LOCUS       NM_001412525            4068 bp    mRNA    linear   ROD 31-MAR-2024
DEFINITION  Rattus norvegicus transmembrane protease, serine 11C (Tmprss11c),
            transcript variant 1, mRNA.
ACCESSION   NM_001412525
VERSION     NM_001412525.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4068)
  AUTHORS   Stallmach,R. and Gloor,S.M.
  TITLE     Neurobin/TMPRSS11c, a novel type II transmembrane serine protease
            that cleaves fibroblast growth factor-2 in vitro
  JOURNAL   Biochem J 412 (1), 81-91 (2008)
   PUBMED   18215125
REFERENCE   2  (bases 1 to 4068)
  AUTHORS   Puente,X.S. and Lopez-Otin,C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-104               JAXUCZ010000014.1  22136865-22136968
            105-220             JAXUCZ010000014.1  22144716-22144831
            221-339             JAXUCZ010000014.1  22153378-22153496
            340-407             JAXUCZ010000014.1  22165079-22165146
            408-568             JAXUCZ010000014.1  22169452-22169612
            569-607             JAXUCZ010000014.1  22181903-22181941
            608-779             JAXUCZ010000014.1  22185550-22185721
            780-1039            JAXUCZ010000014.1  22187245-22187504
            1040-1182           JAXUCZ010000014.1  22188501-22188643
            1183-4068           JAXUCZ010000014.1  22192427-22195312
FEATURES             Location/Qualifiers
     source          1..4068
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p21"
     gene            1..4068
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /note="transmembrane protease, serine 11C"
                     /db_xref="GeneID:408213"
                     /db_xref="RGD:1302967"
     exon            1..104
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     CDS             49..1344
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /note="isoform 1 is encoded by transcript variant 1;
                     airway trypsin-like 3"
                     /codon_start=1
                     /product="transmembrane protease, serine 11C isoform 1"
                     /protein_id="NP_001399454.1"
                     /db_xref="GeneID:408213"
                     /db_xref="RGD:1302967"
                     /translation="MARGQPRRSEEPWTALRNRTECKTKIKLTKCGKITLGILTAVIA
                     AVVIGLIAYFAACGKTPFYYHVSFKVNNIDYDSKFAKPYSQEYMDLNKRIVSLMNETF
                     HESKLRKQYVKAHTVQVSKAKGKVVIHGVLKFKSCYKNNVEKFWDSVETILYQKLKSQ
                     TRLLIDSSSFKFSDIAMPIAEDLLNTCCGRRTITPGGHKVAGGQDAEEGEWPWQASLQ
                     QNNVHRCGATLISNSWLITAAHCFVRSANPKDWKVSFGFLLSKPQAQRAVKSIVIHEN
                     YSYPAHNNDIAVVRLSSPVLYENNIRRACLPEATQKFPPNSDVVVTGWGTLKSDGDSP
                     NILQKGRVKIIDNKTCNSGKAYGGVITPGMLCAGFLEGRVDACQGDSGGPLVSEDSKG
                     IWFLAGIVSWGDECALPNKPGVYTRVTHYRDWISSKTGL"
     exon            105..220
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     exon            221..339
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     exon            340..407
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     exon            408..568
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     exon            569..607
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     exon            608..779
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     exon            780..1039
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1040..1182
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
     exon            1183..4068
                     /gene="Tmprss11c"
                     /gene_synonym="Hatl3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agctaaatag gtggagggtg actgtgccac gcagcactca aggggaagat ggcaagggga
       61 cagcctcgga ggagcgaaga gccatggaca gccttgcgga acagaacaga gtgcaaaaca
      121 aagataaaac tcacaaagtg tggaaagata accctaggca tcttaacggc ggtgatcgct
      181 gcggtagtaa ttggactcat tgcctatttt gccgcctgcg gaaaaacacc tttctactac
      241 catgtcagct ttaaggttaa caacattgac tatgacagca aatttgccaa gccatactct
      301 caggaataca tggacctaaa taaaaggata gtgtctttga tgaatgaaac atttcatgaa
      361 tcaaaactga gaaaacagta tgtcaaagct cacactgtgc aagtcagcaa agccaaaggg
      421 aaggtggtga tacatggtgt gctgaagttt aaatcctgtt ataaaaataa cgtagaaaaa
      481 ttctgggaca gcgtcgagac cattttgtat cagaaactca aaagccaaac cagattactt
      541 atagattctt cctcttttaa gttttcagac attgcaatgc caatagcaga agatcttctc
      601 aacacgtgtt gtggacgacg cacaattact cccggaggcc acaaagtagc aggaggccag
      661 gacgctgagg agggagagtg gccctggcaa gctagccttc aacagaacaa tgtccaccga
      721 tgcggagcca ctctgatcag taactcctgg ctgatcacgg ctgctcactg tttcgtacgg
      781 tctgcaaatc ccaaagactg gaaagttagc tttgggtttc ttctaagtaa accgcaagca
      841 caacgggctg tgaagagtat tgtaatccat gagaactaca gctaccctgc gcacaataat
      901 gacatagctg ttgtgcgtct gtcttcgcca gtattatacg aaaacaacat ccgaagggct
      961 tgtctaccag aagctactca gaagttccca cccaactcag atgtagtggt cactggatgg
     1021 ggcacgttaa agtcagatgg agacagtcct aatatactcc agaaaggaag agtgaagatt
     1081 atagataata agacttgtaa tagcggaaag gcatacggtg gagtgatcac acctggaatg
     1141 ctgtgtgctg ggttcttgga gggccgtgtt gatgcctgcc agggtgattc tggtggacca
     1201 ctggttagtg aagattctaa gggcatctgg ttccttgctg gtattgtaag ctggggagat
     1261 gaatgtgcac ttccaaacaa gcctggtgtc tacactcggg tgacacacta tcgagactgg
     1321 atctcatcca aaactggtct ctagtgtact tgttctctgt agattcaagc tcaatggtta
     1381 cacatctgtt aaataagttt ataatcccca aaccacattc ttagatattt ctcctggtct
     1441 acacatttaa atataaaatt taaaggcata aaggtattgt atcacgtgag cactagttat
     1501 agatgtttct aattgtataa gccttcttct gctgaccagt tcatgaattc cccagaatca
     1561 aggtgtttga ggatgaagtc tagtaccttg taataatatc acccataaga gttactcaag
     1621 aaatatatct attttctttc tggtttctgt gtcaaaacta attattctaa ttcttcctca
     1681 tcttaaggga tagaaatcga aatgataacc ccatggagtg cattgataga ctgcagtgtt
     1741 tatggactta tcattctctc tttactgtga aattgaagtc agaaggtggt tctcttcaac
     1801 agtagtagca ttgcccaaag gcatagtaat tttgtttcaa tacgtggctt taattcatga
     1861 tgcaaataat gccacattgt tttccagctc ttaaaatgtc tcaatagtac aaattagcaa
     1921 caagataaac aatgtaaaaa attgttttca tgtcactctg attttgccca taaaaagtca
     1981 ttctagtgga gggtacaggt gtctgtaaat tctgctactc agttgccatt actccaaaaa
     2041 cgttatctaa tccaaatgct tcctcagaca ggagtccatc cctgtctcta tttctctgct
     2101 tcatcattaa caatttacag ttaccaccat aaccataatg acataaatta gtattaatag
     2161 attaataata ttagttaata tttactagtt cttactcatg ccaggcaata tacataatta
     2221 aaatcaatga acagctaaag ggaaatggtc cccttggtat ttcaattttg tatataagtt
     2281 aactaaagta tagagaaggc cagcagtttt ctgaagatca aagggtctcg aattgactaa
     2341 gttgagatcc aaatcgcaca gctctatttc agagctcacg attttaacag attgttatgt
     2401 tacatgatat tcttatgacc taaatatttc agaagaaatt ggcaaacaaa gcttcataaa
     2461 gaaaatatga cttactggta atttaaccaa actaggcctc tcgcatcata ttctaaaatg
     2521 tagaatttta cagaaacatt atggattagt gtaggtgtat tatgtggatg cttttataat
     2581 attcaactta tcttgttata tattcctaag aattagtatt ttttgttaca tgtattttag
     2641 aaaataggta tgaacaaaat aaaggaatat gcacattgat caagaccaat ccaatgtgga
     2701 tccaggcctg actctggcca tggaagaagt ggggctttgg ttgacaactc ctcaaattaa
     2761 gtaggagcag atcaaaaaca attttaaaaa cagttattta ttacctcatg aaaaatctgc
     2821 tatgttctga attattggaa tagaactcag gcatacacta tagtaaagac tgtattgtgt
     2881 tcattaatgt taagttttaa gttacagatt ctacatgtca tatgtattct gttcgatagg
     2941 aaaaaaatca atatacacta atgacttaaa ctaccaatac tctccgtcac ttaatttctt
     3001 tatatatgcc aagtacagac tgcctatgtt agaaaagtat aaaatattta tattttgctt
     3061 cagaaaacac tttcacgtga agacacgtgt aattgtcagt aaaatttcag agcatacctt
     3121 caaacgagga tgattaaatg accctgtcta catgatgata cactgtataa tcataaaatc
     3181 cctttcatag atataagtaa aaacagtaac aatggtttct ctccatcttg gcaccaatgt
     3241 cacaattatt ggggtttcct gcagatatat gtatctctga tataaaaaaa tttctgtcaa
     3301 gatcccatga tttgaacaca ggtaaagaaa ttaaagtgta attttcacaa aagctagctc
     3361 tacagtaaaa aattacatac tctatcggaa actgtaaaaa cccctgagtt tccagactgg
     3421 ggtaagacga atgctccttg acaaaagttt ggcaatgatt tctgtgagta tgagaccaaa
     3481 atctcataca acagtgaata atgcactaaa cattaaatct acataaacta aaaaggttct
     3541 gtgtaatagt caacaaaatg aaaatgcatc ctagaagatg agagaaagca ttcgtaaacc
     3601 atatatctga caaacatata ataaccaaac atccaaaata cacaagaaag caaactgctc
     3661 tataccagaa gaaacaagag ccaacagcat gattttaaaa tgtgtaagtg tctaaaatga
     3721 acattttttg atagaagata tacaaatggc caacaggtct ataaacaggg tctcaactcc
     3781 aataattgtc taagaaatat atattaaact ccaacattat cacctcacac ttgttaggat
     3841 gagtgctact gaggacaaaa gaggaggact attaaaatga atgtaaactt ataaagccaa
     3901 tgtgaaaaat agtatacaag ttcccaaaga aattacaaac agaacaatca taggctcgac
     3961 tataggtata taaaggaata aaatcaatat gtcaaagagg cctccaagtg caccaggcac
     4021 actcatggta cacaggcata gatgcaggta aaacacccaa acatgtga
//
