LOCUS       NM_001100529            4993 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus thioredoxin-related transmembrane protein 4
            (Tmx4), mRNA.
ACCESSION   NM_001100529 XM_001081259 XM_215853
VERSION     NM_001100529.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4993)
  AUTHORS   Cheng,L.C., Baboo,S., Lindsay,C., Brusman,L.,
            Martinez-Bartolome,S., Tapia,O., Zhang,X., Yates,J.R. 3rd and
            Gerace,L.
  TITLE     Identification of new transmembrane proteins concentrated at the
            nuclear envelope using organellar proteomics of mesenchymal cells
  JOURNAL   Nucleus 10 (1), 126-143 (2019)
   PUBMED   31142202
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB760647.1, CB582029.1 and BC094304.1.
            
            On or before Oct 24, 2008 this sequence version replaced
            XM_001081259.1, XM_215853.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ102234.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-135               CB760647.1         57-191
            136-637             CB582029.1         101-602
            638-4993            BC094304.1         70-4425
FEATURES             Location/Qualifiers
     source          1..4993
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="3"
                     /map="3q36"
     gene            1..4993
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /note="thioredoxin-related transmembrane protein 4"
                     /db_xref="GeneID:296182"
                     /db_xref="RGD:1305146"
     exon            1..308
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /inference="alignment:Splign:2.1.0"
     CDS             139..1149
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /note="thioredoxin domain containing 13"
                     /codon_start=1
                     /product="thioredoxin-related transmembrane protein 4
                     precursor"
                     /protein_id="NP_001093999.1"
                     /db_xref="GeneID:296182"
                     /db_xref="RGD:1305146"
                     /translation="MTGGFCVPVFLAAWLAAAAAEAEGLEQAALPAEESRVQPMTASN
                     WTLVMEGEWMLKFYAPWCPSCQQTDSEWETFAKNGETLQISVGKVDVIQEPGLSGRFF
                     VTTLPAFFHAKDGIFRRYRGPGIYEDLQNYILEKKWQSVEPLTGWKSPASLTMSGMAG
                     LFSISGKIWHLHNYFTVTLGIPAWCSYVFFVIATLVFGLFMGLILVVISECFYVPLPR
                     ASSERSEQEQRSEEAQGAEQLQDAEEEKDDSNEEENKDSLVDDEEEKEDLGDDDEVEE
                     DEEEDNLAGIMDEEKSDSNEQGVVKEGSVSPKDEEARSADTQDVVEDSLRQRKSQHAK
                     GP"
     exon            309..424
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /inference="alignment:Splign:2.1.0"
     exon            425..470
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /inference="alignment:Splign:2.1.0"
     exon            471..599
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /inference="alignment:Splign:2.1.0"
     exon            600..645
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /inference="alignment:Splign:2.1.0"
     exon            646..747
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /inference="alignment:Splign:2.1.0"
     exon            748..811
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /inference="alignment:Splign:2.1.0"
     exon            812..4955
                     /gene="Tmx4"
                     /gene_synonym="RGD1305146; Txndc13"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggcaggcg tggctgggag cgcgacgctg aggcgagttg gcctctcctc agacctctgt
       61 gaaggcggtt gcttggggtg agaaacccag ccactgctcc cggccctcag agagccgagc
      121 tatctcacag gcgccaccat gacaggcggt ttctgcgtcc cggtattcct ggccgcctgg
      181 ctcgcggcgg cagcggccga ggccgagggc ctggagcagg ccgcgctgcc ggccgaggag
      241 agccgtgtgc agcccatgac cgcctccaac tggacgctgg tgatggaggg cgagtggatg
      301 ctgaaatttt atgctccatg gtgtccatcc tgccagcaga ctgattctga atgggagact
      361 tttgcaaaga atggagaaac acttcagatc agtgtgggaa aggtggatgt cattcaagaa
      421 ccaggtttga gtggccgctt ctttgtcacc actctcccag cattttttca tgcaaaagat
      481 gggatattcc gccgttaccg tggtccagga atctacgaag atttacagaa ttacatatta
      541 gagaagaaat ggcaatcagt tgagcctctc actggctgga agtccccagc ctctctaacg
      601 atgtctggaa tggctggtct ttttagtatc tctggcaaga tttggcatct tcacaactat
      661 ttcacagtga ctcttggaat tcctgcatgg tgttcttatg tttttttcgt cattgccact
      721 ttggtctttg gcctgttcat gggtttgatc ctggtggtga tctcagaatg cttctatgtg
      781 cctcttccaa gagcttcctc tgaacgctct gagcaggagc agaggtctga ggaggctcaa
      841 ggagctgagc agctacagga tgcagaggaa gagaaggatg actcaaatga agaagaaaac
      901 aaagacagtc ttgtggatga tgaggaagag aaagaggacc ttggagatga cgatgaagta
      961 gaagaagatg aagaagaaga caacttggca ggcatcatgg atgaggagaa aagtgacagc
     1021 aatgagcaag gagttgtgaa ggagggcagt gtgtccccga aggatgaaga agctcgttca
     1081 gctgacacac aggacgtggt ggaagactcc ttgaggcagc gcaagagtca gcatgccaag
     1141 ggaccatagg ttacattatg ctacttctaa aaatacaggc caaaaaaaat aagtttgttt
     1201 ccctctggtg tgcagtttaa gccaaatcct tagttgtttg ttttgttttg tttctctgga
     1261 tgagcaatgt tcacttttaa aagatgatct ctggccctgt ggttacgtgg tagtaagctc
     1321 agtgttgtaa gagtcaggtg cagcacttag ccaccatggt gtcaggatct ttgtggggac
     1381 ttgtgcagaa caagtcgatg tgcttgggaa ctaaggagta aatcagaaga cttctctgca
     1441 gttctcatga gcacctttag aaatgaggct gctgcttagt gaagtgagaa caaagccacc
     1501 gcactctgga gcaccttgaa gtagaggaag tctttgccgt caccgttaag catgtccttt
     1561 agtcatgtca gcaacatcag gtcccacagc tccccaacat tatcttgggg ctagaaattg
     1621 tggagacctg gatatagata caacttcaaa atgaagtcat gtaagctctt gtggtctctg
     1681 ttgtcttttg tttcttacct ttaatctcta tgacttttcc tctttgactt gcagactcca
     1741 tttcacagct gctctgtagt gagaagagca ggcagcagtg atctgcatgc gttaccctta
     1801 attgaagtaa agcttgaggt aatcagtaat cacagctgat gatgccaaga ccgccaagtg
     1861 tctcaaagat atgctgtact ctgaaaaagc aaaagagagt agtggattca taggacaggt
     1921 ataaacaaca tcttgcttgg gtccctatag ttacaggatg acttcttcaa gtttcttcag
     1981 ccacattctt tgtttttctg aaccgaaaaa cacctgtcac tacaaggtag ttttctaaag
     2041 ctgacttcat gtctgtgata gtttccatct ccaggaatct ctctggaatc actttaataa
     2101 ccactgaaaa ggcatgtcgg ctttgctttt cttgatgtgc ttttggtgaa aaaattgatg
     2161 aaagtcaata tcaagaggtg aaagatttga tttgtttctg tctctcttga tcctctagag
     2221 aattgtatga ttataaatct ctccctgctc aatctaatat cagtgtcaag gaacccagct
     2281 ttcttaaaaa aatatttcca tctcctctct taccctctca tgtctgcaaa taaatgcata
     2341 aaatagattt tagctgtatg aaagatgact aaagtgaatc ttattaccct tgggttgact
     2401 cagagtaatg agtttaggtt tgtgaaattc aaaatgtttc gacattttaa aaagggatat
     2461 gtagtgtaat tctctgtctg cttagataac cctttgctgc caacaggaga gtcattggta
     2521 gtggaggttc agaattcgcc ctcctatact gcacaagcct gctacaaact ttgcacaaag
     2581 gaagatttta ttgtgacaat ccattcttta tcaatgtttt tatttcatct ttgtaactta
     2641 gttaactatc agttcaaggc taaggctatc acagaactgg agacctactt cccttccatg
     2701 tttctgccct tctgatacat ccttactcaa aagtgccatg gttctgtggt acttcctgct
     2761 atatcttcct actagagcta agctgcacct tctcttttgc cagtgcattt tgtttccttg
     2821 taatcagatg catggagtgt gtaatagtaa atctatgttc agggtatgga aaagggaagg
     2881 cttgtgtcgc tgttctgtga cgtaccctcc tccaaattga catactgggt tctagtgcga
     2941 taattgagca gaggaaaact tgaagactta cagtcagcct tagctttgat aaatgtttta
     3001 aaaccacatt ccagttggac cacaaatact atctaataat ataatgagat aatatatttt
     3061 ctttcttaat aatacttaaa agatattgga ggctgggaga aagggccacg aagaagaggc
     3121 ctaaaattat atttattcgt aggaacaaat ttttcctagc ttttctcttt ttaatatcct
     3181 ggtaaaaatt gggtttctag taaatagtcc aggaagtatt tatttaactt aatttctttt
     3241 gatgtaaagc ctttaggtta attttcaata ctttgttaat ataaaattaa agggaaagac
     3301 caacttacga ttagatcaac atttaatatc actttatttt tgtgtatata ataaatttaa
     3361 tccagaagtt aagtgcatga aaacatgatt ttataaaaca aaactaacca tgcttcccct
     3421 ccattgccat acctgctatt taattgtaga ttgctatttt ctgtatgtta aaattgggtg
     3481 aatgagatag caattgtgga atgaggatat atagtgcttt atggacaggt agttagagaa
     3541 aggtgccttg ttcttcattg gaatatctga aaattccacc tctttttaat ttttcttagc
     3601 acttcacccc ttaaccatgc tgaaccacag cagcttgctt agaatctcat ggaagcaatg
     3661 cacaggcaaa ttcacgtttt tgttgttttg attgttttga ttttgaaagc taatcgtgga
     3721 acacggaaga gatggctcat tcagtgcaca ggccatttcg ctgggtgctg tggcagtcac
     3781 tgcagtctca tcctatacat aggctctgta cctgttacta tagtaactag tgcagtggaa
     3841 ggcaaacacg cttgacaaga tcgtctctgg gtagctgaaa agctacactc tcacatttta
     3901 gggccacccc atgactgata attaagatac tgctgtgtag tttgagtatg tgtaaacttg
     3961 aataagagca ccttgtaaca tcttttgacg aggagattaa aatgctagtt aacagaatat
     4021 ctaccatgtt gctttttgca tgatgggaaa caatggagtt caaagggaag ttttaaagga
     4081 atgaaaaggg tgaaagatat ttcagcatta aaatcctaag catgaagtga aaggagagat
     4141 tggtacttct gctggtgtat acaggttttc tgtgttcttc tcttagtgtt ccgctgttat
     4201 tcctgccagt attgtacatg cgtgattgac ttgcctgtca aatctatcaa gtattggaaa
     4261 gtatttgtgt aaatctttgt gccaacaaga attctcccag tgttgtgtat ctttacctca
     4321 taccattcat tgatatggtt cttgtgagat tgtagcttgt ctgacagaag ccaaggtgga
     4381 atccgatgaa acctgccggg caggaggttc aactgagaaa cctaagacag cttcagccta
     4441 gcatgtggac ctcagcggca tagtctctaa agttttgtgt aaactgtgat gttcacctgt
     4501 ggctttgacc catttctgat gtggtttaat tttatttctt tctggacagc tttgtagaaa
     4561 tggaattttt atactaaaga cactgttcac ttgtaagtca atacattata aaatggtgta
     4621 tttatttttt gtaatagtgt ggattgttta gcccagtgta tttattttcc tttacctgtg
     4681 tattctgtgc tctcaaatag atgtgtagca attgaaatga gaactcagtg catcatttca
     4741 agcactacat tgcctgcatt gcaaattctc tgagcacagg attgtacaga accctgagcc
     4801 tgtgtactgc catttgattg tcagttccat ttgtgtcaaa acctaaaggt ggtgatgacc
     4861 aagtgaaaca gagtgctgta ctgctttttc atatgaatat tttcacataa aagcatttgt
     4921 gaaagcagtt gaaaatatta ctttgtttaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     4981 aaaaaaaaaa aaa
//
