LOCUS       NM_001108220            1891 bp    mRNA    linear   ROD 24-JUN-2024
DEFINITION  Rattus norvegicus transmembrane protein 237 (Tmem237), mRNA.
ACCESSION   NM_001108220 XM_001064402 XM_237179
VERSION     NM_001108220.1
KEYWORDS    RefSeq.
SOURCE      Rattus norvegicus (Norway rat)
  ORGANISM  Rattus norvegicus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Rattus.
REFERENCE   1  (bases 1 to 1891)
  AUTHORS   Huang,L., Szymanska,K., Jensen,V.L., Janecke,A.R., Innes,A.M.,
            Davis,E.E., Frosk,P., Li,C., Willer,J.R., Chodirker,B.N.,
            Greenberg,C.R., McLeod,D.R., Bernier,F.P., Chudley,A.E., Muller,T.,
            Shboul,M., Logan,C.V., Loucks,C.M., Beaulieu,C.L., Bowie,R.V.,
            Bell,S.M., Adkins,J., Zuniga,F.I., Ross,K.D., Wang,J., Ban,M.R.,
            Becker,C., Nurnberg,P., Douglas,S., Craft,C.M., Akimenko,M.A.,
            Hegele,R.A., Ober,C., Utermann,G., Bolz,H.J., Bulman,D.E.,
            Katsanis,N., Blacque,O.E., Doherty,D., Parboosingh,J.S.,
            Leroux,M.R., Johnson,C.A. and Boycott,K.M.
  TITLE     TMEM237 is mutated in individuals with a Joubert syndrome related
            disorder and expands the role of the TMEM family at the ciliary
            transition zone
  JOURNAL   Am J Hum Genet 89 (6), 713-730 (2011)
   PUBMED   22152675
REFERENCE   2  (bases 1 to 1891)
  AUTHORS   Zuniga,F.I. and Craft,C.M.
  TITLE     Deciphering the structure and function of Als2cr4 in the mouse
            retina
  JOURNAL   Invest Ophthalmol Vis Sci 51 (9), 4407-4415 (2010)
   PUBMED   20375344
REFERENCE   3  (bases 1 to 1891)
  AUTHORS   Ghosh,D., Lippert,D., Krokhin,O., Cortens,J.P. and Wilkins,J.A.
  TITLE     Defining the membrane proteome of NK cells
  JOURNAL   J Mass Spectrom 45 (1), 1-25 (2010)
   PUBMED   19946888
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from CH473965.2.
            
            On or before Oct 4, 2007 this sequence version replaced
            XM_001064402.1, XM_237179.4.
            
            ##Evidence-Data-START##
            RNAseq introns :: mixed sample support SAMD00132261, SAMD00132262
                              [ECO:0006172]
            ##Evidence-Data-END##
FEATURES             Location/Qualifiers
     source          1..1891
                     /organism="Rattus norvegicus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10116"
                     /chromosome="9"
                     /map="9q31"
     gene            1..1891
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /note="transmembrane protein 237"
                     /db_xref="GeneID:316412"
                     /db_xref="RGD:1306705"
     exon            1..173
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            174..205
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            206..262
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            263..400
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            401..518
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     CDS             463..1341
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /note="amyotrophic lateral sclerosis 2 (juvenile)
                     chromosome region, candidate 4"
                     /codon_start=1
                     /product="transmembrane protein 237"
                     /protein_id="NP_001101690.1"
                     /db_xref="GeneID:316412"
                     /db_xref="RGD:1306705"
                     /translation="MDVEPREEVVIPKPRRKAKKMQPAEPQYASELGVEDEDVITDEQ
                     STLEHHSRFTAPTGVSQPVGKIFVEKSRRFQAADRSELIKTTENVDVSMDMKPSWTTR
                     DVALSVHRAFRMIGLFSHGFLAGCAVWNIVVICVLAGDQFSNVSNLLQQYKPLAYPFQ
                     SLLYLLLALSTVSAFDRIDFAKTSVAIRNFLALEPTALASFLYFTALTLSLSQQMTSD
                     RIYLYEPSVNGSLWPAEVEEPVLMPWVIVNLVVALLVGLAWLFLSYRPGMDLSEELMF
                     FSDVDEYPERGVKASP"
     exon            519..676
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            677..800
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            801..992
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            993..1066
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1157
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1158..1279
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
     exon            1280..1891
                     /gene="Tmem237"
                     /gene_synonym="Als2cr4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacacctctg ggcggctctc ggctgcaggc aaagcgggag aggaggctgt ttccggtggg
       61 agcttgaatc ctggtctggt caagcggtgc tcatccccac gcaaatcgtg atgacctccc
      121 gggaaactgt gggtgaaccc cctccgctcc tggggacgtc gacatacgct gagcgtcctc
      181 cgcgagcact tccacctgtg ccaagatgag attccactta gtcatcctaa gaaaaagaaa
      241 tccagaacaa agagcacacc agctcctgct tcttcagaag gccttgctga gcccgttgtt
      301 aacaggaggg ctgagggcag tgagccacca gctgcagaac tcaaggagta cccagaggct
      361 cctgttcaaa ggaaacagaa gaagataaga ccacctcctg agttggagac ttccttcact
      421 gaaaagccat ccagtccgtc tttactacgg aatgaaaacg gcatggacgt ggagcctcgt
      481 gaggaagtgg ttattccaaa acctcgaagg aaggcgaaga aaatgcagcc agcggaacca
      541 cagtatgcca gcgagctagg ggtagaagat gaagacgtaa ttacggatga gcagagcact
      601 ctagaacacc actctaggtt caccgcaccc accggagtca gccagcctgt tggcaaaata
      661 tttgtggaaa aaagccggag atttcaggcg gcggaccgtt cggagttgat aaagaccaca
      721 gaaaacgtag atgtgtcaat ggacatgaag ccatcttgga ctacccgcga tgtggcactt
      781 tccgtgcacc gagctttcag gatgatcggc ctcttctctc acggcttctt ggctggctgt
      841 gctgtgtgga atattgttgt gatctgtgtt ctcgcgggag accagttctc taatgtctcc
      901 aaccttctgc agcagtacaa gcccttggca tatcccttcc agagccttct ttacttgctt
      961 ttggctctaa gtacagtttc agcatttgac aggatcgact ttgctaaaac ctcagtagca
     1021 atccggaact ttttggccct ggagccaaca gctttagcct ctttcttgta ttttactgct
     1081 ctaacactat ctctgagtca gcaaatgaca agtgacagaa tctaccttta cgaaccttct
     1141 gtcaatggaa gcctctggcc agcagaagtg gaggaaccgg ttctcatgcc atgggtcata
     1201 gtgaatctgg tggtggcgct tctggttgga ttagcctggc tctttttgtc ttacaggcca
     1261 ggcatggatc ttagtgaaga gttgatgttc ttttctgatg tggacgagta ccccgagaga
     1321 ggagtcaaag cgtctccgta gcgccggccg gctccgtccc tgcagtgacg gcctgcgttc
     1381 cccactcccg tttttaagtg tatttttata agatacatgt atttataatc gagcttttgt
     1441 tacataatgc tgaaatgcta ctgtagattg taaattatat ctggtcttta taccaaatat
     1501 tagggtcttt attattttca ccttagtgac acaggagata atgagctaaa acaaacaaac
     1561 aaacaaacaa aaaaacacag caggtgatgt gtttgtttcc tgtcctttca aatttgcaaa
     1621 attcatgatt attattagct aaagagcacc aatttagaaa agccttaacc tcagtgttat
     1681 aaaatataca tcaagtttaa atgtaaattt agtgaatggg gaagatggaa aaatgtcttc
     1741 attttatatt tttgatgtct tcttatggaa cactgcagga tgtgatttgt tttctctgaa
     1801 tctggctagt gttatagctc atataataat tatttgccat ttgaattgaa agatgcttta
     1861 tagctaataa aacagaaata cctatctttg a
//
