LOCUS       NP_001131116             407 aa            linear   ROD 24-JUN-2024
DEFINITION  tumor necrosis factor receptor superfamily member 25 precursor
            [Rattus norvegicus].
ACCESSION   NP_001131116 XP_001076437 XP_575965
VERSION     NP_001131116.1
DBSOURCE    REFSEQ: accession NM_001137644.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (residues 1 to 407)
  AUTHORS   Migone,T.S., Zhang,J., Luo,X., Zhuang,L., Chen,C., Hu,B.,
            Hong,J.S., Perry,J.W., Chen,S.F., Zhou,J.X., Cho,Y.H., Ullrich,S.,
            Kanakaraj,P., Carrell,J., Boyd,E., Olsen,H.S., Hu,G., Pukac,L.,
            Liu,D., Ni,J., Kim,S., Gentz,R., Feng,P., Moore,P.A., Ruben,S.M.
            and Wei,P.
  TITLE     TL1A is a TNF-like ligand for DR3 and TR6/DcR3 and functions as a T
            cell costimulator
  JOURNAL   Immunity 16 (3), 479-492 (2002)
   PUBMED   11911831
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473968.1.
            
            On or before Nov 14, 2008 this sequence version replaced
            XP_575965.2, XP_001076437.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN06621351,
                              SAMN06680412 [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..407
                     /organism="Rattus norvegicus"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     Protein         1..407
                     /product="tumor necrosis factor receptor superfamily
                     member 25 precursor"
                     /note="tumor necrosis factor receptor superfamily, member
                     25"
                     /calculated_mol_wt=40823
     sig_peptide     1..30
                     /inference="COORDINATES: ab initio prediction:SignalP:6.0"
                     /calculated_mol_wt=3285
     Region          37..147
                     /region_name="TNFRSF25"
                     /note="tumor necrosis factor receptor superfamily member
                     25 (TNFRSF25), also known as death receptor 3 (DR3);
                     cd13420"
                     /db_xref="CDD:276925"
     Region          40..75
                     /region_name="CRD1"
                     /note="CRD1 [structural motif]"
                     /db_xref="CDD:276925"
     Region          78..120
                     /region_name="CRD2"
                     /note="CRD2 [structural motif]"
                     /db_xref="CDD:276925"
     Region          122..146
                     /region_name="CRD3"
                     /note="CRD3 [structural motif]"
                     /db_xref="CDD:276925"
     Region          324..400
                     /region_name="DD"
                     /note="Death Domain Superfamily of protein-protein
                     interaction domains; cl14633"
                     /db_xref="CDD:472698"
     CDS             1..407
                     /gene="Tnfrsf25"
                     /coded_by="NM_001137644.1:135..1358"
                     /db_xref="GeneID:500592"
                     /db_xref="RGD:1598206"
ORIGIN      
        1 meqrprgcvv eplflpslll llllllgghg qggtpgrcdc asepqkrygq lccrgcpkgq
       61 ymkapctepc gdssclpcpp gtflardshf ktdctrcqvc deealqvtle ncsaetdthc
      121 gcqsgwcvdc stepcgkssp fsctpcssye pttyrpcppg fyihgngcas cptsfssvcp
      181 kactavcgwk qmfwvqvllg asfllgtvli caycrwqpck pvvtadiagm etlaspqtth
      241 fsasdsahtl lpppgstgkv cttvqlvgnn wtpglsqtee vvcrqasqpw dqlpnrtlgp
      301 plvpplspap pagspaavlq pgpqlydvmd avparrwkef vrtlglreae ieaveveicr
      361 frdqqyemlk rwrqqqpagl gaiyaalerm glegcaedlr srlqrgp
//
