LOCUS       NM_001024800            2807 bp    mRNA    linear   ROD 01-APR-2024
DEFINITION  Rattus norvegicus thioredoxin-related transmembrane protein 1
            (Tmx1), mRNA.
ACCESSION   NM_001024800 XM_343076
VERSION     NM_001024800.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2807)
  AUTHORS   Pasetto,M., Barison,E., Castagna,M., Della Cristina,P., Anselmi,C.
            and Colombatti,M.
  TITLE     Reductive activation of type 2 ribosome-inactivating proteins is
            promoted by transmembrane thioredoxin-related protein
  JOURNAL   J Biol Chem 287 (10), 7367-7373 (2012)
   PUBMED   22228764
REFERENCE   2  (bases 1 to 2807)
  AUTHORS   Matsuo,Y., Akiyama,N., Nakamura,H., Yodoi,J., Noda,M. and
            Kizaka-Kondoh,S.
  TITLE     Identification of a novel thioredoxin-related transmembrane protein
  JOURNAL   J Biol Chem 276 (13), 10032-10038 (2001)
   PUBMED   11152479
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000006.1.
            
            On Apr 23, 2021 this sequence version replaced NM_001024800.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC094308.1, SRR22582416.616296.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-220               JAXUCZ010000006.1  94696699-94696918
            221-336             JAXUCZ010000006.1  94699564-94699679
            337-382             JAXUCZ010000006.1  94700122-94700167
            383-511             JAXUCZ010000006.1  94702289-94702417
            512-557             JAXUCZ010000006.1  94703762-94703807
            558-659             JAXUCZ010000006.1  94703893-94703994
            660-726             JAXUCZ010000006.1  94704098-94704164
            727-2807            JAXUCZ010000006.1  94705671-94707751
FEATURES             Location/Qualifiers
     source          1..2807
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="6"
                     /map="6q24"
     gene            1..2807
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /note="thioredoxin-related transmembrane protein 1"
                     /db_xref="GeneID:362751"
                     /db_xref="RGD:1308455"
     exon            1..220
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /inference="alignment:Splign:2.1.0"
     CDS             69..905
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /EC_number="5.3.4.1"
                     /note="thioredoxin domain containing 1"
                     /codon_start=1
                     /product="thioredoxin-related transmembrane protein 1
                     precursor"
                     /protein_id="NP_001019971.1"
                     /db_xref="GeneID:362751"
                     /db_xref="RGD:1308455"
                     /translation="MAHLGRLLVPLAALVLLLWAVPGAHGRRSNVRVLTDENWTSLLE
                     GEWMIEFYAPWCPACQNLQPEWESFAEWGEDLEVKVAKVDVTEQTGLSGRFIITALPS
                     IYHCKDGEFRRYLGPRTKKDFINFISEKEWKNVEPVSSWFGPSSVLMTTMSALFQLSV
                     YIRTSHSYFVHDLGIPAWGSYLVFAFATVLSGLLLGLCMIFVADCLCPSKRRRPQQQP
                     TKKPSPEFSQPLKKVEEEQEADEEDVSEEETENREGESKDTPQSGLRQRCVGPSSATD
                     KS"
     exon            221..336
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /inference="alignment:Splign:2.1.0"
     exon            337..382
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /inference="alignment:Splign:2.1.0"
     exon            383..511
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /inference="alignment:Splign:2.1.0"
     exon            512..557
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /inference="alignment:Splign:2.1.0"
     exon            558..659
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /inference="alignment:Splign:2.1.0"
     exon            660..726
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /inference="alignment:Splign:2.1.0"
     exon            727..2807
                     /gene="Tmx1"
                     /gene_synonym="Txndc1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cagagcggaa gtggagctgc ggcggggcgg tggggcggga gcgctctgag actgggcaag
       61 tggctgacat ggcgcacttg gggcgtctcc tggttcccct ggcagccctg gtcctgttgc
      121 tctgggcggt ccctggggct cacggacggc ggagcaacgt gcgcgtcctc accgatgaga
      181 actggacctc attgctggaa ggagagtgga tgatagaatt ttatgctccc tggtgccctg
      241 cgtgtcagaa tcttcagcca gaatgggaaa gctttgctga gtggggagaa gatctggagg
      301 ttaaagttgc aaaagtggac gtcacagagc agacagggct gagtggacgg tttatcataa
      361 ctgctcttcc ttctatttac cattgtaaag atggtgaatt taggcgctat ctgggcccaa
      421 gaactaagaa agacttcata aacttcataa gtgagaaaga atggaagaac gttgaacctg
      481 tatcatcatg gtttggtcca agctctgttc tgatgaccac tatgtcagca ctttttcagc
      541 tctctgtgta catcaggact agccacagct attttgttca tgaccttgga atcccggcat
      601 ggggctcata cttggttttt gctttcgcaa cagtgctctc aggactcctg ctgggactct
      661 gtatgatatt tgtagcagat tgcctttgcc cttcaaagag gcgcagacca cagcaacagc
      721 ctacaaaaaa accatcacca gaattttctc aacctctgaa gaaagtggag gaagaacaag
      781 aggctgatga agaagacgtt tcggaagagg agacagaaaa tagagaggga gagagcaaag
      841 acactcctca gagtggccta agacagcgct gcgtgggccc gtcatcggcc acagacaaat
      901 cctaagtttt acacatatct taatactatg attttggcag aactgaagat tggtgatgat
      961 ctctgttgca aactgaactt gacttgctgt atatacagtt tataggttgt cgctaggttg
     1021 gacagttttc attcaggaaa taaaagcagt tagacataac agtttgaaag atgatttaag
     1081 aatattatga tggtttaaag ttgtttaatt tcagaagagc ctggtgccaa gcactgagac
     1141 ttgtgtttat atttaataat ctattttgtg tgcgactcaa aactgccttt cccaagattt
     1201 gcattactgg ggtatttaag aaaatcaccg tagagagaag gatttctcat ttcacagcat
     1261 tttctcagtt tcactgtgtg aaaaaggatc atatttccca taagtgggag cattgcccat
     1321 gtttccagac gtgtacttca tgatagcgct acgctttggt agagtccata gcttcctcac
     1381 agattttgga ttatacagct aacaaaacta ccttacctta tagctttcat ttccacacat
     1441 tacatttagg atatgctgct gacttaagaa gtttttataa gtctatggca ttgtgttaat
     1501 tcttaaggtc gatgcctgtt ttggtctcgt gttcactgta tgatttttat ttgccatgtg
     1561 tttttaaagt tggaaaaaat taacaatatc actgtttgtt tactgtgggt aaacagaact
     1621 tttctatcct tttaagttga agtttacgga gagaaccatc aaactgaact gtttacttga
     1681 aaatgtacaa atttggctat acattccaga ttttaaatta ttattaaatg gtcttgacgt
     1741 tttcttttct ctttttaatg cgaagatgaa attttctgat ttttaaaatt tgatgtggaa
     1801 aagctttggt attttatatt ttggaaattc agagcttaat ttgatgtaaa atgaagtctg
     1861 cattctactc aagaaatatc tactactatg tgattttact gtatctctgt cctctacagg
     1921 ttcttgatga attttatagt caggatattg ctttgtgttt gaaaatcgta acactgttat
     1981 gttttaaaga caaatttcat attgtattgt tcttgactgc tagtactgtg catctcacaa
     2041 gtggagatca ggtcagcaag atgactacat ggatttcatc ttacagaaag ggaagggtgt
     2101 cgtcggggat tgtctgatgt ctggaagggg aaaacagact aaattcttca tgagtcatcc
     2161 agcctttgtg gaatagatgg tgtctgtgat gctccctccc cttacgttct ctgtgtgaat
     2221 tccttagact cgcagaactg tgatgtgtga cagcttcctt taggcctctc ctttacagta
     2281 ttaaatgttc tgctgtcagt tatgtagttt gtggtggctt agaaaaacat tctaagcaca
     2341 aaataaatgt ttctaagcac ttcagtgatg gtgaagagaa gtatgatttc tgttggtttc
     2401 ttttcagagt ctgtaaccca ggctggcctc cagcactgta tagccaagag tgatagaacc
     2461 aatggtcctc cacccctatt agccggaggg taggactgtg ggcgtgcacc atccctgagt
     2521 gccctcctgc atgccgggca agcatgagct cagtctctag cccagcagtg atagtaagca
     2581 ggttccgttc ttaaccactt acccctcagc agtgctctgg gacatggggt agggccacca
     2641 cctgcgtgct tcctgtggtc ccagatgact agtcttgtca atcatttcag gagaacaatg
     2701 ctctgtagtc aacattttgt tcttagtgtt tctgttgttc tctaacattg gtaagttttt
     2761 aactagaaaa tgctttatta cagaaaaata aaagtatact gaattaa
//
