LOCUS       NM_001015034            2089 bp    mRNA    linear   ROD 23-MAR-2023
DEFINITION  Rattus norvegicus TNF receptor superfamily member 14 (Tnfrsf14),
            mRNA.
ACCESSION   NM_001015034 XM_345616
VERSION     NM_001015034.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2089)
  AUTHORS   Zhu Y, Yao S, Augustine MM, Xu H, Wang J, Sun J, Broadwater M, Ruff
            W, Luo L, Zhu G, Tamada K and Chen L.
  TITLE     Neuron-specific SALM5 limits inflammation in the CNS via its
            interaction with HVEM
  JOURNAL   Sci Adv 2 (4), e1500637 (2016)
   PUBMED   27152329
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2089)
  AUTHORS   Shui JW, Larange A, Kim G, Vela JL, Zahner S, Cheroutre H and
            Kronenberg M.
  TITLE     HVEM signalling at mucosal barriers provides host defence against
            pathogenic bacteria
  JOURNAL   Nature 488 (7410), 222-225 (2012)
   PUBMED   22801499
REFERENCE   3  (bases 1 to 2089)
  AUTHORS   Kim HM, Jeong CS, Choi HS, Kawada T and Yu R.
  TITLE     LIGHT/TNFSF14 enhances adipose tissue inflammatory responses
            through its interaction with HVEM
  JOURNAL   FEBS Lett 585 (3), 579-584 (2011)
   PUBMED   21236258
REFERENCE   4  (bases 1 to 2089)
  AUTHORS   Dahl CP, Gullestad L, Fevang B, Holm AM, Landro L, Vinge LE, Fiane
            AE, Sandberg WJ, Otterdal K, Froland SS, Damas JK, Halvorsen B,
            Aukrust P, Oie E and Yndestad A.
  TITLE     Increased expression of LIGHT/TNFSF14 and its receptors in
            experimental and clinical heart failure
  JOURNAL   Eur J Heart Fail 10 (4), 352-359 (2008)
   PUBMED   18353719
REFERENCE   5  (bases 1 to 2089)
  AUTHORS   Cai G, Anumanthan A, Brown JA, Greenfield EA, Zhu B and Freeman GJ.
  TITLE     CD160 inhibits activation of human CD4+ T cells through interaction
            with herpesvirus entry mediator
  JOURNAL   Nat Immunol 9 (2), 176-185 (2008)
   PUBMED   18193050
  REMARK    Erratum:[Nat Immunol. 2008 May;9(5):567]
REFERENCE   6  (bases 1 to 2089)
  AUTHORS   Sedy JR, Gavrieli M, Potter KG, Hurchla MA, Lindsley RC, Hildner K,
            Scheu S, Pfeffer K, Ware CF, Murphy TL and Murphy KM.
  TITLE     B and T lymphocyte attenuator regulates T cell activation through
            interaction with herpesvirus entry mediator
  JOURNAL   Nat Immunol 6 (1), 90-98 (2005)
   PUBMED   15568026
REFERENCE   7  (bases 1 to 2089)
  AUTHORS   Lee WH, Kim SH, Lee Y, Lee BB, Kwon B, Song H, Kwon BS and Park JE.
  TITLE     Tumor necrosis factor receptor superfamily 14 is involved in
            atherogenesis by inducing proinflammatory cytokines and matrix
            metalloproteinases
  JOURNAL   Arterioscler Thromb Vasc Biol 21 (12), 2004-2010 (2001)
   PUBMED   11742877
REFERENCE   8  (bases 1 to 2089)
  AUTHORS   Zapata JM, Pawlowski K, Haas E, Ware CF, Godzik A and Reed JC.
  TITLE     A diverse family of proteins containing tumor necrosis factor
            receptor-associated factor domains
  JOURNAL   J Biol Chem 276 (26), 24242-24252 (2001)
   PUBMED   11279055
REFERENCE   9  (bases 1 to 2089)
  AUTHORS   Tamada K, Shimozaki K, Chapoval AI, Zhai Y, Su J, Chen SF, Hsieh
            SL, Nagata S, Ni J and Chen L.
  TITLE     LIGHT, a TNF-like molecule, costimulates T cell proliferation and
            is required for dendritic cell-mediated allogeneic T cell response
  JOURNAL   J Immunol 164 (8), 4105-4110 (2000)
   PUBMED   10754304
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC091202.1.
            
            On Apr 20, 2005 this sequence version replaced XM_345616.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC091202.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN06680416, SAMN06680429
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on conservation,
                                                expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2089
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q36"
     gene            1..2089
                     /gene="Tnfrsf14"
                     /note="TNF receptor superfamily member 14"
                     /db_xref="GeneID:366518"
                     /db_xref="RGD:1310115"
     exon            1..152
                     /gene="Tnfrsf14"
                     /inference="alignment:Splign:2.1.0"
     CDS             90..926
                     /gene="Tnfrsf14"
                     /note="tumor necrosis factor receptor superfamily member
                     14; tumor necrosis factor receptor superfamily, member 14
                     (herpesvirus entry mediator)"
                     /codon_start=1
                     /product="tumor necrosis factor receptor superfamily
                     member 14 precursor"
                     /protein_id="NP_001015034.1"
                     /db_xref="GeneID:366518"
                     /db_xref="RGD:1310115"
                     /translation="MEPLPGWESSPWSRADNTFRLVPCVFLLNLLQCISAQPLCRQEE
                     FSVGDECCPMCNPGYHVKQVCSEHTGTVCAPCPPQTYTAHANGLSKCLPCGVCDPDMG
                     LLTWQECSSWKDTVCRCISGYFCENQDGGACSTCLPHAACPPGQRVQKRGTYSHDTVC
                     ADCLTGTFSLGGTQEECLPWTKCSTFQREVKHGTSSTDTTCSFQTFYIVVVIVGVAIV
                     GAGVVVFLLRKQRQRHTSIVASELEAFQQEQQEDAIRFPVIEVGPSVTEEEAAFNCMN
                     SG"
     exon            153..261
                     /gene="Tnfrsf14"
                     /inference="alignment:Splign:2.1.0"
     exon            262..387
                     /gene="Tnfrsf14"
                     /inference="alignment:Splign:2.1.0"
     exon            388..543
                     /gene="Tnfrsf14"
                     /inference="alignment:Splign:2.1.0"
     exon            544..634
                     /gene="Tnfrsf14"
                     /inference="alignment:Splign:2.1.0"
     exon            635..795
                     /gene="Tnfrsf14"
                     /inference="alignment:Splign:2.1.0"
     exon            796..827
                     /gene="Tnfrsf14"
                     /inference="alignment:Splign:2.1.0"
     exon            828..2059
                     /gene="Tnfrsf14"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacttttagt tttagctggg gctcatgaga gtgtgtgagg aggtccaaag tccatggggc
       61 tcctggcctg cagtgtcttg attaagaaaa tggaacctct cccgggatgg gagtcgtcac
      121 cctggagccg ggcagacaac accttcaggc tggtgccgtg tgtcttcctt ttgaacttgt
      181 tgcagtgtat ctctgcccag cccttgtgca gacaggagga gttttctgtt ggggatgagt
      241 gctgccccat gtgcaatcca ggttaccatg tgaagcaggt ctgcagtgag catacaggca
      301 cagtgtgtgc cccctgtccc ccacagacct ataccgccca tgcgaatggc ctgagcaagt
      361 gtctgccctg cggagtctgt gatccagaca tgggcctgct gacctggcag gagtgctcca
      421 gctggaagga cactgtgtgc agatgcatct caggttactt ctgtgagaac caggatgggg
      481 gcgcctgttc cacatgcttg cctcacgccg cctgccctcc aggacagagg gtacagaaga
      541 gaggtactta cagccatgac actgtatgtg ctgactgcct gacaggaacc ttctcacttg
      601 gcgggactca ggaggaatgc ctgccctgga ccaagtgcag tacctttcaa cgggaagtaa
      661 aacatgggac cagcagcaca gacaccacct gctccttcca gaccttctac atcgtcgttg
      721 tgatagtggg agttgcgata gtgggagctg gggtagttgt attcctcctc cgcaagcaaa
      781 gacagcggca taccagcata gtggccagtg agctggaggc tttccagcag gagcaacaag
      841 aggacgccat caggtttcca gtcatcgagg ttggtccttc tgtgaccgag gaggaggcag
      901 ccttcaactg catgaattcg gggtgatgag acaccttgga gaccctgatg ggaagtttcc
      961 atatgccaga ggggcacggc agatgccctg ggctgctacg gcatcacatg gcaggggaga
     1021 tgttgccatg gcccagggtg tagcagttgc tttgtccttc ttagtgttaa atgggatcat
     1081 ctgcgcccat gcaaacgatc caaagtctgt atcagtgaca gttaccacag accctatgcc
     1141 ctacttccca aatcttccag acagcctgtc taaaccctag gcctttgacc gtcctggaaa
     1201 tgttaaaggc tgctcatcca gagggctgct gagcacggcc ttctggggtc agggtgcttg
     1261 cgatgagaca agaatatggc attggtggat tttattttga agtttctggg gctggaatct
     1321 tgcccatacc aggcaagtgc tttattcctg agctacattc ccaagactct ttccgttttt
     1381 tatcttgagg caaagtcaca cggaattgtc tgggccaacc atggactcct tctgtatctt
     1441 gggcaagcct caaacttgac gcttctacct ctgctcttca agtaacactg tgatgacctg
     1501 cgtggtcctc cagacggggc gggtcaatgc cttctatttt ctttgtgtgt gtgtgtgtgt
     1561 gtgtgtgtgt gtgtgtgtgt gtgtgcacac gcgtacctgt tacccccttt tcccaccgga
     1621 cctagcccca gagagttttc tgcaggcccc agagaactaa gttttactcc ctcagacaca
     1681 agtctgctga gggattgatt aatcactgac tccacacctc tcctcagtgt acctgacctg
     1741 tcaaagctgg tcttcagtac ttgttcctta gtagctagcc atcttgagcc agcccgaggc
     1801 tcatcaattc agctagatcg gcctaccact gagcgttggg catccccttg gctctgcctt
     1861 ctcagcgctg ggtttagggc acacagcact atgccaaact tctaaagtgg attctgggga
     1921 tgagcccagt ttcaagaatg caggtccttt ctcatgctgt ggaacagcac tcttagtgac
     1981 caaaccattc ccttggcttc agaatgaatg tctaagttat tttctacttg tcataggaaa
     2041 taaatatttt tgttacacaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaa
//
