LOCUS       XM_039108899            8434 bp    mRNA    linear   ROD 11-JUN-2023
DEFINITION  PREDICTED: Rattus norvegicus transmembrane O-mannosyltransferase
            targeting cadherins 1 (Tmtc1), transcript variant X1, mRNA.
ACCESSION   XM_039108899
VERSION     XM_039108899.1
DBLINK      BioProject: PRJNA677964
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_051339.1) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Feb 22, 2024 this sequence was replaced by
            XM_039108899.2.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Updated annotation
            Annotation Name             :: GCF_015227675.2-RS_2023_06
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.1
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 06/06/2023
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8434
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN/NHsdMcwi"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney"
                     /geo_loc_name="USA: Wisconsin, Milwaukee, Medical College
                     of Wisconsin"
                     /collection_date="2019-03-08"
                     /collected_by="Rebecca Schilling"
     gene            1..8434
                     /gene="Tmtc1"
                     /note="transmembrane O-mannosyltransferase targeting
                     cadherins 1; Derived by automated computational analysis
                     using gene prediction method: Gnomon. Supporting evidence
                     includes similarity to: 43 ESTs, 3 Proteins, and 99%
                     coverage of the annotated genomic feature by RNAseq
                     alignments, including 134 samples with support for all
                     annotated introns"
                     /db_xref="GeneID:362465"
                     /db_xref="RGD:1564868"
     CDS             153..2981
                     /gene="Tmtc1"
                     /codon_start=1
                     /product="protein O-mannosyl-transferase TMTC1 isoform X1"
                     /protein_id="XP_038964827.1"
                     /db_xref="GeneID:362465"
                     /db_xref="RGD:1564868"
                     /translation="MLVTRGDRGGGERAPSRRPRWGLVPAGAAALLTGASCLCYGRSL
                     RGEFVHDDVWAIVNNPDVRPGAPLRWAVFANDFWGKGLADSTSHKSYRPLCVLSFRLN
                     IFLTGMNPFYFHAVNVILHCLVTLVLMYTCDKTVFKNRGLAFVTALLFAVHPVHTEAV
                     AGIVGRADVLACLLFLLAFLSYHRSLDQDCAGQCFPPTASPFFLLLSLFLGTCAMLVK
                     ETGVTVFGVCLVYDLFSPSHKQDKLSNGAICQHSPRQPGSPQPSSQQAHPHRESRKQR
                     FPHRDTWGGCHSPLPPEPKSSGFPVSPRALWSLMRCLTGNSNRSFLLTLRPFLKRAIL
                     VISYVTVILYFRLWIMGGTMPLFSEQDNPASFSPYILTRFLTYSYLLAFNVWLLLAPI
                     TLCYDWQVGSIPLVETIWDVRNLATILLAVVMALLSLHCVAAFKRLEHKEVLAGLLFL
                     VFPFIPASNLFFRVGFVVAERVLYMPSMGYCILFVHGLSKLCAGLSRCGATSLMASTV
                     LLLLLFSWKTVKQNEIWLSRESLFRSGVQTLPHNAKVHYNYANFLKDQGRNKEAIYHY
                     KTALKLYPRHASALNNLGTLTKDMAEAKMYYQRALQLHPQHNRALFNLGNLLKSQEKT
                     EEAIVLLKESIKYGPDFADAYSSLASLLAEQERFKEAEDVYQAGIKNCPDSSDLHNNY
                     AVFLVDSGFPEKAVAHYQQAIQLSPSHHVAVVNLGRLHRSLGENSMAEEWYRRALQVA
                     RTAEVLSPLGALYYNTGRHKEALEVYREAVSLQPSQRDLRLALAQVLAVMGQTKEAEK
                     ITSHIVSEEPRCLECYRLLSAIYSKQEHHEKALEAIEKALQLKPKDPKVISELFFTKG
                     NQLREQNLLDKAFESYEAAVTLDPDQAQAWMNMGGIRHIQGSYVPARVYYERALRLVP
                     ESKLLKENLAKLDRLERRLQEVRERDQT"
ORIGIN      
        1 ttatttgcag ctgggccacc gcggcggcgg agcaccgggc gcccgggcgg ggacattagg
       61 cgcgcgatgc ccgagccaag caggccgccg cgcgcccggg tcccggccgg agaggatgcg
      121 cgccgcgcgg gagcggccgt gcgggcggtg cgatgctggt gacccgcggg gaccgcggcg
      181 gcggggagcg cgcgccctcg cggcgcccgc gctgggggct ggttccagcc ggggccgcgg
      241 cgctgctaac tggggccagc tgcctttgct acggccgctc gctgcggggc gagtttgtgc
      301 acgacgatgt gtgggcgatc gtgaacaacc ccgacgtgcg acccggggct ccgctgcgct
      361 gggctgtctt cgctaacgac ttctggggca agggcctggc ggacagcacc agccacaagt
      421 cctatcggcc gctatgcgtg ctgtccttca ggctaaacat atttctgact ggcatgaacc
      481 ctttctactt tcacgcggtc aacgtcattc tacactgcct ggtgaccctc gtgctgatgt
      541 atacctgtga taaaacagtc ttcaagaatc gaggactggc attcgtcaca gctctgctct
      601 ttgcagtgca cccggtccac accgaggcgg tggctggcat cgtgggcagg gctgatgtac
      661 tagcatgcct cctgttcctg ctggcctttc tctcctacca caggagtctg gatcaggact
      721 gtgcaggaca gtgcttcccc ccgacggctt ctcccttctt cctgttgctc agtttgtttc
      781 tggggacctg tgccatgctg gtgaaggaga caggcgtcac cgtgtttgga gtgtgcttgg
      841 tttatgatct cttctccccc tcccacaagc aggacaagtt gagcaatggg gccatatgtc
      901 agcacagccc gaggcagcca gggagccccc agccctcctc tcagcaagcc cacccccacc
      961 gtgagagcag aaagcagcgc ttcccacaca gagacacctg gggaggctgc cattcgccat
     1021 tgccaccaga gcccaagagc agtggattcc ctgtgtcccc gagagcactg tggtcactga
     1081 tgaggtgtct aacaggaaac agcaacagaa gcttcctgct taccctgaga ccgtttttaa
     1141 agcgggccat tctggttatc agttatgtga ctgtcatttt gtatttccgc ctgtggataa
     1201 tgggaggaac tatgcccctc ttctcagagc aggacaaccc agcttcattc tcgccgtaca
     1261 tccttaccag gttccttacc tattcctacc tcctggcctt caatgtatgg cttctgctgg
     1321 cacccatcac cctgtgctat gactggcaag tgggcagtat ccctctggtg gagaccatat
     1381 gggatgtgag aaaccttgct accatccttc tggcagtggt gatggcctta ctgagcctgc
     1441 actgtgtggc agccttcaag aggctggagc acaaggaagt gttggccggc ttgctgttcc
     1501 tcgtgttccc gttcattcca gccagcaacc tcttcttcag ggtgggcttt gtggtggccg
     1561 agagagtcct gtacatgcct agtatgggct actgcattct ctttgtgcat ggactgagta
     1621 agctttgtgc tgggctgagc cgatgcgggg ccacttccct gatggcatcc actgtgctgc
     1681 tgctgctgct tttttcctgg aaaactgtga agcagaatga aatttggctg tcgagagagt
     1741 ccttattcag gtctggagtt cagactctac cccacaatgc caaggttcat tacaactacg
     1801 ccaatttcct caaagaccaa ggtcggaaca aggaagcgat ctaccactac aaaactgccc
     1861 tcaagctgta cccgcgccat gcaagtgcac tgaacaacct tgggaccctg acgaaggaca
     1921 tggcagaagc taagatgtac taccaaaggg cactgcagct ccacccacag cacaaccgcg
     1981 cacttttcaa tctggggaat ctcctcaagt cccaggagaa aacggaagaa gccattgtgc
     2041 ttctgaagga atccattaag tatggtccag attttgccga tgcctattca agcttggctt
     2101 ctctactggc tgagcaggaa agatttaagg aagctgagga cgtttaccag gctgggataa
     2161 agaactgtcc ggacagctca gacttacaca acaactacgc ggttttctta gtagactctg
     2221 gctttcccga gaaggccgtg gctcactacc agcaggccat ccagctcagc ccaagccatc
     2281 atgtggctgt ggtgaacctg ggccgactcc acaggtccct gggagagaac agcatggctg
     2341 aagagtggta cagacgtgcc ctgcaggtgg cccgcacggc tgaggtgctg tcacctctgg
     2401 gagcactcta ctacaacact ggccgacaca aggaggcact ggaagtgtac cgggaagctg
     2461 tctcactcca gccttcccag agggatctcc gcctggctct ggcacaggtt ttagcagtga
     2521 tgggtcagac caaagaagcc gaaaagataa ccagccacat agtatccgag gagcccaggt
     2581 gcctggaatg ctaccgtctc ctgtcagcaa tctacagcaa gcaggaacac catgagaagg
     2641 cactcgaggc catagagaag gctcttcaac tgaagcccaa ggacccaaaa gtcatatctg
     2701 aacttttctt tacaaaagga aaccagctaa gagaacagaa ccttctggac aaagcctttg
     2761 agagctatga agctgcggtg accctggacc ccgaccaggc ccaggcgtgg atgaacatgg
     2821 gcggcatccg gcacatccag ggaagctatg tgcctgcaag ggtctattat gagagagccc
     2881 tgaggctggt accagagagc aagctgctga aggagaatct ggccaagctg gatcgcctgg
     2941 agaggaggtt acaagaagtc agagagcggg atcaaacata gatcaaaaaa ggacagtcac
     3001 gtgggactca gcaggctgga agaagacaga cttggggagg ccttgcttac cctcagcagg
     3061 ctctcctgat ggcacagtgg gagacgatca ctgatgactg tgctgaaaga gttgtttcca
     3121 tgaagagaaa cagcagaggg gagcagactg tctgcaggga agggggataa gcaagtgcat
     3181 gcttggccgg ctcctgtgtg actcccagtc cccaggatat taagcagtgc tttggcagca
     3241 gatagtgacc tccattctta ctatagccca gaaatacaga gacccgaagt cctgtaaaca
     3301 cagcagttgt tcctaagaaa gcatgtattc tctgaagtca gcccttgtga aatctagagc
     3361 aagttcagtt aattctcaag aatctagaat tggtggtgaa gagagcattg gtagagcctg
     3421 tggagtgcag gggagcagag cacttgatag ctgggcttgg gctaatatcc cccaagggta
     3481 tcattaagca cctttggaga agtacattaa attcttctct ggtatatggg gttttttttt
     3541 tttttttggt tttttttttc tttttctttt tctttctttc tttttttttt ttagtgccta
     3601 aaacaccaag atggaatctt ctagaattgt atgtggctat gcttatctct atagaaaatc
     3661 agagctcccc atccttgatt ctctatggaa atgttttaaa tgtttgaact gtattccaag
     3721 agttgtttct ccacgctgaa ccttctgagt gcattaacca tgaggttggg accctgaaat
     3781 gtattgctca ggtggggagc tgccggctgc actctgcgta gaagtgttaa agggtcgggc
     3841 cagagaagga ctctgcttta ttctcgtaag gtcaagattg tgaggtttat tgtttctgaa
     3901 tgatatattt gagcactgag gaatctttac attatattac agaattcctc acagactcta
     3961 gagggaagag tattctgtca ctgacttttg aggtttagtg aggattctgt atttaaaacg
     4021 caagtgagtt tggagacgtc atagagaata ctctaaaact ctaggatgaa gtctaaattc
     4081 ataatttttt aaaaaaatat atttatattt gaaaataagg aaggcaaagt tgaaatcaca
     4141 attgacatta tttttggtgt tatttattgt ataacttata aaatatttaa tatatatcca
     4201 caattcttgt tttttttttt agcctctgta catagtcatt ttgatggcag ctctcaaaac
     4261 catgtgtatg aaaattgcaa aatgggaaag ctttgacagt ctccccaaat cctattggtt
     4321 gttttccatt aaaactaatg gagttagggt cagcttggtg tttggggagt gaaggagtta
     4381 gaagggctca tcactgaaaa caaagacacc acaggccatg caggtcgtga tgcagaggca
     4441 ctgtctcaga cgtgacagct agagaccaaa agcatctgac cacagcagcc aggcccgaga
     4501 gaaaacctct gcttcctaag gcaggatgca gtgcctctgt gtgttatttt tgtagcaggt
     4561 aaagttgaaa atgtatgtgg aaaggcgtgg tgagagagtt tgatccaata cacacctgct
     4621 tttggggggg gcagttttcg ttacctggct tctgccaaca ttatataaat tatatcataa
     4681 attgatctgg aatcttattt tcttccatct aaatggaatt ttcccccata taagtcttta
     4741 gtcctaaggt cagaaaatgt actatagtgt ttattataaa ataatccata gcccctaaat
     4801 tggatggcag ggactcttgg taaaagtcac ctctcagtca taatagtatt taacagaatg
     4861 aatgcattaa aaagtaatgg gacagcttga actatgacat ttgacaggac ttcgccttac
     4921 tgacagttct tcagaaggtc tcagtataca ttcgttagaa taattcaaaa ggcaattaca
     4981 acggaaacct ttcagaggag aaaaggccac atggcatcta ggagactgcc gtatctgggc
     5041 ctctcttctt tcccatttgt ctgcccactt tggcatctcc tggagcagtg aaaataaagc
     5101 actgtccaca aagaaaagca aagtcagctt gctttgttgg cccagatatt ctggatcctc
     5161 tattgaaatg aaccagtgag gtggtttcca tggctgaaac atttcctgtg agaaaatcaa
     5221 ttgcagactg gttgagtgta ttttgttgag tgtattttgt aacatgctat ttggtccttg
     5281 tgatgtggaa tagtcatctt tatcacagca gaaacagcct ggcatgtcat gaaaatgctc
     5341 ctgttttgcc attagcaggc gtgtgctcca tggttgactg gagagctgtt tctgaagcct
     5401 tggcacagat ctggctttgt cctagtggtg tcttatcatc catgctgaga tcagacccag
     5461 gaccttgtac actccaggaa gcactctccc cctgagctct gtcctcggct aaatttattc
     5521 ttaatgtttg tttgtttgtt tgtttgtgtc cggccctgcg tctcagaatt ctgaaatacg
     5581 ccttaggtag gaaggagtca aaaaacaaat caggatttgc tttgcctgtt ctgaacccca
     5641 gcattgcatt cctgaagttc ttcttaaata cagagccctt gcgtacatcc ttgtagccct
     5701 tcccaccacc attccttttc agacctgtct ttattcacct aagcgacagt ccgttcatgt
     5761 gcccattgac atacaagtta ataggaatgg cctggggatc ctttggttag gacttttcaa
     5821 aatgattcag atgatattaa tgtcatttat aaaacctggt ttggtggtgg aatgcaggta
     5881 aatggaccaa aaatgtggag accatgggga aatagtgctc tttgaggcct ggggcccttg
     5941 tttgtttgtg tggatctggg gttggaactt catgcatgcc aggagacctt ctatcactgg
     6001 ctaccagtga cagctcagcc ccagagttgt ttcttttgaa gcttgtcaca atgcaaagag
     6061 atcctatatt agcatgcaag ttctcttttg aagtctacag cagaatttca caggcttctt
     6121 tacagctttc agccagacta aataaaaatt ccaaaccaca ctatagaagc taacctgggg
     6181 tgactgaacc aagggagaaa agaaagtaaa tgtctcattt cttgtgattg ttagcagaca
     6241 gtttatatcc ttctgattac agagcagcat gggtagtaat gaggccctcc ctccagcaca
     6301 gggcctcaca gcactggctg catttagaga actaggaccc ttccacactc cctaagaccc
     6361 agctctctgg tgatagcaaa gccctgcagg gctgagcact ttaactaagg aggtttgtga
     6421 cttttaccaa ggggatttct gtaaaatgac ttaaagaatg agtcattgct ccatgggttg
     6481 gtcaagtcct agacgtaccg gcaggtggct aagttgggtg gctttatgct tgtagcaact
     6541 ggactacaat ttgcccttct atttagacga tgcttgggta tcagatggaa aggcactgcc
     6601 ttgccatggg cacctaccag gcaaggtgcc aaagataaca aatgaaaaaa cagaaccctg
     6661 atttctctgg gctcttagaa gtcgccccgg ctcagtgttt gcctctgcct ggcacagact
     6721 ctgggctttg tcgtttggtt cttgactata cttattcaaa atggggtttt gttttgtttt
     6781 gtttgttttg ttttgtttta tgagccaggt gatgacggtg cacaccttta atcctagcac
     6841 ttgggaggca gatgcagaca gaggcagagg cagaggcaga ggcagaggca ggcagaactc
     6901 ttacaggcca gcctagtcta caaagtgagt tccaggatag ccatggctac acacacacac
     6961 acacacaacc acaaatcaac agcaacaaca ataacaaaac acatgctcat acaaactttt
     7021 ttttttaaag aatcctaagc aaaaatgcct ttcttttctc tgtctgtggc tagtccaccc
     7081 tggaggataa gacttctgac aggaacgata cacgcacgta gctgggctga ggagttaggt
     7141 tgttcttgct ttgttttcgt attacagttt cggttatagg ttagtcttgc ccaaatacag
     7201 caaagcccaa gtatctaaat ggcatccttt tatgtgtaaa actatagatg tctttcaaac
     7261 cttacttccg gacagcaact gtgtaagcta aggctatgga atactgaaaa cagtggtgga
     7321 aatgtataat tcttgccctt attctgagtt tttcaatgca aagcatgttg tatagttctg
     7381 aaaacacttg cagtgttttt gtttctgtga gcttattgtt ctgagagagc agattaataa
     7441 ctgtagtaca aaccatgact tcctatcaaa gagagaccag agaatagaaa aaaatatgtg
     7501 aagccgtcag attaactcat gtgaaaatac tctattttga tcacccggac tcttctgatt
     7561 aaagccacca gggcatgtaa ctttaaaaac aagacagtgc ctcacagtgc atagtcctgg
     7621 tctgattgca aatgtaggtc gtcagctgtt gtaactagaa acacctgcat gcagagaccc
     7681 aggctacctt ctccactgtt gggggcacac tctatagtca cagtgaatcc ggaagttcct
     7741 aatgtgcgta tcctttggga gttttttagc tgtcggccca ttatgggggc acactagttc
     7801 aagattagtg cttcagagtt ctaatcctat catcactctg aggagctgca tcactgaggc
     7861 agggtggcct ttctcagtgg agcctggccc ccatgaagca ccgtcctgtc caatggttcc
     7921 gggaaacacc atgagcctct ccaatgcttt gaaaagcact acgcatctgt ggagataatg
     7981 atcttgctcc ccccaccccg ttattcttgg tagtgagcac cacaaccaca agacacataa
     8041 acaaccccgg gaaggattgg gttgtccaga tatgtaacat gacaagagca gttaactctt
     8101 actttacatc tgtgtgctta aagttcttac agtgaccctg tcaggttcct gggagaaaag
     8161 ataacgttcc ttccagggga ctggggcgtc tgcagaggcc agggctggtt ttgactgtgt
     8221 ggaaatcgct gtgttgctgt caggacctgt tctttgttcc tattgctcaa tgttcctgtt
     8281 ttgggtgatc gtgtataaat gtacacctgc gttatttttg ctatgctgct taaagtattc
     8341 ctccatataa gtctgactgt atactttgcc taagtctttc aaaaataaaa tttatgtaaa
     8401 tgtctatttt atataaaaca tggtaaaata agaa
//
