LOCUS       NM_001100175            2337 bp    mRNA    linear   ROD 27-MAR-2024
DEFINITION  Rattus norvegicus transmembrane protein 38a (Tmem38a), mRNA.
ACCESSION   NM_001100175 XM_001063213 XM_224706
VERSION     NM_001100175.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2337)
  AUTHORS   Gonzales,P.A., Pisitkun,T., Hoffert,J.D., Tchapyjnikov,D.,
            Star,R.A., Kleta,R., Wang,N.S. and Knepper,M.A.
  TITLE     Large-scale proteomics and phosphoproteomics of urinary exosomes
  JOURNAL   J Am Soc Nephrol 20 (2), 363-379 (2009)
   PUBMED   19056867
REFERENCE   2  (bases 1 to 2337)
  AUTHORS   Bleunven,C., Treves,S., Jinyu,X., Leo,E., Ronjat,M., De Waard,M.,
            Kern,G., Flucher,B.E. and Zorzato,F.
  TITLE     SRP-27 is a novel component of the supramolecular signalling
            complex involved in skeletal muscle excitation-contraction coupling
  JOURNAL   Biochem J 411 (2), 343-349 (2008)
   PUBMED   18035970
  REMARK    GeneRIF: SRP-27 is part of a sarcoplasmic reticulum supramolecular
            complex
REFERENCE   3  (bases 1 to 2337)
  AUTHORS   Yazawa,M., Ferrante,C., Feng,J., Mio,K., Ogura,T., Zhang,M.,
            Lin,P.H., Pan,Z., Komazaki,S., Kato,K., Nishi,M., Zhao,X.,
            Weisleder,N., Sato,C., Ma,J. and Takeshima,H.
  TITLE     TRIC channels are essential for Ca2+ handling in intracellular
            stores
  JOURNAL   Nature 448 (7149), 78-82 (2007)
   PUBMED   17611541
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000016.1.
            
            On Dec 7, 2020 this sequence version replaced NM_001100175.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: EF690436.1, SRR26360172.1906885.1
                                           [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-399               JAXUCZ010000016.1  17307306-17307704   c
            400-556             JAXUCZ010000016.1  17299235-17299391   c
            557-741             JAXUCZ010000016.1  17298786-17298970   c
            742-829             JAXUCZ010000016.1  17297638-17297725   c
            830-947             JAXUCZ010000016.1  17294727-17294844   c
            948-2337            JAXUCZ010000016.1  17292215-17293604   c
FEATURES             Location/Qualifiers
     source          1..2337
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="16"
                     /map="16p14"
     gene            1..2337
                     /gene="Tmem38a"
                     /gene_synonym="RGD1307901; Srp-27"
                     /note="transmembrane protein 38a"
                     /db_xref="GeneID:306327"
                     /db_xref="RGD:1307901"
     exon            1..399
                     /gene="Tmem38a"
                     /gene_synonym="RGD1307901; Srp-27"
                     /inference="alignment:Splign:2.1.0"
     CDS             276..1172
                     /gene="Tmem38a"
                     /gene_synonym="RGD1307901; Srp-27"
                     /note="27 kDa sarcoplasmic reticulum protein; TRICA;
                     SPR-27; TRIC-A"
                     /codon_start=1
                     /product="trimeric intracellular cation channel type A"
                     /protein_id="NP_001093645.2"
                     /db_xref="GeneID:306327"
                     /db_xref="RGD:1307901"
                     /translation="MDLISSLSLGELALSFSRVPLFPVFDLSYFIVSIIYLKYEPGSV
                     ELSRRHPVASWLCAMLHCFGSYILADLLLGEPIIDYFSNSSSILLASGVWYLIFFCPL
                     DLFYKCVCFLPVKLIFVAMKEVVRVRKIAVGIHHAHHHYHHGWFIMIATGWVKGSGVA
                     LLSNLEQLLRGVWKPETNEILHMSFPTKASLYGAILFTLQQTRWLPVSKASLIFVFTM
                     FMVSCKVFLTATHSHSSPFDVLEGYICPVLFGATWGGDHHHDNHGAPHGMGLGTQHSG
                     LPAKAKEELSEGFRKKKTKKAD"
     exon            400..556
                     /gene="Tmem38a"
                     /gene_synonym="RGD1307901; Srp-27"
                     /inference="alignment:Splign:2.1.0"
     exon            557..741
                     /gene="Tmem38a"
                     /gene_synonym="RGD1307901; Srp-27"
                     /inference="alignment:Splign:2.1.0"
     exon            742..829
                     /gene="Tmem38a"
                     /gene_synonym="RGD1307901; Srp-27"
                     /inference="alignment:Splign:2.1.0"
     exon            830..947
                     /gene="Tmem38a"
                     /gene_synonym="RGD1307901; Srp-27"
                     /inference="alignment:Splign:2.1.0"
     exon            948..2337
                     /gene="Tmem38a"
                     /gene_synonym="RGD1307901; Srp-27"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agggacacgg ttctaagtag atgtacaaag acaaggttcc ctctgtgtgc gctggatgca
       61 ggggatagat cccttttggc tcagttgacc gggttctagc gtccctgcag cccggtgcct
      121 tgggctccag ggtgctaggc gtccccaccg cccctcctct cctggagggc ggcagggggc
      181 ggtgcctggc agtgagctag gttcattggc gagggagcag tcgccgggca gcggggcgcg
      241 ggacacacgg ggccgcggag gcgccctcca tcgccatgga cctgatatca tcgctgagcc
      301 tgggcgagct agcgctcagc ttctcgcggg tgccgctctt ccctgtcttc gacctcagct
      361 acttcatcgt ctccatcatc tacctgaagt atgagccagg gtctgtggag ctgtcccggc
      421 gtcacccggt ggcatcctgg ctgtgcgcca tgctgcactg ttttgggagt tacatcctgg
      481 ccgacctgct tcttggggag cccatcattg actacttcag caacagctcc agtatcctgc
      541 tggcctccgg agtgtggtac ttgattttct tctgtccctt ggacctcttc tacaagtgcg
      601 tctgctttct gcctgtaaaa ctcatctttg tggctatgaa ggaggtggtg agggtccgaa
      661 agattgctgt gggtatccat cacgcacacc accactacca ccatgggtgg ttcatcatga
      721 tcgccaccgg atgggtcaaa ggctctggcg ttgcccttct gtccaacttg gaacagctgc
      781 ttcgaggcgt ctggaagcca gagaccaatg agatcctaca catgtccttc cccactaagg
      841 ccagtctgta tggagccatc ctgttcacct tgcaacagac ccgctggctc ccagtgtcca
      901 aggccagcct catcttcgtc ttcaccatgt ttatggtgtc gtgtaaggtg ttcctgacag
      961 ccactcactc ccatagttct ccatttgatg tcctggaggg ttacatctgc ccagtgctgt
     1021 ttggggcaac ttggggaggc gaccatcacc atgacaacca tggagcacca catggcatgg
     1081 ggctaggcac ccagcactct ggcttgcctg ctaaggccaa ggaagagctg agcgaaggct
     1141 tcaggaagaa gaagaccaag aaagcggatt agggttggcc ccagggatcg atccactggg
     1201 tgcttgggag aaggatatga actcagagaa actcagaact tagggcattc agggctcgga
     1261 aacccccctc cccccaccag cctcaacttc cccatctaca atttggagcc atcagcaacc
     1321 ccagggctga tgtggggtta aattaatgtg gaggagtttg gtaggagtgg aaaaccctgc
     1381 cttctgccag actcctcatc cggtcacagg ctttggggga tacacagtcc aggcctaaag
     1441 gctggtaggt tcttggtttt cattctgtgt tctaattata tcttgaaacc aaaacaattt
     1501 aaagtcacgt ggagactcaa ttatccaagt tcctcctggg agccaggagc tggggtcctg
     1561 cgtcctttcc caccctccct agaattttat gactcttgct gggcattcag gcaaatggcc
     1621 tcccttctct gagccttctg tttccattct gtagcaccaa gcccccaggt cctcctgtcc
     1681 gcaggaggtc tttacaatgt caaacagttt aacagtgcta ataaggagac tggagctggc
     1741 atgaagggca gtggcagact gctttgtatg tcaggccatt tgtgttggaa cccaggtcac
     1801 ctcactagat actcagctga gtagacacat ctagggctgt ctgttaacgg gtgttgggag
     1861 tggggtgtgt tgttgagttc ccagctgccc acaggcaaaa gaagtgtgtg tgccgggcag
     1921 agggtccaag agccaatagc cttgagtgct cacaattggg ccctgggtgt atcaggtgtc
     1981 cctcgtgtct gatcagcata gttcactcag tcattcaaca aacacacaga tccacacatg
     2041 ctccctgtac agtgttgtgc ggcttggagg aggagcgagc cttgtacagg gcaagggcca
     2101 tggtcaccaa agtctccagg acctctgaga gaggtgagca tggggtactg ctggtctcag
     2161 gcttctgtga ggctcagatc tagttggagt acccagtgtt gcccatttgt tgagaaaacg
     2221 ctcctcacaa cttttcctgg aggtaggtcc tgaggctgga agctcctggg tttcatcccc
     2281 ttggtgtcaa tcaaagctct gtgtgagtga tcagccaata aatctggtgc gagtgaa
//
