactcct tggcgggaaa agattcatcc tgactacagg cctgtggcag
     3601 aaacaaaatg tgaaagacac ctcatgttgt gacttggtga agctttaaca gtgtacagtg
     3661 tttccgagtg tttcctgtct cagcacttta acagatgcca ttccaggttc aactgggtct
     3721 gtctgtccta aattataaac agttaacttg aatcttttat acgtcatgca ttgattctaa
     3781 caaaaatggt aatccctcaa cagaactcat tttactaatc agtactgtgt tctttaaaac
     3841 acagcattta cactgaagac agtttcattt gtaaaatgta aataagagct tttgtactag
     3901 cccggtattt atttacattg ctttgtacta taaactgttc tagagctgca ggtttacaga
     3961 gtattttcat atgtgttgct catctgtgtt tcatctgtcg tcacctgagt gatcgctacg
     4021 ttggattcca gaggctgctc agttgctaac agagttagtg gggagacatc aacttaataa
     4081 gttcaatttg ctgatgaaag aatttctcta tcaatagaaa tctttcacgt aagaatttta
     4141 taaatactct gggaatttta ttggtgatgc ctttgtgtct acagggcaca cgttccagag
     4201 agctctggtg tgaagtgatg ggggacttgt ggctagagaa gcttttcaat ggccttaaac
     4261 tctgggtcct gcttgagaga ggtctgaggt tctcaacatc agagcagagc ttccaccaag
     4321 ctttcagaat gctaagcccc cacttctcaa cacttagtgc tctgatcatg aattgtgagt
     4381 ggaagttaca tttggtactg gggaaggcaa tcatgggtat ttccaatcag atctaattac
     4441 cttaaatcta aaatggaggg gtagggatag caagtgggag tggatagttt ttttactttc
     4501 taagttttct tgatcttatg gttatgttta tagccagtgt atttatcacg agtaaacaca
     4561 acccaaaatc ataggtgtga gtgtatgtgt ctgtgggtaa cctctggaaa gggcaagccc
     4621 tgcgcttcct acttctgtca aggcattcgg cccagttgga aaaacactgt cacaggctta
     4681 agttcagtat ggcagctgtg gaagaagtca ctttccatga aaggccattt ttactgttct
     4741 ctaacgtatc tctaatgtaa gccttacact tactatctta tcttgcattg cacagagatc
     4801 tgtcttactg cacggcagtg cactcagaaa tcagagattt ttacccacct aagcttttgt
     4861 gaatgaggat gtcctcttca ctctctttac cactttatct ttgttttata tttgatttgg
     4921 tctcttaatt acctggtcct ttatacaaac ttgtacatag agttgctcga aagttaagct
     4981 taaccatcct atgagttaag agaattatat gtctggagtt gttcctaaga tgtgaattgt
     5041 ggtcaagggt taagaggtca aatcctaacc tggaaatgct tttatacagc tctctgctaa
     5101 ctacaaacat cctaaaacca tttcttgaat ataaaaggag tatgccaaat tttatataaa
     5161 attttcaggt tctgtaagct tctgggtttt atagttaaaa gataatgaaa ttaattgatg
     5221 gggtttatat ttacgtactt ctaaggttgg cctatgttac tctgtgtatg gatctggaat
     5281 tgtttttcat gtaaaatcat ggtctggtta tgagctgtgt tacctcctaa ccccattgct
     5341 tacgtgtttc cactgtggtc aatacgctgg catggcaatg tttattggga gctgggagtt
     5401 tgggggtgtg gtttagtgct ttgcatgaaa taccttactt tataatgatg aaattgcttt
     5461 ttcttttgcc ttgtgatttt tttttttgaa gtgaaattta gtttgtgtgt gtgtggtgat
     5521 ctgcccatcg gagtgtctcc ttgtatcaca ttccatgcct cacttaactc ttaataaact
     5581 gtttacttgt tttatgggta gcatggtaat tcattgagat tgcagtcaat cgttattgca
     5641 agagaacaga gtgtagtttt gagtctgatt gtgacagggt gcaacataaa tgtaaaatgt
     5701 tgaatgttgt ggccatactt aactcagttg cttcctgatg aaggtaacat gtgtctgggc
     5761 ggctacacca tctagtatga ctttggtagt ccttaaaatt cacccatgaa atcagtctgc
     5821 ttaacttata aagagaaata tatttttggt ttttatgtca taaaaacatt cttgataagt
     5881 ttccaaatcc cagttagtca tatttttttt ctctaaaagg aaaaaaaatt agtgtatttt
     5941 atatttccat atgctaatga cctgtatgta attagtcctt ggtgttccac aagaagagtc
     6001 tcatcgaagt cgatataagc tgctttaccc tcctgcttct tttaagatga tactgaagtg
     6061 tttgcttgct atttgctgag cgtgcatgcc cacgtatgat gtgttccaat tgtttgcagg
     6121 ttgaggcaag aaaacatgca aataaacttc ccaaacctcc taa
//
