LOCUS       NM_001105882            2590 bp    mRNA    linear   ROD 29-MAR-2024
DEFINITION  Rattus norvegicus transmembrane serine protease 7 (Tmprss7), mRNA.
ACCESSION   NM_001105882 XM_001066379 XM_221464
VERSION     NM_001105882.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2590)
  AUTHORS   Szabo,R., Netzel-Arnett,S., Hobson,J.P., Antalis,T.M. and
            Bugge,T.H.
  TITLE     Matriptase-3 is a novel phylogenetically preserved
            membrane-anchored serine protease with broad serpin reactivity
  JOURNAL   Biochem J 390 (Pt 1), 231-242 (2005)
   PUBMED   15853774
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1.
            
            On Oct 15, 2009 this sequence version replaced NM_001105882.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26360190.2754612.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760393, SAMN16418971
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-48                JAXUCZ010000011.1  68591605-68591652
            49-256              JAXUCZ010000011.1  68593989-68594196
            257-387             JAXUCZ010000011.1  68598167-68598297
            388-455             JAXUCZ010000011.1  68599937-68600004
            456-649             JAXUCZ010000011.1  68601293-68601486
            650-688             JAXUCZ010000011.1  68603246-68603284
            689-917             JAXUCZ010000011.1  68604048-68604276
            918-1048            JAXUCZ010000011.1  68605491-68605621
            1049-1161           JAXUCZ010000011.1  68607428-68607540
            1162-1268           JAXUCZ010000011.1  68611539-68611645
            1269-1405           JAXUCZ010000011.1  68616228-68616364
            1406-1513           JAXUCZ010000011.1  68617812-68617919
            1514-1624           JAXUCZ010000011.1  68621045-68621155
            1625-1741           JAXUCZ010000011.1  68621961-68622077
            1742-1913           JAXUCZ010000011.1  68622923-68623094
            1914-2182           JAXUCZ010000011.1  68624360-68624628
            2183-2319           JAXUCZ010000011.1  68625622-68625758
            2320-2590           JAXUCZ010000011.1  68627207-68627477
FEATURES             Location/Qualifiers
     source          1..2590
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q21"
     gene            1..2590
                     /gene="Tmprss7"
                     /note="transmembrane serine protease 7"
                     /db_xref="GeneID:288118"
                     /db_xref="RGD:1304655"
     CDS             1..2490
                     /gene="Tmprss7"
                     /note="matriptase-3; transmembrane protease, serine 7"
                     /codon_start=1
                     /product="transmembrane protease serine 7"
                     /protein_id="NP_001099352.2"
                     /db_xref="GeneID:288118"
                     /db_xref="RGD:1304655"
                     /translation="MDKEKSDPSCKSSDLKISNISIQVVSVPGKLPGRRLPRKPIGKA
                     RPRKQPKKRAPFWNVQNKIILFTVFLFILAVTAWTLLWLYISKTDSKDAFYFVGMFRI
                     TNIEFLPEYRQKESREFLSMAKTVQQVVNLVYTTSAFSKFYKQSVVADVSSNNKGGLL
                     VHFWIVFVMPHAKGHIFCEECVAAILKDSIQTSITNRTSVGTLQGLAVDMDSVVLNAG
                     LRSDYSSAVGSDNGCSQYFYADHLTLRYPLEISATSGQLMCHFKLVAIVGYLIRLSIE
                     SIQLEADNCITDSLTVYDSLLPIRSAILYRICEPTRTLMSFVSTNNLMLVTLKSPYVR
                     RLAGIRAYFEVIPEQKCENTILVKEINSFEGKISSPYYPSYYPPKCKCNWTFQTSLST
                     LGIALKFHNYSITKKSMKGCEHGWWEINEHMYCGSYMDHETIFRVPSPLVHIQLQCSS
                     RLSDKPLLVEYGSYNISQPCPAGSFRCSSGLCVPQAQRCDGVNDCFDESDELFCVTAK
                     PACNTSIFRQHGPLVCDGFQDCEDGQDEQNCTRSIPCTNRTFKCGNDICFRKQNAQCD
                     GIVDCPDRSDEEGCGCSRSSPFLHRVVGGSDSQEGTWPWQVSLHFVGSAHCGASVISR
                     EWLLSAAHCFHGNRLSDPTPWTAHLGMYVQGNAKFVSPVRRIVVHEYYNSQTFDYDIA
                     LLQLSIAWPETLRQLIQPICIPPVGQRVRSGEKCWVTGWGRRHEADSKGSPILQQAEV
                     ELIDQTVCVSTYGIITSRMLCAGVMSGKSDACKGDSGGPLSCRRKSDGKWILTGIVSW
                     GYGCGRPNFPGVYTRVSNFVPWIHKYVPSLL"
     exon            1..48
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            49..256
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            257..387
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            388..455
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            456..649
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            650..688
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            689..917
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            918..1048
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            1049..1161
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            1162..1268
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            1269..1405
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            1406..1513
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            1514..1624
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            1625..1741
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            1742..1913
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            1914..2182
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            2183..2319
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
     exon            2320..2590
                     /gene="Tmprss7"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 atggacaaag aaaaaagtga tccttcctgc aagtcctcag acctcaaaat atccaacatc
       61 tccatccagg tggtcagtgt cccagggaag ctaccaggga gaagactacc tcgaaaaccc
      121 attggcaaag ccaggccccg caagcagcct aagaagagag ctcccttttg gaatgttcaa
      181 aataagatca ttctcttcac agtattttta ttcatcctgg cagtcacagc ctggacactt
      241 ctatggctct atatcagtaa gacagacagc aaagacgcct tttattttgt tgggatgttc
      301 cgcatcacca acattgagtt tcttcccgag taccggcaga aggagtctag ggaatttctc
      361 tccatggcaa agacagtaca gcaagtggta aaccttgttt atacaacatc tgctttctcc
      421 aaattttata agcagtctgt ggttgcagat gtcagcagta acaacaaagg cggtctcctg
      481 gtccactttt ggattgtgtt tgtcatgccc catgccaagg gccacatctt ctgtgaggaa
      541 tgtgtggcag ccatcttgaa ggactccatc caaaccagta tcacaaaccg cacctctgtg
      601 gggaccttgc agggtctggc cgtggatatg gactctgtgg tattaaatgc tgggctccgg
      661 tcggattact cttcagcggt aggatctgac aatggctgct cccagtactt ctatgcagat
      721 catctgaccc tccgctaccc tctggagatt tccgcaactt cgggacagct aatgtgtcac
      781 ttcaagctgg tggccatagt gggttatctg attcgtctct caattgagtc cattcaatta
      841 gaagctgaca actgtattac agactcccta actgtttacg actccctctt gccaatccgg
      901 agtgccattc tatacagaat ctgtgaaccc acaaggacac taatgtcctt cgtttctaca
      961 aataatctca tgttggtgac actgaagtct ccttatgtac ggaggctggc agggatccgg
     1021 gcatattttg aagtcattcc agaacaaaaa tgtgaaaata caatactggt caaagaaatc
     1081 aacagctttg aagggaaaat ctcaagtccc tattacccaa gctactatcc cccgaaatgc
     1141 aagtgcaact ggacatttca gacttctcta tcaactcttg gcatagccct aaaattccac
     1201 aactattcca taactaagaa gagtatgaaa ggctgtgagc atggctggtg ggaaattaat
     1261 gaacacatgt actgtggctc ctacatggat catgagacga ttttccgggt gcccagcccc
     1321 ctggtccaca tccagctcca gtgcagttcc aggctttcag acaagccact tttggtagaa
     1381 tatggcagtt acaacatcag tcaaccttgt cctgctggat cttttagatg ctcctccggt
     1441 ttatgtgtcc ctcaggccca gcgctgtgat ggagtgaatg actgttttga tgaaagtgat
     1501 gaacttttct gtgtgactgc aaaacctgcc tgcaacacca gcatcttccg gcagcacggc
     1561 cccctggtct gtgatggctt ccaggactgt gaggacggcc aggatgagca gaactgcact
     1621 aggagcatcc catgcaccaa caggaccttt aaatgtggca atgacatttg cttcagaaag
     1681 caaaatgccc aatgcgatgg tatagtggac tgtccagaca gaagtgacga ggagggctgc
     1741 ggctgtagca gaagttctcc cttccttcac cgcgtcgttg ggggttccga ttcccaggag
     1801 ggaacctggc catggcaggt cagcctccac tttgttggat cagcccactg tggtgcctca
     1861 gtcatctcca gagagtggct tctctctgca gcccactgtt tccacggaaa caggctgtcc
     1921 gaccccaccc catggactgc tcaccttggg atgtacgtgc aggggaacgc caagtttgtc
     1981 tctccagtaa gaaggattgt ggtccacgaa tactacaaca gccagacttt tgattatgac
     2041 attgctttgc tgcagctcag catagcctgg cctgaaaccc tgagacagct cattcaacct
     2101 atatgtattc ctccagttgg ccagagagtg cgcagtgggg agaagtgctg ggtgacgggc
     2161 tgggggcgaa ggcatgaagc agacagtaaa ggctccccca ttttgcagca agcggaggta
     2221 gagctcatag atcaaaccgt ctgtgtttcc acctacggga tcatcacctc tcggatgctc
     2281 tgtgcagggg ttatgtctgg caagagcgat gcctgcaaag gagattcagg tggacctttg
     2341 tcttgtcgaa gaaagagtga tgggaaatgg attctgaccg gcattgttag ctggggatat
     2401 ggatgtggaa gaccaaattt tcctggtgtt tacacacggg tgtcaaactt tgtcccctgg
     2461 attcataagt atgtcccttc tcttttgtaa ctgtacaaga tgaattttta actgtgactt
     2521 tgatatggga ctgtgctaga tccttgtaaa agaatgtatt atcaataaaa ttaatcattt
     2581 tttcaacaga
//
