LOCUS       NM_001024349            1029 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus TNF receptor superfamily member 18 (Tnfrsf18),
            mRNA.
ACCESSION   NM_001024349 XM_575972
VERSION     NM_001024349.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1029)
  AUTHORS   Ghezeldasht,S.A., Sadeghian,H., Azarpazhooh,M.R., Shamsian,S.A.A.,
            Rafatpanah,H., Mahmoodi,M. and Rezaee,S.A.
  TITLE     Evaluation of T Regulatory Lymphocytes Transcription Factors in
            HTLV-1-Associated Myelopathy/Tropical Spastic Paraparesis (HAM/TSP)
            Patients
  JOURNAL   Appl Biochem Biotechnol 182 (4), 1403-1414 (2017)
   PUBMED   28101786
REFERENCE   2  (bases 1 to 1029)
  AUTHORS   Lacal,P.M., Petrillo,M.G., Ruffini,F., Muzi,A., Bianchini,R.,
            Ronchetti,S., Migliorati,G., Riccardi,C., Graziani,G. and
            Nocentini,G.
  TITLE     Glucocorticoid-induced tumor necrosis factor receptor
            family-related ligand triggering upregulates vascular cell adhesion
            molecule-1 and intercellular adhesion molecule-1 and promotes
            leukocyte adhesion
  JOURNAL   J Pharmacol Exp Ther 347 (1), 164-172 (2013)
   PUBMED   23892569
REFERENCE   3  (bases 1 to 1029)
  AUTHORS   Shi,Y.J., Yang,J. and Yang,W.
  TITLE     Mechanistic investigation of immunosuppression in patients with
            condyloma acuminata
  JOURNAL   Mol Med Rep 8 (2), 480-486 (2013)
   PUBMED   23754510
REFERENCE   4  (bases 1 to 1029)
  AUTHORS   Ramirez,E., Cartier,L., Rodriguez,L., Alberti,C. and
            Valenzuela,M.A.
  TITLE     In vivo fluctuation of Tax, Foxp3, CTLA-4, and GITR mRNA expression
            in CD4(+)CD25(+) T cells of patients with human T-lymphotropic
            virus type 1-associated myelopathy
  JOURNAL   Braz J Med Biol Res 43 (11), 1109-1115 (2010)
   PUBMED   20945034
REFERENCE   5  (bases 1 to 1029)
  AUTHORS   Chae,W.J., Henegariu,O., Lee,S.K. and Bothwell,A.L.
  TITLE     The mutant leucine-zipper domain impairs both dimerization and
            suppressive function of Foxp3 in T cells
  JOURNAL   Proc Natl Acad Sci U S A 103 (25), 9631-9636 (2006)
   PUBMED   16769892
REFERENCE   6  (bases 1 to 1029)
  AUTHORS   Fontenot,J.D., Rasmussen,J.P., Gavin,M.A. and Rudensky,A.Y.
  TITLE     A function for interleukin 2 in Foxp3-expressing regulatory T cells
  JOURNAL   Nat Immunol 6 (11), 1142-1151 (2005)
   PUBMED   16227984
  REMARK    Erratum:[Nat Immunol. 2006 Apr;7(4):427]
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            FM088311.1 and JAXUCZ010000005.1.
            
            On Sep 13, 2012 this sequence version replaced NM_001024349.1.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR23984936.977061.1,
                                           SRR26360186.1183768.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760476, SAMN06621351
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: downstream AUG is associated
                                                with N-terminal localization
                                                signal
            RefSeq Select criteria           :: based on conservation,
                                                expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-108               FM088311.1         1-108
            109-205             JAXUCZ010000005.1  171902088-171902184
            206-328             JAXUCZ010000005.1  171902984-171903106
            329-416             JAXUCZ010000005.1  171903637-171903724
            417-619             JAXUCZ010000005.1  171903898-171904100
            620-1029            JAXUCZ010000005.1  171904169-171904578
FEATURES             Location/Qualifiers
     source          1..1029
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..1029
                     /gene="Tnfrsf18"
                     /note="TNF receptor superfamily member 18"
                     /db_xref="GeneID:500598"
                     /db_xref="RGD:1565872"
     exon            1..205
                     /gene="Tnfrsf18"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..744
                     /gene="Tnfrsf18"
                     /note="tumor necrosis factor receptor superfamily, member
                     18"
                     /codon_start=1
                     /product="tumor necrosis factor receptor superfamily
                     member 18 precursor"
                     /protein_id="NP_001019520.2"
                     /db_xref="GeneID:500598"
                     /db_xref="RGD:1565872"
                     /translation="MGAWAMLYGVSLICVLDLGQQSIAEEPSCGPGRVRNGTGTNTRC
                     CSLCGPDKEDCPKGRCICVKPEYHCEDPQCKTCKHYPCQPGQRVESQGNIKFGFQCVD
                     CAMGTFSAGREGHCRLWTNCSQFGFLTVFPGNKTHNAVCIPEPLPTEQYGHLTVIFLV
                     MAACILFLTTVQLGLHIWQLRRQHTCPRDTQPLLEVQLPPAEDACSFQFPEEERGEQM
                     EEKCRLGDRWP"
     exon            206..328
                     /gene="Tnfrsf18"
                     /inference="alignment:Splign:2.1.0"
     exon            329..416
                     /gene="Tnfrsf18"
                     /inference="alignment:Splign:2.1.0"
     exon            417..619
                     /gene="Tnfrsf18"
                     /inference="alignment:Splign:2.1.0"
     exon            620..1029
                     /gene="Tnfrsf18"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atgttggagc gggaactcct gaaatcagcc aacagaagac tcgggagaag cactatggga
       61 gcatgggcca tgctgtatgg agtctcgctg atttgtgtgc tggacctagg tcagcagagc
      121 attgctgagg agcctagctg cggtcctggc agggtccgga atggaactgg cacgaacaca
      181 cgctgctgca gtctgtgtgg tccagacaag gaggactgtc caaaaggaag gtgcatatgt
      241 gtcaagcctg agtaccactg tgaagaccct cagtgcaaga cctgcaaaca ctacccctgc
      301 caaccaggcc agagggtgga gtctcaaggg aatattaagt ttggcttcca gtgcgttgac
      361 tgtgccatgg gtaccttctc tgcaggtcgt gagggtcact gcagactttg gaccaactgt
      421 tctcagtttg gatttctcac cgtgttcccc gggaacaaga cccacaatgc tgtgtgcatc
      481 ccggagccac tgcccactga gcaatatggc catttgactg tcatcttcct ggtcatggct
      541 gcatgcattc tcttcttaac cacagtccag ctcggcctgc acatatggca gctgaggagg
      601 caacacacgt gtccccgaga tacccagccg ctcctggagg tgcagttacc accagctgag
      661 gatgcttgca gcttccagtt tcctgaggag gaacgtgggg agcagatgga agaaaagtgt
      721 cgtctggggg accggtggcc atgaggcctg ttcttcctct gtgccccaag tcagactcta
      781 caagacttgc ccagaaatac ccttggtgag agcaggggct atgctctgcg tccttccctg
      841 ggcctggccc cactcccctg gacaatggcg gaagtgggtg tgagacggta gtggtgagtt
      901 acaactgagc cctgtggctg cctttctcat ttgccagctc tgtggagcag ggtctttggg
      961 ccctccaaga acaccaagtt tagcacaaga tcttatacaa gtggttttca ataaatactt
     1021 gtctagtaa
//
