LOCUS       NM_001033896            2082 bp    mRNA    linear   ROD 09-FEB-2025
DEFINITION  Rattus norvegicus transmembrane protein 79 (Tmem79), mRNA.
ACCESSION   NM_001033896 XM_227398
VERSION     NM_001033896.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2082)
  AUTHORS   Saunders,S.P., Goh,C.S., Brown,S.J., Palmer,C.N., Porter,R.M.,
            Cole,C., Campbell,L.E., Gierlinski,M., Barton,G.J., Schneider,G.,
            Balmain,A., Prescott,A.R., Weidinger,S., Baurecht,H., Kabesch,M.,
            Gieger,C., Lee,Y.A., Tavendale,R., Mukhopadhyay,S., Turner,S.W.,
            Madhok,V.B., Sullivan,F.M., Relton,C., Burn,J., Meggitt,S.,
            Smith,C.H., Allen,M.A., Barker,J.N., Reynolds,N.J., Cordell,H.J.,
            Irvine,A.D., McLean,W.H., Sandilands,A. and Fallon,P.G.
  TITLE     Tmem79/Matt is the matted mouse gene and is a predisposing gene for
            atopic dermatitis in human subjects
  JOURNAL   J Allergy Clin Immunol 132 (5), 1121-1129 (2013)
   PUBMED   24084074
  REMARK    Erratum:[J Allergy Clin Immunol. 2015 Dec;136(6):1710. doi:
            10.1016/j.jaci.2015.10.002.. PMID: 28843836]
REFERENCE   2  (bases 1 to 2082)
  AUTHORS   Sasaki,T., Shiohama,A., Kubo,A., Kawasaki,H., Ishida-Yamamoto,A.,
            Yamada,T., Hachiya,T., Shimizu,A., Okano,H., Kudoh,J. and Amagai,M.
  TITLE     A homozygous nonsense mutation in the gene for Tmem79, a component
            for the lamellar granule secretory system, produces spontaneous
            eczema in an experimental model of atopic dermatitis
  JOURNAL   J Allergy Clin Immunol 132 (5), 1111-1120 (2013)
   PUBMED   24060273
REFERENCE   3  (bases 1 to 2082)
  AUTHORS   Yu,H., Tardivo,L., Tam,S., Weiner,E., Gebreab,F., Fan,C.,
            Svrzikapa,N., Hirozane-Kishikawa,T., Rietman,E., Yang,X.,
            Sahalie,J., Salehi-Ashtiani,K., Hao,T., Cusick,M.E., Hill,D.E.,
            Roth,F.P., Braun,P. and Vidal,M.
  TITLE     Next-generation sequencing to generate interactome datasets
  JOURNAL   Nat Methods 8 (6), 478-480 (2011)
   PUBMED   21516116
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC101913.1.
            
            On Sep 30, 2005 this sequence version replaced XM_227398.3.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC101913.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00155332, SAMN16676786
                                           [ECO:0000348]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2082
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="2"
                     /map="2q34"
     gene            1..2082
                     /gene="Tmem79"
                     /gene_synonym="RGD1309886"
                     /note="transmembrane protein 79"
                     /db_xref="GeneID:310626"
                     /db_xref="RGD:1309886"
     exon            1..71
                     /gene="Tmem79"
                     /gene_synonym="RGD1309886"
                     /inference="alignment:Splign:2.1.0"
     exon            72..961
                     /gene="Tmem79"
                     /gene_synonym="RGD1309886"
                     /inference="alignment:Splign:2.1.0"
     CDS             214..1389
                     /gene="Tmem79"
                     /gene_synonym="RGD1309886"
                     /note="mattrin"
                     /codon_start=1
                     /product="transmembrane protein 79"
                     /protein_id="NP_001029068.1"
                     /db_xref="GeneID:310626"
                     /db_xref="RGD:1309886"
                     /translation="MTEPETLALLDMKDTEISEKSPPQASVLQPEEEGGTESPGAESL
                     RVGSSVGSPTVREGPEDGPDSTISEAATLPWGTDPHPSAPLPDPPGWRDIGPELLESE
                     APIKSEEPLKEDANLLPEKTVRAFVPIDLQCIERKPQEERIKHREAGPGELRNFLPAR
                     LSHPEPPERKWAEAVVRPPGRSCGGCGSCGGREALRAVASVVAALIFFPCLLYGAYAF
                     LPFDAPRLPTMSSRLVYTLRCGVFATFPIVLGLLVYGLSLLCFSALRPFGEPRREVEI
                     HRQYVAQSVQLFILYFFNLAVLSTYLPQDTLKLLPLLTGLFAISRLIYWLTFAVGRSF
                     RGFGYGLTFLPLLAMLVWNLYYMFVVEPERMLSASESRLDYPDHVRSVSDYRPRSWG"
     exon            962..1175
                     /gene="Tmem79"
                     /gene_synonym="RGD1309886"
                     /inference="alignment:Splign:2.1.0"
     exon            1176..2062
                     /gene="Tmem79"
                     /gene_synonym="RGD1309886"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gaaatacttg cagagccagc cagaagctag gcagttcttt tccggatcct ctgcctctct
       61 gcagatgtaa atcccacgag gccggctgct ctggggagtt ctaggtctga gaaactgtac
      121 tagggccaga agacaaggta ttttcacaga acctccccca ctccctatag gatgacatcg
      181 ccttgtggta gatctcagaa ctgaagcctc ataatgacag aaccggagac actggccctg
      241 ctggacatga aggacactga gatttcagag aagagcccac cgcaggcttc agtcctgcag
      301 ccagaggaag aaggtgggac tgagtcccct ggagctgagt ccctcagagt ggggtcttca
      361 gtagggtctc ctacagtcag agaggggcct gaggatggac cagacagcac aataagtgag
      421 gctgccactt taccttgggg aactgacccc catcccagcg ccccacttcc ggatcccccg
      481 ggctggcgag atattgggcc agagctccta gagtcagaag cacctattaa gtcggaggaa
      541 ccactcaaag aggatgccaa cctgctccct gagaagacag ttagggcctt cgtgcccatt
      601 gacctacagt gcatcgagcg gaagcctcag gaggagcgca tcaagcatcg tgaggccgga
      661 ccaggcgagc tcaggaattt cttgccagcc cgactcagcc accctgagcc cccagagcgc
      721 aagtgggctg aggcagttgt gagaccccct ggccggtcct gcgggggctg tggaagctgt
      781 ggaggccgtg aggcactgag agctgtagcc tcggtggtgg ctgccctcat cttcttcccc
      841 tgcctgctgt atggagcata cgccttcctg cctttcgatg ctccaaggct gcccaccatg
      901 agctcccgct tggtctatac cctccgctgt ggggtctttg ccaccttccc catcgtgctg
      961 gggctcctcg tgtacgggct gagcctattg tgcttttctg cccttcggcc ctttggagag
     1021 ccgagacggg aagtagagat ccaccggcag tacgtggccc agtctgtgca gctcttcatc
     1081 ctctacttct ttaacctggc tgtgctttcc acctatctgc cccaggacac gctcaagctg
     1141 ctccccctgc tcaccggtct gtttgccata tctcggctga tatactggct gacctttgct
     1201 gtgggccgct ccttccgagg ctttggctac ggcctgactt tcctgccgct cttggccatg
     1261 ctggtgtgga acctctatta catgttcgtg gtggagccag agcgcatgct cagtgcctcc
     1321 gagagccgct tggactaccc cgaccatgtc cggtctgttt ctgactacag gccccgctca
     1381 tggggctgag ccacccagag ctgtgcaggg ggttttcggc atttccctgg aacagttgca
     1441 gacctggctt ctgcccagcc aatggacatt tgttgcaagg aaccttgcta cttccccact
     1501 ggggccccat acccctgttt tctcctagct cctgctttac ccgagaggac aagagcccaa
     1561 gggagactgg agaaacacac ttccttcttg ggcagcttcc taccatgacc caggagctat
     1621 ggctggatgg ttatcttact ccctagcttc ttgtgggtca ggagtgcaga accacagccc
     1681 cacctgactg tctgtgccag ccatctagaa gagagtcaag gagaaggaaa aactgcccac
     1741 acccaagggt aaagttgatg tcatatcaga tagttggtga aaacctttct ggaggacctt
     1801 gggttcagga ctcgattacc actggcctca agactctttt gcctcagtca agacatacat
     1861 agttgttgtc ttctctctcc caactacatg ggtctctgtg accttccact tttcagactt
     1921 ccaagaagtc ccactgtagg gggaagggca tagagataaa acctccagaa gaactgtgtt
     1981 tgtactcaca tggtggctag gaaggcaggg tggccgtcag cctgtatgta tatgtgagta
     2041 tgcaataaat cactgccact ctaaaaaaaa aaaaaaaaaa aa
//
