LOCUS       NM_001319033            3939 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus TNF superfamily member 8 (Tnfsf8), mRNA.
ACCESSION   NM_001319033 XM_001064723 XM_003749957
VERSION     NM_001319033.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3939)
  AUTHORS   Premzl,M.
  TITLE     Comparative genomic analysis of eutherian tumor necrosis factor
            ligand genes
  JOURNAL   Immunogenetics 68 (2), 125-132 (2016)
   PUBMED   26646413
REFERENCE   2  (bases 1 to 3939)
  AUTHORS   Nishimura,H., Yajima,T., Muta,H., Podack,E.R., Tani,K. and
            Yoshikai,Y.
  TITLE     A novel role of CD30/CD30 ligand signaling in the generation of
            long-lived memory CD8+ T cells
  JOURNAL   J Immunol 175 (7), 4627-4634 (2005)
   PUBMED   16177108
REFERENCE   3  (bases 1 to 3939)
  AUTHORS   Rossi,F.M., Degan,M., Mazzocut-Zecchin,L., Di Francia,R.,
            Aldinucci,D., Pinto,A. and Gattei,V.
  TITLE     CD30L up-regulates CD30 and IL-4 expression by T cells
  JOURNAL   FEBS Lett 508 (3), 418-422 (2001)
   PUBMED   11728464
REFERENCE   4  (bases 1 to 3939)
  AUTHORS   Geertsen,S., Trifaro,J.M. and Quik,M.
  TITLE     Phorbol esters and K+ up-regulate alpha-bungarotoxin binding sites
            in cultured chromaffin cells through a related mechanism
  JOURNAL   Neurosci Lett 148 (1-2), 207-210 (1992)
   PUBMED   1300497
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Aug 29, 2022 this sequence version replaced NM_001319033.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643292.21928.1,
                                           SRR26643284.7348.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680419, SAMN11044071
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-490               JAXUCZ010000005.1  82292369-82292858   c
            491-533             JAXUCZ010000005.1  82284237-82284279   c
            534-605             JAXUCZ010000005.1  82272087-82272158   c
            606-3939            JAXUCZ010000005.1  82266436-82269769   c
FEATURES             Location/Qualifiers
     source          1..3939
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q24"
     gene            1..3939
                     /gene="Tnfsf8"
                     /gene_synonym="Tnlg3a"
                     /note="TNF superfamily member 8"
                     /db_xref="GeneID:683163"
                     /db_xref="RGD:1590403"
     exon            1..490
                     /gene="Tnfsf8"
                     /gene_synonym="Tnlg3a"
                     /inference="alignment:Splign:2.1.0"
     CDS             287..1000
                     /gene="Tnfsf8"
                     /gene_synonym="Tnlg3a"
                     /note="CD30 antigen ligand; tumor necrosis factor (ligand)
                     superfamily, member 8; tumor necrosis factor ligand 3a;
                     tumor necrosis factor superfamily member 8"
                     /codon_start=1
                     /product="tumor necrosis factor ligand superfamily member
                     8"
                     /protein_id="NP_001305962.1"
                     /db_xref="GeneID:683163"
                     /db_xref="RGD:1590403"
                     /translation="MEPGLQQARSRGAPSPDPAMQVPPGSADSLWRSTRPWRTRSYFY
                     LSTIALVCLVVALAIILVLVVQKKDSTPKTTESVPLKGGNCSEDLLCTLKRTPSKKSW
                     AYLQVSKHLNSAKLSWNQDGTIHGLVYQDGNLVVQFPGWYFIICQLQFLVQCSNHSMD
                     LTLQLVINSKIKKQALVTVCESGVQGKNIYHNLSQFLLHYLQVNSTISVRVDNFQYVD
                     TNTFPLDNVLSVFLYSSSD"
     exon            491..533
                     /gene="Tnfsf8"
                     /gene_synonym="Tnlg3a"
                     /inference="alignment:Splign:2.1.0"
     exon            534..605
                     /gene="Tnfsf8"
                     /gene_synonym="Tnlg3a"
                     /inference="alignment:Splign:2.1.0"
     exon            606..3939
                     /gene="Tnfsf8"
                     /gene_synonym="Tnlg3a"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctccttcc taccaccctc tgacatcaac cttcgtctct tgctacaatt tctctgcact
       61 caaattaatc ccggacgatg aaaaatgaac ctctccccca cccttgcagc cacccttcgc
      121 ctcacgcccc cagagaagag tttctccatc cggcaactgg tgaaggcttt tttccaagtc
      181 acatgatcca ggatgcaggg gaaaatcctt cttggaacag agctgggtgc agaatcgaat
      241 cagatgagga gagataaggt gtgatgtggg acagactata taaagcatgg agccagggct
      301 gcaacaagca cgcagccgtg gggccccttc ccctgaccca gccatgcagg tgccgcccgg
      361 ctcggcagac agcctctgga gaagcacgag gccctggaga acccgcagct acttctacct
      421 cagcaccatc gcactggtgt gccttgtcgt ggcactggca atcattctgg tcctggtagt
      481 ccagaaaaag gactccactc caaaaacaac tgagtcggtc ccccttaaag gaggaaattg
      541 ctcagaggac ctcttatgta ccctgaaaag gactccatcc aagaagtcat gggcctacct
      601 ccaagtgtcg aaacatctca acagtgccaa actatcatgg aaccaagacg gtaccatcca
      661 cggactcgta taccaggatg ggaacctggt ggtccaattc ccaggctggt acttcatcat
      721 ttgtcaactg caatttctcg tgcagtgctc aaatcattcc atggacctga cactgcagct
      781 cgtcatcaat tccaaaatca aaaagcaggc actggtaaca gtgtgtgagt ctggagttca
      841 aggcaagaac atctaccata atctctctca gttcttgctg cattacctac aggtcaactc
      901 taccatatct gtccgggtgg ataatttcca gtatgtggat acaaacactt tccctcttga
      961 taacgtgctg tccgtcttcc tatatagtag ctcagactga atagctactc ttaaccttta
     1021 tgaaaatgct gtctaccata cagtacttca tctgtccaaa catgggacaa agaaaatatc
     1081 aggacaactc aaactaagca tgtgagttag tgtacttctc cttctgtcct atggaaagac
     1141 acaagcccaa ggtttagaag gcgaggtctg catcagatgc acagccaggc agggtgcagt
     1201 gtgtggacag agacctacat aggcactaaa aggggtcaag ttgtctcaat ataaccacta
     1261 attcactgac cttgagccat ttttcctcct cctggaactc ggggtctgaa tctgaaaaag
     1321 taggagatgg gatttacatt tccccaacac tttcttcctc aacttagaag ataagactgt
     1381 tgagctgagc ttctcaagag atcaaaaagc ctcccatggc atgaggaaac tgatgaacca
     1441 gtaatgtctg tctgccggtc atctcagcaa gtcataagga tttccatgct gccgtgtaat
     1501 atgatactcc aacctctttg taatgggcca ggtaatcctg tctctcacct aggggagtag
     1561 cttctgccat ctcctgagat gtatgtggtg gcattttctg cctcaaatcc attctatgtg
     1621 cagtttttaa gtaaccaccc ccaaatttgt tgacaatgcg aaccttgaaa gtgggaagaa
     1681 ctcctggaca gcaaacatta acagcttctc ctgaccagag aggccacgca gttctcttag
     1741 actcgtcaag gttgctgttt ctatagcatt gtgggagaca gacttctgac aaatcatctg
     1801 atatgcggac ccctgggagt tatacttcac tgaggaaagc aagtcctgtc agtgctgcat
     1861 gagaggatgg agtaaaatag gagctcttct gagggaaagg agaaaaacaa tggttcaaaa
     1921 agaggctcga aatatttaaa aggaaaagaa gaaaatatag cttttctgat gtgagaggaa
     1981 cccagagaaa caaaactgaa aacgaagagt aactcttgtc aacctccgct taggtgtcct
     2041 cctctctgat tattggaaaa gtagttgcct ggtacaggtc aggttcttgc atggtcaaat
     2101 agaatcaggt gtggagactg ccatgctgga cactaaggag acctgtcata tgtgtgctgt
     2161 actcaaatga ggggcaagtg attctgagat taaatcaaca catgcattct agaggaacct
     2221 atatgagagc caagcaaatg ttctcccctt tcagattcga agtcaagaaa gactccagtt
     2281 catttttctg aggctgtcct ctaggtagaa gtacctgcct tttgtactat gatttgatct
     2341 tttcctaata acagtctctg tcacgctgtg ctcagaaagc caaccactga agatagggtc
     2401 acttcatcta aaaaagtgaa atgtagcaaa atggaaacaa atatagccaa caattattaa
     2461 taagtcagct ggagtggaca taagaagtgg acagtccagg tgtttaaaac taaactatga
     2521 tatttttgag gattaacttg ccccccgtgg gactttctgg catatctgta ataatatatt
     2581 tttcattgat gtgacagagt gcttgataga tacaactgaa gaaaaagatt gattttggat
     2641 cacactttaa gaaaagctac agtctacaat ggccagaagg caaggcagca ggaatgtggg
     2701 gggatggtca cactgggtcc gcagtcatga agtagagaga gatggacgtt ggtatgcatc
     2761 tctcttcccc cttttctcca tttattcagt ctgcaattct agtcaataag acagtgctgc
     2821 ccaccttcag aataggtcta caacatgtag ttgaatctct caagagacac tatcttaaaa
     2881 tcagccaggc atgtgtgtcc cagtagattc caaatcctgt caacttgaca atgaagatta
     2941 attatcacca catacgtgca agcacatcat ttttctaact ggatgcttag gctacctaaa
     3001 acccatattt gcttagtgaa aattcagtga atttatatgc catgcactca caaacttgat
     3061 gaaaattgtc tttgaaaagt ttgttttagt tgatgaaatc ttccacctct ggtgtgaggt
     3121 cagttagccc tggtgggttt cccattgtgt agaaatccag agaacaccag tccctatcca
     3181 gtcctcaagg acttcatcca gcccctgacc ccagctctgc tctttctcat caggctttct
     3241 tggacttccc acggctttta ggaaaggctt caggtcacat ctctccagcc ccacactgaa
     3301 acagcccccg caccaaggca gtcctctgcc ctcctctatg tgccccagcc acttcatctc
     3361 catcttctgt agatttggcc cataactgag tcacagaaga gggcaagagc tatgttacaa
     3421 ccctcagaac caaaggagtt taggatcaag ccaatactat ttttagatta aaaataataa
     3481 aacttactgt ttagtttgaa cctatacata tataggtgta catgtgtgtg catatatgca
     3541 catatgtgca tgtgcatgtg tgcatatttt tccagtcatg ttttacatat catctgctta
     3601 gtctagttca gggaattggg aatttcaaag cttgtatatg cttatattta tttttaatta
     3661 agaagtgaaa ataatatttt tcctaggctt catcagctta tttaattatt attaatattt
     3721 ttccagattt ccatctgctt cattttttta aaaaaaatgg agatagagct tagccacact
     3781 cttccatccc ctactccctc tccaaggagt cataactgct gtctggaaat ctgtgcctgc
     3841 ttttcattta cataaactca cattggtttt ctaaataaga atatatggaa caattttgtg
     3901 tgccttttaa attttttaat aaaagatata ctttatatg
//
