LOCUS       NM_001100886            2100 bp    mRNA    linear   ROD 22-MAR-2023
DEFINITION  Rattus norvegicus transmembrane protein 259 (Tmem259), mRNA.
ACCESSION   NM_001100886 XM_001076923 XM_216835
VERSION     NM_001100886.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2100)
  AUTHORS   Yang B, Qu M, Wang R, Chatterton JE, Liu XB, Zhu B, Narisawa S,
            Millan JL, Nakanishi N, Swoboda K, Lipton SA and Zhang D.
  TITLE     The critical role of membralin in postnatal motor neuron survival
            and disease
  JOURNAL   Elife 4, e06500 (2015)
   PUBMED   25977983
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2100)
  AUTHORS   Andersson O and von Euler G.
  TITLE     Characterization and expression of the gene encoding membralin, an
            evolutionary conserved protein expressed in the central nervous
            system
  JOURNAL   Brain Res Gene Expr Patterns 1 (3-4), 205-212 (2002)
   PUBMED   12638133
  REMARK    GeneRIF: genomic organization and expression (membralin)
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CK843921.1 and BC100259.1.
            
            On or before Nov 23, 2008 this sequence version replaced
            XM_216835.4, XM_001076923.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC100259.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMD00132261, SAMD00132262
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-573               CK843921.1         1-573
            574-2100            BC100259.1         519-2045
FEATURES             Location/Qualifiers
     source          1..2100
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /strain="Sprague-Dawley"
                     /db_xref="taxon:10116"
                     /chromosome="7"
                     /map="7q11"
     gene            1..2100
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /note="transmembrane protein 259"
                     /db_xref="GeneID:299608"
                     /db_xref="RGD:1311136"
     exon            1..250
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..1753
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /codon_start=1
                     /product="membralin"
                     /protein_id="NP_001094356.1"
                     /db_xref="GeneID:299608"
                     /db_xref="RGD:1311136"
                     /translation="MSEHAAAPGPGPNGGGGGGAAPVRGPRGPNLNPNPLINVRDRLF
                     HALFFKMAVTYSRLFPPAFRRLFEFFVLLKALFVLFVLAYIHIVFSRSPINCLEHVRD
                     RWPREGVLRVEVRHNSSRAPVILQFCDGGLGGLDLEPGGLELEEEELSVEMFTNSSIK
                     FELDIEPKVFKPPGGADALNDSQDFPFPETPAKAWPQDEYIVEYSLEYGFLRLSQATR
                     QRLSIPVMVVTLDPTREQCFGDRFSRLLLDEFLGYDDVLMSSVKGLAENEENKGFLRN
                     VVSGEHYRFVSMWMARTSYLAAFVIMVIFTLSVSMLLRYSHHQIFVFIVDLLQMLEMN
                     MAIAFPAAPLLTVILALVGMEAIMSEFFNDTTTAFYIILIVWLADQYDAICCHTNTSK
                     RHWLRFFYLYHFAFYAYHYRFNGQYSSLALVTSWLFIQHSMIYFFHHYELPAILQQIR
                     IQEMLLQTPPLGPGTPTALPDDLNNNSGSPATPDPSPPLALGPSSSPAPTGGASGPGS
                     LGAGASVSGSDLGWVAETAAIISDASFLSGLSASLLERRPAAPSAPDSARPDPGASLE
                     DAPAPAGS"
     exon            251..508
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            509..608
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            609..719
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            720..842
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            843..943
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            944..1001
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            1002..1085
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            1086..1218
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            1219..1318
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
     exon            1319..2052
                     /gene="Tmem259"
                     /gene_synonym="Mbrl; RGD1311136"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gcggccgccg gggtgacgcg gggcggtgat gtcggagcac gcggcagccc cagggcccgg
       61 gcccaacggc ggcgggggtg gcggcgcggc gcccgtgcgc ggcccgcgcg gccccaatct
      121 caaccccaac ccgctcatca acgtgcgcga ccggctcttc cacgcgctct tcttcaagat
      181 ggccgtcacc tactcacgcc tcttcccacc tgctttccgc cgcctctttg agttcttcgt
      241 tctgctcaag gccctgtttg tgcttttcgt cctcgcctac atacacatcg tcttctcccg
      301 gtcccccatc aactgcttgg agcatgttcg agaccgatgg ccacgggagg gtgtcctgcg
      361 ggtggaggtg cgccacaact ccagccgggc accggtgatc ctgcagttct gtgatggggg
      421 cctcggtggc ctagacctgg agcccggggg cctggagctg gaggaggagg agctttccgt
      481 ggagatgttc accaacagct ccatcaagtt tgagctggac attgagccca aggtgttcaa
      541 gccaccaggg ggcgccgatg ccctgaatga cagccaggac ttccctttcc cagagacacc
      601 agccaaagcg tggccacagg atgagtacat tgtggagtac tcgctggaat atggcttcct
      661 gcgactgtcg caagccacgc gccagcgcct gagcatccct gtcatggtag tcaccctaga
      721 ccccacgcgg gagcagtgct tcggggaccg cttcagccgc ctgctgctgg acgagttcct
      781 gggctacgac gacgtcctca tgtctagtgt gaagggcctg gcagagaatg aggagaacaa
      841 aggcttcttg aggaatgtgg tctctgggga gcactaccgc tttgtcagca tgtggatggc
      901 acgcacatcc tacctggcag cctttgtcat catggtcatc tttaccctca gtgtgtccat
      961 gctgttgcga tactcgcacc accagatctt cgtcttcatc gtggacctgc tgcagatgct
     1021 ggagatgaac atggccatcg ccttccccgc agcgcccttg ctgaccgtca tcctggctct
     1081 cgtcgggatg gaggccatca tgtctgagtt cttcaacgac accaccacgg ccttctacat
     1141 catcctcatc gtgtggctgg ccgaccagta cgatgccatc tgctgccaca ccaacaccag
     1201 caagcgacac tggctgaggt tcttctacct ctaccacttc gccttctacg cctaccacta
     1261 ccgctttaac ggccagtaca gcagcttggc cctggtcacg tcctggctct tcatccagca
     1321 ttccatgatc tacttcttcc accactatga gttgcccgcc atcctgcagc agatccgaat
     1381 ccaggagatg ctgttgcaga cacccccgct gggccctggg acccccacgg cgctgcctga
     1441 cgacctcaac aataactctg gctcccctgc caccccagat cccagtcctc ccctcgcgct
     1501 gggccccagc tccagccccg cgcccactgg cggagcatct gggcctggct cactgggcgc
     1561 tggggcctca gtatctggca gtgacctagg ttgggtggcc gagaccgccg ccatcatctc
     1621 ggacgcgtcc ttcctgtcgg ggctgagcgc ctcactgctg gagcggcggc cagcagcccc
     1681 cagtgccccg gacagcgcac gacctgaccc tggggcctct ctggaggacg cacctgcccc
     1741 tgccgggtcc tgagagcggt gtcgtgcctg gctcccggcg gagccgcggc ccgagcccaa
     1801 gagagctgtg gtctacaggg agaggggctg gcggcaaagg ttctggaagc ggccgggaca
     1861 gggcggcgat gggcacgagg ccaccggccg cctggtgctc cccagtgcct tccacacggc
     1921 gcccgcgcag ggccgagcgc ccgggcccgg actagcaggt ggcagctcag gacgcggcgc
     1981 tcacgttcca cgctatttaa ttgcagtgta cagagtcgtg tttgtatata gaataaactg
     2041 tcgtggacag tgaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa aaaaaaaaaa
//
