LOCUS       NM_021261                473 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus thymosin, beta 10 (Tmsb10), mRNA.
ACCESSION   NM_021261
VERSION     NM_021261.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Nemolato,S., Ekstrom,J., Cabras,T., Gerosa,C., Fanni,D., Di
            Felice,E., Locci,A., Messana,I., Castagnola,M. and Faa,G.
  TITLE     Immunoreactivity for thymosin beta 4 and thymosin beta 10 in the
            adult rat oro-gastro-intestinal tract
  JOURNAL   Eur J Histochem 57 (2), e17 (2013)
   PUBMED   23807296
  REMARK    GeneRIF: a species-specific expression of Tbeta4 and Tbeta10,
            characterized by the actual unpredictability of the expression of
            these peptides in different cells and tissues
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Tsuji,M., Monkawa,T., Yoshino,J., Asai,M., Fukuda,S., Kawachi,H.,
            Shimizu,F., Hayashi,M. and Saruta,T.
  TITLE     Microarray analysis of a reversible model and an irreversible model
            of anti-Thy-1 nephritis
  JOURNAL   Kidney Int 69 (6), 996-1004 (2006)
   PUBMED   16528249
  REMARK    GeneRIF: Thymosin beta10 may play an important role in the
            progression of kidney disease
REFERENCE   3  (bases 1 to 473)
  AUTHORS   Farkas,R.H., Qian,J., Goldberg,J.L., Quigley,H.A. and Zack,D.J.
  TITLE     Gene expression profiling of purified rat retinal ganglion cells
  JOURNAL   Invest Ophthalmol Vis Sci 45 (8), 2503-2513 (2004)
   PUBMED   15277470
REFERENCE   4  (bases 1 to 473)
  AUTHORS   Lin,S.C. and Morrison-Bogorad,M.
  TITLE     Cloning and characterization of a testis-specific thymosin beta 10
            cDNA. Expression in post-meiotic male germ cells
  JOURNAL   J Biol Chem 266 (34), 23347-23353 (1991)
   PUBMED   1744129
REFERENCE   5  (bases 1 to 473)
  AUTHORS   Lugo,D.I., Chen,S.C., Hall,A.K., Ziai,R., Hempstead,J.L. and
            Morgan,J.I.
  TITLE     Developmental regulation of beta-thymosins in the rat central
            nervous system
  JOURNAL   J Neurochem 56 (2), 457-461 (1991)
   PUBMED   1988550
REFERENCE   6  (bases 1 to 473)
  AUTHORS   Goodall,G.J. and Horecker,B.L.
  TITLE     Molecular cloning of the cDNA for rat spleen thymosin beta 10 and
            the deduced amino acid sequence
  JOURNAL   Arch Biochem Biophys 256 (1), 402-405 (1987)
   PUBMED   3606131
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000004.1.
            
            On Jul 15, 2022 this sequence version replaced NM_021261.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: CB732472.1, CB739644.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-64                JAXUCZ010000004.1  106569077-106569140 c
            65-176              JAXUCZ010000004.1  106568653-106568764 c
            177-473             JAXUCZ010000004.1  106568080-106568376 c
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="4"
                     /map="4q32"
     gene            1..473
                     /gene="Tmsb10"
                     /gene_synonym="Ptmb10; THYb10"
                     /note="thymosin, beta 10"
                     /db_xref="GeneID:50665"
                     /db_xref="RGD:62022"
     exon            1..64
                     /gene="Tmsb10"
                     /gene_synonym="Ptmb10; THYb10"
                     /inference="alignment:Splign:2.1.0"
     exon            65..176
                     /gene="Tmsb10"
                     /gene_synonym="Ptmb10; THYb10"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..211
                     /gene="Tmsb10"
                     /gene_synonym="Ptmb10; THYb10"
                     /note="prothymosin beta 10"
                     /codon_start=1
                     /product="thymosin beta-10"
                     /protein_id="NP_067084.1"
                     /db_xref="GeneID:50665"
                     /db_xref="RGD:62022"
                     /translation="MADKPDMGEIASFDKAKLKKTETQEKNTLPTKETIEQEKRSEIS
                     "
     exon            177..473
                     /gene="Tmsb10"
                     /gene_synonym="Ptmb10; THYb10"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tgtctcttgc tgcagcaacg cgagtgggag tacctggagc gcgagctcgg aacgagaatc
       61 cacgagttgt aagaaaatgg cagacaagcc ggacatgggg gaaatcgcca gcttcgataa
      121 ggccaagctg aagaaaaccg agacgcagga gaagaacacc ctgccgacca aagagaccat
      181 tgaacaggaa aagaggagtg aaatctccta aaagcctagg aagatttccc caccccaccc
      241 cttcatctcc aagaaccccc tcgtgatgtg gaggaagagc cacctgcaag atggacgcga
      301 gccacaagct gcactgtgaa cccgggcact ccgcgccgat gccaccggcc cgtgggtctc
      361 tgaaggggac ccccccacta atcggactgc caaatttcac cggtttgccc agggatatta
      421 tagaaaatta tttgtatgat tgatgaaaat aaaacacacc tcgtggcatg gtt
//
