LOCUS       NM_001008554            2698 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane protease, serine 11G (Tmprss11g),
            mRNA.
ACCESSION   NM_001008554 XM_223305
VERSION     NM_001008554.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2698)
  AUTHORS   Behrens,M., Buck,F. and Meyerhof,W.
  TITLE     Substrate specificity of rat DESC4, a type II transmembrane serine
            protease
  JOURNAL   Protein Pept Lett 16 (1), 1-6 (2009)
   PUBMED   19149666
  REMARK    GeneRIF: The identified cleavage-sites are typical for trypsin-like
            serine proteases.
REFERENCE   2  (bases 1 to 2698)
  AUTHORS   Behrens,M., Bufe,B., Schmale,H. and Meyerhof,W.
  TITLE     Molecular cloning and characterisation of DESC4, a new
            transmembrane serine protease
  JOURNAL   Cell Mol Life Sci 61 (22), 2866-2877 (2004)
   PUBMED   15558215
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AJ617528.1.
            
            On Dec 17, 2004 this sequence version replaced XM_223305.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AJ617528.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN16676784,
                                           SAMN16676786 [ECO:0000350]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..2698
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="W"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p21"
     gene            1..2698
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /note="transmembrane protease, serine 11G"
                     /db_xref="GeneID:289546"
                     /db_xref="RGD:1306446"
     exon            1..75
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     CDS             68..1321
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /function="transmembrane serine protease"
                     /note="serine protease Desc4"
                     /codon_start=1
                     /product="transmembrane protease serine 11G"
                     /protein_id="NP_001008554.1"
                     /db_xref="GeneID:289546"
                     /db_xref="RGD:1306446"
                     /translation="MYQPGILGRRKRVCKPWTVALTTTAALLALAVLIGLLVYFLVYE
                     EKTHYYQASFWIPSIKYSSDLSEEQSKLQINLKQKINNEIDVIFQRSSLKHHYVKSQV
                     VNFRPSNDGVKADILIKFQIPRKNADTLRSEADSILNKKLQSSQSFLKRDISLPYLRE
                     MNAAQAEHILNSNCGLGMEYPRIARIADGKPAGSNSWPWQSSLQVEGIHLCGASLIGS
                     QWLVTSAHCFDNYKNPKLWTVSFGRTLGNPLTTRKVESIIIHENYAAHKHDDDIAVVK
                     LSSPVLFSENLRTVCLPEATFQVLPKSKVFVTGWGALKANGPFPNSLQEVEIEIISND
                     VCNQVNVYGGAISSGMICAGFLTGKLDACEGDSGGPLVISDNRNKWYLLGIVSWGIDC
                     GKENKPGIYTRVTHYRNWIKSKTNI"
     exon            76..197
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     exon            198..316
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     exon            317..384
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     exon            385..545
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     exon            546..584
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     exon            585..756
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     exon            757..1016
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     exon            1017..1159
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
     exon            1160..2698
                     /gene="Tmprss11g"
                     /gene_synonym="Desc4; RGD1306446"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctcatttgac agggatcaca cacagagcag cgtggaggtg gagaagctcg ccttccccac
       61 ggtgacgatg tatcagccag gaatcctggg tagaagaaaa cgtgtctgca aaccctggac
      121 agttgccctc accaccacag ctgctctgtt ggctttggca gtgctcatcg gtctccttgt
      181 ttactttttg gtgtatgaag agaagactca ttactaccag gcctcctttt ggattcccag
      241 tattaaatat agctcagatt tgtccgaaga gcagtcaaaa ttgcagatta acctgaaaca
      301 aaaaatcaac aatgagatag atgtgatatt tcaaagatcc agtttaaagc atcattatgt
      361 caaatctcaa gttgtcaact ttcggcccag taatgatggt gtgaaagcag acatactgat
      421 taaatttcag attccccgta agaatgcgga tactttaaga agtgaagctg atagcatttt
      481 gaataagaag ttgcagtcct cccagagctt cttgaagaga gacatttcct taccttatct
      541 tagagaaatg aatgcagcac aagcagaaca tattctaaac agcaactgtg gcttgggaat
      601 ggagtaccca cgcatagcaa ggatcgctga cggcaaacct gcaggctcaa attcttggcc
      661 atggcaaagc agcctgcaag tggaaggcat tcacctctgt ggtgcttctc tcattggctc
      721 ccagtggctt gtgacctctg ctcactgctt tgacaattac aaaaacccca aactgtggac
      781 agtaagtttt ggaagaaccc ttggcaatcc actgaccaca cggaaggtgg agtccatcat
      841 cattcacgag aactacgcag cccacaaaca cgatgacgat atcgctgtgg tcaagctctc
      901 cagcccggtg ctcttttctg aaaatttgcg cacagtctgt ctccctgagg ctacttttca
      961 agtcttgccg aagagtaaag tgtttgtcac tggatgggga gcactgaaag cgaatggtcc
     1021 ctttcccaat tctctgcaag aggttgaaat agagatcata agtaatgatg tatgtaacca
     1081 agttaatgta tatggtggtg ctatatcatc aggaatgata tgtgctggat tcctgacagg
     1141 aaaactggat gcctgtgagg gtgattctgg agggcctctg gttatctcag ataatagaaa
     1201 taagtggtat cttcttggaa ttgttagttg gggaatagac tgtggaaaag aaaacaagcc
     1261 cggaatttac accagagtga ctcactatcg gaactggatt aaatctaaaa ctaacatcta
     1321 atgcaacagc caccccttta ttcaacctgg agtgtcaccc actgcatctg gcaaaccgta
     1381 ttccataccc actgccatgt gcgtcctcat cgagctcaag atgcacatga gtatgggaca
     1441 gtgacctccc tcttaaatca gaaggagata gactttcttt cacatcagtg gaagggttcc
     1501 gttgactatg aacacataag atgctgtctg cttcacaaag atctaccatt ctgccaagtg
     1561 tctgattacc tccctgctca cctctgttct ccaacctcat tcgttttcaa cttatactaa
     1621 tctggaagtt gaataagtac taactgtcca gcctccctct gcttttctca agagatgact
     1681 tccttctctg attcctctat agtttttgtc ttcttcatct aaaagatgaa gggtgttcac
     1741 tggaaggttc acccctgact ggacaggcca tgttagtctt agtcagtggt gacacagtga
     1801 cgaaggaaac actggatatg aggctaggac tgaggagatg gcaatgagca ggtccgttcc
     1861 ttttcatctt cagatatgca ttcagctttt ctctgaaatt catatttata tttgtgcata
     1921 ttttattttc tttacacaat ttagctgatg tgtattttta agcggttcac ccacccatat
     1981 ttttttaata acatgagatg aatgatagac attccttagt ataaatacct ttccgtactt
     2041 gcaaattcaa agtgcttttt cttgtccctt ttattagcaa aatgtaaatg agcaagaatc
     2101 taaaaaagtt actttcagct ccatctccaa aatgagggat gtttcaacac ttgtgtaaat
     2161 ttatttttca attgtatgtt attttatttt aattcacttt atttaaacag cattattttc
     2221 aactagattt tgaataatta agtacctgta taatggagag tcaacataaa tgaattctaa
     2281 gaaaatataa acatctgaca tgtgacgcta aactaccagt acatattcat aaaatacttg
     2341 aaagaagata tcagtgaaga tggattaaat agtgcattct gcaatgggac atttatataa
     2401 atcattcaaa taatctggaa agcatcttta gaattcttag tttgaatgat aaaattgtca
     2461 ttttcatatg tatttagttg catattttat aatatctcat gtgaatatat accagtatca
     2521 aaaccgaact cagattcact ctgtgcattg gaatctttat cctcctttta tcattgttaa
     2581 attatgtgct gtcttaagtt tttattttgg ttttgtaata agtaaaatct tacactgtac
     2641 atttatgata ataaaccaaa ttccttctct ctgagtagtc actggaagtg agatgtta
//
