LOCUS       NM_001350002            1581 bp    mRNA    linear   ROD 30-MAR-2024
DEFINITION  Rattus norvegicus transmembrane protein 45A (Tmem45a), mRNA.
ACCESSION   NM_001350002 XM_003751037
VERSION     NM_001350002.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1581)
  AUTHORS   Lan,J.Z., Pan,Q., Tao,Q., Shi,X., Wang,W.Z., Xu,B.W. and Luo,J.W.
  TITLE     TMEM45A is involved in renal fibrosis in rats by regulating
            Jagged1/Notch pathway
  JOURNAL   Front Biosci (Landmark Ed) 25 (4), 593-605 (2020)
   PUBMED   31585906
  REMARK    GeneRIF: TMEM45A is involved in renal fibrosis in rats by
            regulating Jagged1/Notch pathway.
            Publication Status: Online-Only
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000011.1, FM117101.1 and FN804690.1.
            
            On Mar 31, 2017 this sequence version replaced XM_003751037.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643429.40938.1,
                                           SRR22582416.1728180.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMEA5760383, SAMEA5760389
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-341               JAXUCZ010000011.1  57182888-57183228
            342-492             JAXUCZ010000011.1  57253333-57253483
            493-1092            FM117101.1         1-600
            1093-1266           FN804690.1         543-716
            1267-1581           JAXUCZ010000011.1  57268316-57268630
FEATURES             Location/Qualifiers
     source          1..1581
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="11"
                     /map="11q12"
     gene            1..1581
                     /gene="Tmem45a"
                     /gene_synonym="Tmem45al"
                     /note="transmembrane protein 45A"
                     /db_xref="GeneID:100911041"
                     /db_xref="RGD:6495353"
     exon            1..341
                     /gene="Tmem45a"
                     /gene_synonym="Tmem45al"
                     /inference="alignment:Splign:2.1.0"
     exon            342..534
                     /gene="Tmem45a"
                     /gene_synonym="Tmem45al"
                     /inference="alignment:Splign:2.1.0"
     CDS             345..1166
                     /gene="Tmem45a"
                     /gene_synonym="Tmem45al"
                     /note="transmembrane protein 45A-like"
                     /codon_start=1
                     /product="transmembrane protein 45A"
                     /protein_id="NP_001336931.1"
                     /db_xref="GeneID:100911041"
                     /db_xref="RGD:6495353"
                     /translation="MGSFIGHALPGTFFIMMGFWWTTKNILKSVYKKHTRTCYLNSKT
                     LLRRIEIWEGVVVVIMALTGIAGEQFISGGPALILYKDGQWNQILGWHHTTMYFFFGL
                     QGVTQIVCFTTNALPLSLSKLMLANAIFVETFIFYNHTHGREMVDIFVHQLLSYTTTA
                     AGLVAFMEFLTKNNVLLELVRSSLILLQGTWFWQVAFVLYPPKGRATWNLSDIGNKMF
                     LSMCFCWHYASIVMLIGVIFALANWLVKSRLRKVCTSEVGLLKHVDREQESEEEV"
     exon            535..741
                     /gene="Tmem45a"
                     /gene_synonym="Tmem45al"
                     /inference="alignment:Splign:2.1.0"
     exon            742..926
                     /gene="Tmem45a"
                     /gene_synonym="Tmem45al"
                     /inference="alignment:Splign:2.1.0"
     exon            927..1072
                     /gene="Tmem45a"
                     /gene_synonym="Tmem45al"
                     /inference="alignment:Splign:2.1.0"
     exon            1073..1581
                     /gene="Tmem45a"
                     /gene_synonym="Tmem45al"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gccccgccgg gaaaccagat gaagcacatc tggacagctg tgccgagaaa gtttgtgggc
       61 cctttccagg cctgccacca gcaaggcacg tcccccacgt agcctcctgc tagccactta
      121 ctacttaaat attttttttt cccaagaagc aatcagcaac ccaagcttga atccttttct
      181 tctcccctat ttgaggcgag gccacatcac atcaacacag tttaattttc atggggcttt
      241 gcgatcaaaa gaacagaaac ggcaacaaaa gtccagctgc cttctgatcc taactgacaa
      301 agtggggacc cagtaaggtg tgagtaaaca ggccaagctg ggtcatgggg agtttcatag
      361 gtcatgctct ccctgggact ttcttcatca tgatgggctt ttggtggact acaaagaaca
      421 ttctgaaatc tgtctacaaa aaacacactc gaacctgcta tctgaattct aaaacattat
      481 tacgtcgaat agagatttgg gaaggagttg ttgtggttat aatggctctt actggtatag
      541 ctggggaaca gtttatctcg ggaggacctg ccttgatctt gtataaagac ggccaatgga
      601 accagatcct gggctggcat cacaccacca tgtacttctt ctttggtcta cagggtgtaa
      661 cccagatcgt atgttttact actaatgcac ttccgctttc cttaagcaag ttgatgttag
      721 cgaatgccat ctttgtggag acatttatct tctacaacca cacacatggt cgggaaatgg
      781 ttgatatttt tgtacaccaa cttctgtcct acaccaccac ggcggcgggt ctagttgcct
      841 tcatggagtt cctcacaaag aacaatgtac ttctggagct cgtgaggtca agtctcatcc
      901 tattacaagg aacctggttc tggcaggttg cttttgttct gtaccctcct aaaggaagag
      961 ctacatggaa cctgtccgat attggaaata aaatgtttct ctcaatgtgc ttttgttggc
     1021 attatgcatc aattgtcatg ctcatcggag taatatttgc gttggccaac tggttagtta
     1081 aatctagact taggaaggtc tgcacctcag aagttggact ccttaaacat gttgaccgtg
     1141 aacaagaatc agaagaagaa gtatgatttt gatgggcatc aagtctttct agataaacct
     1201 tctcattttg ggttgcctgt ttcttttgac tcgagaacag ttctctgagg ctgactccat
     1261 gctgtttgta tttccagttt tgttaaagtg ttggacttta aatatcttac tttcagctct
     1321 gaaagtactg tgggtgataa attcattttg catattgtgc atgcatataa ttcaagagca
     1381 accataattt tttccaaagt catatattgt tccatgttca tttattaaaa ttacatattt
     1441 tatttttcct gatagatacc ttcaagcctt gtggtcttgc catcagtata atacattaaa
     1501 tgttcaattc tacttgttta tcttgttgcc acaatgaaaa aaaataaatg aattcatgca
     1561 ccttggtaca gaaacctcaa a
//
