LOCUS       NM_001399333            4685 bp    mRNA    linear   ROD 28-MAR-2024
DEFINITION  Rattus norvegicus transmembrane protein 64 (Tmem64), mRNA.
ACCESSION   NM_001399333 XM_003749909
VERSION     NM_001399333.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 4685)
  AUTHORS   Jeong,B.C., Kim,T.S., Kim,H.S., Lee,S.H. and Choi,Y.
  TITLE     Transmembrane protein 64 reciprocally regulates osteoblast and
            adipocyte differentiation by modulating Wnt/beta-catenin signaling
  JOURNAL   Bone 78, 165-173 (2015)
   PUBMED   25979161
REFERENCE   2  (bases 1 to 4685)
  AUTHORS   Kim,H., Kim,T., Jeong,B.C., Cho,I.T., Han,D., Takegahara,N.,
            Negishi-Koga,T., Takayanagi,H., Lee,J.H., Sul,J.Y., Prasad,V.,
            Lee,S.H. and Choi,Y.
  TITLE     Tmem64 modulates calcium signaling during RANKL-mediated osteoclast
            differentiation
  JOURNAL   Cell Metab 17 (2), 249-260 (2013)
   PUBMED   23395171
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Jan 6, 2022 this sequence version replaced XM_003749909.5.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR22582416.133971.1,
                                           SRR26643429.18925.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760386
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-971               JAXUCZ010000005.1  33496032-33497002
            972-1127            JAXUCZ010000005.1  33510229-33510384
            1128-4685           JAXUCZ010000005.1  33512298-33515855
FEATURES             Location/Qualifiers
     source          1..4685
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q13"
     gene            1..4685
                     /gene="Tmem64"
                     /note="transmembrane protein 64"
                     /db_xref="GeneID:689176"
                     /db_xref="RGD:1596128"
     exon            1..971
                     /gene="Tmem64"
                     /inference="alignment:Splign:2.1.0"
     CDS             180..1319
                     /gene="Tmem64"
                     /codon_start=1
                     /product="transmembrane protein 64"
                     /protein_id="NP_001386262.1"
                     /db_xref="GeneID:689176"
                     /db_xref="RGD:1596128"
                     /translation="MRNPGGSLLHTLPRALQHAGRPGGAEQPGRWAPERTAGGDCSED
                     RLPRGGGASAAAAAAAASGALLGAYLERHGPPAASDLPAPAGALAGGPGSGGGVVVGV
                     AEVRNWRCCCLGSTCWCRSLVLVCVLAALCFASLALVRRYLQHLLLWVESLDSLLGVL
                     LFVVGFIVVSFPCGWGYIVLNVAAGYLYGFVLGMGLMVVGVLIGTFIAHVVCKRLLTA
                     WVAARIQSSDKLSAVIRVVEGGSGLKVVALARLTPIPFGLQNAVFSITDLSLPNYLMA
                     SSVGLLPTQLLNSYLGTTLRTMEDVIAEQSVSGYFVFCLQIVISIGLMFYVVHRAQVE
                     LNAAIVACEMELKTSLVKGSQPNPSGSSFYNKRTLTFSGGGINVV"
     exon            972..1127
                     /gene="Tmem64"
                     /inference="alignment:Splign:2.1.0"
     exon            1128..4685
                     /gene="Tmem64"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agactccacc gactcccggt cggaccgtgt ctcgactgcc gctgctgccg tctgtctccg
       61 gccgttccct ccccgcaagc ggacgcaggg agccgaggcc tggcgtgcgg ggtgccatgg
      121 aaggcggcag gcagggggac gcggcgggag cggagacact ggccggctga ggccgaggca
      181 tgcggaaccc cggcggaagc ctgctccaca cgctgccccg ggccttgcag cacgccggtc
      241 ggccgggcgg tgcggagcag ccgggccgct gggcaccgga gcggacagcg ggaggggact
      301 gctcggagga ccgccttccc cgtgggggcg gggccagcgc ggctgctgct gcggcggcgg
      361 cctcgggcgc gctgctcggc gcctatctgg agcgccacgg tccgcccgcg gcctcggact
      421 tgccggcgcc ggccggggcg ttggcaggcg gccccgggag cggcggcggc gtggtggtcg
      481 gggtggccga ggtgagaaac tggcgctgct gctgcctcgg cagcacctgt tggtgccgga
      541 gcctcgtgct ggtgtgcgtg ctggccgccc tgtgcttcgc ttccctggcc ctggtccgcc
      601 gctacctgca gcacctcctg ctctgggtgg agagcctcga ctcgctgctc ggtgtcctgc
      661 tcttcgtcgt gggcttcatc gtggtctcct tcccctgcgg ctggggctac atcgtgctta
      721 atgtggcggc cggctacctg tacggcttcg tgctaggcat ggggctcatg gtggtgggcg
      781 tcctcatcgg cacctttatt gctcatgtgg tctgcaagcg gctgctcacc gcctgggtgg
      841 ccgccaggat ccagagcagc gacaagctga gcgccgttat ccgtgtcgtg gagggaggaa
      901 gcggcctgaa ggtggtggcg ctggcccggc tgactcccat accttttggg cttcagaatg
      961 cagtgttttc gattactgat ctttccttac ccaactatct gatggcgtct tcagttggac
     1021 tgcttccgac ccagcttctg aattcttact tgggaaccac actacggacg atggaagatg
     1081 tcattgcaga acaaagtgtt agtggatatt ttgtcttttg tttacagatt gttatcagca
     1141 taggcctcat gttttatgta gttcatcgcg ctcaagtgga attgaatgca gctatcgtcg
     1201 cttgtgagat ggaactgaaa acctctctgg ttaaaggcag tcaaccgaat cccagtggct
     1261 cttccttcta caacaagagg accctcacgt tttctggagg tggaatcaat gttgtatgac
     1321 tcttacaaac tgtgattgtc gagcgcctac tctgctgtcc gggcctagca gtcacttacc
     1381 taatggcaga gacaagtgcc gttgtattat ggcacaagca aaactgacta gtttttaaat
     1441 tgcacaattt tctaaaagca agaatcattt tctgggtctg taaatgtaga tgcagctttg
     1501 gctgcccctt gtcatacctg taatggccta taggtgtgca ctttagtgtt tttgaattat
     1561 tttattgctg ggacttatga acagagaaat aacccaaatt tttttttctg tttagtatct
     1621 ttatttataa agcccatgaa tagttgtgtg catctgtctt taaagatgag taaaaatgta
     1681 cagttctcag tggctcactg ttggatgttc tttgctttgg cattctgtcc agaagggtaa
     1741 actgttttgt ttattgttca cttgtttgtt tcaagcagga aaacttcgct ttacttttct
     1801 tgcttgtaag agaatagatg tactttggtc gaatgtatgt cagcattatg tcactgtggg
     1861 ccatttacaa ctttgcgtac aagcgtaaat cctacattgt gggactgaag tgctcttaag
     1921 acccctttta ttttcactgt gtaatatgca aagtgaaagg gacattattt agcaggcgac
     1981 tcacaagtcg agcctgcatt cttatttgat tatcctgttt tcacccttta ggcctcatcc
     2041 aagggctgtc cgaaagcact cttaccaaac catttctccc ttttatatta ataattaggc
     2101 tttgaaatta acatattatt cctataaaac ggtgggctta ccatttctga cgttgtcatt
     2161 caggtggcct tgtttagtca aaacgccttg ttaaaaagaa acaagcttta aaatcacgtt
     2221 tatagtttca gtaaagtact tataatatat atgtctctat agttttcagc tttaaaacta
     2281 taaacaaaca ttaataaaag cccatgtttg tgctatctgc tgtattattg ctgttttgtt
     2341 tggggctttg ataattcctt ttccctgatg agactcagga attctgaaat gtgaaatcgt
     2401 cttggttctt tttctcggag catgtgtgtt tgctaacagc acataggact tagcatacag
     2461 taatctgaca tgattcacac agcgaacact cattgatcag ctttactttt gaagtagtta
     2521 attgcaaact taatgaatag ttgattttgt tggttacaaa tgagactgta gtaatacggt
     2581 aacgttttct gttaagtact tggcttttct atgactgttc caacctgtca gaagtctctc
     2641 cgctgccttt tcctggcggt aaaaccattg ccctggtagc tgctgacata gagtaatcct
     2701 gtgcaagcag atttttctag cttaacacca gagatgactt tgattgtgtt cacatacaag
     2761 gtttttgccc agttcaggtt gttttccttc cctccctgat acgtaaattc cttcgcctct
     2821 gagtagcagt agaagaccag agtaactatg acaaaggcac ctggtctaca gcgcatgcct
     2881 ggcctccaga cctttgttat cagtagagaa acaactatgt atactttgag tcctcactgc
     2941 ctgtttagtt ttatttagtt taaccatccc aataaaggaa atatttgatt tgttcttgtt
     3001 tttagtctga ctttgcaaac tttttcttgt gtttcttatc agctgctttt tgttaaggac
     3061 tatttaagat cacggttttc atgcttgttt tacagttggt gtattttgaa gtgcattata
     3121 tttacttagc atttgtaact tgaacgactt caccaaatga gtaccttttg gtaatttgta
     3181 ataacttctt ccaaatgtta acactttccc tggtaattgt attacatatg tgaagagaaa
     3241 agaaataatt ttctgtattc tgccaatcat aattttatat aataaatcat caacttttat
     3301 agtagtatgg attgacaatt tctaaagttc taatgtagct gtgcttttcc ctcctttagc
     3361 atttccaagg taccagtaaa cagcccttca tgattgccaa gttatttgat cggtgcgtcc
     3421 ggtggctggt ggctgagtta tatttatact cactgtaatc tgtacaacat agccctgtca
     3481 tggtcactgg ctctaaccct gtaccttgag cttacacagc aggagttgcc aggcagtgct
     3541 ctgggcacac gttgcctcca gcagtgttta ggcagtgctt gttcatggaa gtgaaacgtg
     3601 gtgtccttac attggtaaac tacagtctga tgttgcttta tgttccttta gagtccacct
     3661 agttttcact ctggttaacg ctgtgttctg tcttccctaa gattgcctct tggacaaagt
     3721 tgtattacct ctttttaaaa ccatgtttat atttactgtg ctttaatgtc acttttattt
     3781 catcatctga tctgtgaaaa atggaaatct gtactcttgg tgaaaatcat gctatcgagt
     3841 cactgttgcc agaatgttca ctctcagttt atattcagag tcagccatac tcacccttga
     3901 tgcactgtaa ctggctgcta atgttccacg gtggctttcc ccaacgctca tgcaatttcc
     3961 tctcggaaaa ctattgaatc cattgtttat ttgccctcac tgtaaacaaa ctaaacggtt
     4021 gagacacacg cacgtcccca gcaccagacc tgttaacccg tggtggtgat ttggactctt
     4081 actggggaag ttactgtgac ttaaatttga tgtccgtgag actgaacttt ccagttcttg
     4141 aaagctgcta gtctgtgcca cattggtaca atagatcctt cctgtgtggc agatggatgc
     4201 catttacagg aaaggagcat cgaagagaaa aaagtttatt gggaaaccag acaacagctg
     4261 taactgggtt gatggccttg gagctgagat agtgttgccg ctgaaggcta ctcccaggct
     4321 tggaatggtc caggtaatag ttattgtctg gatcctcaga tgtttctggt ttctcttata
     4381 ataaggtatt taggatatat atttttaaag ttcattgctt taggctgaaa agccatttaa
     4441 acggggtgag gagttacttt cttaggacat ttaaaactca ggagttcaaa taaactcaca
     4501 aattgaacag acactgttga ctttgcgacc tggtacatct gaactgcaca gtgattgcta
     4561 cagactgttc tcaaaggtga ctgggatcta cagtagcaga ttctaacagc aaaacagtta
     4621 caatgtcttg aaagttggta tcccaaatca ctcgtgtgcc taagaaaata aaaggaaata
     4681 tttta
//
