LOCUS       NM_001109528            2539 bp    mRNA    linear   ROD 14-MAR-2025
DEFINITION  Rattus norvegicus transmembrane protein 25 (Tmem25), transcript
            variant 3, mRNA.
ACCESSION   NM_001109528 XM_001060928
VERSION     NM_001109528.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 2539)
  AUTHORS   Zhang,H., Tian,X., Lu,X., Xu,D., Guo,Y., Dong,Z., Li,Y., Ma,Y.,
            Chen,C., Yang,Y., Yang,M., Yang,Y., Liu,F., Zhou,R., He,M., Xiao,F.
            and Wang,X.
  TITLE     TMEM25 modulates neuronal excitability and NMDA receptor subunit
            NR2B degradation
  JOURNAL   J Clin Invest 129 (9), 3864-3876 (2019)
   PUBMED   31424425
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473975.1.
            
            On Oct 4, 2007 this sequence version replaced XM_001060928.1.
            
            ##Evidence-Data-START##
            RNAseq introns :: partial sample support SAMD00132308, SAMEA5760393
                              [ECO:0000350]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..2539
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="8"
                     /map="8q22"
     gene            1..2539
                     /gene="Tmem25"
                     /note="transmembrane protein 25"
                     /db_xref="GeneID:689172"
                     /db_xref="RGD:1596132"
     exon            1..112
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
     exon            113..206
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
     CDS             137..1234
                     /gene="Tmem25"
                     /codon_start=1
                     /product="transmembrane protein 25 precursor"
                     /protein_id="NP_001102998.1"
                     /db_xref="GeneID:689172"
                     /db_xref="RGD:1596132"
                     /translation="MELPLSQATLRHTLLLLPALLSSGQGELAPQIDGQTWAERALRE
                     NEHHAFTCRVAGGSATPRLAWYLDGQLQKATTSRLLSVGGDAFSGGTSTFTVTAQRSQ
                     HELNCSLQDPGSGRPANASVILNVQFKPEIAQVGAKYQEAQGPGLLVVLFALVRANPP
                     ANVTWIDQDGPVTVNASDFLVLDAQNYPWLTNHTVQLQLRSLAHNLSVVATNDVGVTS
                     ASLPAPGLLATRIEVPLLGIVVAGGLAFGTLVGFSTLVACLVCRKEKKTKGPSRRPSL
                     ISSDSNNLKLNNVRLPRENMSLPSNLQLNDLTPDIRGKATERPMAQHSSRPELLEAEP
                     GGLLTSRGFIRLPMLGYIYRVSSVSSDEIWL"
     exon            207..518
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
     exon            519..809
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
     exon            810..941
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
     exon            942..972
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
     exon            973..1073
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
     exon            1074..1160
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
     exon            1161..2539
                     /gene="Tmem25"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ggagggagcc aggtgagctg cctggaaagc tggatgctcc aatgaccccc gggtccgcga
       61 cgctctcttg ctaggcccaa ttccatgttg aacagttgag attggaaaag ggcctggagg
      121 ccagtccctg atcaccatgg agttgcctct aagccaagct acgctccggc atactctgct
      181 gctcctgcct gccctcttaa gttcaggtca aggagagctg gcgccacaaa ttgatggtca
      241 gacctgggct gagagagcac ttagggaaaa tgagcaccat gctttcacct gtcgggttgc
      301 agggggttct gccactcccc gattagcctg gtacctggat ggacagctac agaaggctac
      361 cacctcgcga ctcctgagtg tgggcgggga cgccttctct ggaggtacca gcactttcac
      421 tgtcactgcc cagcgctccc aacatgagct taactgctcc ctgcaggacc cagggagtgg
      481 ccggccagcc aatgcctctg tcattctcaa tgtgcaattc aaaccagaga ttgcccaggt
      541 tggagccaag taccaggaag ctcagggccc aggccttctg gttgtcctgt ttgccctggt
      601 acgggccaac ccacctgcca atgtcacctg gattgaccag gatgggccag tgactgtcaa
      661 tgcctctgac ttcctggtgc tggatgccca gaactatccc tggctcacca accacactgt
      721 gcagctgcag ctccgaagcc tggcacacaa cctctcggtg gtggccacca acgatgtggg
      781 tgtcaccagt gcctcacttc cagctccagg gctcctggcc acacggatag aagtgccact
      841 gctgggcatc gttgtggctg gaggacttgc ctttggcact ctagtgggat tcagtacctt
      901 ggtggcctgc ctggtctgca ggaaagagaa gaaaacaaaa ggcccctccc ggcgtccttc
      961 tctgatatct agtgactcca ataacctgaa actgaataat gtgcgcctgc cccgggagaa
     1021 catgtccctc ccatccaacc ttcagctcaa tgacctcact ccggatatca gagggaaagc
     1081 aacagagcgg ccaatggctc agcatagcag ccgtccagag cttctagaag cggagcctgg
     1141 tggcctcctc accagccgag gtttcatccg tctcccaatg ttgggctaca tctaccgtgt
     1201 gtccagcgta agcagtgatg agatttggct ctgagcttga gagtgaggca gatggcccag
     1261 gtggtctgtg gactccccag agtgaccacc ccttcttgaa gcatcttctt caagcttccc
     1321 tctgcctggc cctgttgtga ccatgaagaa accatgtcac tgccgtctgg cctgcctggc
     1381 aaggatacct gtgggtcatg catgtgtatg tcattgcact ctaacctgca agacatgggt
     1441 acccttggca aggccacggg tcagaactaa gccccttgca ctcactcagt ttggggccct
     1501 gcatgtgata acctggtcca ggcagacgga actctggcca ggtgtgttta gatgtcaccc
     1561 gacacctaaa agacgggcct atttattata cgtcccacgc cagtatccac tgcaccttgt
     1621 gtgcagagag atgcctatgc aggggacccc gcacaactca gatgacagcc ttcctttgct
     1681 atgcagcctt gttccctcag ggaaaacata gcccctgcta ttgtatagaa ccaaattgcc
     1741 ctttgctcag gaaccagccc ctcacccagg gacctggcca agcacaaatt cgtccctttt
     1801 gctgcaacat atctttctac tcttctatcc ccacttcctc ttggtcatca taggtcatac
     1861 cctagacctt cttcactgag tattagacct ccattggctg gggcccatgg gtgcagcctt
     1921 tggtgttagc acaagatgag caagaagagg tgacaggagg gctggctccc aagacagcat
     1981 gtagcaatgt atcattttgt acagtgtcct catattaagc acattctcca ggagcgagga
     2041 gggcccaggg ccttcttggg ttccccatct ttggccttca gcaattcact gtgagtgttc
     2101 tgagcactca gggttggtgg tttcctctct gcatgtctct tcccaccatg cagccacatt
     2161 cctgaccaaa cctggctgcc acatcctatt cttccaggga tggtcacagt gggtatagaa
     2221 cccaacagcg ccagaagctt taggggaaca gagggagcag gagcccacac agctctaaag
     2281 agctaagaat acttttaaaa aagcaacatg aaaatggcaa acaggggttg gggatttagc
     2341 tcagtggtag agcgcttgcc tagcaagcgc aaggccctgg gttcagtccc cagctctgga
     2401 aaaaaaaaaa aaaaaaaaga aagaaaatgg caaacagcag agtatggagt ctattttcct
     2461 ttcttcatat cttgtttggt aatttttctt gtgttactgg tgagtactgt gctgcacaca
     2521 cagtaaattc ctttgacca
//
