LOCUS       XP_038964827             942 aa            linear   ROD 22-FEB-2024
DEFINITION  protein O-mannosyl-transferase TMTC1 isoform X1 [Rattus
            norvegicus].
ACCESSION   XP_038964827
VERSION     XP_038964827.1
DBLINK      BioProject: PRJNA1074393
DBSOURCE    REFSEQ: accession XM_039108899.2
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     MODEL REFSEQ:  This record is predicted by automated computational
            analysis. This record is derived from a genomic sequence
            (NC_086022) annotated using gene prediction method: Gnomon,
            supported by EST evidence.
            Also see:
                Documentation of NCBI's Annotation Process
            
            [WARNING] On Jul 22, 2024 this sequence was replaced by
            NP_001418720.1.
            
            ##Genome-Annotation-Data-START##
            Annotation Provider         :: NCBI RefSeq
            Annotation Status           :: Full annotation
            Annotation Name             :: GCF_036323735.1-RS_2024_02
            Annotation Pipeline         :: NCBI eukaryotic genome annotation
                                           pipeline
            Annotation Software Version :: 10.2
            Annotation Method           :: Best-placed RefSeq; Gnomon;
                                           cmsearch; tRNAscan-SE
            Features Annotated          :: Gene; mRNA; CDS; ncRNA
            Annotation Date             :: 02/09/2024
            ##Genome-Annotation-Data-END##
            COMPLETENESS: full length.
FEATURES             Location/Qualifiers
     source          1..942
                     /organism="Rattus norvegicus"
                     /strain="BN/NHsdMcwi"
                     /bio_material="RGD 61498"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /sex="male"
                     /tissue_type="kidney, spleen, liver"
                     /geo_loc_name="USA: Wisconsin, Milwaukee"
                     /lat_lon="43.05 N 88.04 W"
                     /collected_by="Rebecca Schilling, Melinda Dwinell"
     Protein         1..942
                     /product="protein O-mannosyl-transferase TMTC1 isoform X1"
                     /calculated_mol_wt=105994
     Region          351..425
                     /region_name="TMTC_DUF1736"
                     /note="Protein O-mannosyl-transferase TMTC, DUF1736;
                     pfam08409"
                     /db_xref="CDD:462468"
     Region          543..571
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Site            order(544,547..548,551..552,554,578,581..582,585..586,609,
                     612..613,616..617,620)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          547..798
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Region          576..603
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          608..636
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          642..670
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Site            order(643,646..647,650..651,653,677,680..681,684..685,
                     687..688,711,714..715,718..719,722)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          675..705
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          683..938
                     /region_name="LapB"
                     /note="Lipopolysaccharide biosynthesis regulator
                     YciM/LapB, contains six TPR domains and a C-terminal
                     metal-binding domain [Cell wall/membrane/envelope
                     biogenesis]; COG2956"
                     /db_xref="CDD:442196"
     Region          710..738
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          743..771
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          776..806
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Site            order(812,815..816,819..820,822,850,853..854,857..858,
                     860..861,884,887..888,891..892,895)
                     /site_type="other"
                     /note="putative protein binding surface [polypeptide
                     binding]"
                     /db_xref="CDD:276809"
     Region          812..839
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          844..878
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     Region          883..911
                     /region_name="TPR repeat"
                     /note="TPR repeat [structural motif]"
                     /db_xref="CDD:276809"
     CDS             1..942
                     /gene="Tmtc1"
                     /coded_by="XM_039108899.2:190..3018"
                     /db_xref="GeneID:362465"
                     /db_xref="RGD:1564868"
ORIGIN      
        1 mlvtrgdrgg gerapsrrpr wglvpagaaa lltgasclcy grslrgefvh ddvwaivnnp
       61 dvrpgaplrw avfandfwgk gladstshks yrplcvlsfr lnifltgmnp fyfhavnvil
      121 hclvtlvlmy tcdktvfknr glafvtallf avhpvhteav agivgradvl acllfllafl
      181 syhrsldqdc agqcfpptas pfflllslfl gtcamlvket gvtvfgvclv ydlfspshkq
      241 dklsngaicq hsprqpgspq pssqqahphr esrkqrfphr dtwggchspl ppepkssgfp
      301 vspralwslm rcltgnsnrs flltlrpflk railvisyvt vilyfrlwim ggtmplfseq
      361 dnpasfspyi ltrfltysyl lafnvwllla pitlcydwqv gsiplvetiw dvrnlatill
      421 avvmallslh cvaafkrleh kevlagllfl vfpfipasnl ffrvgfvvae rvlympsmgy
      481 cilfvhglsk lcaglsrcga tslmastvll lllfswktvk qneiwlsres lfrsgvqtlp
      541 hnakvhynya nflkdqgrnk eaiyhyktal klyprhasal nnlgtltkdm aeakmyyqra
      601 lqlhpqhnra lfnlgnllks qekteeaivl lkesikygpd fadaysslas llaeqerfke
      661 aedvyqagik ncpdssdlhn nyavflvdsg fpekavahyq qaiqlspshh vavvnlgrlh
      721 rslgensmae ewyrralqva rtaevlsplg alyyntgrhk ealevyreav slqpsqrdlr
      781 lalaqvlavm gqtkeaekit shivseeprc lecyrllsai yskqehheka leaiekalql
      841 kpkdpkvise lfftkgnqlr eqnlldkafe syeaavtldp dqaqawmnmg girhiqgsyv
      901 parvyyeral rlvpeskllk enlakldrle rrlqevrerd qt
//
