LOCUS       NM_019135               3386 bp    mRNA    linear   ROD 05-AUG-2024
DEFINITION  Rattus norvegicus TNF receptor superfamily member 8 (Tnfrsf8),
            mRNA.
ACCESSION   NM_019135 XM_346753
VERSION     NM_019135.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3386)
  AUTHORS   Buschow,S.I., van Balkom,B.W., Aalberts,M., Heck,A.J., Wauben,M.
            and Stoorvogel,W.
  TITLE     MHC class II-associated proteins in B-cell exosomes and potential
            functional implications for exosome biogenesis
  JOURNAL   Immunol Cell Biol 88 (8), 851-856 (2010)
   PUBMED   20458337
REFERENCE   2  (bases 1 to 3386)
  AUTHORS   Smith,A.J., Karpova,Y., D'Agostino,R. Jr., Willingham,M. and
            Kulik,G.
  TITLE     Expression of the Bcl-2 protein BAD promotes prostate cancer growth
  JOURNAL   PLoS One 4 (7), e6224 (2009)
   PUBMED   19593445
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3386)
  AUTHORS   Nishikori,M., Ohno,H., Haga,H. and Uchiyama,T.
  TITLE     Stimulation of CD30 in anaplastic large cell lymphoma leads to
            production of nuclear factor-kappaB p52, which is associated with
            hyperphosphorylated Bcl-3
  JOURNAL   Cancer Sci 96 (8), 487-497 (2005)
   PUBMED   16108830
REFERENCE   4  (bases 1 to 3386)
  AUTHORS   Kwitek,A.E., Gullings-Handley,J., Yu,J., Carlos,D.C., Orlebeke,K.,
            Nie,J., Eckert,J., Lemke,A., Andrae,J.W., Bromberg,S., Pasko,D.,
            Chen,D., Scheetz,T.E., Casavant,T.L., Soares,M.B., Sheffield,V.C.,
            Tonellato,P.J. and Jacob,H.J.
  TITLE     High-density rat radiation hybrid maps containing over 24,000
            SSLPs, genes, and ESTs provide a direct link to the rat genome
            sequence
  JOURNAL   Genome Res 14 (4), 750-757 (2004)
   PUBMED   15060019
REFERENCE   5  (bases 1 to 3386)
  AUTHORS   Kurts,C., Carbone,F.R., Krummel,M.F., Koch,K.M., Miller,J.F. and
            Heath,W.R.
  TITLE     Signalling through CD30 protects against autoimmune diabetes
            mediated by CD8 T cells
  JOURNAL   Nature 398 (6725), 341-344 (1999)
   PUBMED   10192335
  REMARK    Erratum:[Nature 2000 Sep 21;407(6802):413]
REFERENCE   6  (bases 1 to 3386)
  AUTHORS   Aizawa,S., Nakano,H., Ishida,T., Horie,R., Nagai,M., Ito,K.,
            Yagita,H., Okumura,K., Inoue,J. and Watanabe,T.
  TITLE     Tumor necrosis factor receptor-associated factor (TRAF) 5 and TRAF2
            are involved in CD30-mediated NFkappaB activation
  JOURNAL   J Biol Chem 272 (4), 2042-2045 (1997)
   PUBMED   8999898
REFERENCE   7  (bases 1 to 3386)
  AUTHORS   Aizawa,S., Satoh,H., Horie,R., Ito,K., Choi,S.H., Takeuchi,H. and
            Watanabe,T.
  TITLE     Cloning and characterization of a cDNA for rat CD30 homolog and
            chromosomal assignment of the genomic gene
  JOURNAL   Gene 182 (1-2), 155-162 (1996)
   PUBMED   8982082
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Nov 30, 2020 this sequence version replaced NM_019135.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: D42117.1, SRR26643292.24206.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-147               JAXUCZ010000005.1  162451474-162451620 c
            148-235             JAXUCZ010000005.1  162439156-162439243 c
            236-352             JAXUCZ010000005.1  162434875-162434991 c
            353-484             JAXUCZ010000005.1  162432891-162433022 c
            485-575             JAXUCZ010000005.1  162429266-162429356 c
            576-742             JAXUCZ010000005.1  162428711-162428877 c
            743-833             JAXUCZ010000005.1  162426318-162426408 c
            834-931             JAXUCZ010000005.1  162425879-162425976 c
            932-1030            JAXUCZ010000005.1  162423170-162423268 c
            1031-1084           JAXUCZ010000005.1  162422993-162423046 c
            1085-1110           JAXUCZ010000005.1  162415489-162415514 c
            1111-1321           JAXUCZ010000005.1  162413428-162413638 c
            1322-3386           JAXUCZ010000005.1  162406387-162408451 c
FEATURES             Location/Qualifiers
     source          1..3386
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..3386
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /note="TNF receptor superfamily member 8"
                     /db_xref="GeneID:25069"
                     /db_xref="RGD:3879"
     exon            1..147
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     CDS             85..1566
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /note="CD30L receptor; lymphocyte activation antigen CD30;
                     tumor necrosis factor superfamily, member CD30; Tumor
                     necrosis factor superfamily member 8; tumor necrosis
                     factor receptor superfamily, member 8"
                     /codon_start=1
                     /product="tumor necrosis factor receptor superfamily
                     member 8 precursor"
                     /protein_id="NP_062008.2"
                     /db_xref="GeneID:25069"
                     /db_xref="RGD:3879"
                     /translation="MSILLKAAGLLFLGMLQAFPKDRPLDTTCTGDLSYYPGEAARNC
                     CYQCPSGLSPTQPCPQGPAHCQKQCDPDYYINEDRKCTACVTCLPGLVEKAPCSGNSP
                     RICECQPGMYCSTPAVNSCARCSEKTVVKFPDTAEKNTICDLPSPGSGPNGSNPDDCK
                     TLTSHTTPQAIPTLESPANDSVRSLLPKQVTDFVNEGATKLVKVPESSSSKASMPSPD
                     PGNAEMNMTLKLPPPGTVPDISTSENSMEPASTASTLSLLVDARTSSRMQPTSPLSTG
                     TPFLDPGSMLFWVAMVVLLVGSASFLLCYWKACRRRFQRKFHLNYLQQTFQPKMEQVD
                     SCPTEKLTQLQRSGSVTDSSAGHTLSPLSPPAVETGASVGTACLETLPLLDDSITGNS
                     FAPREPPEPRVSTEHTNNRIEKIYIMKADTVIVGSVKTEVPEGRAPVGSTESELEAEL
                     EVDHTPHYPEQETEPPLGSCTEVMFSVEEGGKEDHEPTTVSEK"
     exon            148..235
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            236..352
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            353..484
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            485..575
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            576..742
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            743..833
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            834..931
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            932..1030
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            1031..1084
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1110
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            1111..1321
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
     exon            1322..3386
                     /gene="Tnfrsf8"
                     /gene_synonym="Cd30"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggcgcagcca cattagaagt gatttcacca cggagagtca gggtgccggc aggtggccag
       61 gcgctggaga cgcgggaagc caagatgagc atcctactca aggcagccgg gttgctgttc
      121 ctggggatgc ttcaagcctt cccaaaggat cgaccactgg acactacctg taccggagac
      181 ctcagctact accccgggga ggctgccagg aactgctgtt accagtgccc ctcagggttg
      241 tctcctacac agccatgccc acagggccct gcccactgcc agaagcagtg tgatcctgac
      301 tactacatca acgaagacag gaagtgcaca gcctgcgtga cctgtttgcc aggcctcgtg
      361 gagaaggctc catgttctgg gaactctcct cgaatctgtg agtgtcagcc cggcatgtac
      421 tgctccacac cagctgtcaa ttcctgtgcc cgatgttctg aaaagacggt tgtcaagttc
      481 ccagacacag cagaaaagaa cactatctgt gatctgccct ccccaggatc tggccccaat
      541 ggctccaatc cagacgactg caaaacactt actagccata ccactcctca ggccatacct
      601 actctagaat ctccagccaa tgacagtgtg aggagcttgc tgccaaaaca ggtcactgac
      661 tttgtgaacg aaggtgctac taagctggtg aaggttcctg agtcttcctc ttccaaggca
      721 agcatgccta gtccagatcc aggtaatgca gagatgaata tgaccttgaa gcttccacct
      781 ccagggacag tccctgacat cagtacttca gaaaacagca tggagcctgc cagtaccgcc
      841 tccaccctaa gcctcttggt agatgcccgg accagcagca ggatgcagcc tacatctccc
      901 ttgtccacag gaacaccgtt tctggatcca gggtccatgc tcttctgggt ggccatggtg
      961 gtgctgctgg ttggctctgc ctccttcctc ctgtgttact ggaaggcctg caggaggcgg
     1021 ttccagcgga agtttcacct gaactatcta cagcagacct tccagcccaa gatggagcag
     1081 gtagattcct gtcctactga aaagctaact cagctgcaga gaagtgggtc agtgacagat
     1141 tccagcgctg gacacacgtt gagcccactg agccctccag ctgtagagac tggtgccagt
     1201 gttggaaccg cctgcctgga gaccctgccg ctgctggatg acagcataac tgggaactct
     1261 tttgctccca gagaacctcc agagccacgg gtatccaccg aacacaccaa caacaggatt
     1321 gagaaaatct acatcatgaa ggctgacaca gtgattgtgg gctcagtaaa aactgaagtc
     1381 cctgagggcc gggctccagt agggtctaca gagtctgagt tggaagctga actagaagtg
     1441 gaccataccc cccattaccc ggagcaggag acagaaccac ctctgggcag ctgcactgag
     1501 gtcatgttct ccgtggagga aggaggaaaa gaagaccatg agcccacaac tgtctctgag
     1561 aagtaacacc caatgttagc gggggctaga gtacagctga gtgttcagtt tgagatcagg
     1621 ttaatacctg ggaagctacc acggcttgaa ctgaagcccc ggcatccagg gtagcacaga
     1681 atgaagcctt cagctgctac caagaacact ggcccctgga ccccagcagt gcgcactcac
     1741 catcaggctg ttgtctactg ggggagaagc tacaggttgg gttccaagcc tccttgccca
     1801 cacccctgtg ccctgccttc tctccttggg tctcaagtga tggctttact gacatgctac
     1861 cagccttcag ctatacacat ggctccctgg aacagaacca acacctaatt gcttctactc
     1921 ctgaggaaga gggaagttaa aggatgaatg ctcatcatca ctggcacaat gatagcctgt
     1981 gcccatcaca cagggagggc gaaatgagac ccttctggca tggcctccct gttctgtgga
     2041 ctccctcagc agctgcagtg atcccaccca ctaaatgatg ctggagactc tactttgcca
     2101 caggagttcc tgtcatgtgg tgatgggagt actgtagtcc tggccgtcct taacacattg
     2161 tgcctctatc tgttctgccc tggaaatgaa gaagcattgt ccctaagcca ccaggatcag
     2221 gcctgacacc taggaggttg gagcctatct ttgaaggcac cctgctgctc acgctgcttg
     2281 ccataccctg cgcccactct gaggaggcag tgctgctgaa cttacctgaa gttccgcttt
     2341 taatgttttg ttttgttttt ttcctttcga ggtactgaga attgaaccca tggccttgtg
     2401 catgccagga aaaggttgca gggctgatca accccagcct agcatttcat actaagcact
     2461 aaaagctgct gtcactccca gcctggctca ctccctggca tttgcgtact cttgtaacaa
     2521 acgagcagcc aactggatga cacatctgct ctgtggcagc caggggactc tggacttacc
     2581 cttgggccag gcagggagaa ttctgtttac tcactagctg tttgctgtgt ggaggaagtt
     2641 gggaccctgt caagaatcac gaggggagtt tctgaaactg cttgaatcta tggggaaaag
     2701 ttggagtggc tgagtaccac cagaggcgtt aaatcacagt ctagatacta gccagaaggg
     2761 atgtgtgggg gctggatagt tgcccatttg tcttgtgcaa ggacacagta gatatgtggg
     2821 catgcatagt gatcccaaag ccatgtcaca atgaccacat ggatgccaca cttttggaag
     2881 atattgccca actttttctt cttcttcttt tttttttcta agatcttgtt ctgtatccta
     2941 gggtagattc gaacttgata tggctgaccc tgaacctgtg accctcctat cttaacttcc
     3001 caaggaagga caggcttcag ccactatgcc agactgccac acatttcaac aaagggacat
     3061 attcccttgc aaaagtagct cttcacacaa ttttttgacc ctctaaaaat ccctacgggc
     3121 ctgtaaaaat taatggattt gtgaggccga aaactgatca gagagatgag tagtgggagg
     3181 ccctgaacac aaagactgtc aggggtctgg tctattctct ctagacaggg ctgttctctt
     3241 tgtgcaaagc acccacagcc aagggcagga gcccatgacc agctgtgtgc cctttaaatc
     3301 tctccttgtc catctgggca gtcccttctt ccctgttcaa ggcctgccct ccaaggatgc
     3361 tgggaataaa ggatctctgc tcacaa
//
