LOCUS       NM_001302749            1392 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Rattus norvegicus transmembrane and immunoglobulin domain
            containing 3 (Tmigd3), mRNA.
ACCESSION   NM_001302749
VERSION     NM_001302749.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1392)
  AUTHORS   Iyer,S.V., Ranjan,A., Elias,H.K., Parrales,A., Sasaki,H., Roy,B.C.,
            Umar,S., Tawfik,O.W. and Iwakuma,T.
  TITLE     Genome-wide RNAi screening identifies TMIGD3 isoform1 as a
            suppressor of NF-kappaB and osteosarcoma progression
  JOURNAL   Nat Commun 7, 13561 (2016)
   PUBMED   27886186
  REMARK    Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000002.1, FM077301.1 and BC097395.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC097395.1, CV115996.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-11                JAXUCZ010000002.1  196027286-196027296
            12-154              FM077301.1         11-153
            155-1392            BC097395.1         1-1238
FEATURES             Location/Qualifiers
     source          1..1392
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..1392
                     /gene="Tmigd3"
                     /note="transmembrane and immunoglobulin domain containing
                     3"
                     /db_xref="GeneID:100363178"
                     /db_xref="RGD:2324712"
     exon            1..203
                     /gene="Tmigd3"
                     /inference="alignment:Splign:2.1.0"
     exon            204..305
                     /gene="Tmigd3"
                     /inference="alignment:Splign:2.1.0"
     CDS             266..964
                     /gene="Tmigd3"
                     /codon_start=1
                     /product="transmembrane and immunoglobulin domain
                     containing 3 precursor"
                     /protein_id="NP_001289678.1"
                     /db_xref="GeneID:100363178"
                     /db_xref="RGD:2324712"
                     /translation="MEPLLLLSLALFSDAMVMDEKVKSGVELDTASAICNYDAHYKDH
                     TKYWCRGYFRDSCNIIAFTPNSSNRVALKDTGDQLIITVSCLVKEDTGWYWCGIQRDF
                     ARDDMDFTKLIVTDNREDRANGLSPGTSGNRTRSCKTSKAVQKAEGSRMSILIVCVLI
                     SGLGIIFLISHMSRGRRSQRNRGVTGKSINRNPQASQAPSMVSIPLTVLPKVPRQNGQ
                     QKALQWTGNATKTG"
     exon            306..647
                     /gene="Tmigd3"
                     /inference="alignment:Splign:2.1.0"
     exon            648..714
                     /gene="Tmigd3"
                     /inference="alignment:Splign:2.1.0"
     exon            715..815
                     /gene="Tmigd3"
                     /inference="alignment:Splign:2.1.0"
     exon            816..883
                     /gene="Tmigd3"
                     /inference="alignment:Splign:2.1.0"
     exon            884..1347
                     /gene="Tmigd3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ttacagtttc acagcatcca aatggcttgg aaaatctgag tgtgtctgag gctctgctct
       61 tacagtcaag gcatgcctgc ctggttctct agagaagggt tggagggatg gaatgtggct
      121 gctgcaagct tccatggcag ttgctaaaga tgaccagatg gacctgcagg acttcagcgg
      181 gacccactga ccaagaaggg cagatccagg gttcctgaga tcctccctcg agttattcca
      241 gctgaaggct cacttccttc tcagcatgga gcccctccta ctgctctcct tggctctctt
      301 ttccgatgcc atggtcatgg atgaaaaggt gaaatcaggc gttgagctgg acacagcttc
      361 tgcaatctgt aactatgacg cccactacaa ggaccacacc aagtactggt gccgtggcta
      421 tttcagggac tcgtgcaaca ttattgcctt cacccctaat agcagcaacc gtgtggccct
      481 gaaagacaca ggagaccaac tcatcatcac tgtctcctgc ctggtcaagg aggacacagg
      541 ctggtactgg tgtggtatcc agcgggactt tgccagagat gacatggatt ttacaaagct
      601 gattgtgact gacaacagag aagaccgggc caatggcctt tcacctggca cttcaggcaa
      661 caggacccgg agctgtaaga cgtccaaagc tgttcaaaag gcagagggct cccgaatgtc
      721 cattctgatc gtttgtgtac tgattagcgg gctggggatc atctttttaa tcagtcatat
      781 gtccagagga agacgaagcc aaagaaacag aggagttact ggcaaaagca tcaatagaaa
      841 cccacaagca agtcaagctc cgtccatggt ctccatcccc ttgactgtcc ttcccaaggt
      901 cccaagacaa aatggtcaac aaaaagccct ccaatggact ggaaatgcca caaagaccgg
      961 ataagtgtat tcctttactt gggtttgaag gaatagggtg tagaactggt cactggggct
     1021 gccgtggaga ttgttcctgc agagaacatg gaaggtatca gttttggggg gatcagtatc
     1081 tctgccctac tcctgccgtc cctctcggat aagaccctga gcacgaccac tacccacggg
     1141 aacttgcaag ccggctacaa ctcttcagag ggaagggcag tgagtctttt cgctggtgct
     1201 gggcaagtga acccaggact gtttgcacac tgggtcaagc cctctaccac tgagctacat
     1261 gctatatctc agtgagacct ttaaaatgag aagtagagct gtacttgaaa gggtatacga
     1321 aataaaggag cagaggtaga gtgggaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
     1381 aaaaaaaaaa aa
//
