LOCUS       NP_001406500             876 aa            linear   ROD 03-APR-2024
DEFINITION  transmembrane protein 245 [Rattus norvegicus].
ACCESSION   NP_001406500 XP_003749993
VERSION     NP_001406500.1
DBSOURCE    REFSEQ: accession NM_001419571.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            JAXUCZ010000005.1.
            
            On Apr 11, 2023 this sequence version replaced XP_003749993.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR26643298.27402.1,
                                           SRR26643289.15294.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMEA5760383,
                                           SAMEA5760386 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on manual assertion, conservation,
                                      expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..876
                     /organism="Rattus norvegicus"
                     /strain="BN"
                     /db_xref="taxon:10116"
                     /chromosome="5"
                     /map="5q24"
     Protein         1..876
                     /product="transmembrane protein 245"
                     /calculated_mol_wt=97151
     Region          1..32
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            2
                     /site_type="acetylation"
                     /note="N-acetylalanine.
                     /evidence=ECO:0000250|UniProtKB:B1AZA5; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            12
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:B1AZA5; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            16
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:B1AZA5; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            32
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q9H330; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            63..83
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            122..142
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            151..171
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            188..208
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            222..242
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            244..264
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            273..293
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Region          289..338
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            320
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H330; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            324
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H330; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            327
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0007744|PubMed:22673903; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            329
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H330; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            331
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q9H330; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            354..374
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            377..397
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            460..480
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            497
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            548
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            572
                     /site_type="glycosylation"
                     /note="N-linked (GlcNAc...) asparagine.
                     /evidence=ECO:0000255; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            626..646
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Region          <645..837
                     /region_name="PerM"
                     /note="Predicted PurR-regulated permease PerM [General
                     function prediction only]; COG0628"
                     /db_xref="CDD:440393"
     Site            650..670
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            734..754
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            755..775
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            779..799
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            818..838
                     /site_type="transmembrane region"
                     /note="propagated from UniProtKB/Swiss-Prot (D3ZXD8.1)"
     Site            874
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q9H330; propagated from
                     UniProtKB/Swiss-Prot (D3ZXD8.1)"
     CDS             1..876
                     /gene="Tmem245"
                     /gene_synonym="RGD1308958"
                     /coded_by="NM_001419571.2:10..2640"
                     /db_xref="GeneID:298020"
                     /db_xref="RGD:1308958"
ORIGIN      
        1 madrggpaee psprgsprse prvprtagps etprtaalal rfdkpikqaf yntgavlfvc
       61 lccgaavlvy fileaflrpl lwavlcgtfl hpfkssltrl grlwlrrlhr ahtpivlaal
      121 llplcfadyg vealgeqalr rrrlllllga ggpllyglyc lgsylgvqvl lahagalicr
      181 gldyfsslwi wtlvvgyvlm vsfkwnastq hylravsipv wmillfhias lagswripvf
      241 lvivflmsag tlyekqneke sagaelpgqv ismaastlan laisitgyes ssedqpsdps
      301 aeptdkgepp papsasssss srsspsspsp tlgrqrpemg tflrkkktsd iyfvslvwai
      361 iavqlwlnlw ivqllpvpva vwiikklvih fgvvgflekr crawwqvmes flkerqeala
      421 pwpitglgkf llkvdsklwh wlnkkmiiwl ekmldkiisi fiifllvigt lllallltak
      481 vhqesvhmie vtsslinetl anhpewanwl peaqvvqral nsaannvyqy grewithklh
      541 kilgdkvnnt aviekqvlel wdrlyhswfv knvthsgrhk ghkmhvsrqn swlgdildwq
      601 diasfvheni etflsilesl wivmsrnvsl lfttvttllt ilfysgtall nfvlsliifl
      661 ttlfyllsss deyykpvkwv isltplsqpg pssniigqsv eeairgvfda slkmagfygl
      721 ytwlthtvfg inivfipsal aailgavpfl gtywaavpav ldlwltqglg ckavlllvfh
      781 llptyfvdta iysdisgggh pyltglavag gayylglega iigpillcil vvasniysam
      841 lvsptnsmpt psqtpwpaqt qrtfrdised lkssvd
//
