LOCUS       NM_001412524            2727 bp    mRNA    linear   ROD 10-APR-2024
DEFINITION  Rattus norvegicus transmembrane serine protease 11B (Tmprss11b),
            mRNA.
ACCESSION   NM_001412524
VERSION     NM_001412524.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2727)
  AUTHORS   Miller,G.S., Zoratti,G.L., Murray,A.S., Bergum,C., Tanabe,L.M. and
            List,K.
  TITLE     HATL5: a cell surface serine protease differentially expressed in
            epithelial cancers
  JOURNAL   PLoS One 9 (2), e87675 (2014)
   PUBMED   24498351
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2727)
  AUTHORS   Gonzalez-Begne,M., Lu,B., Han,X., Hagen,F.K., Hand,A.R.,
            Melvin,J.E. and Yates,J.R.
  TITLE     Proteomic analysis of human parotid gland exosomes by
            multidimensional protein identification technology (MudPIT)
  JOURNAL   J Proteome Res 8 (3), 1304-1314 (2009)
   PUBMED   19199708
REFERENCE   3  (bases 1 to 2727)
  AUTHORS   Puente,X.S. and Lopez-Otin,C.
  TITLE     A genomic analysis of rat proteases and protease inhibitors
  JOURNAL   Genome Res 14 (4), 609-622 (2004)
   PUBMED   15060002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000014.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643294.49746.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760433,
                                           SAMN12840107 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-95                JAXUCZ010000014.1  21738760-21738854
            96-211              JAXUCZ010000014.1  21743197-21743312
            212-330             JAXUCZ010000014.1  21747483-21747601
            331-398             JAXUCZ010000014.1  21747690-21747757
            399-559             JAXUCZ010000014.1  21756388-21756548
            560-598             JAXUCZ010000014.1  21757199-21757237
            599-773             JAXUCZ010000014.1  21757747-21757921
            774-1033            JAXUCZ010000014.1  21758887-21759146
            1034-1176           JAXUCZ010000014.1  21759609-21759751
            1177-2727           JAXUCZ010000014.1  21760557-21762107
FEATURES             Location/Qualifiers
     source          1..2727
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="14"
                     /map="14p21"
     gene            1..2727
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /note="transmembrane serine protease 11B"
                     /db_xref="GeneID:365265"
                     /db_xref="RGD:1303278"
     exon            1..95
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     CDS             88..1338
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /note="airway trypsin-like 5; airway trypsin-like protease
                     5; transmembrane protease, serine 11B"
                     /codon_start=1
                     /product="transmembrane protease serine 11B-like protein"
                     /protein_id="NP_001399453.1"
                     /db_xref="GeneID:365265"
                     /db_xref="RGD:1303278"
                     /translation="MYRPVIASRKSFPPWMIILGVLGVLAILGLIIGLLVHFLAVENK
                     IYYYQGSFKVLNIPYDRNYERETSLESNYLSKILEIKMVDAFESSNIYKQYINSQIIT
                     LVPENNSVTAHIWLVFKDPWSNKENLRRRIESILHQMLENNSGSLTTDPGSLKLTEIT
                     KVDAEKIINNRCGRRPRMSATYDRITGGSTAQKGEWPWQASLRVNGKHHCGASLIGER
                     FLLTAAHCFLRTNNPKNLTVSFGTRVTPAYMQHYVEEVIIHEDYVKGQHHDDVAIIKL
                     TEKVSFRNDVHRVCLPEATQVFPPGEGVVVTGWGSLSYNGKSPLLLQKASIKIIDTNA
                     CNSEEAYGGRIMDTMLCAGYMEGYVDACQGDSGGPLVHPNSRDIWYLVGIVSWGHECG
                     RVNKPGVYMRVTSYRDWIASKTGI"
     exon            96..211
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     exon            212..330
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     exon            331..398
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     exon            399..559
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     exon            560..598
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     exon            599..773
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     exon            774..1033
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     exon            1034..1176
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
     exon            1177..2727
                     /gene="Tmprss11b"
                     /gene_synonym="Hatl5; Tmprss11bnl"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 cacatttacc caagaaccac tatcaacaca taaagagttc agaagttccc tccacattaa
       61 catcagccag cactgtacca gcaagttatg tacagaccag tcatagcatc ccgcaaatct
      121 ttcccaccat ggatgatcat cctcggtgtg cttggagtgc tggccatcct tgggctaatt
      181 attggactct tagttcactt cctggcagta gaaaacaaga tctactacta tcaaggtagt
      241 tttaaagttc tgaatattcc atatgacaga aattatgaaa gagagacatc actagaaagt
      301 aactacctca gtaaaatcct cgagattaaa atggttgatg cctttgagag ttctaacatt
      361 tataaacaat atatcaactc tcagatcatc acattggttc ctgaaaacaa cagcgtgaca
      421 gcacatatat ggctggtgtt taaggacccc tggtcaaaca aggaaaacct aagaagaaga
      481 attgaaagca tcttacatca gatgctggag aacaactcgg gatccttgac tacagatcct
      541 gggtctctga agctcacgga aatcactaaa gttgatgctg agaagattat caacaaccgc
      601 tgcgggagac ggccaagaat gtcggcaacc tatgacagaa tcacgggagg ctccacggct
      661 cagaaaggag aatggccttg gcaagcgagt ctcagggtga atggcaaaca ccactgtgga
      721 gcatctctca ttggcgaaag attcctgcta acagcagcgc attgctttct aaggacaaat
      781 aatccaaaga acttaactgt tagctttggc actagagtaa ctccagccta catgcagcat
      841 tatgttgaag aagttattat ccatgaagat tatgttaagg ggcagcatca tgatgatgtc
      901 gcaattataa agctcactga aaaagtttca ttcaggaatg acgtacatcg ggtttgcctc
      961 ccggaagcca cacaggtttt cccaccaggg gaaggggtcg ttgttacagg atggggatca
     1021 ctttcttaca atggtaaatc cccactgtta cttcagaaag catccattaa aattatcgat
     1081 acaaatgctt gcaattctga agaagcttat ggaggcagga taatggacac aatgctctgc
     1141 gctggttaca tggaaggcta tgtcgatgct tgccagggtg actctggagg acccctagtt
     1201 catcccaatt ctcgagatat ttggtacctt gttgggatag tgagctgggg acatgaatgt
     1261 ggcagagtca acaagccagg ggtctatatg agagtgactt cctaccgtga ctggattgcc
     1321 tccaagactg gtatctagta gaaaaatcat cttctaataa tgagtgcaga tcgtattgcc
     1381 tggtactcta tcatggaaca cccatttctt tatttttttt ccattttatg tgagtttttg
     1441 catatgtgtg ggtaaatgtg tgtttgcgct cacatatgga agtgtgcatg taagtagagg
     1501 cttaagttga tgttaagaat catcctcaat aatttcaatg agacaggatc ttggtcaaac
     1561 caagagctct cagatatata ctgccttaca agtcaggttg ctgttagaac agccagaata
     1621 cagcaaatac agaggtgaat gccagcagca aaccactgaa ctgagaatag gacccccgtt
     1681 gaaggaatca gagaaaggac tgaaagagct tgaaggggct tgagacccca aaagtacaac
     1741 aatgccaagc aaccagagct tccagggact aagccactac ctaaagacta tacatggact
     1801 gaccctggac tctgacccca taggtagcaa tgaatatcct agtaagagca ccagtggaag
     1861 gggaagccct gggtcctgcc aagactgacc ccccagtgaa cgtgattgtt ggggggaggg
     1921 cggtaatggg gggaggatgg ggaggggaac acccatataa aagggaaggg ggggtgaggg
     1981 ggatgttggc ccggaaacgg ggaaggggaa taacaatcaa aatgtaaata agaaatactc
     2041 aagttaataa agatgaaaaa aaaaaagaac tgcctatttc tgtcttctaa ggacagaagt
     2101 acagacaggc ttctatgcct gtcaggtatt tgtgagcatc ctggggctcc catttctagt
     2161 ccttaggttt tcttgcttaa tcactgagca agccctcagc tgactttaaa cattactatt
     2221 ttgtgtatat gggtgttttt ttcctgcccc acatacatgc ctagaggtca gaagaggatg
     2281 ctgaatcctc tgggactgga gttacagaca gtatgagcca ccctatgggt gctgggaatt
     2341 gaacctaggt ctgttggaag aacagctggg cctcttcacc gtagagccat tcccactgat
     2401 tactttacat actttttaaa tgtgtataat ggttattttg aaagaattat agccctaagg
     2461 gaatatttgt aaacttttaa gcaaactaaa caagacaaaa tgagagaccc ctgaatttct
     2521 tggttcagaa aacccttagc caagaaagtg cttccaccaa aatgctggtg aaatactatt
     2581 tgtgtcctac tttatcagcc tacattattg ctatttcagt gcacaaggtt cttggttttt
     2641 atcatataga ttttgtaaaa ctgtggaagc atagcattga ctgtggtgat ttatgagact
     2701 gtctgagggg agaggagtaa ctcccaa
//
