LOCUS       NM_001271055            1485 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus transmembrane protein 59-like (Tmem59l), mRNA.
ACCESSION   NM_001271055 XM_224729
VERSION     NM_001271055.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1485)
  AUTHORS   Zheng,Q., Zheng,X., Zhang,L., Luo,H., Qian,L., Fu,X., Liu,Y.,
            Gao,Y., Niu,M., Meng,J., Zhang,M., Bu,G., Xu,H. and Zhang,Y.W.
  TITLE     The Neuron-Specific Protein TMEM59L Mediates Oxidative
            Stress-Induced Cell Death
  JOURNAL   Mol Neurobiol 54 (6), 4189-4200 (2017)
   PUBMED   27324899
  REMARK    GeneRIF: TMEM59L is a pro-apoptotic neuronal protein involved in
            animal behaviors such as anxiety, depression, and memory.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Aug 29, 2012 this sequence version replaced XM_224729.6.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: FQ214027.1, FQ212329.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-206               JAXUCZ010000016.1  18975631-18975836
            207-351             JAXUCZ010000016.1  18976700-18976844
            352-449             JAXUCZ010000016.1  18976933-18977030
            450-602             JAXUCZ010000016.1  18977243-18977395
            603-705             JAXUCZ010000016.1  18978062-18978164
            706-820             JAXUCZ010000016.1  18978382-18978496
            821-938             JAXUCZ010000016.1  18978572-18978689
            939-1485            JAXUCZ010000016.1  18978808-18979354
FEATURES             Location/Qualifiers
     source          1..1485
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..1485
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /note="transmembrane protein 59-like"
                     /db_xref="GeneID:306349"
                     /db_xref="RGD:1305557"
     exon            1..206
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /inference="alignment:Splign:2.1.0"
     CDS             57..1067
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /note="brain-specific membrane-anchored protein"
                     /codon_start=1
                     /product="transmembrane protein 59-like precursor"
                     /protein_id="NP_001257984.1"
                     /db_xref="GeneID:306349"
                     /db_xref="RGD:1305557"
                     /translation="MAAVALPLLLLLASPATPTPARDPFSPQLGDTQRCQQRCRQRHP
                     GLPPAQPEPEGPSESPNNKAVLINACERGCRLFSICRFVARSSRPNATETECEAACTE
                     AYVKAKEQQACSEGCWGQIPEPETQLEQKELALDPPSGSLSLRHLFTMLCSDLMSSAQ
                     DLISSTWTYSLQTDNRKVVVFQTQPVVENFAFQGSRLQRVEVTWRGSHPKALEVHMDP
                     MSPLEKVRRAKPHLKTSKAKVESEDQQESDFLSCMSRRSGLPRWVLFCCLFLSVLIIL
                     WLSCCTLVTTPGQHLKFQPLTAEQHKGLLVESNWPLYPPLPPAYEDSPPPYKLKLDLT
                     TL"
     exon            207..351
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /inference="alignment:Splign:2.1.0"
     exon            352..449
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /inference="alignment:Splign:2.1.0"
     exon            450..602
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /inference="alignment:Splign:2.1.0"
     exon            603..705
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /inference="alignment:Splign:2.1.0"
     exon            706..820
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /inference="alignment:Splign:2.1.0"
     exon            821..938
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1485
                     /gene="Tmem59l"
                     /gene_synonym="C19orf4; RGD1305557"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 acccggtccc gcagcctgac acccgcaccc ggatcccgcg ctgcgcacgc tcagccatgg
       61 ctgcggtagc gttgccgctg ttgttgttgt tggcgtcacc ggccacccca accccagcgc
      121 gcgacccctt ctctccgcag ctcggggaca ctcagaggtg ccagcagcgg tgtcggcagc
      181 gtcaccctgg cttgccccct gcgcagcctg agccagaggg cccctctgag tccccgaata
      241 acaaggccgt cctgatcaac gcttgtgagc ggggctgtcg gcttttctcc atctgccgct
      301 tcgtggccag gagctctagg cccaatgcca cagagacaga atgtgaagca gcctgcaccg
      361 aggcttacgt gaaggcaaag gagcagcagg cctgcagtga agggtgttgg ggccagatcc
      421 ctgaacctga gacccagctg gagcagaagg aattggcttt ggacccacct agtgggagcc
      481 tctccctgcg gcacctgttc accatgctct gcagtgacct tatgagttct gcccaagatt
      541 taatatcctc cacctggaca tactcccttc agacagacaa ccggaaggtg gtggtgttcc
      601 agacccagcc tgtggttgag aactttgcat tccaagggag ccgtctgcag cgggtggagg
      661 tgacctggag ggggtcccac cccaaggccc tagaggtgca catggaccct atgagcccct
      721 tggagaaagt gaggagggcg aagccccacc tgaagaccag caaagccaag gtggagtctg
      781 aggaccaaca ggagagtgac ttcctcagtt gcatgtccag gcgttccggg ctacctcgat
      841 gggtcctgtt ctgttgcctc ttcctctccg tcctgatcat cctgtggctg agttgctgca
      901 ctctggtcac cacaccaggc cagcacctca agttccagcc tctaactgca gaacagcaca
      961 aaggcctcct ggtggagtca aactggccct tgtacccacc cctgccacct gcttatgagg
     1021 acagcccccc gccttacaag ttgaagcttg atttgaccac gctgtaatct cgcctttttc
     1081 caagtacaag ggcctcgcca cattcactta ctctgtaccc taaagtccaa ggtcagggtg
     1141 gagtcttacc tccctctctt gctagcacat ccctcggttc ccttgagaca aacgaaccta
     1201 agtggcaggg agaaggggat ctggcctccc cgccccgtct tgctttccca gggctggttc
     1261 acatgttcta actatggaac ttcatccatg ttgctttctt tttcttcctc tgtgtcctca
     1321 ctgtgggcct gaggtcttag gggttcccct ctgctaaggt tctttctctt tatctctgga
     1381 aacccaaggc agatggtggg aactccatcc caagaagggg ataaggagac atgaaccttt
     1441 aaataaagtg aataaagata ggttggccga gcctgcttca gtctg
//
