LOCUS       XM_039078703            6553 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus transmembrane O-mannosyltransferase
            targeting cadherins 2 (Tmtc2), transcript variant X1, mRNA.
ACCESSION   XM_039078703
VERSION     XM_039078703.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051342.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039078703.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6553
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..6553
                     /gene="Tmtc2"
                     /gene_synonym="RGD1309848"
                     /note="transmembrane O-mannosyltransferase targeting
                     cadherins 2; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 5 ESTs, 1 long SRA read, 1
                     Protein, and 100% coverage of the annotated genomic
                     feature by RNAseq alignments, including 45 samples with
                     support for all annotated introns"
                     /db_xref="GeneID:299762"
                     /db_xref="RGD:1309848"
     CDS             35..2491
                     /gene="Tmtc2"
                     /gene_synonym="RGD1309848"
                     /codon_start=1
                     /product="protein O-mannosyl-transferase TMTC2 isoform X1"
                     /protein_id="XP_038934631.1"
                     /db_xref="GeneID:299762"
                     /db_xref="RGD:1309848"
                     /translation="MIAELVSSALGLALYLNTLSADFCYDDSRAIKTNQDLLPETPWT
                     HIFYNDFWGTLLTHSGSHKSYRPLCTLSFRLNHAIGGLNPWSYHLVNVLLHAAVTGLF
                     TRFSKALLGDGYWTFMAGLMFASHPIHTEAVAGIVGRADVGASLFFLLSLLCYTKHCS
                     TRGYSARTWGWFLGTGLCAGCSMLWKEQGVTVLAVSAVYDVFVFHRLKMRQILPTIYK
                     RKNLSLFLSISLLTFWGTSLLGARLYWMGNKPPSFSNSDNPAADSDSLLARTLTFFYL
                     PTKNLWLLLCPDTLSFDWSMDAVPLLKTVCDWRNLHTVAFYSGLLLLAYCGLKSPSLE
                     GECNGKAVTNGKQNANGHSCYSDVEYRNSEIKPSFASKVENGIKSCVSQRPQLPSTEN
                     IVILSLSLLIIPFIPATNLFFYVGFVIAERVLYIPSMGFCLLITVGARALYVKVQKRF
                     LKSLVFYATATLIVFYGLKTAIRNGDWQNEEMLYRSGIKVNPAKAWGNLGNVLKSQSK
                     ISEAEIAYRNALYYRSNMADMLYNLGLLLQENSRFAEALHYYKLAVGSRPTLASAYLN
                     TGIILMNQGKTEEARRTFLKCSEIPDENLKDPHAHKSSVTSCLYNLGKLYHEQGRYEE
                     ALSVYREAIQKMPRQFAPQSLYNMMGEAYMRLSKLPEAEHWYMESLRSKTDHIPAHLT
                     YGKLLALTGRKSEAEKFFLKAIELDPTKGNCYMHYGQFLLEESRLTEAAEMAKKAAEL
                     DSTEFDVVFNAAHMLRQASLNEAAEKYYDLAARLRPNERTRKGLGTNLPALSTPFPLS
                     SRIQFSRTSCSATAVLNRFP"
ORIGIN      
        1 ctgggagcca agccggaggg aaggcggtgg agagatgatt gcagagttgg tgagcagcgc
       61 tctggggctc gccttgtatc tcaacaccct gagtgcggat ttctgctacg atgacagccg
      121 tgctatcaag actaatcagg acctgctgcc agaaaccccc tggacccaca ttttctataa
      181 tgatttctgg gggactcttc taacccacag tggtagccac aaatcctacc ggccgctctg
      241 cactctttct tttcgactga atcatgccat cggagggctg aatccctgga gttatcacct
      301 tgtcaatgtc ctgttgcacg cggccgtcac cggcctcttc acacgcttct ccaaggccct
      361 gcttggggac ggatactgga ctttcatggc gggcttgatg tttgcctcgc accccattca
      421 cacggaggca gtggcgggca tcgtgggccg ggcagacgtg ggcgccagtc tctttttcct
      481 cctgtccttg ctctgctaca ccaagcactg ttctacaaga ggctactcag ccagaacttg
      541 gggctggttc ctggggacag gactgtgcgc tggatgcagc atgctgtgga aggagcaagg
      601 agtgaccgtc ctcgcagttt cagccgttta tgacgtcttt gtcttccaca ggctgaagat
      661 gaggcagatt cttcctacca tttacaaaag gaagaacttg tctctctttc tcagcattag
      721 cttgttaaca ttctggggga ccagcctttt gggtgcccgg ttatactgga tgggcaataa
      781 accaccaagc ttttccaact ccgacaaccc cgctgctgac tcggacagcc ttttggctcg
      841 cacgctcact ttcttctatt tacctaccaa gaacctctgg ctattgctct gcccggacac
      901 cctgagcttt gattggtcca tggacgccgt gcctcttctc aaaacagttt gtgattggag
      961 aaatctacac actgtggcct tctattctgg acttctcctg ctcgcctact gtggtttgaa
     1021 gagcccaagt ttagaaggag agtgcaacgg gaaagctgtg acaaacggca agcagaacgc
     1081 caatggccat agttgctact cagacgtgga gtaccggaac tcagaaatta agcccagctt
     1141 tgcatccaaa gtagagaatg gaattaaaag ttgcgtatca cagagacctc agctcccttc
     1201 cactgagaac attgtcatcc tgtctttatc tttgttgata atacctttta ttcctgccac
     1261 gaacctgttt ttctatgtcg gctttgtaat cgcagagcga gtcttatata ttcccagtat
     1321 gggcttctgc cttctgatca cagtgggcgc cagagccctt tatgtcaaag tacaaaagag
     1381 gtttctcaag agcctggttt tttatgctac agcaacgtta attgtcttct acggactcaa
     1441 gactgcgatc aggaacggag actggcagaa tgaggagatg ctgtatagat cagggatcaa
     1501 agtgaacccc gccaaagcat ggggtaacct tggaaatgtt ctgaagagtc agagtaaaat
     1561 ctctgaagct gaaatcgcct atagaaatgc tctgtactac cgcagcaaca tggctgacat
     1621 gctgtataat ttagggttgc tgctccaaga gaacagcagg tttgcagaag ctctccatta
     1681 ttacaaactg gctgtcggca gcaggcctac cctggcttct gcctatttaa acaccggcat
     1741 cattctcatg aaccaaggga agacagaaga agcccgacgt acattcctca agtgttctga
     1801 gattccagat gagaatctga aggatcctca tgcacataag agttctgtta ccagctgcct
     1861 gtacaacctc gggaaactct atcatgagca aggacgctat gaggaagccc tgagtgttta
     1921 tagggaagca attcagaaga tgccaaggca gtttgcccct cagagcttat acaacatgat
     1981 gggcgaagcc tacatgagac tgagtaagct tcctgaagct gagcattggt acatggaatc
     2041 attgagatcc aagacggacc acatccctgc tcatcttacc tatgggaagc tgctggcgct
     2101 aacaggtcgt aagagtgagg ctgaaaagtt cttcttgaag gctattgagc tggatcctac
     2161 caaaggaaac tgttacatgc actatggtca gtttctcctg gaggaatctc gcctcacaga
     2221 agcagccgag atggcaaaaa aagcagctga gctggacagc acagagttcg atgtcgtctt
     2281 caatgctgcc cacatgctca gacaagctag cctcaatgaa gctgcggaga agtattacga
     2341 tcttgcagca agactgagac ctaatgagag aacaagaaaa ggtcttggga ccaacctgcc
     2401 tgcattgtct actccgttcc ctttatcttc acgaattcag ttttccagga cgtcctgttc
     2461 tgcaacagct gtcctgaacc gcttcccata gttagcagac gactggggaa ctgacaagct
     2521 gtttgcaaca gagaaaacca tcctaatggc aagtgcagtg acagctaaag tttattgtac
     2581 actcacctgt cactcacttt gctaggtact ttgcaagaat ttgtttattg caacccctca
     2641 gctgctttcg tggcccagaa ggtgcccaag ttaatgcctc gcctgacaac acagctttat
     2701 agagtcactt tgtcatttaa aagaaaaaag gaaagcttaa caaagtttaa aggggtgtgg
     2761 ggaagcaaag cgccacgagg ccatacacat tgtctatgtg gcgagccagc atactatcag
     2821 caaaaatcag tttctttgct cattttgtgt gtctagtgag taccaggtcc tattgtaggc
     2881 actgtaggag agagagattt cctgtagaaa cttaaaactg ggctgaagcg agaaggctac
     2941 ataatatctc agacagtgct gcgtgtttgc agaaaaaatg aagcagtacg gaagttagga
     3001 atccaaccga aaaagaaacc cctaaatttt ctagtttgat acctttgtgc agtttttaaa
     3061 gactttgaag aagtgtttca cctacagtca cattgaaggc aggcaacagg gaggggggat
     3121 ctgctttctt ttcatggagg ttgattgaca taatatgttg taaacatatg taaactacat
     3181 gataattaag atgagctttt cttcttggca aatcaggtcc tctgaatgtc acatttaata
     3241 ttgctgtgtg attggttaaa tgatggtctt tatcacagaa taacatcata gggaaaaaca
     3301 aatgtctgag ctgtctggcc tctggaaaaa agaaagatac ttagagtcag agtgcaagcc
     3361 tgacttacca agttgcgttt taaaaaaaaa tgactgtcca aatcataaaa tcaatattta
     3421 atctccaatg caacaccctt ttcccgagag accctaaaat atttcaccat caatttgctt
     3481 ttgaaaatgc atttattcaa acgatccttt ccataactgg caggattgtt tttttattga
     3541 ctttgttata aagtttccat ttaacaaaaa gtaaatggtg ttttaattga cagatcaaca
     3601 gatgtgcatt gttcccaatt aattttcaat ttgcttgggt tcttagttga tactctagtg
     3661 tatataaagt gacacagaga ccagaaggat gggattgcaa accatgtcac ttgtattttt
     3721 ttgtctgaaa tggagaactc tttgagcaac agttgtagtt tattgggaat cctgcatttg
     3781 aggtaaacag aagcacctac ccaacatgca tcttgctatt cattaattcc ctttgttcat
     3841 aaaagcatct ttttgttctt tgctgcagtt aatttaacaa atgacattat tgattacttg
     3901 tttgtaagag agaggagacc taacagatat caattctcct ggcctgttta aatagagcca
     3961 tttctcattt tgttttgttt tgttttgttt tctcatctac actagtcagc caaacttact
     4021 cctgtcataa actttctctt ctttttgggt aaatgaatac catttccatt gtggtcatca
     4081 gggtgctgtt tgtggataac taaaggtcta acagtgctca tgtggggcca tactgtataa
     4141 taatgtaaag agggtgactt gtgtgacaca tcttattacc aatatttaag aggttttgat
     4201 gggaatggag agatggttca ttggctaagg atgggttcgc caggcttccc agaagccact
     4261 tcagcaatcc acctctaact ccactgcctg ggatggcctc cctggactcc agggccactg
     4321 agcttctgtg cttattatat acacaacctc ctctctcact gatatacaca tgtatgcata
     4381 atttacaata aaatctcttt ttaaaggatc tttatttctg agatatactt atttctttgt
     4441 aaagtactga ttccattcat ttttacctac cctgcaattt ctctctccca aagcatattg
     4501 ttctacagaa tttatggtga aatagattga ccttttgtag tgtagctcca gtgataaaat
     4561 gttgaaataa tgaaaccaat ctagatagtt aggagcattg tagagtttta gaattagctt
     4621 tgtctgctgc tacagcacct gatatgtggc ctcactggag ggcacaactg gagggtcttg
     4681 atcgttcgca gcacacatca tcggtctgtc tgctatagcg tgccagattc caccttctta
     4741 gcagataatg tgtggaaatt gttctaaaag tagatctctt gttccactaa tttttttttt
     4801 ttgcaatacg aaaaaggatc ttagcaacat agcgtttgtt agtttccctt gttataagtt
     4861 gagctttgtg cagaattaac tctgtgacga tccttttctg tctacctccc ccatccactt
     4921 aagcacatca aaaactgctg actcctgaga gctagggaac atttaaagga aactactttg
     4981 ttctttgatt gggaatgaag ccaaagtctg cattatctta aggataaaag atttaatgtg
     5041 aggaataggg aatttgcatg gtacagagtc acctaccttt acttgacttc ttatattttt
     5101 ggttgtgagc ctagccttta acggctgagc catctctcca ccccctttac ttgacttctt
     5161 attcgctctt gagtccaggc ggcaaaatta ctggtgcctg ggttttcagg gcagatttgt
     5221 cgatggcgta tagtcattgc agccatttct aactcaagtg tcaacattat atacgactct
     5281 gcctgatgga atagagtttc acagttatga aaatttacct ctgaccttga gaactataca
     5341 acataatgta aaaaaggggg acaagggcag gaatgtgcct ctcagtcctc agatatcgga
     5401 acagtaaata atgctatcaa ataagggctt tggggaggat gtaaattagg tgcaaaataa
     5461 gtggaaagga gaaatttact ttcatctggg ttggtcttaa aaggctttga gttggagtag
     5521 gaaagcttaa agatccttgg aatgagagaa tcgtataggg gatttcagca aggaggagga
     5581 agcaaattcg agcagtgggg tcgcatagag aggcaaggaa aacagcagga aaaaatggaa
     5641 ttgataattc atctaaaaac aggtgaaatt cattgggtat cacccttaaa gatcagaagc
     5701 ctctactctc tgattttgac caccagtata acagtagaaa gtagtaattg aggatgacat
     5761 aaaaatgtgt attatgttca gagaagtagg actgaaggcc cagccatggt agaaacaaat
     5821 aaagatcatt gtaagtgtaa ggcaatcaag agtaagggtg gaaacagagt gagatagaaa
     5881 atatatatat atatgtatat atgtatatat atatacacat atacatatat ataggaaaat
     5941 tgtgagtagg aaaatttgac ttcaggtaac ttagaaacaa agaaatatca taagacaaaa
     6001 taagattatc agagttgtat gtttatttca agaacagagt cttaggtttg aacttaacat
     6061 attctgaatg agtataaggg tgtgtgggtg tgtgtactat tgtctgtgtt gtgtgtacac
     6121 acataggtgt gtatatgtgg atgagaggct ctggaggcca gcagttgatt ttgtgtgtct
     6181 gcctttattg atcttcactg tagttcggac acacattctc ccattgtgcc tgaaactcat
     6241 cagttcggtt ggtctggcta gcctggctga ccagcaagcc caggaatcct aatgtctcca
     6301 gctcactagc tctgtcactg tagatgagca cagtcattct taaagtttta catgaatgtt
     6361 aaggaacaaa gccaagtctt cctgactgtt tagtaaacat tacactggct gagttgcctc
     6421 caaagcccta ttctgaattt ctttttcttt tttaattaat cactttattc atttacgttt
     6481 taaacaatat tcttctcggt ttcccctcca caacccccca atcccatccc cttcttcccc
     6541 ctcccatttg cct
//
