LOCUS       NM_001127528            3128 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane serine protease 13 (Tmprss13),
            mRNA.
ACCESSION   NM_001127528 XM_001068384 XM_236201
VERSION     NM_001127528.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 3128)
  AUTHORS   Madsen,D.H., Szabo,R., Molinolo,A.A. and Bugge,T.H.
  TITLE     TMPRSS13 deficiency impairs stratum corneum formation and epidermal
            barrier acquisition
  JOURNAL   Biochem J 461 (3), 487-495 (2014)
   PUBMED   24832573
REFERENCE   2  (bases 1 to 3128)
  AUTHORS   Bastos-Amador,P., Royo,F., Gonzalez,E., Conde-Vancells,J.,
            Palomo-Diez,L., Borras,F.E. and Falcon-Perez,J.M.
  TITLE     Proteomic analysis of microvesicles from plasma of healthy donors
            reveals high individual variability
  JOURNAL   J Proteomics 75 (12), 3574-3584 (2012)
   PUBMED   22516433
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from
            JAXUCZ010000008.1.
            
            On Nov 27, 2020 this sequence version replaced NM_001127528.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC166801.1, SRR26643299.34890.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760389 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-43                JAXUCZ010000008.1  54522497-54522539
            44-389              JAXUCZ010000008.1  54531764-54532109
            390-494             JAXUCZ010000008.1  54533040-54533144
            495-617             JAXUCZ010000008.1  54535655-54535777
            618-747             JAXUCZ010000008.1  54536746-54536875
            748-840             JAXUCZ010000008.1  54539257-54539349
            841-884             JAXUCZ010000008.1  54540232-54540275
            885-1047            JAXUCZ010000008.1  54541285-54541447
            1048-1220           JAXUCZ010000008.1  54542244-54542416
            1221-1319           JAXUCZ010000008.1  54546142-54546240
            1320-1462           JAXUCZ010000008.1  54548072-54548214
            1463-1615           JAXUCZ010000008.1  54548370-54548522
            1616-3128           JAXUCZ010000008.1  54549161-54550673
FEATURES             Location/Qualifiers
     source          1..3128
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..3128
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /note="transmembrane serine protease 13"
                     /db_xref="GeneID:300682"
                     /db_xref="RGD:1310872"
     exon            1..43
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     CDS             23..1642
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /note="transmembrane protease, serine 13"
                     /codon_start=1
                     /product="transmembrane protease serine 13"
                     /protein_id="NP_001121000.1"
                     /db_xref="GeneID:300682"
                     /db_xref="RGD:1310872"
                     /translation="MDRGSHRNASPARPSPQASPARASPQASPARTPPPQASPARASP
                     PQASPARASPARASPVRASPARAPPSRSSSGRSSSARSASTTSSPTRVYLVRAIPVGT
                     VIRASPARSAPATRATRESPGLSFPKFSWQETQRQLPLIGCVLLLISLVISLILLFYF
                     WRGHTGIKYKEPLESCPKHAVRCDGVVDCKMKSDELGCVRFDWDKSLLKVYSGSSGEW
                     LPVCSSSWNDTDSERTCQQLGFDSAYRTTEVAHRDVTSSFLLSEYNSTIQESLTRSEC
                     PSRRYVSLQCAHCGLRAMTGRIVGGALTSESKWPWQVSLHFGTTHICGGTLIDAQWVL
                     TAAHCFFVTREKILEGWKVYAGTSNLHQLPEAASISQIIINGNYTDEQDDYDIALVRL
                     SKPLTLSAHIHPACLPLHGQTFGLNETCWITGFGKTKETDEKTSPFLREVQVNLIDFK
                     KCNDYLVYDSYLTPRMMCAGDLRGGRDSCQGDSGGPLVCEQNNRWYLAGVTSWGTGCG
                     QKNKPGVYTKVTEVLPWIYRKMESEVRFRKS"
     exon            44..389
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            390..494
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            495..617
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            618..747
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            748..840
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            841..884
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            885..1047
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            1048..1220
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            1221..1319
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            1320..1462
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            1463..1615
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..3128
                     /gene="Tmprss13"
                     /gene_synonym="RGD1310872"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggaagaagca acctcttaca ccatggacag aggcagccac cggaatgctt ctccagcaag
       61 gccatctcct caggcttctc cagcacgggc atctcctcag gcttccccag caaggacacc
      121 tcctcctcag gcttccccag caagggcatc tcctcctcag gcttctccag cacgggcatc
      181 tccagcacgg gcatctccag tccgggcatc tccagcccgg gcaccacctt ccaggtcatc
      241 gtcaggcaga tcatcatctg cccggtcagc ctccacaaca tcctccccaa cgagagtgta
      301 ccttgttaga gcaataccag tggggactgt catccgggca tctcctgcca ggtcagcacc
      361 agccaccagg gccaccaggg agagcccagg tctcagtttc cccaagttct cctggcagga
      421 gacccagaga cagctgccac tcatcgggtg tgtcctcctc ctcatcagcc tggtgatctc
      481 actcatcctt ctcttctact tctggcgagg ccacacaggg atcaagtaca aagagccatt
      541 ggagagctgc cccaagcatg cagttcgctg tgatggagtg gtggattgca aaatgaagag
      601 tgatgagctg ggctgtgtca ggttcgactg ggacaagtcc ctcctcaaag tctactctgg
      661 gtcttctggt gagtggcttc ctgtctgcag cagcagttgg aacgacaccg actccgagag
      721 gacctgccag cagctgggct ttgacagtgc ctaccgaaca actgaggtgg cccataggga
      781 cgtcaccagc agcttcttac tctccgaata caactccacc atccaggaaa gcctcaccag
      841 gtcggaatgt ccttcccggc gatacgtctc cctccagtgt gcccactgtg gtctgagagc
      901 tatgaccggg cggatcgtgg gaggggctct gacctcggag agcaagtggc cctggcaagt
      961 tagcctgcac ttcggcacca cccacatctg tgggggcacg ctcattgatg cccagtgggt
     1021 gctcaccgct gcccactgtt tctttgtgac ccgggagaag attctggagg ggtggaaggt
     1081 gtacgcaggc accagcaact tgcaccagct gcctgaggct gcctctatct cccagatcat
     1141 catcaacggc aactacaccg atgaacagga tgactatgac atcgccctcg tgaggctgtc
     1201 caagcccttg accctgtcag ctcacatcca ccctgcctgc ctccctttgc atgggcagac
     1261 cttcggcctc aatgagacct gttggatcac tggctttggc aaaaccaagg aaacagatga
     1321 gaagacatct cccttcctcc gagaggttca ggtcaacctc atcgacttca agaagtgcaa
     1381 tgactacttg gtctatgaca gttaccttac cccaaggatg atgtgtgcgg gggaccttcg
     1441 aggaggcagg gactcctgcc agggagacag tggaggaccc ctcgtctgtg agcagaacaa
     1501 ccgctggtac ctggcaggag tcaccagctg gggcacaggc tgtggccaga aaaacaagcc
     1561 tggggtgtac accaaagtga cagaagtact tccctggatc tatagaaaga tggagagtga
     1621 ggtacgtttc cggaaatctt agccatgccc tcctcacatt ggtgactgct atgaagatcc
     1681 tggccaaagg gattggccat ttgcaacacc tggaccagtg accaccaggc ctctttgttc
     1741 attccacctc tgctgcttac tgtctctgtg atagtgtcta agtggttgtg tgtgtgtgtg
     1801 tgtgtgtgtg tgtgtgtgtg tgtgtgtgtg tgtgtcttac tatttttaca agttcttcag
     1861 aaaacaggaa aactcttctc agaatcccag gctggaaatc tggagttaag agtttgggca
     1921 ccaggtgtgt ccctaagagt ccataagtgg aggtggagcc aaaaatgagc ccaggaaggg
     1981 cttggaacat gacagcagca gttgtcgctc ttctgactcc aacttgaaga ccagcttggt
     2041 ttggtcagac cctcagcagt cagtgacacc attgctgtgc tggggtagca taaagttttg
     2101 tcagaggctg tcttttcagt gcctggacca tctgtcccct gtggaaagcc attcccatct
     2161 gtgctgcaag catccggtct ctcagtccct tgtagctgcc atggattcca gagctgggct
     2221 ctgctgtagc tgtccatctc tgggtgatga ctgtgattca ggcttgtgta tgtttggtcg
     2281 caagctgttg gggtggattt tatttttata tttaaaatat agaaatagat gtaactttaa
     2341 agagtctcca aaattcctag ggaccttggg agtttttgca tgaatcacct catgaactcc
     2401 aggggacctg tgggagatgt accgctgtag catcctgtga tagattactg gtttaggaaa
     2461 tcaggagaag tgccctgatg aagtcctcag gacagacatc tccaagtcgg tgtagagact
     2521 agggaccttt gaaatactca gggaagaaaa ccctcgattg gattgggttg atcaataaat
     2581 ccagtgcata ctgatctggc ctccaaggac tctagccagt cagaagatgt gtgcactgcc
     2641 ctggttcgcc tccacctctg aggaaatcta cacagacagc gtccattaca cccaagggct
     2701 gactgtgaag tttgcttctg tcatccttca tcgttcagcc ttgtactgac tcaaaaggcc
     2761 ataaagagaa agcaagaact gtcctcagaa cctctaaaca gtccttctgg gcagcctaag
     2821 ttgaccatgc tcctggtctt ccctgggcct tttctcttgg tcacctgctg ttcctcagct
     2881 ccactctctt caaccttccg gtgggcctac ctgacctctt gtgatactga gtctcagagg
     2941 caagttcaag gagatcagac cagttcagga cagctcagga catctggagg tagctggagt
     3001 gattgggcag catcagacag ggctggaaca ctagggaatc tcttcaaggc tgggaaggag
     3061 gcaggcagca tccacgtctg cagaagatcc cagcaatgag cttccataat aaaagtgtgt
     3121 ggcacaaa
//
